Investigator (Senior Bioanalyst/Associate Principal Scientist)
- GlaxoSmithKline
- Stevenage, Hertfordshire
- Sep 24, 2022
Full time
Government
Job Description
Site Name: UK - Hertfordshire - Stevenage
Posted Date: Sep
We're combining the power of genetic and genomic insights into what causes disease, with the speed and scale of artificial intelligence and machine learning (AI/ML) to make better predictions about who a treatment might work for, and why. We believe this powerful combination of data and technology holds the key to fundamentally transforming medical discovery for the better, improving R&D success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated.
In 2021 we delivered four major product approvals: Cabenuva for HIV, Jemperli for endometrial cancer, Xevudy for COVID-19 and Apretude, our new long-acting medicine for HIV prevention.
Find out more:
Our approach to R&D
Investigator (Senior Bioanalyst/Associate Principal Scientist)
(Immunoassay: Bioanalysis & Biomarkers)
We are seeking a motivated and experienced Bioanalyst to join our group based at our flagship R&D site in Stevenage, Hertfordshire. The team supports pharmacokinetic (PK) and soluble biomarker measurements for clinical studies using a variety of ligand binding assay techniques. The data we generate is critical to helping GSK Project Teams make decisions on progressing new molecules towards becoming medicines.
In this role you will independently develop and validate bespoke immunoassays for soluble biomarker and PK endpoints in support of clinical studies. You will be responsible for the delivery of high-quality large molecule bioanalytical assay data to study teams for early stage clinical studies (e.g. enabling and FTiH). You will also be required to act as a subject matter expert in support of our CRO partners, working to ensure that assay transfers proceed smoothly prior to later stage clinical studies.
In this role you will
Closing Date for Applications: 6th October (COB)
Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact . This will help us to understand any modifications we may need to make to support you throughout our selection process.
LI-GSK
Why you?
Qualifications & Skills:
We are looking for professionals with these required skills to achieve our goals:
Preferred Qualifications & Skills:
If you have the following characteristics, it would be a plus:
Why GSK?
Uniting science, technology and talent to get ahead of disease together
GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued and included. Where they can keep growing and look after their wellbeing.So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
Find out more:
Annual Report 2021
GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.
As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class ( US only).
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
Please don't hesitate to contact us if you'd like to discuss any adjustments to our process which might help you demonstrate your strengths and capabilities.You can either call us on , or send an email
As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it.Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK..... click apply for full job details
Posted Date: Sep
We're combining the power of genetic and genomic insights into what causes disease, with the speed and scale of artificial intelligence and machine learning (AI/ML) to make better predictions about who a treatment might work for, and why. We believe this powerful combination of data and technology holds the key to fundamentally transforming medical discovery for the better, improving R&D success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated.
In 2021 we delivered four major product approvals: Cabenuva for HIV, Jemperli for endometrial cancer, Xevudy for COVID-19 and Apretude, our new long-acting medicine for HIV prevention.
Find out more:
Our approach to R&D
Investigator (Senior Bioanalyst/Associate Principal Scientist)
(Immunoassay: Bioanalysis & Biomarkers)
We are seeking a motivated and experienced Bioanalyst to join our group based at our flagship R&D site in Stevenage, Hertfordshire. The team supports pharmacokinetic (PK) and soluble biomarker measurements for clinical studies using a variety of ligand binding assay techniques. The data we generate is critical to helping GSK Project Teams make decisions on progressing new molecules towards becoming medicines.
In this role you will independently develop and validate bespoke immunoassays for soluble biomarker and PK endpoints in support of clinical studies. You will be responsible for the delivery of high-quality large molecule bioanalytical assay data to study teams for early stage clinical studies (e.g. enabling and FTiH). You will also be required to act as a subject matter expert in support of our CRO partners, working to ensure that assay transfers proceed smoothly prior to later stage clinical studies.
In this role you will
- Provide scientific leadership and set strategic direction on emerging technologies
- Build effective relationships with the various supported groups within and outside the department to balance stakeholder expectations with scientific quality and validation requirements ensuring limitations of assays and data are well understood
- Hold yourself accountable for delivering high quality bioanalytical results, managing timelines whilst being fully compliant with GCP regulatory requirements
- Adopt a technology agnostic attitude and openness to analytical techniques when planning support for all modalities
- Work as part of the team to ensure day-to-day laboratory responsibilities are met (reviewing study plans/reports etc)
- Drive the departments "automation first" objective for both the laboratory work and the pre-analytical and post-analytical workflows
- Partner with external companies, institutes and consortium to deliver solutions
- Well-connected in the analytical community established through publications and presentations at national and international conferences
- Drive innovation and actively contribute to process improvements (scientific, regulatory/quality)
Closing Date for Applications: 6th October (COB)
Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact . This will help us to understand any modifications we may need to make to support you throughout our selection process.
LI-GSK
Why you?
Qualifications & Skills:
We are looking for professionals with these required skills to achieve our goals:
- Graduate degree in biology, biochemistry or pharmacology
- Extensive experience running Bioanalytical or Biomarker studies in a GxP regulated environment with a focus on good record keeping and data integrity
- Experience in the method development and validation of quantitative immunoassays using one or more of the following Gyrolab, MSD, Simoa, SMCxPRO (or Erenna)
- Ability to effectively manage multiple priorities, communicate recommendations clearly and enjoy working within a team
- Ability to present both written and oral communications to R&D stakeholders
Preferred Qualifications & Skills:
If you have the following characteristics, it would be a plus:
- PhD degree in biology, biochemistry or pharmacology
- Understanding of regulatory aspects of human biological sample management, Good Clinical Practice (GCP)
- Experience of interacting with LabQA/regulatory inspectors
- Experience in tailoring bespoke biomarker assay validations to the context of use for the data
- Experience with automated liquid handling platforms (e.g. Labcyte Echo, SPT Labtech DragonFly, Agilent BRAVO, Hamilton STAR)
- Thorough understanding of the drug development process
- Experience using Thermo Watson LIMS
Why GSK?
Uniting science, technology and talent to get ahead of disease together
GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued and included. Where they can keep growing and look after their wellbeing.So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
Find out more:
Annual Report 2021
GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.
As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class ( US only).
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
Please don't hesitate to contact us if you'd like to discuss any adjustments to our process which might help you demonstrate your strengths and capabilities.You can either call us on , or send an email
As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it.Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK..... click apply for full job details
About GlaxoSmithKline