GlaxoSmithKline

Principal Scientist, Translational Data SciencesClosing Date: 2nd September 2026 (COB)Business IntroductionAt GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together.Find out more:Our approach to R&DFor candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029 .Position SummaryYou will lead translational data science efforts that turn human genetics and multi-omic data into clear decisions for drug discovery. You will work closely with experimental scientists, biostatisticians, data engineers, AI researchers and clinical teams. We value clear communication, practical problem solving, curiosity and collaboration. This role offers visible impact, career growth, and aligns with our mission of uniting science, technology and talent to get ahead of disease together.ResponsibilitiesThis role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:- Design and run rigorous, reproducible analyses of large-scale genetic and multi-omic datasets to address translational questions.- Integrate genetics, proteomics, transcriptomics and clinical data to prioritise targets, nominate biomarkers, and define patient subgroups.- Build and maintain analysis workflows and tools following reproducible research and FAIR data principles.- Translate analytic results into clear recommendations for project teams and leaders.- Collaborate across functions and with external partners to shape study design, data generation and interpretation.- Mentor and support junior colleagues to share methods, standards and practical best practice.Why You?Basic QualificationWe are seeking professionals with the following required skills and qualifications to help us achieve our goals.Physical sciences (Maths, Computer Science, Physics, Chemistry, Engineering etc) or Biological sciences (Biology, Biochemistry, Bioengineering etc) undergraduate degree or Medical degree.PhD in data science, computer science, computational biology, bioinformatics, or a closely related discipline.Strong hands-on experience analysing large-scale genetic and multi-omic datasets.Proficient programming skills in Python and experience with reproducible workflows and version control.Experience integrating molecular data with clinical or phenotypic data to answer translational questions.Proven ability to communicate complex results clearly to scientific and non-technical audiences.Willingness and ability to work in a hybrid model with regular on-site presence in the United Kingdom as required by the Performance with Choice policy.Preferred QualificationIf you have the following characteristics, it would be a plus:Track record of peer-reviewed publications or major scientific contributions in genetics or translational genomics.Experience with cloud or distributed computing platforms and large-scale data processing tools.Familiarity with causal inference, biomarker discovery, and patient stratification methods.Experience with single-cell, spatial omics, proteomics or other emerging molecular technologies.Experience working within multi-disciplinary project teams in industry or academia.Experience contributing to production-ready pipelines or shared analysis platforms.Location and Working ModelThis role is based in the United Kingdom. The position is offered on a hybrid working model that combines time working remotely and time in office to support collaboration and development.How to ApplyWe welcome applicants from all backgrounds. If this role matches your skills and interests, please apply and tell us how your experience maps to the responsibilities and qualifications above. We look forward to learning about the impact you could make at GSKSkillsApplied Statistics, Data Analysis, Data Engineering, Data Science, Datasets, Drug Development, Drug Discovery Process, Drug Target Identification, Genetic Analysis, Genomic Analysis, Machine Learning (ML), Software EngineeringGermany Salary Range / Gehaltsbandbreiten Deutschland: EUR 74,250 to EUR 123,750For positions covered by collective bargaining, employment conditions and remuneration are determined by the applicable collective agreements for the chemical industry as well as internal policies. More detailed information on compensation will be provided during the recruitment process. Depending on the role and internal policies, the position may also be eligible for a bonus (if applicable and based on defined, non-discretionary criteria) and/or awards for exceptional performance (granted at the employer's discretion). All benefits arising from the applicable collective bargaining agreement, such as holiday allowance and additional paid time off, will be provided in full, in accordance with that agreement and German law. Other benefits may also be offered, which may include health & wellbeing benefits, pension plan and paid parental leave & care of family member leave.Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at

GlaxoSmithKline is seeking a senior engineering leader to recruit, mentor and scale a high-performing full-stack software organization focused on enterprise-quality delivery and data-driven platforms in the UK. You will partner with Product, DevOps, and Platform teams to drive product roadmaps, implement modern architecture, and foster a culture of observability, automation, and user-centric design across global engineering teams.

GSK is seeking a senior Regulatory Affairs leader in the United Kingdom to shape regulatory lifecycle strategy and lead global interactions. The role requires working with MDT/EDT teams, managing a matrix team, and ensuring compliant labeling and lifecycle expansion across key markets. You will oversee regulatory strategy development, drive submissions, and maintain strong relationships with Health Authorities. Hybrid working model with on-site leadership duties in Stevenage/Cambridge, UK.

Business Introduction At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D Position Summary Ensure the development of appropriate regulatory life cycle strategy(s) and their execution for assigned asset(s) consistent with Medicines Development Strategy/Integrated Asset Plan (IAP) to ensure the development program meets the needs of the key markets identified and the Medicine Profile. This goal has to be achieved while ensuring compliance with both internal GSK process / policy and with appropriate regulatory requirements to deliver the best possible life cycle management, expansion and labeling to meet the Medicine Profile, commensurate with the available data. Position will have direct reports. Responsibilities Accountable to Global Regulatory Strategy Therapeutic Area Head for development of appropriate regulatory life-cycle management and expansion strategy(s) and for delivery according to plans. In conducting role, planning will be on a multiple year horizon, with delivery requiring extensive matrix working within GSK to VP level and including representing GSK with regulatory agencies as appropriate. Works with the Early/Medicine Development Team (EDT/MDT) to ensure a robust regulatory strategy is in place to support the development program and/or strategic activities for GSK's Established Products (EP) portfolio to meet the needs of the key markets identified in the IAP and the Medicine Profile. Once prioritized by the MDT, work closely with the global commercial team and local regulatory teams in prioritized countries to secure / maintain the best possible labelling commensurate with available data and in line with the GDS. When a team leader Provides direct line management responsibility for TG staff Ability to attract talent, challenge and manage and develop direct reports Manage performance for direct reports (e.g. My Plan, Reward, Recognition, PIPs, etc.) Is an active contributor to the Therapeutic Group LT but also drives specific topics such as resource demands and workforce planning Understands well and is able to drive resource management conversations including new assignments, gap identifications, while taking into account individual's needs Assist in managing TG budget Provide regulatory advice for urgent incident / PIRC / crisis management including ensuring regulatory reporting requirements are met. When a GRL Proactively develop a regulatory strategy focused on the key markets identified. In doing so, will promote innovative regulatory approaches when they benefit advancement of a given program. Ensure implementation of the regulatory strategy(s) in support of the project priorities. Assess precedent, regulatory intelligence and competitive environment from a regulatory perspective and the impact this will have on the regulatory strategy for an asset. Lead regulatory interactions and the regulatory review processes Ensure effective interaction with local regulatory counterparts in priority markets and global commercial teams Ensure compliance with regulatory requirements at all stages of product life Advocate persuasively to senior leaders in GSK and in Health Authorities Work alongside other core members of the MDT and/or EDT providing broad development input/expertise to their programs (over and above regulatory input). Act as single point of accountability on the EDT/MDT, lead the Regulatory Matrix Team, and deliver the required Regulatory Work Package(s) associated with the IAP. Capable of providing critical regulatory assessment as part of due diligence/business development activities Why You? Basic Qualification Bachelor's degree in a life science, pharmacy, medicine, or related discipline. Extensive experience of all phases of the drug development process in regulatory affairs, including maintenance and lifecycle management of marketed products, and projects with little or no precedence. Extensive knowledge of relevant therapeutic area or proven track record of being able to develop product / therapeutic knowledge in new area. Proven experience of leading development, submission and approval activities including track record of organizing and executing successful milestone meetings and proven track record of successful relationship with one or more Health Authority Extensive knowledge of clinical trial and licensing requirements in priority markets and sound knowledge globally. Ideally, proven experience of leading regulatory activities outside local region. Experience in resource management and forecasting. Preferred Qualification Advanced degree (MSc, PharmD, PhD) or equivalent professional qualification. Experience managing budgets, external vendor relationships and centre-of-excellence style teams. Proven success with inspection readiness and managing regulatory compliance programmes. Experience in Line management and Matrix team working Strong track record of coaching, developing and attracting regulatory talent. Location and Working Model This role is based in the United Kingdom and operates in a hybrid working model. You will be expected to spend regular time on-site to lead the team and work with cross-functional colleagues. For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029. Skills Business Resilience Communication Digital Fluency Matrix Leadership Pharmaceutical Regulatory Compliance Policy Advocacy Regulatory Strategies Resource Management Stakeholder Management Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Business Introduction At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D Position Summary Ensure the development of appropriate regulatory life cycle strategy(s) and their execution for assigned asset(s) consistent with Medicines Development Strategy/Integrated Asset Plan (IAP) to ensure the development program meets the needs of the key markets identified and the Medicine Profile. This goal has to be achieved while ensuring compliance with both internal GSK process / policy and with appropriate regulatory requirements to deliver the best possible life cycle management, expansion and labeling to meet the Medicine Profile, commensurate with the available data. Position will have direct reports. Responsibilities Accountable to Global Regulatory Strategy Therapeutic Area Head for development of appropriate regulatory life-cycle management and expansion strategy(s) and for delivery according to plans. In conducting role, planning will be on a multiple year horizon, with delivery requiring extensive matrix working within GSK to VP level and including representing GSK with regulatory agencies as appropriate. Works with the Early/Medicine Development Team (EDT/MDT) to ensure a robust regulatory strategy is in place to support the development program and/or strategic activities for GSK's Established Products (EP) portfolio to meet the needs of the key markets identified in the IAP and the Medicine Profile. Once prioritized by the MDT, work closely with the global commercial team and local regulatory teams in prioritized countries to secure / maintain the best possible labelling commensurate with available data and in line with the GDS. When a team leader Provides direct line management responsibility for TG staff Ability to attract talent, challenge and manage and develop direct reports Manage performance for direct reports (e.g. My Plan, Reward, Recognition, PIPs, etc.) Is an active contributor to the Therapeutic Group LT but also drives specific topics such as resource demands and workforce planning Understands well and is able to drive resource management conversations including new assignments, gap identifications, while taking into account individual's needs Assist in managing TG budget Provide regulatory advice for urgent incident / PIRC / crisis management including ensuring regulatory reporting requirements are met. When a GRL Proactively develop a regulatory strategy focused on the key markets identified. In doing so, will promote innovative regulatory approaches when they benefit advancement of a given program. Ensure implementation of the regulatory strategy(s) in support of the project priorities. Assess precedent, regulatory intelligence and competitive environment from a regulatory perspective and the impact this will have on the regulatory strategy for an asset. Lead regulatory interactions and the regulatory review processes Ensure effective interaction with local regulatory counterparts in priority markets and global commercial teams Ensure compliance with regulatory requirements at all stages of product life Advocate persuasively to senior leaders in GSK and in Health Authorities Work alongside other core members of the MDT and/or EDT providing broad development input/expertise to their programs (over and above regulatory input). Act as single point of accountability on the EDT/MDT, lead the Regulatory Matrix Team, and deliver the required Regulatory Work Package(s) associated with the IAP. Capable of providing critical regulatory assessment as part of due diligence/business development activities Why You? Basic Qualification Bachelor's degree in a life science, pharmacy, medicine, or related discipline. Extensive experience of all phases of the drug development process in regulatory affairs, including maintenance and lifecycle management of marketed products, and projects with little or no precedence. Extensive knowledge of relevant therapeutic area or proven track record of being able to develop product / therapeutic knowledge in new area. Proven experience of leading development, submission and approval activities including track record of organizing and executing successful milestone meetings and proven track record of successful relationship with one or more Health Authority Extensive knowledge of clinical trial and licensing requirements in priority markets and sound knowledge globally. Ideally, proven experience of leading regulatory activities outside local region. Experience in resource management and forecasting. Preferred Qualification Advanced degree (MSc, PharmD, PhD) or equivalent professional qualification. Experience managing budgets, external vendor relationships and centre-of-excellence style teams. Proven success with inspection readiness and managing regulatory compliance programmes. Experience in Line management and Matrix team working Strong track record of coaching, developing and attracting regulatory talent. Location and Working Model This role is based in the United Kingdom and operates in a hybrid working model. You will be expected to spend regular time on-site to lead the team and work with cross-functional colleagues. For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029. Skills Business Resilience Communication Digital Fluency Matrix Leadership Pharmaceutical Regulatory Compliance Policy Advocacy Regulatory Strategies Resource Management Stakeholder Management Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

GSK is seeking a senior Regulatory Affairs leader in the United Kingdom to shape regulatory lifecycle strategy and lead global interactions. The role requires working with MDT/EDT teams, managing a matrix team, and ensuring compliant labeling and lifecycle expansion across key markets. You will oversee regulatory strategy development, drive submissions, and maintain strong relationships with Health Authorities. Hybrid working model with on-site leadership duties in Stevenage/Cambridge, UK.

GSK is seeking a Clinical Development Senior Medical Director to lead cardiovascular medicine programs within the RIIRU. You will shape translational and clinical plans, drive study designs, and oversee medical governance across early and later phase studies. This role requires strong cross-functional leadership and a deep understanding of regulatory and safety frameworks. You will collaborate with safety, regulatory, translational science, and commercial teams to advance medicines for vascular

GlaxoSmithKline is seeking a Biologist/Computational Scientist to lead predictive and agentic workflows for prioritising targets in drug discovery. You will combine computational and experimental approaches to predict biology, safety and translational potential, collaborating with biologists, data scientists and project teams to influence decisions. This hybrid role offers visibility, career growth and opportunities to unite science, technology and talent to accelerate medicines for patients.

Business Introduction At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge UK, in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029. Position Summary You will lead predictive and agentic target biology work to improve how we find and prioritise targets for new medicines. You will combine computational and experimental approaches to predict target biology, safety, and translational potential. You will work closely with biologists, data scientists, engineers and project teams to influence project decisions. We value clear communicators who build robust, reproducible methods and focus on practical impact for patients. This role offers visible project influence, career growth, and the chance to unite science, technology and talent to get ahead of disease together. This role will provide you the opportunity to lead key activities to progress your career. These responsibilities include some of the following: Lead development and application of predictive models and agentic workflows to evaluate target tractability and safety. Design hypothesis-driven experiments and computational tests to validate target biology and mechanism of action. Integrate multimodal biological data such as genomics, transcriptomics, proteomics and functional screens. Translate biological questions into clear computational and experimental plans and deliver documented pipelines. Provide timely, evidence-based recommendations to project teams for target prioritisation and go/no-go decisions. Mentor colleagues and promote best practices in model validation, reproducibility and transparent reporting. Basic Qualification PhD in biology, computational biology, bioinformatics, systems biology or a related life sciences field; or MSc with substantial relevant experience. Practical experience developing and applying predictive models for biological targets or cellular phenotypes. Strong programming skills in Python or similar languages and experience with scientific libraries for data analysis. Hands on experience integrating and analysing multimodal biological datasets including RNA seq, proteomics or CRISPR screens. Proven track record working in multidisciplinary teams and translating research questions into actionable workflows. Right to work in the United Kingdom. Preferred Qualification Experience with agentic systems or orchestration frameworks that automate iterative design test analyse cycles. Familiarity with causal inference, mechanistic models, or systems biology methods for predicting biology. Experience deploying models and workflows to cloud or production environments such as Kubernetes, AWS or Azure. Knowledge of target safety assessment, translational biomarkers, or early pharmacology relevant to discovery. Record of scientific communication through publications, conference presentations or internal knowledge sharing. Experience mentoring or leading small scientific teams and influencing cross functional decisions. Working Pattern This role is hybrid. You will combine remote work with regular in-office time in the United Kingdom to collaborate with colleagues and project teams. Skills Artificial Intelligence (AI), Computational Sciences, Computer Programming, Data Analysis, Data Management, Data Modeling, Data Science, Predictive Modeling, Statistical Models. We welcome applicants from all backgrounds and encourage people who may not meet every preference to apply. We look forward to learning about the impact you want to make. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the Link where you will find answers to multiple questions we receive. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at We are a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Find out more on our career site.

GlaxoSmithKline is seeking an Interventional Study Scientist Director to lead the scientific design and execution of clinical studies. This role focuses on oncology and involves collaboration with cross-functional teams to ensure high-quality studies that align with strategic objectives. Candidates should possess an advanced scientific degree and substantial clinical research experience. GSK values innovation, inclusion, and offers flexible working arrangements as part of its commitment to a healthy work-life balance.

Interventional Study Scientist Director Locations: GSK HQ, New Oxford Street & USA - Upper Providence Reports to: Head of Interventional & Supported Studies Join GSK's Medical Affairs team and be part of a global organization that drives innovation, scientific excellence, and patient-centered solutions. As a member of the Medical Affairs organization, you'll collaborate with cross-functional teams to shape clinical practice, engage with healthcare professionals, and deliver on our promise to help people do more, feel better, and live longer. This role offers an exciting opportunity to lead the scientific design and execution of interventional clinical studies within the Medical Affairs organization for oncology or hematology assets. You will shape data generation strategies, ensure studies are conducted with the highest standards of quality and ethics, and collaborate with cross-functional teams to deliver impactful results. In this role, you will: Design and oversee interventional clinical studies, ensuring alignment with strategic objectives and evidence plans. Provide scientific oversight for study protocols, analysis plans, and interpretation of study data. Ensure patient safety and scientific integrity throughout study conduct, including medical governance and monitoring. Collaborate with cross-functional teams to ensure seamless execution and delivery of clinical programs. Prepare and present study results for scientific meetings, publications, and regulatory submissions. Engage with internal and external stakeholders, including investigators and thought leaders, to enhance study design and execution. Basic Qualifications & Skills Advanced degree in a relevant scientific discipline (MD, PhD, PharmD, or equivalent). Specialized experience in oncology, pulmonology, hepatology or a related therapeutic area. Considerable experience in clinical research, including interventional studies. Proven experience designing and executing clinical trials with demonstrated impact. Strong understanding of regulatory requirements and industry best practices for clinical research. Experience leading cross-functional teams in a matrixed environment. Excellent communication and organizational skills. Preferred Qualifications & Skills Experience leading multi-country or global interventional studies. Experience collaborating with regulatory authorities. Familiarity with innovative approaches in clinical trial design and execution. Exposure to working with key opinion leaders, investigators, and external partners. Experience developing scientific content for publications and regulatory submissions. Understanding of digital tools and methodologies for evidence generation. What we offer You will join a team focused on scientific rigour and patient impact. You will gain leadership exposure across functions and grow your clinical development expertise. We value inclusion, work-life balance, and career development. We offer a flexible working culture. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Site Name: UK - Hertfordshire - Stevenage, GSK HQ, USA - Massachusetts - Waltham, USA - North Carolina - Durham, USA - Pennsylvania - Upper Providence Posted Date: May 5 2026 Director, Translational Science Lead - Respiratory R&D Translational Sciences, part of the newly formed Translational & Developmental Sciences (TDS), is accountable for end-to-end disease area translational science to inform therapy area and program level biomarker strategies (from preclinical to launch) to increase the probability of success from preclinical to clinical transitions and enable earlier and higher confidence asset related decisions. This includes generation of foundational data as well as disease biomarker development and validation that allow timely deployment of tools/biomarkers to support Proof of Mechanism (PoM), signs of clinical efficacy, Proof of Concept (PoC), and pairing Mechanisms of Action (MoAs) with patient subtypes to predict responder populations. We are looking for a dynamic individual to excel in the following responsibilities. Key Responsibilities: Disease Biomarker Strategy Development and Delivery: Partner with the Clinical Teams, R&D Technologies and the RIIRU Early Pipeline Unit with focus on Respiratory portfolio to identify, establish biomarkers for decision making throughout clinical development phases and aligned with the overall research and development goals. This will include the identification, prioritisation and validation of disease relevant biomarkers, mechanistic/surrogate biomarkers, patient stratification, and differentiated response prediction, their deployment into clinical studies and interpretation of data/results. Translational Leadership: Provide strategic leadership contributing to deep understanding of disease areas enabling the development and execution of translational research disease strategies to support the discovery and development of novel differentiated therapeutics including evaluation and diligence of business development opportunities. Translational innovation: Evaluate novel techniques and technologies (i.e. spatial transcriptomics) to inform translational initiatives, biomarker development and validation working in collaboration with platform teams and within a multi-functional matrix environment. Identify and guide validation of human assays (cells, tissues and organs) to enhance human translation and predictive value through the application of resources such as the Human Cell Atlas, disease tissue multi-omics data and genetic resources (external or proprietary). Cross-functional Collaboration: Collaborate closely with cross-functional teams including the Translational Disease Teams, biology groups, biomarker platforms, Medicine Development Teams, HBSM, data-sciences, regulatory affairs, business development and commercial to ensure seamless integration of translational research and biomarker strategies across the drug development lifecycle. External Partnerships: Establish and maintain strategic collaborations with academic institutions, contract research organizations (CROs), and other external partners to access cutting-edge technologies, tools, reagents, biosamples, biomarker expertise, and research capabilities. o Foster a network of external experts and key opinion leaders to stay at the forefront of translational science and biomarker advancements across the industry. Contribute to evaluation and diligence of business development opportunities. Matrix Leadership: Provide mentorship, guidance, and professional development opportunities to ensure a high-performing and motivated team. Manage disease and project level resources, budgets, and timelines to ensure the successful execution of projects and achievement of milestones and R&D Translational Science objectives. Represent Translational Science at portfolio governance reviews providing critical input to pipeline and investment decision making. Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: Ph.D. in a Scientific / Life Science discipline (e.g., Cell/Molecular Biology, Genetics, Pharmacology, Physical Chemistry or related field). Extensive experience in translational science and biomarker development ideally within the pharmaceutical or biotechnology industry. Recognized translational/biomarker expert in scientific community through publications and contributions to the field. Experience of translation and biomarkers implementation in Respiratory indications. Experience of working in a clinical trial setting, working as part of a clinical study and experience of authoring and oversight of clinical and regulatory documents. Experience / working knowledge of regulatory requirements, industry standards, best practices and compliance considerations in Translational Research and biomarker development and validation. Experience in technologies and methods used in translational research. Proven track record of program decision making through implementing biomarker strategies and delivering translational science insights in support of drug progression through clinical transition milestones. Experience leading/managing external collaborations and evaluation of business development opportunities. Experienced matrix leader with the ability to create psychological safety, inspire and motivate a team towards achieving common goals. Preferred Qualifications: If you have the following characteristics, it would be a plus: Awareness of bioinformatic / computational methods supporting integrated analysis and interpretation of translational and biomarker-related data sets. Strong management skills, with the ability to prioritize and manage multiple objectives to meet timelines while maintaining attention to detail and high-performance standards. Experience adapting to fast-paced and evolving research environments, with strong problem-solving and critical-thinking skills. Work Location: This role is based in the United Kingdom or the United States and offers a hybrid working model, combining on-site and remote work flexibility. Join us in shaping the future of translational science and making a meaningful impact on patients' lives. • If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $189,750 to $316,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. 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