Biomarker Statisticians to Statistical Leaders - UK - US
- GlaxoSmithKline
- Stevenage, Hertfordshire
- Sep 21, 2022
Full time
Healthcare & Medical
Job Description
Site Name: USA - Pennsylvania - Upper Providence, UK - Hertfordshire - Stevenage
Posted Date: Jul
GSK's Non-Clinical and Translational Statistics group plays a vital part at the birth of many prospective medicines and therapies through its work in helping top laboratory and product development teams, from the earliest stages of drug discovery through to the successful launch of new medicines. Our advanced modelling enables scientists to unravel the mechanisms of human disease, evaluate competing theories and explore potential new treatments using high-dimensional genomic and bioimaging data.
The successful candidate for this Leader level position within the Translational and Biomarker Statistics team will serve as an expert scientific and functional leader. In this role, you will have the opportunity to be closely engaged in developing biomarker objectives for clinical projects, influencing translational medicine efforts and the development of companion diagnostics.
Key Responsibilities
Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact . This will help us to understand any modifications we may need to make to support you throughout our selection process.
LI-GSK
Why you?
Basic Qualifications
We are looking for professionals with these required skills to achieve our goals:
Preferred Qualifications
If you have the following characteristics, it would be a plus:
Why GSK?
GSK is a place where outstanding people do amazing things. As a science-led global healthcare company, we exist to help people do more, feel better, live longer. This special purpose - along with our goal of being one of the world's most innovative, best performing and trusted healthcare companies - helps us attract some of the best and brightest minds in the world.
We take pride in providing access to all and continually focus on our opportunity and obligation to do more to improve inclusion and diversity: for our people inside GSK; in the way we do business; and in the communities where we operate.
We want our company to be a place where diversity of people and thought is valued everywhere and where we're all able to be ourselves and feel a sense of belonging. An inclusive organization where we all feel valued, engaged and supported, knowing that our work makes an important contribution to our mission. Reinforced by our clear values and expectations, it is part of our DNA. Together we achieve extraordinary things for our patients and consumers, who rely on us each and every day.
If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1- (US Toll Free) or +1 (outside US).
GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve.
GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.
Posted Date: Jul
GSK's Non-Clinical and Translational Statistics group plays a vital part at the birth of many prospective medicines and therapies through its work in helping top laboratory and product development teams, from the earliest stages of drug discovery through to the successful launch of new medicines. Our advanced modelling enables scientists to unravel the mechanisms of human disease, evaluate competing theories and explore potential new treatments using high-dimensional genomic and bioimaging data.
The successful candidate for this Leader level position within the Translational and Biomarker Statistics team will serve as an expert scientific and functional leader. In this role, you will have the opportunity to be closely engaged in developing biomarker objectives for clinical projects, influencing translational medicine efforts and the development of companion diagnostics.
Key Responsibilities
- Manage the assigned biomarker projects and provide timely support across all phases of drug development pipeline in collaboration with other functional area scientists.
- Propose and implement optimal and fit-for-purpose statistical and computational solutions for various biomarker studies.
- Identify and implement ways to improve efficiency of biomarker support such as development of tools for automation of data analysis and visualization.
- Embrace a wide range of classical and modern data analytic and predictive modelling (machine learning) methods and lead the development and evaluation of new methods and algorithms for research topics of greatest need.
- Significantly contribute to the external scientific community via conference presentations, publications and collaborations.
- Ensure the statistical robustness of prediction models such that all relevant uncertainty is correctly propagated through such models in order to inform the estimate of risk-discharge for any particular development plan option.
Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact . This will help us to understand any modifications we may need to make to support you throughout our selection process.
LI-GSK
Why you?
Basic Qualifications
We are looking for professionals with these required skills to achieve our goals:
- Master's degree in Statistics or Biostatistics
- Working experience in pharmaceutical industry
- Proven experience in a wide range of classical and modern statistical and machine learning methods, with good external reputation via strong publications and conference presentations.
- Demonstrated ability to apply innovative and fit-for-purpose statistical and predictive modelling methods for the analysis of biomarker and high dimensional data from clinical trials.
Preferred Qualifications
If you have the following characteristics, it would be a plus:
- PhD in statistics, computational methods or related field with focus on methods for genomics and related high-dimensional data analysis.
- Experience in early Drug Discovery
- Proven ability to learn, derive and apply innovative methodologies
- Good understanding of nonlinear mixed effects (Bayesian) models, the Pharmacometrics literature, and PK/PD modeling in general. A Bayesian mindset is an advantage.
- Strong communication skills both verbally and in writing
- Good collaboration and influencing skills in matrix working environments
Why GSK?
GSK is a place where outstanding people do amazing things. As a science-led global healthcare company, we exist to help people do more, feel better, live longer. This special purpose - along with our goal of being one of the world's most innovative, best performing and trusted healthcare companies - helps us attract some of the best and brightest minds in the world.
We take pride in providing access to all and continually focus on our opportunity and obligation to do more to improve inclusion and diversity: for our people inside GSK; in the way we do business; and in the communities where we operate.
We want our company to be a place where diversity of people and thought is valued everywhere and where we're all able to be ourselves and feel a sense of belonging. An inclusive organization where we all feel valued, engaged and supported, knowing that our work makes an important contribution to our mission. Reinforced by our clear values and expectations, it is part of our DNA. Together we achieve extraordinary things for our patients and consumers, who rely on us each and every day.
If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1- (US Toll Free) or +1 (outside US).
GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve.
GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.
About GlaxoSmithKline