Biomarker Principal Programmer/Analyst, Data Strategy Principal Programmer/Analyst --Data Strategy Programming Leader UK - US - CAN - Remote

Site Name: USA - Pennsylvania - Upper Providence, Collegeville TSA, UK - Hertfordshire - Stevenage, UK - London - Brentford, USA - Massachusetts - Waltham, USA - Pennsylvania - Marietta
Posted Date: Aug

Please note it is your responsibility to notify your manager if you are interested in applying to an open position prior to the interview taking place. Please refer to your local policy for more information and guidelines.

Oncology Biomarker Programming is committed to supporting the development of novel Oncology therapies via our exploratory Biomarker work. Current GSK Oncology portfolio consists of four key therapy areas: Immuno-Oncology, Oncology Cell & Gene Therapy, Synthetic Lethality, and Tumour Cell Targeting.

US Hiring Locations: Collegeville, PA and Waltham, MA

Canada Hiring Locations : Mississauga

UK Hiring Locations: Stevenage, GSK House

EU Hiring Locations: Netherlands, Belgium

Remote Working: A variety of flexible working arrangements are available

Key Responsibilities

• Creation of biomarker analysis datasets from a variety of file and formats from either internal or external labs/vendors. The candidate should be comfortable working with a diverse collection of data files in terms of the type (depending on the assays/platform used to generate the data), data format and size.
• Creation of graphs and tables related to biomarker data primarily for exploratory investigations (hypothesis generation or evaluation) with analysis requirements that may change throughout the life of the project.
• Automation of data creation, graphs, tables and certain Statistical analyses using R scripts and developing R-Shiny apps for delivering automated analysis solutions for end users.
• Act as a subject matter expert and work as a guide within own discipline to investigate new technology as directed.
• Provide technical contribution to complex tasks.
• Participate/Lead the planning and execution of multiple programming activities to deliver all required outputs
• Work as a lead within own discipline to investigate new technology as directed
• Ensure the collection of programs/outputs and issues are adequately managed for programming activities to achieve business outcomes.
• Apply learning from previous activities to result in quicker and more efficient completion of the current task.
• Ability to closely collaborate with major stakeholders in Translational Statistics, GSK's Experimental Medicine Unit, Clinical Programming and Data Management.
• Share learnings with peers and contribute to internal technical discussions/forums.

Why you?

Basic Qualifications

We are looking for professionals with these required skills to achieve our goals:

• BSc or higher in mathematics, statistics, data science, computer science or related discipline.
• Clinical Programming experience, with a thorough understanding of the end to end clinical trial process.

• Recognized expertise in R, SAS programming, and script/macro code development.
• Understanding of other products such as R-Shiny, Python, Power BI, JMP, SAS/GRAPH, SAS Output Delivery System.
• Demonstrated effectiveness in both oral and written communications, able to express ideas and incorporate feedback to produce a completed quality deliverable
• Demonstrated ability to collaborate across functions.

• A solid level of understanding of the pharmaceutical regulatory and publishing processes (e.g. 21 CFR Part 11).
• Demonstrated knowledge of and experience in the application of CDISC data and standards

Preferred Qualifications

If you have the following characteristics, it would be a plus:

• Working knowledge of relevant therapeutic area such as oncology
• Experience leading multiple studies

• Experience with writing and applying Metadata Specifications/Derivations
• Deliver presentations with clarity in internal forums and/or external professional industry meetings
• Able to explain technical approaches to peers and non-technical colleagues/settings

Oncology Data Strategy is committed to supporting the development of novel Oncology therapies in collaboration with Disease Area Strategy. Current GSK Oncology portfolio consists of four key therapy areas: Immuno-Oncology, Oncology Cell & Gene Therapy, Synthetic Lethality, and Tumor Cell Targeting.

US Hiring Locations: Collegeville, PA and Waltham, MA

Canada Hiring Locations : Mississauga

UK Hiring Locations: Stevenage, GSK House

EU Hiring Locations: Netherlands, Belgium

Remote Working: A variety of flexible working arrangements are available

Key Responsibilities

• Application of Programming and Data Science techniques to integrate Historical Trial Data (HTD) of various formats from numerous source platforms and systems.
• Collaborate with our Real World Evidence (RWE) team to incorporate RWD into the Oncology Data Strategy initiatives.
• Contribute to building a robust infrastructure for storage of integrated data and subsequent data lake.
• Invest in developing knowledge in internal and external regulations of data reuse.
• Automation of data creation for delivering analysis solutions for end users.
• Participate/Lead the planning and execution of multiple data strategy programming activities.
• Provide technical contribution to complex tasks.
• Work as a lead within own discipline to investigate new technology as directed.
• Apply learning from previous activities to result in quicker and more efficient completion of the current task.
• Ability to closely collaborate with major stakeholders in Disease Strategy, RWE, Clinical Programming and Statistics, and Data Strategy and Data Engineering.
• Share learnings with peers and contribute to internal technical discussions/forums.

Why you?

Basic Qualifications

We are looking for professionals with these required skills to achieve our goals:

• BSc or higher in mathematics, statistics, data science, computer science or related discipline.
• Clinical Programming experience, with an understanding of the end to end clinical trial process.
• Experience with data pooling and clinical data reuse.
• Experience with RWE databases (for example, FlatIron, Tempus).
• Demonstrated experience in data integration and database design.

• Recognized expertise in R, SAS programming, and script/macro code development.
• Understanding of other products such as R-Shiny, Python, Power BI, JMP, SAS/GRAPH, SAS Output Delivery System.
• Demonstrated effectiveness in both oral and written communications, able to express ideas and incorporate feedback to produce a completed quality deliverable.
• Demonstrated ability to collaborate across functions.
• Experience leading multiple projects.

• Able to explain technical approaches to peers and non-technical colleagues/settings.

• A solid level of understanding of the pharmaceutical regulatory and publishing processes (e.g. 21 CFR Part 11).
• Demonstrated knowledge of and experience in the application of CDISC data and standards.

Preferred Qualifications

If you have the following characteristics, it would be a plus:

• Working knowledge of relevant therapeutic area such as oncology
• Takes responsibility for oversight of others work as assigned by manager

• Experience with writing and applying Metadata Specifications/Derivations
• Deliver presentations with clarity in internal forums and/or external professional industry meetings

Why GSK

At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader inConsumer Health, strengthening our leadership, and transforming our commercial execution. Now, we're making the biggestchanges we've made to our business in over 20 years.We're on track to separate and create two new companies in 2022:New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and geneticsscience; and a new world-leading consumer healthcare company of loved and trusted brands.

With new ambition comes new purpose. For New GSK, this is to unite science, talent and technology to get ahead of diseasetogether - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; andas a new GSK where outstanding people thrive.

Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culturethat isambitious for patients- so we deliver what matters better and faster;accountable for impact- with clear ownership ofgoals and support to succeed; andwhere we do the right thing. So, if you're ready to improve the lives of billions, join us at thisexciting moment in our journey. Join our challenge to get Ahead Together.

What do we do?

GSK is one of the world's foremost pharmaceutical and healthcare companies, with statisticians and programmers working in Research and Development with a global footprint spanning the UK, US, EU, Canada and India. GSK's speed and success in discovering and developing new medicines..... click apply for full job details