Investigator, Genomic Data Scientist

  • GlaxoSmithKline
  • Brentford, Middlesex
  • Sep 21, 2022
Full time Government

Job Description

Site Name: USA - Pennsylvania - Upper Providence, GSK House, Stevenage, USA - Massachusetts - Cambridge
Posted Date: Jun 9 2022

We are seeking a genomic data scientist with a track record of supporting innovative, high-quality research by managing and analyzing large volumes of genetic and genomic data and results.

GSK aims to improve the number of successful late stage clinical trials for innovative medicines, by both identifying and advancing drug targets that have strong evidence of a causal role in disease biology. The Human Genetics team leverages major scientific and technological advances, including investment in biobanks linked to large-scale human health databases, cutting-edge informatics platforms, breakthrough understanding of biological pathways, functional genomics capabilities built upon rapid progress in gene editing, and leading industry-academia partnerships, in order to identify the best targets and to continue evaluation of targets through their life in the pipeline.

The successful candidate will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and key academic collaborators to advance drug discovery and clinical development in multiple disease areas. This research will leverage industry-leading data and compute resources, to address important drug discovery and development challenges, to directly impact GSK's R&D pipeline, and to publish in top scientific journals.

The selected Genomic Data Scientist(s) will:
  • Develop analytics tools and applications to enhance the productivity of scientists within Human Genetics and across the Research organization.
  • Collaborate with Computational Biologists, Statistical Geneticists, and Applied Geneticists to architect scalable, robust, and novel analysis methods.
  • Leverage hybrid cloud environments to scale and/or optimize existing analytical methods.
  • Support development of robust, scalable analysis implementations of high-impact, resource intensive methods, following software development best practices.


Why you?

Basic Qualifications:
  • Bachelors degree
  • 5 or more years experience in genetics, bioinformatics, or related life sciences applications.


Preferred qualifications:
  • Masters degree genetics, bioinformatics, or related life sciences applications 2 years industry experience or Phd in genetics, bioinformatics, or related life sciences applications
  • Experience with collaborative software development.
  • Demonstrated experience implementing analysis of genetic and/or genomic data.
  • Experience working in a distributed data and compute environment ( e.g. Apache Hadoop ecosystem). Experience with Apache SparkTM is a significant advantage
  • Ability to discuss applications of genomic data types and analyses to target identification and prioritization.
  • Experience with data and/or results from large scale genetic association studies
  • Experience working in a HPC environment.
  • Enterprise, industry experience in SQL and either R or Python collaborative software development, with track record of developing production quality software pipelines, applications, or packages/libraries.
  • Familiar with version control ( e.g. git)
  • (e.g. GWAS or PheWAS) or large scale functional genomic data.


Why GSK?

At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader inConsumer Health, strengthening our leadership, and transforming our commercial execution. Now, we're making the biggestchanges we've made to our business in over 20 years.We're on track to separate and create two new companies in 2022:New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and geneticsscience; and a new world-leading consumer healthcare company of loved and trusted brands.

With new ambition comes new purpose. For New GSK, this is to unite science, talent and technology to get ahead of diseasetogether - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; andas a new GSK where outstanding people thrive.

Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culturethat isambitious for patients- so we deliver what matters better and faster;accountable for impact- with clear ownership ofgoals and support to succeed; andwhere we do the right thing. So, if you're ready to improve the lives of billions, join us at thisexciting moment in our journey. Join our challenge to get Ahead Together.

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