Modeling & Simulations Senior Scientist-(Remote) Modeling & Simulations Senior Scientist-(Remote) General Summary: The Modeling & Simulations Senior Scientist at Vertex will lead Modeling & Simulation analyses from planning through reporting and align these analyses with the strategy determined by the modeling program lead. Types of analyses can include modeling and simulation to support evaluation of study design, dose selection, probability of success estimation, portfolio strategy, pediatric extrapolation etc. It is expected that this role will work in close collaboration with colleagues in Clinical Pharmacology, Biostatistics, Research and other colleagues within the R&D organization. Key Duties and Responsibilities: Development and execution of Modeling & Simulation plans and analyses fully integrated with the overall development plans. By using state of the art Modeling & Simulation methodologies, strongly contribute to critical decision making like study design, dose selection, probability of success estimation, etc. Contribute to the continuous improvement in efficiency and effectiveness of our M&S capability by supporting training activities, evaluating and incorporating new M&S tools as appropriate. Perform mechanism based PKPD and population PK and PK/PD analyses, clinical trial simulations, translational modeling (preclinical - clinical) and other model-based analyses in collaboration with other scientists on a regular basis. Contribute M&S expertise to multiple projects, including as the lead representative for specific analyses and evaluate and interpret analysis results. Organizes and participates in departmental functions and represents the department in company-wide, non-scientific initiatives. Integrate modeling into decision making by clearly communicating key results. Knowledge and Skills: Strong experience working in clinical development teams and integrating the use of PK/PD modeling and/or modeling of complex biological systems. A deep understanding of biology, pharmacokinetic and quantitative pharmacology (PKPD) principles. In-depth hands-on skills in population PK and PKPD modeling, mechanistic PKPD modeling, Clinical trial simulations, Disease progression modeling, etc. Advanced skills in the use of NonMem, PsN, R, and similar tools. Excellent verbal and written communication skills. Experience with biologics preferred. Education and Experience: Master's or PhD, with preference in Pharmaceutical sciences, Pharmacometrics, mathematics, statistics, or other quantitative discipline with an emphasis on Pharmacometrics and PKPD modeling. Typically requires the following: PhD and 3 years experience or Master's Degree and 6 years experience in the application of Pharmacometric and other Modeling methodologies in the context of drug research & development in industry, academia or regulatory agencies. Pay Range: $142,400 - $213,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be designated as: 1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at
Feb 18, 2025
Full time
Modeling & Simulations Senior Scientist-(Remote) Modeling & Simulations Senior Scientist-(Remote) General Summary: The Modeling & Simulations Senior Scientist at Vertex will lead Modeling & Simulation analyses from planning through reporting and align these analyses with the strategy determined by the modeling program lead. Types of analyses can include modeling and simulation to support evaluation of study design, dose selection, probability of success estimation, portfolio strategy, pediatric extrapolation etc. It is expected that this role will work in close collaboration with colleagues in Clinical Pharmacology, Biostatistics, Research and other colleagues within the R&D organization. Key Duties and Responsibilities: Development and execution of Modeling & Simulation plans and analyses fully integrated with the overall development plans. By using state of the art Modeling & Simulation methodologies, strongly contribute to critical decision making like study design, dose selection, probability of success estimation, etc. Contribute to the continuous improvement in efficiency and effectiveness of our M&S capability by supporting training activities, evaluating and incorporating new M&S tools as appropriate. Perform mechanism based PKPD and population PK and PK/PD analyses, clinical trial simulations, translational modeling (preclinical - clinical) and other model-based analyses in collaboration with other scientists on a regular basis. Contribute M&S expertise to multiple projects, including as the lead representative for specific analyses and evaluate and interpret analysis results. Organizes and participates in departmental functions and represents the department in company-wide, non-scientific initiatives. Integrate modeling into decision making by clearly communicating key results. Knowledge and Skills: Strong experience working in clinical development teams and integrating the use of PK/PD modeling and/or modeling of complex biological systems. A deep understanding of biology, pharmacokinetic and quantitative pharmacology (PKPD) principles. In-depth hands-on skills in population PK and PKPD modeling, mechanistic PKPD modeling, Clinical trial simulations, Disease progression modeling, etc. Advanced skills in the use of NonMem, PsN, R, and similar tools. Excellent verbal and written communication skills. Experience with biologics preferred. Education and Experience: Master's or PhD, with preference in Pharmaceutical sciences, Pharmacometrics, mathematics, statistics, or other quantitative discipline with an emphasis on Pharmacometrics and PKPD modeling. Typically requires the following: PhD and 3 years experience or Master's Degree and 6 years experience in the application of Pharmacometric and other Modeling methodologies in the context of drug research & development in industry, academia or regulatory agencies. Pay Range: $142,400 - $213,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be designated as: 1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at
Medicinal Chemistry / Chemical Biology Research Scientist Medicinal Chemistry / Chemical Biology Research Scientist Location: Oxford, United Kingdom Job Type: Full time Posted on: Posted 2 Days Ago Job Requisition ID: REQ-24560 General Summary: Vertex Pharmaceuticals has an exciting opportunity at the Oxford site for a Research Scientist to join the Chemical Biology team within Medicinal Chemistry. In this lab-based role, you will be responsible for the design and execution of Chemical Biology experiments to address critical questions for research projects. These could include: designing reagents or tools to evaluate targets; performing experiments to understand compound mechanism of action, target engagement or selectivity; developing novel hit-finding approaches. You will also design and synthesize compounds as part of early drug discovery projects, completing work in a resourceful, timely and self-sufficient manner, to validate hits and advance chemical series towards leads. You will be working as part of an inclusive drug discovery team, in which you will run multiple activities concurrently and adapt to new projects as required. As a member of our team, you will have the opportunity to expand your expertise in drug design and knowledge of the holistic drug discovery process through interactions with colleagues across multiple disciplines in our research labs, with supported training and development materials to help you grow your career within the pharmaceutical company. Key Duties and Responsibilities: Design and perform critical Chemical Biology experiments to assist project teams. Design and synthesize small molecules to support hit validation and hit-to-lead efforts. Design and synthesize chemical probes/tools to support Chemical Biology experiments. Engage, collaborate with, and present data to cross-disciplinary teams from Medicinal Chemistry, Protein Sciences, High Throughput Biology and beyond. Engage proactively with project teams to identify opportunities for Chemical Biology to address critical questions. Maintain a high level of knowledge on the latest advances in Chemical Biology, and apply them to achieve project goals. Contribute to site-wide education in the application of Chemical Biology to drug discovery. Perform other duties as assigned. Knowledge and Skills: Significant practical experience in Chemical Biology relevant to drug discovery (such as, but not limited to, chemical proteomics, target engagement, chemical probe development, novel hit-finding approaches, new chemical modalities, covalent drug discovery). Thorough understanding of the theoretical and practical aspects of synthetic chemistry (synthesis, purification and analytical characterisation). Proven experimental creativity and productivity, with an ability to quickly learn and adopt new concepts and experimental techniques. Effective verbal and written communication with scientists from different disciplines. An understanding of general concepts in medicinal chemistry and other disciplines related to drug discovery (e.g. pharmacology, ADME, drug safety/toxicology). Demonstrate high levels of health and safety awareness, personal integrity and ethics. Education and Experience: PhD (or equivalent degree) in Chemistry, Chemical Biology or related science and 0-3 years of relevant post-doctoral experience, or the equivalent industrial experience. Company Information: Vertex is a global biotechnology company that invests in scientific innovation. This is an onsite role, requiring 5 days per week in our premises. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Program and may be changed at any time. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at
Feb 17, 2025
Full time
Medicinal Chemistry / Chemical Biology Research Scientist Medicinal Chemistry / Chemical Biology Research Scientist Location: Oxford, United Kingdom Job Type: Full time Posted on: Posted 2 Days Ago Job Requisition ID: REQ-24560 General Summary: Vertex Pharmaceuticals has an exciting opportunity at the Oxford site for a Research Scientist to join the Chemical Biology team within Medicinal Chemistry. In this lab-based role, you will be responsible for the design and execution of Chemical Biology experiments to address critical questions for research projects. These could include: designing reagents or tools to evaluate targets; performing experiments to understand compound mechanism of action, target engagement or selectivity; developing novel hit-finding approaches. You will also design and synthesize compounds as part of early drug discovery projects, completing work in a resourceful, timely and self-sufficient manner, to validate hits and advance chemical series towards leads. You will be working as part of an inclusive drug discovery team, in which you will run multiple activities concurrently and adapt to new projects as required. As a member of our team, you will have the opportunity to expand your expertise in drug design and knowledge of the holistic drug discovery process through interactions with colleagues across multiple disciplines in our research labs, with supported training and development materials to help you grow your career within the pharmaceutical company. Key Duties and Responsibilities: Design and perform critical Chemical Biology experiments to assist project teams. Design and synthesize small molecules to support hit validation and hit-to-lead efforts. Design and synthesize chemical probes/tools to support Chemical Biology experiments. Engage, collaborate with, and present data to cross-disciplinary teams from Medicinal Chemistry, Protein Sciences, High Throughput Biology and beyond. Engage proactively with project teams to identify opportunities for Chemical Biology to address critical questions. Maintain a high level of knowledge on the latest advances in Chemical Biology, and apply them to achieve project goals. Contribute to site-wide education in the application of Chemical Biology to drug discovery. Perform other duties as assigned. Knowledge and Skills: Significant practical experience in Chemical Biology relevant to drug discovery (such as, but not limited to, chemical proteomics, target engagement, chemical probe development, novel hit-finding approaches, new chemical modalities, covalent drug discovery). Thorough understanding of the theoretical and practical aspects of synthetic chemistry (synthesis, purification and analytical characterisation). Proven experimental creativity and productivity, with an ability to quickly learn and adopt new concepts and experimental techniques. Effective verbal and written communication with scientists from different disciplines. An understanding of general concepts in medicinal chemistry and other disciplines related to drug discovery (e.g. pharmacology, ADME, drug safety/toxicology). Demonstrate high levels of health and safety awareness, personal integrity and ethics. Education and Experience: PhD (or equivalent degree) in Chemistry, Chemical Biology or related science and 0-3 years of relevant post-doctoral experience, or the equivalent industrial experience. Company Information: Vertex is a global biotechnology company that invests in scientific innovation. This is an onsite role, requiring 5 days per week in our premises. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Program and may be changed at any time. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at
Commercial Distributor & Expansion Markets Director, Middle East and Africa page is loaded Commercial Distributor & Expansion Markets Director, Middle East and Africa Apply locations Paddington, United Kingdom time type Full time posted on Posted Yesterday job requisition id REQ-19314 Job Description The Commercial Distributor & Expansion Markets Director will manage and oversee Vertex's business with third party partners in the Expansion Markets and Assigned region to ensure that all eligible patients gain access to Vertex's medicines in the territory. The incumbent will work closely with Vertex's distributor partners in the region, ensures alignment with international commercial strategy, implements tactical plans and ensures compliance with Vertex's policies, procedures, and expectations. This role will manage in-directly Vertex internal cross-functional teams as well as directly external Distributor Partners in 11 currently assigned countries: GCC countries, Cyprus, Israel, Jordan, South Africa and Turkiye. Future expansion within MEA region is planned and more countries will come under this remit. Position in based in London, 3 days per week- Hybrid mode. Key Responsibilities: Leads the development, management and execution of the Assigned Region / Expansion Markets regional strategic plans in collaboration with Vertex's distributor partners Ensures short and long term revenue opportunities are maximized in order to achieve commercial targets Interacts with local payers, KOLs, patient organizations, and key stakeholders Works cross-functionally within Vertex and locally with the distributor team as necessary to ensure smooth operation of region Enforces a culture of compliance and best practice as well as a commitment to continuously improves efficiency and effectiveness of region operations Oversees planning, analytics and project implementation to ensure successful delivery Ensures effective communication and alignment across the functional matrix regarding the strategy, plan and progress of implementation Leads consulting agencies to conduct detailed analyses in market of interest and deliver high quality, actionable strategic plans. Key Requirements: Experience in Commercial operations in Distributor Markets, in the MEA region Strong and successful background in sales and marketing in Pharma/ Biotech Experience in managing third party commercial relationships and budgets Strong team player with excellent interpersonal, communication, and presentation skills to communicate complex concepts and negotiate with others mainly internally Ability to work cross-functionally as well as autonomously Ability to interact with payors, regulators and various stakeholders Solid understanding of the compliance framework Adept at working in multiple countries/cultures Ability to develop rapport and credibility with key internal and external stakeholders Proven ability to manage complex projects within timeline and budget Ability to plan, adjust, manage and optimize resources Proficiency in developing and overseeing country plans Entrepreneurial with a strong business acumen Ability to travel up to 30%. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at . Similar Jobs (1) Commercial Distributor & Expansion Markets Associate Director, 12 month FTC locations Paddington, United Kingdom time type Full time posted on Posted 30+ Days Ago About Us Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has multiple approved medicines that treat the underlying cause of cystic fibrosis (CF) - a rare, life-threatening genetic disease - and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational small molecule, cell and genetic therapies in other serious diseases where it has deep insight into causal human biology, including sickle cell disease, beta thalassemia, APOL1-mediated kidney disease, pain, type 1 diabetes, alpha-1 antitrypsin deficiency and Duchenne muscular dystrophy. Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia and Latin America. Vertex is consistently recognized as one of the industry's top places to work, including 13 consecutive years on Science magazine's Top Employers list and one of Fortune's Best Workplaces in Biotechnology and Pharmaceuticals and Best Workplaces for Women. For company updates and to learn more about Vertex's history of innovation, visit or follow us on Facebook , Twitter , LinkedIn , YouTube and Instagram . The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people's lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.
Dec 06, 2023
Full time
Commercial Distributor & Expansion Markets Director, Middle East and Africa page is loaded Commercial Distributor & Expansion Markets Director, Middle East and Africa Apply locations Paddington, United Kingdom time type Full time posted on Posted Yesterday job requisition id REQ-19314 Job Description The Commercial Distributor & Expansion Markets Director will manage and oversee Vertex's business with third party partners in the Expansion Markets and Assigned region to ensure that all eligible patients gain access to Vertex's medicines in the territory. The incumbent will work closely with Vertex's distributor partners in the region, ensures alignment with international commercial strategy, implements tactical plans and ensures compliance with Vertex's policies, procedures, and expectations. This role will manage in-directly Vertex internal cross-functional teams as well as directly external Distributor Partners in 11 currently assigned countries: GCC countries, Cyprus, Israel, Jordan, South Africa and Turkiye. Future expansion within MEA region is planned and more countries will come under this remit. Position in based in London, 3 days per week- Hybrid mode. Key Responsibilities: Leads the development, management and execution of the Assigned Region / Expansion Markets regional strategic plans in collaboration with Vertex's distributor partners Ensures short and long term revenue opportunities are maximized in order to achieve commercial targets Interacts with local payers, KOLs, patient organizations, and key stakeholders Works cross-functionally within Vertex and locally with the distributor team as necessary to ensure smooth operation of region Enforces a culture of compliance and best practice as well as a commitment to continuously improves efficiency and effectiveness of region operations Oversees planning, analytics and project implementation to ensure successful delivery Ensures effective communication and alignment across the functional matrix regarding the strategy, plan and progress of implementation Leads consulting agencies to conduct detailed analyses in market of interest and deliver high quality, actionable strategic plans. Key Requirements: Experience in Commercial operations in Distributor Markets, in the MEA region Strong and successful background in sales and marketing in Pharma/ Biotech Experience in managing third party commercial relationships and budgets Strong team player with excellent interpersonal, communication, and presentation skills to communicate complex concepts and negotiate with others mainly internally Ability to work cross-functionally as well as autonomously Ability to interact with payors, regulators and various stakeholders Solid understanding of the compliance framework Adept at working in multiple countries/cultures Ability to develop rapport and credibility with key internal and external stakeholders Proven ability to manage complex projects within timeline and budget Ability to plan, adjust, manage and optimize resources Proficiency in developing and overseeing country plans Entrepreneurial with a strong business acumen Ability to travel up to 30%. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at . Similar Jobs (1) Commercial Distributor & Expansion Markets Associate Director, 12 month FTC locations Paddington, United Kingdom time type Full time posted on Posted 30+ Days Ago About Us Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has multiple approved medicines that treat the underlying cause of cystic fibrosis (CF) - a rare, life-threatening genetic disease - and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational small molecule, cell and genetic therapies in other serious diseases where it has deep insight into causal human biology, including sickle cell disease, beta thalassemia, APOL1-mediated kidney disease, pain, type 1 diabetes, alpha-1 antitrypsin deficiency and Duchenne muscular dystrophy. Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia and Latin America. Vertex is consistently recognized as one of the industry's top places to work, including 13 consecutive years on Science magazine's Top Employers list and one of Fortune's Best Workplaces in Biotechnology and Pharmaceuticals and Best Workplaces for Women. For company updates and to learn more about Vertex's history of innovation, visit or follow us on Facebook , Twitter , LinkedIn , YouTube and Instagram . The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people's lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.
Job DescriptionThe role of Commercial Business Operations Manager is responsible for supporting the Commercial Excellence Lead in coordinating, designing and delivering the commercial excellence activities that enhance customer engagement and facilitate data driven decision making for International Commercial Cell and Gene Therapies. This role will be primarily responsible for overseeing all activities associated to the CRM (customer relationship management) processes for the Cell & Gene Therapy business. Furthermore, this role will have varied responsibilities to support the CGT commercial organization including, customer target setting, implementing field force territory alignments, and strengthening engagement competencies of field based roles.KEY RESPONSIBILITIES:Responsible for prioritizing CRM improvements based on business priorities and user (Field team) feedbackResponsible for developing user stories, acceptance criteria and ordering of product backlogSitting member of the CRM development team, responsible for sprint planning and sprint review discussions.Proactively identifies new improvements to platforms, leveraging CRM subject matter expertiseAligns business priority decisions with IT, cross-functional teams across the Heme launch (including International GMA)Oversees DTE User Acceptance Testing for CRM at each release and the successful rollout of the release to the end usersResponsible for smooth operation of all administrative functions within CGT CRMMaintain effective execution communication to ensure alignment works with other Commercial Business operations managersEDUCATION:Bachelor's degree in communications, marketing, advertising or related discipline with 3 to 6 years related experience - requiredAdvanced degree preferredSKILLS & EXPEREINCE:Minimum Requirements:Extensive sales/marketing commercial operations experience in a dynamic environmentStrong familiarity with CRM processesStrong familiarity with Patient support processesStrong familiarity with Supply chain processesExcellent communication, interpersonal, and leadership skillsExtensive direct experience with pharmaceutical data sourcing, integration, analysis, and reportingAbility and desire to understand the product needs of the future and influence all stakeholders to prioritize themUnderstanding of Web & Mobile technologiesPreferred Qualifications:Attention to detail and committed follow-through in communications to stakeholdersPro-actively identifies issues and solves themAbility to work in a fast-paced, evolving environment; focus on multi-tasking and self-prioritized workloadMarketing experience strongly preferredStrategic mindset with strong focus on executionScientific aptitude and working knowledge of Cell & Gene therapies area (preferable)TravelPosition is based in London Paddington and travel of 20-30% may be required for country visits and training sessions.#LI-JR1Company InformationVertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at .
Dec 08, 2021
Full time
Job DescriptionThe role of Commercial Business Operations Manager is responsible for supporting the Commercial Excellence Lead in coordinating, designing and delivering the commercial excellence activities that enhance customer engagement and facilitate data driven decision making for International Commercial Cell and Gene Therapies. This role will be primarily responsible for overseeing all activities associated to the CRM (customer relationship management) processes for the Cell & Gene Therapy business. Furthermore, this role will have varied responsibilities to support the CGT commercial organization including, customer target setting, implementing field force territory alignments, and strengthening engagement competencies of field based roles.KEY RESPONSIBILITIES:Responsible for prioritizing CRM improvements based on business priorities and user (Field team) feedbackResponsible for developing user stories, acceptance criteria and ordering of product backlogSitting member of the CRM development team, responsible for sprint planning and sprint review discussions.Proactively identifies new improvements to platforms, leveraging CRM subject matter expertiseAligns business priority decisions with IT, cross-functional teams across the Heme launch (including International GMA)Oversees DTE User Acceptance Testing for CRM at each release and the successful rollout of the release to the end usersResponsible for smooth operation of all administrative functions within CGT CRMMaintain effective execution communication to ensure alignment works with other Commercial Business operations managersEDUCATION:Bachelor's degree in communications, marketing, advertising or related discipline with 3 to 6 years related experience - requiredAdvanced degree preferredSKILLS & EXPEREINCE:Minimum Requirements:Extensive sales/marketing commercial operations experience in a dynamic environmentStrong familiarity with CRM processesStrong familiarity with Patient support processesStrong familiarity with Supply chain processesExcellent communication, interpersonal, and leadership skillsExtensive direct experience with pharmaceutical data sourcing, integration, analysis, and reportingAbility and desire to understand the product needs of the future and influence all stakeholders to prioritize themUnderstanding of Web & Mobile technologiesPreferred Qualifications:Attention to detail and committed follow-through in communications to stakeholdersPro-actively identifies issues and solves themAbility to work in a fast-paced, evolving environment; focus on multi-tasking and self-prioritized workloadMarketing experience strongly preferredStrategic mindset with strong focus on executionScientific aptitude and working knowledge of Cell & Gene therapies area (preferable)TravelPosition is based in London Paddington and travel of 20-30% may be required for country visits and training sessions.#LI-JR1Company InformationVertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at .