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Postdoctoral Neuroscientist
NeuroTech X Oxford, Oxfordshire
Postdoctoral Neuroscientist Oxford Full-time, Fixed-term Postdoctoral Neuroscientist Closing Date: 3 June 2025 We are seeking a Postdoctoral Neuroscientist to investigate neuronal mechanisms of memory using state-of-the-art tools available in rodents, including electrophysiology, calcium imaging, optogenetics, and behavioral methods. This project is part of a broader research program aimed at using cross-species studies to understand memory mechanisms in health and disease. The successful candidate will collaborate with team members to design parallel tasks for rodents and humans and apply comparable analytical approaches across species. Insights gained from rodent cell and circuit mechanisms will inform our understanding of human cognition and behavior. The postholder will join the Barron Group at the MRC BNDU and OxCIN, which has a strong reputation in cross-species research on brain circuits involved in memory. The project will leverage the excellent infrastructure, technical expertise, and resources available at these institutions. For more details on the role, responsibilities, and application process, please see the 'Job Description' link on the recruitment system page . This is a full-time position for an initial period of 2 years. Applications must be received by 12:00 midday on 3 June 2025. Please apply via the University of Oxford recruitment system . Interviews will be scheduled as soon as possible thereafter. For more information, click here .
Jul 17, 2025
Full time
Postdoctoral Neuroscientist Oxford Full-time, Fixed-term Postdoctoral Neuroscientist Closing Date: 3 June 2025 We are seeking a Postdoctoral Neuroscientist to investigate neuronal mechanisms of memory using state-of-the-art tools available in rodents, including electrophysiology, calcium imaging, optogenetics, and behavioral methods. This project is part of a broader research program aimed at using cross-species studies to understand memory mechanisms in health and disease. The successful candidate will collaborate with team members to design parallel tasks for rodents and humans and apply comparable analytical approaches across species. Insights gained from rodent cell and circuit mechanisms will inform our understanding of human cognition and behavior. The postholder will join the Barron Group at the MRC BNDU and OxCIN, which has a strong reputation in cross-species research on brain circuits involved in memory. The project will leverage the excellent infrastructure, technical expertise, and resources available at these institutions. For more details on the role, responsibilities, and application process, please see the 'Job Description' link on the recruitment system page . This is a full-time position for an initial period of 2 years. Applications must be received by 12:00 midday on 3 June 2025. Please apply via the University of Oxford recruitment system . Interviews will be scheduled as soon as possible thereafter. For more information, click here .
Postdoc fellow- Bioinformatics & Executable Modelling for Rare Disease Digital Twins
ONE NUCLEUS Cambridge, Cambridgeshire
We are looking for a motivated and talented postdoctoral-level researcher with experience in executable modelling to join a cutting-edge project developing Digital Twins for rare diseases. This is a unique opportunity to work at the intersection of systems biology, AI, and translational research, and to contribute to open science through the Chan Zuckerberg Initiative. Your group Petsalaki Group, in collaboration with Open Targets and BioModels teams. The project Digital Twins are virtual representations of patients that simulate disease progression and treatment response. Rare diseases pose a unique challenge due to limited patient data-especially at the single-cell level-making traditional modelling approaches difficult. This project tackles that challenge by integrating multi-omics and clinical data using hybrid models combining mechanistic, GenAI, and machine learning approaches. You'll contribute to building disease-specific Digital Twins using large-scale single-cell multi-omics datasets, mechanistic simulations, and predictive AI models. Your work will help unlock new insights into disease mechanisms and inform potential treatments, diagnostics, and drug repurposing opportunities. Your role You will develop and apply methods to transform omics data into networks and executable models, collaborating closely with experts across the Petsalaki and Sheriff groups, Open Targets, EMBL-EBI, and the wider rare disease and biocuration community. You will be primarily supervised by the Petsalaki group (Whole cell sigalling) and the Sheriff team (Biomodels). The Petsalaki group develops data driven network inference and modelling approaches from large omics datasets and the Sheriff team leads the development of innovative modelling approaches and maintenance of the Biomodels database. Key responsibilities include: - Generation of phenotype-specific networks from bulk-RNAseq and scRNAseq data from rare disease patients - Building executable models (Boolean, ODE, agent-based or others) from omics data - Collaborating closely with data curators, multi-omics data scientists and AI engineers to integrate and enrich disease datasets, and test and validate models - Applying hybrid modelling approaches to limited data scenarios - Enabling multi-scale and cross-disease modelling for hypothesis generation and therapy discovery - Ensure FAIR principles in your outputs and contribute to the open source community by sharing models (where possible) in BioModels and other repositories - Generation of synthetic data to represent rare disease patients that can be shared You have - A PhD in bioinformatics, physics, or a related data-intensive field - Proficiency in Python (or R), version control, and clean code practices - Experience with omics data analysis and integration - Hands-on expertise in developing and fitting executable models - Strong communication and teamwork skills You may also have - Network inference and analysis experienc - Machine learning experience - Track record of completed research projects (e.g., publications, tools) Benefits and Contract Information - Financial incentives: depending on circumstances, monthly family/marriage allowance of £272, monthly child allowance of £328 per child. Generous stipend reviewed yearly, pension scheme, death benefit, long-term care, accident-at-work and unemployment insurances - Hybrid working arrangements - Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover) - Generous time off: 30 days annual leave per year, in addition to eight bank holidays - Relocation package - Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely) - Family benefits: On-site nursery, child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances - Contract duration: This position is a 2 year fixed term grant limited contract - Salary: Year 1 Stipend at rate of £3,307 (Total package will be dependant on family circumstances) - International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants. - Diversity and inclusion: At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ and individuals from all nationalities. - Job location: This role is based in Hinxton, near Cambridge, UK. You will be required to relocate if you are based overseas and you will receive a generous relocation package to support you. - DORA - EMBL is a signatory of DORA and is committed to hiring and training outstanding research, service, and administrative personnel. Year 1 Stipend - £3,307 per month after tax
Jul 17, 2025
Full time
We are looking for a motivated and talented postdoctoral-level researcher with experience in executable modelling to join a cutting-edge project developing Digital Twins for rare diseases. This is a unique opportunity to work at the intersection of systems biology, AI, and translational research, and to contribute to open science through the Chan Zuckerberg Initiative. Your group Petsalaki Group, in collaboration with Open Targets and BioModels teams. The project Digital Twins are virtual representations of patients that simulate disease progression and treatment response. Rare diseases pose a unique challenge due to limited patient data-especially at the single-cell level-making traditional modelling approaches difficult. This project tackles that challenge by integrating multi-omics and clinical data using hybrid models combining mechanistic, GenAI, and machine learning approaches. You'll contribute to building disease-specific Digital Twins using large-scale single-cell multi-omics datasets, mechanistic simulations, and predictive AI models. Your work will help unlock new insights into disease mechanisms and inform potential treatments, diagnostics, and drug repurposing opportunities. Your role You will develop and apply methods to transform omics data into networks and executable models, collaborating closely with experts across the Petsalaki and Sheriff groups, Open Targets, EMBL-EBI, and the wider rare disease and biocuration community. You will be primarily supervised by the Petsalaki group (Whole cell sigalling) and the Sheriff team (Biomodels). The Petsalaki group develops data driven network inference and modelling approaches from large omics datasets and the Sheriff team leads the development of innovative modelling approaches and maintenance of the Biomodels database. Key responsibilities include: - Generation of phenotype-specific networks from bulk-RNAseq and scRNAseq data from rare disease patients - Building executable models (Boolean, ODE, agent-based or others) from omics data - Collaborating closely with data curators, multi-omics data scientists and AI engineers to integrate and enrich disease datasets, and test and validate models - Applying hybrid modelling approaches to limited data scenarios - Enabling multi-scale and cross-disease modelling for hypothesis generation and therapy discovery - Ensure FAIR principles in your outputs and contribute to the open source community by sharing models (where possible) in BioModels and other repositories - Generation of synthetic data to represent rare disease patients that can be shared You have - A PhD in bioinformatics, physics, or a related data-intensive field - Proficiency in Python (or R), version control, and clean code practices - Experience with omics data analysis and integration - Hands-on expertise in developing and fitting executable models - Strong communication and teamwork skills You may also have - Network inference and analysis experienc - Machine learning experience - Track record of completed research projects (e.g., publications, tools) Benefits and Contract Information - Financial incentives: depending on circumstances, monthly family/marriage allowance of £272, monthly child allowance of £328 per child. Generous stipend reviewed yearly, pension scheme, death benefit, long-term care, accident-at-work and unemployment insurances - Hybrid working arrangements - Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover) - Generous time off: 30 days annual leave per year, in addition to eight bank holidays - Relocation package - Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely) - Family benefits: On-site nursery, child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances - Contract duration: This position is a 2 year fixed term grant limited contract - Salary: Year 1 Stipend at rate of £3,307 (Total package will be dependant on family circumstances) - International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants. - Diversity and inclusion: At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ and individuals from all nationalities. - Job location: This role is based in Hinxton, near Cambridge, UK. You will be required to relocate if you are based overseas and you will receive a generous relocation package to support you. - DORA - EMBL is a signatory of DORA and is committed to hiring and training outstanding research, service, and administrative personnel. Year 1 Stipend - £3,307 per month after tax
Postdoc in Bayesian machine learning, AstraZeneca, Cambridge, UK
The International Society for Bayesian Analysis Cambridge, Cambridgeshire
Postdoc in Bayesian machine learning, AstraZeneca, Cambridge, UK Mar 29, 2018 PREDICTING DRUG TOXICITY WITH BAYESIAN MACHINE LEARNING MODELS We're currently looking for talented scientists to join our innovative academic-style Postdoc. From our centre in Cambridge, UK you'll be in a global pharmaceutical environment, contributing to live projects right from the start. You'll take part in a comprehensive training programme, including a focus on drug discovery and development, given access to our existing Postdoctoral research, and encouraged to pursue your own independent research. It's a newly expanding programme spanning a range of therapeutic areas across a wide range of disciplines. What's more, you'll have the support of a leading academic advisor, who'll provide you with the guidance and knowledge you need to develop your career. You will be part of the Quantitative Biology group and develop comprehensive Bayesian machine learning models for predicting drug toxicity in liver, heart, and other organs. This includes predicting the mechanism as well as the probability of toxicity by incorporating scientific knowledge into the prediction problem, such as known causal relationships and known toxicity mechanisms. Bayesian models will be used to account for uncertainty in the inputs and propagate this uncertainty into the predictions. In addition, you will promote the use of Bayesian methods across safety pharmacology and biology more generally. You are also expected to present your findings at key conferences and in leading publications This project is in collaboration with Prof. Andrew Gelman at Columbia University, and Dr Stanley Lazic at AstraZeneca. Education and Experience Required: - PhD in Statistics, Computer Science, Data Science, or similar - Excellent knowledge of either R or Python (ideally both) - Knowledge of Bayesian statistics - Knowledge of modern Bayesian software such as Stan and PyMC3 - Knowledge of (or an interest in) life sciences This is a 3 year programme. 2 years will be a Fixed Term Contract, with a 1 year extension which will be merit based. The role will be based at Cambridge, UK with a competitive salary on offer. To apply for this position, please follow the link below:
Jul 17, 2025
Full time
Postdoc in Bayesian machine learning, AstraZeneca, Cambridge, UK Mar 29, 2018 PREDICTING DRUG TOXICITY WITH BAYESIAN MACHINE LEARNING MODELS We're currently looking for talented scientists to join our innovative academic-style Postdoc. From our centre in Cambridge, UK you'll be in a global pharmaceutical environment, contributing to live projects right from the start. You'll take part in a comprehensive training programme, including a focus on drug discovery and development, given access to our existing Postdoctoral research, and encouraged to pursue your own independent research. It's a newly expanding programme spanning a range of therapeutic areas across a wide range of disciplines. What's more, you'll have the support of a leading academic advisor, who'll provide you with the guidance and knowledge you need to develop your career. You will be part of the Quantitative Biology group and develop comprehensive Bayesian machine learning models for predicting drug toxicity in liver, heart, and other organs. This includes predicting the mechanism as well as the probability of toxicity by incorporating scientific knowledge into the prediction problem, such as known causal relationships and known toxicity mechanisms. Bayesian models will be used to account for uncertainty in the inputs and propagate this uncertainty into the predictions. In addition, you will promote the use of Bayesian methods across safety pharmacology and biology more generally. You are also expected to present your findings at key conferences and in leading publications This project is in collaboration with Prof. Andrew Gelman at Columbia University, and Dr Stanley Lazic at AstraZeneca. Education and Experience Required: - PhD in Statistics, Computer Science, Data Science, or similar - Excellent knowledge of either R or Python (ideally both) - Knowledge of Bayesian statistics - Knowledge of modern Bayesian software such as Stan and PyMC3 - Knowledge of (or an interest in) life sciences This is a 3 year programme. 2 years will be a Fixed Term Contract, with a 1 year extension which will be merit based. The role will be based at Cambridge, UK with a competitive salary on offer. To apply for this position, please follow the link below:
Anthony Nolan
Postdoctoral Research Scientist Research Anthony Nolan Research Institute
Anthony Nolan
We're Anthony Nolan. We're here to uncover the answers inside us. Answers for people with blood cancer and blood disorders. Answers that will not only improve lives today but save them tomorrow. By uniting people and science, we're growing our world-leading stem cell register, so everyone who needs a transplant, can find their lifesaving match. We're currently giving four people a day another chance to live. Driven by patients, backed by stem cell donors, and powered by science, we won't stop until we've unlocked the cures, treatments and transplants that will transform the future for more patients. And together, we can reach the remarkable day where every patient who needs us can not only survive, but thrive. If you're inspired by this vision, and feel you have the skills and experience we need to help achieve it, we'd love you to join our lifesaving team. We are looking for a Postdoctoral Research Scientist to join our Immunotherapy team Title: Postdoctoral Research Scientist Salary: £39, 900 - £46,000per annum (depending on experience) Contract: 3 years -fixed term Hours: 35 per week (standard Anthony Nolan working hours) Location: Royal Free Campus, Hampstead, London As part of the Immunotherapy group, you will be involved in multiple translational and basic science research projects, which aim to improve the outcomes of haematopoietic cell transplant. The main project seeks to develop a cell therapy product, based on NK cells, to treat relapse, the main cause of mortality following transplant. What's in it for you? A competitive salary 27 days annual leave (pro rata), pension scheme, childcare vouchers, access to counselling via a 24-hour Employee Assistance Programme A stimulating work environment full of opportunities to learn and develop Life Assurance of four times annual salary Travel season ticket loan, Cycle to work Scheme And more! (further details on our Life at Anthony Nolan page) Please check out the full job description here , and you can read more about what to expect on the Our recruitment process page. Release your remarkable, join our team and give someone another chance to live. Anthony Nolan is a Disability Confident Committed and Living Wage accredited employer. All applicants must be able to demonstrate the right to work in the UK.
Jul 17, 2025
Full time
We're Anthony Nolan. We're here to uncover the answers inside us. Answers for people with blood cancer and blood disorders. Answers that will not only improve lives today but save them tomorrow. By uniting people and science, we're growing our world-leading stem cell register, so everyone who needs a transplant, can find their lifesaving match. We're currently giving four people a day another chance to live. Driven by patients, backed by stem cell donors, and powered by science, we won't stop until we've unlocked the cures, treatments and transplants that will transform the future for more patients. And together, we can reach the remarkable day where every patient who needs us can not only survive, but thrive. If you're inspired by this vision, and feel you have the skills and experience we need to help achieve it, we'd love you to join our lifesaving team. We are looking for a Postdoctoral Research Scientist to join our Immunotherapy team Title: Postdoctoral Research Scientist Salary: £39, 900 - £46,000per annum (depending on experience) Contract: 3 years -fixed term Hours: 35 per week (standard Anthony Nolan working hours) Location: Royal Free Campus, Hampstead, London As part of the Immunotherapy group, you will be involved in multiple translational and basic science research projects, which aim to improve the outcomes of haematopoietic cell transplant. The main project seeks to develop a cell therapy product, based on NK cells, to treat relapse, the main cause of mortality following transplant. What's in it for you? A competitive salary 27 days annual leave (pro rata), pension scheme, childcare vouchers, access to counselling via a 24-hour Employee Assistance Programme A stimulating work environment full of opportunities to learn and develop Life Assurance of four times annual salary Travel season ticket loan, Cycle to work Scheme And more! (further details on our Life at Anthony Nolan page) Please check out the full job description here , and you can read more about what to expect on the Our recruitment process page. Release your remarkable, join our team and give someone another chance to live. Anthony Nolan is a Disability Confident Committed and Living Wage accredited employer. All applicants must be able to demonstrate the right to work in the UK.
Postdoctoral Researcher (Foraminifera Geochemist)
Geological Society of London
Postdoctoral Researcher (Foraminifera Geochemist) Postdoc Researcher Scroll down to read more: Rehemat Job title: Postdoctoral Researcher - Foraminifera Geochemist What does a Foraminifera Geochemist do? I am a hybrid micropalaeontologist and geochemist. A micropalaeontologist studies microscopic fossils, and a geochemist analyses the chemistry of geological materials. I use the chemistry of fossil species of foraminifera, a type of plankton with a calcium carbonate skeleton, to understand more about their ecologies and climate millions of years ago (palaeoclimatology). Different chemical elements can help me understand how hot the oceans were, whether some species of plankton lived closer to the surface of the ocean or further down in the water column, and even how much ice there was on land! I wash sediment samples, identify the plankton hiding inside, then analyse them for their chemistry and try to understand the data they produce. What formal qualifications and previous work experience did you need to get your job? When I was a teenager I did some work experience at the Natural History Museum, London and The Royal Geographical Society. Having had a super positive introduction to Earth Sciences through these experiences, I decided to do an undergraduate MSci degree in Geoscience at Royal Holloway (University of London). During my undergraduate degree I did several internships. I interned at a structural geology company, biostratigraphy company and a summer research internship focused around foraminifera and palaeoclimatology working with a PhD student in Kiel, Germany. I also volunteered at the Natural History Museum throughout the final years of my undergraduate degree. These last two experiences made me realise I could combine my love of geochemistry and ocean sciences, and I subsequently decided to do a PhD at University College London. What other skills or characteristics do you need in your job? Always be curious Always be persistent Understand how to communicate your science to non-specialists in an enthusiastic way Have good attention to detail for taxonomy Know the importance of collaboration and networking. You never know when your mass spectrometer will break and you will need to contact another lab to use their instrument! What sort of organisation do you work for? Where else could you work as a Foraminifera Geochemist? I work at a university, but those with my background can also work in many different sectors, including the oil industry (as a biostratigrapher, using foraminfera to date rock formations), analytical instrument companies, science policy and publishers. Science communication is also popular, but this is definitely applicable as a career path across geological facets! Working in the third sector (i.e. with charities and NGOs) within Trusts and Foundations/Major Donor Fundraising is also possible, because all researchers have the ability to network, collaborate, project manage, build relationships with others and write grant applications concisely. What do you enjoy about your job? Foraminifera are beautiful and each time I have microscope work to do it is a joy to see them. I enjoy being able to talk with young people about what I do. It's really rewarding to inspire the generation to go into STEM and sometimes even helps me figure out what my data mean! I like how no two days are the same. Sometimes I'm doing labwork, sometimes I am writing and sometimes I am reading about all the new and exciting science that is going on in the field. Whilst the dynamic-ness of being a researcher can sometimes be challenging in terms of work/life balance, my lab group are really supportive and I'm so lucky to be working with them. What opportunities do you have to develop your skills in your job? In my postdoc and PhD, I went to summer schools and workshops focused around Earth and ocean sciences in some really cool places, including Israel and Italy. I also went to international conferences to present my data, and regularly did outreach presentations to young people. I also had the opportunity to attend workshops focused around science policy and diversity and inclusion in the geosciences. It's definitely important to go to a variety of professional development courses, because if researchers decide academia is not for them at any point in their career, they have evidence that they have some training for other sectors. What advice or extra information do you wish you'd had before starting this career? Writing is a big part of being an academic, and it can be really challenging. But the first draft of anything will never be perfect, and words down on paper is much better than no words at all! No two days are the same when you are a geoscientist. Even if you don't pass an exam early on during undergrad, this doesn't define who you are. There are always more opportunities to do better next time. When you say you're a geologist, sometimes people will be surprised by this. But it's not weird to like rocks and fossils. Geologists and ocean scientists study some of the oldest things on the Earth, go to some absolutely amazing places (for work!), and unravel the stories of the world around them.
Jul 16, 2025
Full time
Postdoctoral Researcher (Foraminifera Geochemist) Postdoc Researcher Scroll down to read more: Rehemat Job title: Postdoctoral Researcher - Foraminifera Geochemist What does a Foraminifera Geochemist do? I am a hybrid micropalaeontologist and geochemist. A micropalaeontologist studies microscopic fossils, and a geochemist analyses the chemistry of geological materials. I use the chemistry of fossil species of foraminifera, a type of plankton with a calcium carbonate skeleton, to understand more about their ecologies and climate millions of years ago (palaeoclimatology). Different chemical elements can help me understand how hot the oceans were, whether some species of plankton lived closer to the surface of the ocean or further down in the water column, and even how much ice there was on land! I wash sediment samples, identify the plankton hiding inside, then analyse them for their chemistry and try to understand the data they produce. What formal qualifications and previous work experience did you need to get your job? When I was a teenager I did some work experience at the Natural History Museum, London and The Royal Geographical Society. Having had a super positive introduction to Earth Sciences through these experiences, I decided to do an undergraduate MSci degree in Geoscience at Royal Holloway (University of London). During my undergraduate degree I did several internships. I interned at a structural geology company, biostratigraphy company and a summer research internship focused around foraminifera and palaeoclimatology working with a PhD student in Kiel, Germany. I also volunteered at the Natural History Museum throughout the final years of my undergraduate degree. These last two experiences made me realise I could combine my love of geochemistry and ocean sciences, and I subsequently decided to do a PhD at University College London. What other skills or characteristics do you need in your job? Always be curious Always be persistent Understand how to communicate your science to non-specialists in an enthusiastic way Have good attention to detail for taxonomy Know the importance of collaboration and networking. You never know when your mass spectrometer will break and you will need to contact another lab to use their instrument! What sort of organisation do you work for? Where else could you work as a Foraminifera Geochemist? I work at a university, but those with my background can also work in many different sectors, including the oil industry (as a biostratigrapher, using foraminfera to date rock formations), analytical instrument companies, science policy and publishers. Science communication is also popular, but this is definitely applicable as a career path across geological facets! Working in the third sector (i.e. with charities and NGOs) within Trusts and Foundations/Major Donor Fundraising is also possible, because all researchers have the ability to network, collaborate, project manage, build relationships with others and write grant applications concisely. What do you enjoy about your job? Foraminifera are beautiful and each time I have microscope work to do it is a joy to see them. I enjoy being able to talk with young people about what I do. It's really rewarding to inspire the generation to go into STEM and sometimes even helps me figure out what my data mean! I like how no two days are the same. Sometimes I'm doing labwork, sometimes I am writing and sometimes I am reading about all the new and exciting science that is going on in the field. Whilst the dynamic-ness of being a researcher can sometimes be challenging in terms of work/life balance, my lab group are really supportive and I'm so lucky to be working with them. What opportunities do you have to develop your skills in your job? In my postdoc and PhD, I went to summer schools and workshops focused around Earth and ocean sciences in some really cool places, including Israel and Italy. I also went to international conferences to present my data, and regularly did outreach presentations to young people. I also had the opportunity to attend workshops focused around science policy and diversity and inclusion in the geosciences. It's definitely important to go to a variety of professional development courses, because if researchers decide academia is not for them at any point in their career, they have evidence that they have some training for other sectors. What advice or extra information do you wish you'd had before starting this career? Writing is a big part of being an academic, and it can be really challenging. But the first draft of anything will never be perfect, and words down on paper is much better than no words at all! No two days are the same when you are a geoscientist. Even if you don't pass an exam early on during undergrad, this doesn't define who you are. There are always more opportunities to do better next time. When you say you're a geologist, sometimes people will be surprised by this. But it's not weird to like rocks and fossils. Geologists and ocean scientists study some of the oldest things on the Earth, go to some absolutely amazing places (for work!), and unravel the stories of the world around them.
Postdoctoral Researcher
The John Innes Centre Norwich, Norfolk
Hours per week 37 Project Title Computational Modelling of Epigenetic Dynamics Expected/Ideal Start Date 01 Oct 2025 Months Duration 36 Job Description Main Purpose of the Job Applications are invited for a Postdoctoral Researcher to join the group of Prof Martin Howard in the Department of Computational and Systems Biology at the John Innes Centre, Norwich, UK. The main purpose of the position is to develop computational models of epigenetic dynamics in the Polycomb system, collaborating with the experimental group of Prof Rob Klose (Oxford). Key Relationships Other members of the Howard group, other groups within Computational and Systems Biology at JIC, and other external experimental groups, particularly that of Prof. Rob Klose in the Dept of Biochemistry, Oxford University. Main Activities & Responsibilities Percentage Identify, plan, carry out and modify modelling to meet the objectives of the project 50 Prepare results, reports and manuscripts for publication in leading scientific journals and other relevant media 20 Disseminate research findings through presentations to various audiences at internal, national and international meetings 10 Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements 5 Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence 5 Continually strive for excellence, seeking out and acting on feedback and relevant learning and development opportunities 5 As agreed with the line manager, any other duties commensurate with the nature of the post, for example, contributing to the work of Institute committees 5 Person Profile Education & Qualifications Requirement Importance PhD (full award or expected within 6 months) in Theoretical Physics/Bio-Mathematics/Computational Biology Essential BSc or equivalent in a relevant scientific field Essential Specialist Knowledge & Skills Requirement Importance Ability to apply techniques from theoretical physics/applied mathematics to biological problems Essential Strong interest in biological problems Essential Computer programming experience (e.g. use of computational tools such as MatLab) Desirable Requirement Importance Demonstrable scientific success, with track-record of publications and presentations Essential Prior experience in biological modelling Desirable Interpersonal & Communication Skills Requirement Importance Self-motivated, creative and intellectually independent Essential Good verbal and written communication skills, facilitating interaction with experimentalists Essential Ability to collaborate with internal and external stakeholders Essential Excellent time management and organisational skills Essential Good interpersonal skills, with the ability to work well as part of a team Essential Additional Requirements Requirement Importance Available to travel to international meetings and for short visits to collaborating laboratories Essential Willingness to work outside standard working hours when required Essential Attention to detail Essential Promotes equality and values diversity Essential Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work Essential Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute Essential Who We Are The John Innes Centre is an independent, international centre of excellence in plant and microbial genetics, carrying out fundamental and strategic research, to train scientists and making our findings available to society. Our research makes use of a wide range of disciplines in the biological and chemical sciences including; cell biology, biochemistry, chemistry, genetics and molecular biology. We pride ourselves on being a welcoming and inclusive working environment for all. We have a diverse and multicultural scientific community and thrive on our European and international links, appointing staff from across the world. Any candidate who would like further information on current or anticipated immigration requirements can contact the HR Team on (0) or . We are proud to hold a prestigious Athena SWAN Gold award , recognising the impact of our work in promoting gender equality in science. We are also a proud member of the Stonewall Diversity Champion's programme , a founding signatory of the Tecnician Commitment and, as a Disability Confident employer, guarantee to offer an interview to all disabled applicants who meet the essential criteria for the post. The John Innes Centre is a registered charity (No. 223852), limited by guarantee (registered in England No. 511709). Department Computational and Systems Biology The Department of Computational and Systems Biology conducts world-leading research across a broad range of the biological sciences, with a special focus on spatial problems in plant and microbial research. Particular strengths of the department include mathematical and statistical modelling of the physical mechanisms underlying biological pattern formation, transport dynamics, epigenetic processes, size control, biomechanics and gene network dynamics. In addition, the department has strong bioinformatics that underpins the research of the institute through training, software development and statistical analysis. While much of the research is carried out in close collaboration with world-leading experimental groups within the John Innes Centre, we also have strong international collaborations with experimentalists and theoreticians worldwide. The Howard group combines simple, predictive mathematical and biophysical modelling with long-lasting experimental collaborations to dissect biological mechanisms too complex to unravel by experiments alone. In many cases we are able to rationalise complex biological dynamics into simple underlying mechanisms, with few components and interactions. Our approach is highly interdisciplinary and relies heavily on the techniques of statistical physics and applied mathematics, as well as on close collaboration with experimental groups. This truly interdisciplinary approach allows us to get to the heart of biological mechanisms more speedily. At present there are two main foci in the group: probing how epigenetic memory states are set up and then stably maintained, and understanding patterning dynamics in sub-cellular biological systems. For epigenetics, we work on both histone modification memory systems, including the Polycomb system, as well as on DNA methylation. For patterning, the main application at present is to the dynamics of crossover positioning in meiosis. The group collaborates with a wide range of experimentalists in systems ranging from plants to mammalian stem cells. Currently there are three Postdoctoral Researchers in the group. Postdoctoral Researcher Salary: £36,720 - £39,750 per annum depending on qualifications and experience. Contract: 36 months, full-time Location: John Innes Centre, Norwich, UK. Closing date: 2 August 2025 Reference: An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology. About the John Innes Centre: The John Innes Centre is an independent, international centre of excellence in plant and microbial sciences. We nurture a creative, curiosity-led approach to answering fundamental questions in bioscience, and translate that knowledge into societal benefits. Our strategic vision, Healthy Plants, Healthy People, Healthy Planet , sets out our ambitious long-term goals for the game changing impact of our science globally. Our employees enjoy access to state-of-the-art technology and a diverse range of specialist training opportunities, including support for leadership and management. Click here to find out more about working at the John Innes Centre. About the Howard Group: The Howard group combines simple, predictive mathematical and biophysical modelling with long-lasting experimental collaborations to dissect biological mechanisms too complex to unravel by experiments alone. In many cases we are able to rationalise complex biological dynamics into simple underlying mechanisms, with few components and interactions. Our approach is highly interdisciplinary and relies heavily on the techniques of statistical physics and applied mathematics, as well as on close collaboration with experimental groups. At present there are two main research areas in the group: probing how epigenetic memory states are set up and then stably maintained, and understanding patterning dynamics in sub-cellular biological systems. For epigenetics, we work on both histone modification memory systems, particularly the Polycomb silencing system, as well as on DNA methylation. For patterning, the main application at present is to the dynamics of crossover positioning in meiosis. The group regularly publishes in the most prominent multidisciplinary journals, with recent papers in Nature, Science, Cell Systems, eLife, Molecular Cell and PNAS. Several previous members of the Howard group now hold independent faculty positions of their own, including in Warwick, Glasgow, Sydney, Amsterdam and Munich. The role: . click apply for full job details
Jul 16, 2025
Full time
Hours per week 37 Project Title Computational Modelling of Epigenetic Dynamics Expected/Ideal Start Date 01 Oct 2025 Months Duration 36 Job Description Main Purpose of the Job Applications are invited for a Postdoctoral Researcher to join the group of Prof Martin Howard in the Department of Computational and Systems Biology at the John Innes Centre, Norwich, UK. The main purpose of the position is to develop computational models of epigenetic dynamics in the Polycomb system, collaborating with the experimental group of Prof Rob Klose (Oxford). Key Relationships Other members of the Howard group, other groups within Computational and Systems Biology at JIC, and other external experimental groups, particularly that of Prof. Rob Klose in the Dept of Biochemistry, Oxford University. Main Activities & Responsibilities Percentage Identify, plan, carry out and modify modelling to meet the objectives of the project 50 Prepare results, reports and manuscripts for publication in leading scientific journals and other relevant media 20 Disseminate research findings through presentations to various audiences at internal, national and international meetings 10 Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements 5 Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence 5 Continually strive for excellence, seeking out and acting on feedback and relevant learning and development opportunities 5 As agreed with the line manager, any other duties commensurate with the nature of the post, for example, contributing to the work of Institute committees 5 Person Profile Education & Qualifications Requirement Importance PhD (full award or expected within 6 months) in Theoretical Physics/Bio-Mathematics/Computational Biology Essential BSc or equivalent in a relevant scientific field Essential Specialist Knowledge & Skills Requirement Importance Ability to apply techniques from theoretical physics/applied mathematics to biological problems Essential Strong interest in biological problems Essential Computer programming experience (e.g. use of computational tools such as MatLab) Desirable Requirement Importance Demonstrable scientific success, with track-record of publications and presentations Essential Prior experience in biological modelling Desirable Interpersonal & Communication Skills Requirement Importance Self-motivated, creative and intellectually independent Essential Good verbal and written communication skills, facilitating interaction with experimentalists Essential Ability to collaborate with internal and external stakeholders Essential Excellent time management and organisational skills Essential Good interpersonal skills, with the ability to work well as part of a team Essential Additional Requirements Requirement Importance Available to travel to international meetings and for short visits to collaborating laboratories Essential Willingness to work outside standard working hours when required Essential Attention to detail Essential Promotes equality and values diversity Essential Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work Essential Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute Essential Who We Are The John Innes Centre is an independent, international centre of excellence in plant and microbial genetics, carrying out fundamental and strategic research, to train scientists and making our findings available to society. Our research makes use of a wide range of disciplines in the biological and chemical sciences including; cell biology, biochemistry, chemistry, genetics and molecular biology. We pride ourselves on being a welcoming and inclusive working environment for all. We have a diverse and multicultural scientific community and thrive on our European and international links, appointing staff from across the world. Any candidate who would like further information on current or anticipated immigration requirements can contact the HR Team on (0) or . We are proud to hold a prestigious Athena SWAN Gold award , recognising the impact of our work in promoting gender equality in science. We are also a proud member of the Stonewall Diversity Champion's programme , a founding signatory of the Tecnician Commitment and, as a Disability Confident employer, guarantee to offer an interview to all disabled applicants who meet the essential criteria for the post. The John Innes Centre is a registered charity (No. 223852), limited by guarantee (registered in England No. 511709). Department Computational and Systems Biology The Department of Computational and Systems Biology conducts world-leading research across a broad range of the biological sciences, with a special focus on spatial problems in plant and microbial research. Particular strengths of the department include mathematical and statistical modelling of the physical mechanisms underlying biological pattern formation, transport dynamics, epigenetic processes, size control, biomechanics and gene network dynamics. In addition, the department has strong bioinformatics that underpins the research of the institute through training, software development and statistical analysis. While much of the research is carried out in close collaboration with world-leading experimental groups within the John Innes Centre, we also have strong international collaborations with experimentalists and theoreticians worldwide. The Howard group combines simple, predictive mathematical and biophysical modelling with long-lasting experimental collaborations to dissect biological mechanisms too complex to unravel by experiments alone. In many cases we are able to rationalise complex biological dynamics into simple underlying mechanisms, with few components and interactions. Our approach is highly interdisciplinary and relies heavily on the techniques of statistical physics and applied mathematics, as well as on close collaboration with experimental groups. This truly interdisciplinary approach allows us to get to the heart of biological mechanisms more speedily. At present there are two main foci in the group: probing how epigenetic memory states are set up and then stably maintained, and understanding patterning dynamics in sub-cellular biological systems. For epigenetics, we work on both histone modification memory systems, including the Polycomb system, as well as on DNA methylation. For patterning, the main application at present is to the dynamics of crossover positioning in meiosis. The group collaborates with a wide range of experimentalists in systems ranging from plants to mammalian stem cells. Currently there are three Postdoctoral Researchers in the group. Postdoctoral Researcher Salary: £36,720 - £39,750 per annum depending on qualifications and experience. Contract: 36 months, full-time Location: John Innes Centre, Norwich, UK. Closing date: 2 August 2025 Reference: An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology. About the John Innes Centre: The John Innes Centre is an independent, international centre of excellence in plant and microbial sciences. We nurture a creative, curiosity-led approach to answering fundamental questions in bioscience, and translate that knowledge into societal benefits. Our strategic vision, Healthy Plants, Healthy People, Healthy Planet , sets out our ambitious long-term goals for the game changing impact of our science globally. Our employees enjoy access to state-of-the-art technology and a diverse range of specialist training opportunities, including support for leadership and management. Click here to find out more about working at the John Innes Centre. About the Howard Group: The Howard group combines simple, predictive mathematical and biophysical modelling with long-lasting experimental collaborations to dissect biological mechanisms too complex to unravel by experiments alone. In many cases we are able to rationalise complex biological dynamics into simple underlying mechanisms, with few components and interactions. Our approach is highly interdisciplinary and relies heavily on the techniques of statistical physics and applied mathematics, as well as on close collaboration with experimental groups. At present there are two main research areas in the group: probing how epigenetic memory states are set up and then stably maintained, and understanding patterning dynamics in sub-cellular biological systems. For epigenetics, we work on both histone modification memory systems, particularly the Polycomb silencing system, as well as on DNA methylation. For patterning, the main application at present is to the dynamics of crossover positioning in meiosis. The group regularly publishes in the most prominent multidisciplinary journals, with recent papers in Nature, Science, Cell Systems, eLife, Molecular Cell and PNAS. Several previous members of the Howard group now hold independent faculty positions of their own, including in Warwick, Glasgow, Sydney, Amsterdam and Munich. The role: . click apply for full job details
Amazon
Postdoctoral Scientist, Rufus Features Science
Amazon
Job ID: Amazon Development Centre (London) Limited Amazon is looking for talented Postdoctoral Scientists to join our team for a one-year, full-time research position. Postdoctoral Scientists will innovate in key areas of machine learning, natural language processing, computer vision, automated reasoning, robotics, or quantum technologies. As part of the Rufus Features Science team in London, the postdoc will work on shaping the future of AI-driven shopping experiences at Amazon. In particular, the project focuses on conversational search in shopping, developing next-generation conversational search systems in the shopping domain that seamlessly bridge natural shopping dialogues with precise product retrieval and recommendation. Key challenges include developing new methods for grounding conversational context in product attribute space, designing efficient retrieval mechanisms that can handle both structured product metadata and unstructured conversational context, and creating evaluation frameworks that capture both conversation quality and search relevance. The project will extend beyond traditional conversational search paradigms by integrating agentic frameworks that can proactively identify, clarify, and refine user needs through strategic dialogue management, while simultaneously orchestrating multiple specialized retrieval agents for different aspects of the shopping journey (e.g., attribute extraction, price comparison, review analysis, and specification matching). We experiment and innovate relentlessly. Science is core in our offering to shoppers, advertisers and customers. Our scientists apply machine learning, optimization, causal modeling and game theory at scale to enhance the customer experience, help advertisers reach relevant audiences, and support brand building. We are seeking talented scientists to invent cutting-edge techniques in a variety of areas and innovate on behalf of shoppers, advertisers, and customers. In this role you will: Lead research projects in conversational search and retrieval-augmented systems Develop novel architectures combining dialogue management with product search Design and implement evaluation frameworks for agentic conversational shopping systems Publish research findings in top-tier conferences and journals Mentor junior researchers and contribute to the team's scientific direction BASIC QUALIFICATIONS PhD in Computer Science, Machine Learning, Information Retrieval or related field Strong publication record in NLP, Information Retrieval, or Conversational AI Experience with large language models and retrieval-augmented generation Research background in conversational systems or dialogue management Experience with modern deep learning frameworks (PyTorch, TensorFlow) Excellent written and verbal communication skills PREFERRED QUALIFICATIONS Knowledge of multi-agent systems and tool-use frameworks Experience with e-commerce or shopping domain applications Publications at top venues (ACL, NeurIPS, SIGIR, AAAI, etc.) Amazon is an equal opportunities employer. We believe passionately that employing a diverse workforce is central to our success. We make recruiting decisions based on your experience and skills. We value your passion to discover, invent, simplify and build. Protecting your privacy and the security of your data is a longstanding top priority for Amazon. Please consult our Privacy Notice ( ) to know more about how we collect, use and transfer the personal data of our candidates. Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner. Posted: May 16, 2025 (Updated 2 days ago) Posted: May 19, 2025 (Updated 4 days ago) Posted: April 16, 2025 (Updated 8 days ago) Posted: April 11, 2025 (Updated 8 days ago) Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.
Jul 16, 2025
Full time
Job ID: Amazon Development Centre (London) Limited Amazon is looking for talented Postdoctoral Scientists to join our team for a one-year, full-time research position. Postdoctoral Scientists will innovate in key areas of machine learning, natural language processing, computer vision, automated reasoning, robotics, or quantum technologies. As part of the Rufus Features Science team in London, the postdoc will work on shaping the future of AI-driven shopping experiences at Amazon. In particular, the project focuses on conversational search in shopping, developing next-generation conversational search systems in the shopping domain that seamlessly bridge natural shopping dialogues with precise product retrieval and recommendation. Key challenges include developing new methods for grounding conversational context in product attribute space, designing efficient retrieval mechanisms that can handle both structured product metadata and unstructured conversational context, and creating evaluation frameworks that capture both conversation quality and search relevance. The project will extend beyond traditional conversational search paradigms by integrating agentic frameworks that can proactively identify, clarify, and refine user needs through strategic dialogue management, while simultaneously orchestrating multiple specialized retrieval agents for different aspects of the shopping journey (e.g., attribute extraction, price comparison, review analysis, and specification matching). We experiment and innovate relentlessly. Science is core in our offering to shoppers, advertisers and customers. Our scientists apply machine learning, optimization, causal modeling and game theory at scale to enhance the customer experience, help advertisers reach relevant audiences, and support brand building. We are seeking talented scientists to invent cutting-edge techniques in a variety of areas and innovate on behalf of shoppers, advertisers, and customers. In this role you will: Lead research projects in conversational search and retrieval-augmented systems Develop novel architectures combining dialogue management with product search Design and implement evaluation frameworks for agentic conversational shopping systems Publish research findings in top-tier conferences and journals Mentor junior researchers and contribute to the team's scientific direction BASIC QUALIFICATIONS PhD in Computer Science, Machine Learning, Information Retrieval or related field Strong publication record in NLP, Information Retrieval, or Conversational AI Experience with large language models and retrieval-augmented generation Research background in conversational systems or dialogue management Experience with modern deep learning frameworks (PyTorch, TensorFlow) Excellent written and verbal communication skills PREFERRED QUALIFICATIONS Knowledge of multi-agent systems and tool-use frameworks Experience with e-commerce or shopping domain applications Publications at top venues (ACL, NeurIPS, SIGIR, AAAI, etc.) Amazon is an equal opportunities employer. We believe passionately that employing a diverse workforce is central to our success. We make recruiting decisions based on your experience and skills. We value your passion to discover, invent, simplify and build. Protecting your privacy and the security of your data is a longstanding top priority for Amazon. Please consult our Privacy Notice ( ) to know more about how we collect, use and transfer the personal data of our candidates. Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner. Posted: May 16, 2025 (Updated 2 days ago) Posted: May 19, 2025 (Updated 4 days ago) Posted: April 16, 2025 (Updated 8 days ago) Posted: April 11, 2025 (Updated 8 days ago) Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.
Taylorollinson Ltd
Senior Scientist - PET Imaging
Taylorollinson Ltd
Contract - Initially a 2 year fixed term contract - onsite. Salary - £40,000 - £45,000 depending on experience. Our client are a scientifically passionate company who lead extensive collaborations and offer services to the Drug Discovery and Disease Research sectors. They collaborate with lead researchers and organisations to enhance the understanding of immunological, oncological, neurological and other disease areas. Based in Alderley Park, they are offering an exciting opportunity for an enthusiastic and hard-working individual to join their in vivo imaging team as a Senior Scientist. If you are looking to work on exciting translational in vivo imaging projects and want to further your career, then this could be the opportunity you have been waiting for. The Role This is a role for experienced Imaging Scientists who hold a PhD (or Master's) in a biologically focused discipline, with additional postdoctoral or industry experience. As a Senior Imaging Scientist, you will be responsible for: Designing and running mouse + rodent PET / in vivo imaging studies for a range of purposes including biodistribution, pharmacokinetics (PK) and cellular responses. Leading exciting projects relating to lipid nanoparticle based therapeutics. Delivery of high quality experimental data and presenting this to external partners. Oversee and manage projects spanning multiple organisations, from conception to completion. Innovating in the in vivo imaging space to bring new technologies or ways of applying the technology to projects. Adhering to regulations and guidelines for in vivo work, including Home-Office project licence. Labelling / radiolabelling of LNPs (optional) Skills and Experience Needed: Suitable applicants must have: A PhD or Master's - focused around biological imaging (essential) Significant experience of developing pre-clinical in vivo mouse and rodent models (essential) Hold a personal Home Office PIL ABC licence (essential) Must have significant experience in positron emission tomography (PET) imaging and data analysis + image reconstruction tools (essential) Proven experience of routine in vivo techniques such as tissue collection, blood sampling, dosing via common routes etc (essential) Experience in leading, or influencing complex scientific projects (essential) Strong experience in ex vivo techniques like immunohistochemistry (IHC), immunofluorescence staining, microscopy etc (essential) Good communication and problem-solving skills (essential) Suitable applicants could have: Experience working on complex projects spanning across multiple organisation types (CRO, biotech, medical research charity, academia, etc) (desired) Experience in other in vivo imaging techniques including SPECT, IVIS, MRI etc (nice to have) PMOD image analysis software experience (desired) Radioligand labelling experience (nice to have) Working on lipid nanoparticle (LNP) within formulation, dosing or translational studies (nice to have) Prior industry experience in an SME or pharmaceutical company (desired) The Package Being a leading collaborative drug discovery company, our client is offering the chance to be part of a growing organisation on a temporary basis, with a competitive salary and benefits package. To Apply If you would like to submit an application for this position, please contact Charlie Cox on , or send an email to I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . Name Email address Telephone Message Upload C.V. Your file must be in one of the following formats: pdf , doc , docx , rtf , txt and no larger than 2MB . Recaptcha requires verification. I'm not a robot reCAPTCHA Privacy - Terms
Jul 15, 2025
Full time
Contract - Initially a 2 year fixed term contract - onsite. Salary - £40,000 - £45,000 depending on experience. Our client are a scientifically passionate company who lead extensive collaborations and offer services to the Drug Discovery and Disease Research sectors. They collaborate with lead researchers and organisations to enhance the understanding of immunological, oncological, neurological and other disease areas. Based in Alderley Park, they are offering an exciting opportunity for an enthusiastic and hard-working individual to join their in vivo imaging team as a Senior Scientist. If you are looking to work on exciting translational in vivo imaging projects and want to further your career, then this could be the opportunity you have been waiting for. The Role This is a role for experienced Imaging Scientists who hold a PhD (or Master's) in a biologically focused discipline, with additional postdoctoral or industry experience. As a Senior Imaging Scientist, you will be responsible for: Designing and running mouse + rodent PET / in vivo imaging studies for a range of purposes including biodistribution, pharmacokinetics (PK) and cellular responses. Leading exciting projects relating to lipid nanoparticle based therapeutics. Delivery of high quality experimental data and presenting this to external partners. Oversee and manage projects spanning multiple organisations, from conception to completion. Innovating in the in vivo imaging space to bring new technologies or ways of applying the technology to projects. Adhering to regulations and guidelines for in vivo work, including Home-Office project licence. Labelling / radiolabelling of LNPs (optional) Skills and Experience Needed: Suitable applicants must have: A PhD or Master's - focused around biological imaging (essential) Significant experience of developing pre-clinical in vivo mouse and rodent models (essential) Hold a personal Home Office PIL ABC licence (essential) Must have significant experience in positron emission tomography (PET) imaging and data analysis + image reconstruction tools (essential) Proven experience of routine in vivo techniques such as tissue collection, blood sampling, dosing via common routes etc (essential) Experience in leading, or influencing complex scientific projects (essential) Strong experience in ex vivo techniques like immunohistochemistry (IHC), immunofluorescence staining, microscopy etc (essential) Good communication and problem-solving skills (essential) Suitable applicants could have: Experience working on complex projects spanning across multiple organisation types (CRO, biotech, medical research charity, academia, etc) (desired) Experience in other in vivo imaging techniques including SPECT, IVIS, MRI etc (nice to have) PMOD image analysis software experience (desired) Radioligand labelling experience (nice to have) Working on lipid nanoparticle (LNP) within formulation, dosing or translational studies (nice to have) Prior industry experience in an SME or pharmaceutical company (desired) The Package Being a leading collaborative drug discovery company, our client is offering the chance to be part of a growing organisation on a temporary basis, with a competitive salary and benefits package. To Apply If you would like to submit an application for this position, please contact Charlie Cox on , or send an email to I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . Name Email address Telephone Message Upload C.V. Your file must be in one of the following formats: pdf , doc , docx , rtf , txt and no larger than 2MB . Recaptcha requires verification. I'm not a robot reCAPTCHA Privacy - Terms
MRC Postdoctoral Research Scientist LMS 2663
MediRecruit
View Vacancy MRC Postdoctoral Research Scientist LMS 2663 Open Date 11/07/2025, 10:00 Close Date 12/08/2025, 23:55 Research Institute MRC Laboratory of Medical Sciences Research Institute / Unit Information The LMS is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation , the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus (W12). The LMS aims to deliver transdisciplinary team science, in synergistic interaction with Imperial College and the wider national research environment. Part of achieving this, is to recruit new talent and support postdoctoral scientists to become world leaders in their area of science. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at Band MRC - 4 Location London £41,344 plus London allowances £5,385 per annum Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two Contract Type Fixed Term Job Type Science Full Time / Part Time Full Time 2 years (with a possibility of extension) Job Description Overall purpose: Understanding how the right cell types form in the right position and proportion during embryonic development represents one of the most important open questions in developmental biology. The Development & Transcriptional Control Group is tackling this challenge by investigating how cell identity is established and how it shapes the mammalian body. Our multidisciplinary approach integrates mouse developmental genetics, stem cell-based models of development, and genome engineering. These systems support quantitative and mechanistic studies, allowing us to address how cis-regulatory elements function and their effect on the body plan (Amblard et al., Dev Cell , 2025). We're seeking a highly motivatedpostdoctoral scientist to develop new tools and methodologies to uncover the gene regulatory principles of mammalian development. The role offers opportunities to pursue independent research ideas within the lab's core focus, with strong support for career development and scientific training. Main duties / key responsibilities: Design and conduct high-quality, independent research aligned with project aims Critically analyse, interpret, and present experimental data with rigor and reproducibility Stay up to date with relevant literature and integrate new findings and techniques into your research Develop and refine experimental methods and protocols as needed Participate fully in lab meetings, presenting research progress and contributing to discussions Provide support and mentorship to students and junior researchers as required Take part in journal clubs and internal seminar programmes Present findings at national and international conferences (where appropriate) Contribute to day-to-day lab operations and shared responsibilities Collaborate effectively within the group and with external collaborators Additional information: Applicants should have a PhD in a relevant discipline, with a strong commitment to scientific excellence and teamwork. This is an MRC Postdoctoral Scientist position to support post-doctoral training and help establish successful research scientists in their chosen field. During the fellowship tenure we are committed to provide mentorship for career development and improvement of communication skills. We also offer a highly attractive benefits package including competitive salary and salary pension scheme. Person Specification Education / Qualifications / Training required (will be assessed from the application): Essential: PhD (or equivalent experience) in a relevant biology field (e.g., molecular biology, cell biology, biochemistry, developmental biology, genetics) Previous work experience required (will be assessed from the application and at the interview ): Essential: Significant practical expertise in molecular biology techniques such as PCR, cloning, CRISPR/Cas9 Experience in design and/or generation and validation of new mammalian cell lines (eg. knockouts, reporters, epitope-tagging etc) Significant practical expertise in mammalian cell culture techniques Desirable: Experience working with embryonic stem cells as 2D/3D in vitro models of development, or mouse embryos or similar animal model organisms Experience in modifying embryonic stem cells using genome engineering approaches Experience in generating and/or analysing and integrating different high throughput sequencing data to study cell identity or gene regulation, such as ChIP-seq, Cut&Run, RNA-seq, ATAC-seq Knowledge and experience (will be assessed from the application and at the interview): Essential: Strong conceptual background and interest in at least one of the following: gene regulation in development, embryonic development, or stem cell models of development Excellent written communication skills in English Desirable: At least one first-author publication in a peer-reviewed international journal or available as a preprint Experience presenting scientific data at national or international scientific conferences Personal Skills / Behaviours / Qualities (will be assessed at interview) : Essential: Enthusiastic and collaborative team player Ability to conduct research independently, including the design, execution, and analysis of experiments Eagerness to learn and acquire new skills, troubleshoot experiments, and apply creative approaches to scientific questions Willingness to work flexible hours as needed by the project, and to travel for conferences or research collaborations Excellent verbal communication skills in English Further Information Applicants must submit the following to be considered: A CVA brief cover letter addressing: Motivation for joining the team How the applicant meets the selection criteria Names and contact details of two scientific referees Please note : Incomplete applications will not be considered. This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successfulapplicant is likely to be eligible to apply. Immigrationcosts for the applicant (100% visa and 100% Health Surcharge) and immediate dependents (100% visa and 50% health surcharge when applying with the main applicant) can be reclaimed from LMS after taking up the post (terms and conditions apply). Please note that applications may be reviewed by both LMS and Imperial staff The MRC is a unique working environment where scientific researchers and professional support staff can actively partake in world class innovation and collaboration opportunities and their skills and knowledge through accessing a wide catalogue of training & development, including professional registration with the Science Council. In addition, MRC (part of UKRI) provides its community of employees access to a whole host of useful benefits, including a defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We warmly invite people from diverse backgrounds and heritage, including people who identify as having a disability, to apply for a role that excites them. As "Disability Confident" employers, we guarantee to interview all applicants who have disclosed they have a disability and who meet the minimum criteria for the vacancy. UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs. We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check. The role holder will be required to have the appropriate level of security screening/vetting required for the role. UKRI reserves the right to run or re-run security clearance as required during the course of employment. Copyright 2015. Medical Research Council
Jul 15, 2025
Full time
View Vacancy MRC Postdoctoral Research Scientist LMS 2663 Open Date 11/07/2025, 10:00 Close Date 12/08/2025, 23:55 Research Institute MRC Laboratory of Medical Sciences Research Institute / Unit Information The LMS is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation , the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus (W12). The LMS aims to deliver transdisciplinary team science, in synergistic interaction with Imperial College and the wider national research environment. Part of achieving this, is to recruit new talent and support postdoctoral scientists to become world leaders in their area of science. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at Band MRC - 4 Location London £41,344 plus London allowances £5,385 per annum Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two Contract Type Fixed Term Job Type Science Full Time / Part Time Full Time 2 years (with a possibility of extension) Job Description Overall purpose: Understanding how the right cell types form in the right position and proportion during embryonic development represents one of the most important open questions in developmental biology. The Development & Transcriptional Control Group is tackling this challenge by investigating how cell identity is established and how it shapes the mammalian body. Our multidisciplinary approach integrates mouse developmental genetics, stem cell-based models of development, and genome engineering. These systems support quantitative and mechanistic studies, allowing us to address how cis-regulatory elements function and their effect on the body plan (Amblard et al., Dev Cell , 2025). We're seeking a highly motivatedpostdoctoral scientist to develop new tools and methodologies to uncover the gene regulatory principles of mammalian development. The role offers opportunities to pursue independent research ideas within the lab's core focus, with strong support for career development and scientific training. Main duties / key responsibilities: Design and conduct high-quality, independent research aligned with project aims Critically analyse, interpret, and present experimental data with rigor and reproducibility Stay up to date with relevant literature and integrate new findings and techniques into your research Develop and refine experimental methods and protocols as needed Participate fully in lab meetings, presenting research progress and contributing to discussions Provide support and mentorship to students and junior researchers as required Take part in journal clubs and internal seminar programmes Present findings at national and international conferences (where appropriate) Contribute to day-to-day lab operations and shared responsibilities Collaborate effectively within the group and with external collaborators Additional information: Applicants should have a PhD in a relevant discipline, with a strong commitment to scientific excellence and teamwork. This is an MRC Postdoctoral Scientist position to support post-doctoral training and help establish successful research scientists in their chosen field. During the fellowship tenure we are committed to provide mentorship for career development and improvement of communication skills. We also offer a highly attractive benefits package including competitive salary and salary pension scheme. Person Specification Education / Qualifications / Training required (will be assessed from the application): Essential: PhD (or equivalent experience) in a relevant biology field (e.g., molecular biology, cell biology, biochemistry, developmental biology, genetics) Previous work experience required (will be assessed from the application and at the interview ): Essential: Significant practical expertise in molecular biology techniques such as PCR, cloning, CRISPR/Cas9 Experience in design and/or generation and validation of new mammalian cell lines (eg. knockouts, reporters, epitope-tagging etc) Significant practical expertise in mammalian cell culture techniques Desirable: Experience working with embryonic stem cells as 2D/3D in vitro models of development, or mouse embryos or similar animal model organisms Experience in modifying embryonic stem cells using genome engineering approaches Experience in generating and/or analysing and integrating different high throughput sequencing data to study cell identity or gene regulation, such as ChIP-seq, Cut&Run, RNA-seq, ATAC-seq Knowledge and experience (will be assessed from the application and at the interview): Essential: Strong conceptual background and interest in at least one of the following: gene regulation in development, embryonic development, or stem cell models of development Excellent written communication skills in English Desirable: At least one first-author publication in a peer-reviewed international journal or available as a preprint Experience presenting scientific data at national or international scientific conferences Personal Skills / Behaviours / Qualities (will be assessed at interview) : Essential: Enthusiastic and collaborative team player Ability to conduct research independently, including the design, execution, and analysis of experiments Eagerness to learn and acquire new skills, troubleshoot experiments, and apply creative approaches to scientific questions Willingness to work flexible hours as needed by the project, and to travel for conferences or research collaborations Excellent verbal communication skills in English Further Information Applicants must submit the following to be considered: A CVA brief cover letter addressing: Motivation for joining the team How the applicant meets the selection criteria Names and contact details of two scientific referees Please note : Incomplete applications will not be considered. This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successfulapplicant is likely to be eligible to apply. Immigrationcosts for the applicant (100% visa and 100% Health Surcharge) and immediate dependents (100% visa and 50% health surcharge when applying with the main applicant) can be reclaimed from LMS after taking up the post (terms and conditions apply). Please note that applications may be reviewed by both LMS and Imperial staff The MRC is a unique working environment where scientific researchers and professional support staff can actively partake in world class innovation and collaboration opportunities and their skills and knowledge through accessing a wide catalogue of training & development, including professional registration with the Science Council. In addition, MRC (part of UKRI) provides its community of employees access to a whole host of useful benefits, including a defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We warmly invite people from diverse backgrounds and heritage, including people who identify as having a disability, to apply for a role that excites them. As "Disability Confident" employers, we guarantee to interview all applicants who have disclosed they have a disability and who meet the minimum criteria for the vacancy. UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs. We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check. The role holder will be required to have the appropriate level of security screening/vetting required for the role. UKRI reserves the right to run or re-run security clearance as required during the course of employment. Copyright 2015. Medical Research Council
Barts Cancer Institute, Queen Mary University London
Postdoctoral Research Associate
Barts Cancer Institute, Queen Mary University London Croydon, London
About the Role Postdoctoral Research Assistant to join Dr Gallipoli's team (). We study the biological mechanisms underpinning myeloid leukaemia development, progression and therapy resistance with a strong focus on the role of metabolism (Dembitz, Leukemia 2024;Woodley, Nature Communication 2023&Gallipoli, Blood 2018). The successful applicant will investigate how microenvironmental and organismal metabolism affects leukaemia cell intrinsic targetable dependencies with the aim to improve current therapeutics efficacy. About You We are seeking highly-motivated researchers holding or near completion of a PhD in a relevant biological or life sciences subject. The ability to develop independent insights into the project, solve complex problems and willingness to work flexibly within a team to achieve the project demands are needed. Experience with flow cytometry, primary cell culture, molecular biology, animal work, metabolic/transcriptional profiling is highly desirable. About the School/Department/Institute/Project The Barts Cancer Institute (BCI) is a Cancer Research UK Centre of Excellence whose work aims to transform the lives of those with and at risk of cancer through innovative research in the laboratory, in patients and in populations. It is one of six institutes within The Faculty of Medicine and Dentistry (FMD) BCI is internationally renowned in many areas of cancer research and it combines ground-breaking basic research with the expertise of clinicians and clinician scientists from the Centre for Experimental Cancer Medicine and the Barts NHS Trust to achieve improvements in cancer patient care. BCI is also a partner in the CRUK City of London Major Centre (together with UCL, Kings and the Francis Crick Institute) which is a Centre of Excellence in Biotherapeutics. BCI is committed in supporting and developing future cancer researchers through its extensive postgraduate training. About Queen Mary At Queen Mary University of London, we believe that a diversity of ideas helps us achieve the previously unthinkable. Throughout our history, we've fostered social justice and improved lives through academic excellence. And we continue to live and breathe this spirit today, not because it's simply 'the right thing to do' but for what it helps us achieve and the intellectual brilliance it delivers. We continue to embrace diversity of thought and opinion in everything we do, in the belief that when views collide, disciplines interact, and perspectives intersect, truly original thought takes form. Benefits We offer competitive salaries, access to a generous pension scheme, 30 days' leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities. The post is based at the Centre for Haemato-Oncology, Barts Cancer Institute, Charterhouse Square Campus. It is full time, fixed term for 12 months, with an expected start date of October 2025. The starting salary will be Grade 4 (Sp 26-33), in the range of Grade 4, SP 26-33, £37,887 - £45,974 per annum, inclusive of London Allowance. Queen Mary's commitment to our diverse and inclusive community is embedded in our appointments processes. Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly. Closing Date 24/07/2025, 23:55
Jul 13, 2025
Full time
About the Role Postdoctoral Research Assistant to join Dr Gallipoli's team (). We study the biological mechanisms underpinning myeloid leukaemia development, progression and therapy resistance with a strong focus on the role of metabolism (Dembitz, Leukemia 2024;Woodley, Nature Communication 2023&Gallipoli, Blood 2018). The successful applicant will investigate how microenvironmental and organismal metabolism affects leukaemia cell intrinsic targetable dependencies with the aim to improve current therapeutics efficacy. About You We are seeking highly-motivated researchers holding or near completion of a PhD in a relevant biological or life sciences subject. The ability to develop independent insights into the project, solve complex problems and willingness to work flexibly within a team to achieve the project demands are needed. Experience with flow cytometry, primary cell culture, molecular biology, animal work, metabolic/transcriptional profiling is highly desirable. About the School/Department/Institute/Project The Barts Cancer Institute (BCI) is a Cancer Research UK Centre of Excellence whose work aims to transform the lives of those with and at risk of cancer through innovative research in the laboratory, in patients and in populations. It is one of six institutes within The Faculty of Medicine and Dentistry (FMD) BCI is internationally renowned in many areas of cancer research and it combines ground-breaking basic research with the expertise of clinicians and clinician scientists from the Centre for Experimental Cancer Medicine and the Barts NHS Trust to achieve improvements in cancer patient care. BCI is also a partner in the CRUK City of London Major Centre (together with UCL, Kings and the Francis Crick Institute) which is a Centre of Excellence in Biotherapeutics. BCI is committed in supporting and developing future cancer researchers through its extensive postgraduate training. About Queen Mary At Queen Mary University of London, we believe that a diversity of ideas helps us achieve the previously unthinkable. Throughout our history, we've fostered social justice and improved lives through academic excellence. And we continue to live and breathe this spirit today, not because it's simply 'the right thing to do' but for what it helps us achieve and the intellectual brilliance it delivers. We continue to embrace diversity of thought and opinion in everything we do, in the belief that when views collide, disciplines interact, and perspectives intersect, truly original thought takes form. Benefits We offer competitive salaries, access to a generous pension scheme, 30 days' leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities. The post is based at the Centre for Haemato-Oncology, Barts Cancer Institute, Charterhouse Square Campus. It is full time, fixed term for 12 months, with an expected start date of October 2025. The starting salary will be Grade 4 (Sp 26-33), in the range of Grade 4, SP 26-33, £37,887 - £45,974 per annum, inclusive of London Allowance. Queen Mary's commitment to our diverse and inclusive community is embedded in our appointments processes. Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly. Closing Date 24/07/2025, 23:55
Barts Cancer Institute, Queen Mary University London
Postdoctoral Research Associate
Barts Cancer Institute, Queen Mary University London Croydon, London
About the Role Postdoctoral Research Assistant to join Dr Gallipoli's team (). We study the biological mechanisms underpinning myeloid leukaemia development, progression and therapy resistance with a strong focus on the role of metabolism (Dembitz, Leukemia 2024;Woodley, Nature Communication 2023&Gallipoli, Blood 2018). The successful applicant will investigate how microenvironmental and organismal metabolism affects leukaemia cell intrinsic targetable dependencies with the aim to improve current therapeutics efficacy. About You We are seeking highly-motivated researchers holding or near completion of a PhD in a relevant biological or life sciences subject. The ability to develop independent insights into the project, solve complex problems and willingness to work flexibly within a team to achieve the project demands are needed. Experience with flow cytometry, primary cell culture, molecular biology, animal work, metabolic/transcriptional profiling is highly desirable. About the School/Department/Institute/Project The Barts Cancer Institute (BCI) is a Cancer Research UK Centre of Excellence whose work aims to transform the lives of those with and at risk of cancer through innovative research in the laboratory, in patients and in populations. It is one of six institutes within The Faculty of Medicine and Dentistry (FMD) BCI is internationally renowned in many areas of cancer research and it combines ground-breaking basic research with the expertise of clinicians and clinician scientists from the Centre for Experimental Cancer Medicine and the Barts NHS Trust to achieve improvements in cancer patient care. BCI is also a partner in the CRUK City of London Major Centre (together with UCL, Kings and the Francis Crick Institute) which is a Centre of Excellence in Biotherapeutics. BCI is committed in supporting and developing future cancer researchers through its extensive postgraduate training. About Queen Mary At Queen Mary University of London, we believe that a diversity of ideas helps us achieve the previously unthinkable. Throughout our history, we've fostered social justice and improved lives through academic excellence. And we continue to live and breathe this spirit today, not because it's simply 'the right thing to do' but for what it helps us achieve and the intellectual brilliance it delivers. We continue to embrace diversity of thought and opinion in everything we do, in the belief that when views collide, disciplines interact, and perspectives intersect, truly original thought takes form. Benefits We offer competitive salaries, access to a generous pension scheme, 30 days' leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities. The post is based at the Centre for Haemato-Oncology, Barts Cancer Institute, Charterhouse Square Campus. It is full time, fixed term for 12 months, with an expected start date of October 2025. The starting salary will be Grade 4 (Sp 26-33), in the range of Grade 4, SP 26-33, £37,887 - £45,974 per annum, inclusive of London Allowance. Queen Mary's commitment to our diverse and inclusive community is embedded in our appointments processes. Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly. Closing Date 24/07/2025, 23:55
Jul 12, 2025
Full time
About the Role Postdoctoral Research Assistant to join Dr Gallipoli's team (). We study the biological mechanisms underpinning myeloid leukaemia development, progression and therapy resistance with a strong focus on the role of metabolism (Dembitz, Leukemia 2024;Woodley, Nature Communication 2023&Gallipoli, Blood 2018). The successful applicant will investigate how microenvironmental and organismal metabolism affects leukaemia cell intrinsic targetable dependencies with the aim to improve current therapeutics efficacy. About You We are seeking highly-motivated researchers holding or near completion of a PhD in a relevant biological or life sciences subject. The ability to develop independent insights into the project, solve complex problems and willingness to work flexibly within a team to achieve the project demands are needed. Experience with flow cytometry, primary cell culture, molecular biology, animal work, metabolic/transcriptional profiling is highly desirable. About the School/Department/Institute/Project The Barts Cancer Institute (BCI) is a Cancer Research UK Centre of Excellence whose work aims to transform the lives of those with and at risk of cancer through innovative research in the laboratory, in patients and in populations. It is one of six institutes within The Faculty of Medicine and Dentistry (FMD) BCI is internationally renowned in many areas of cancer research and it combines ground-breaking basic research with the expertise of clinicians and clinician scientists from the Centre for Experimental Cancer Medicine and the Barts NHS Trust to achieve improvements in cancer patient care. BCI is also a partner in the CRUK City of London Major Centre (together with UCL, Kings and the Francis Crick Institute) which is a Centre of Excellence in Biotherapeutics. BCI is committed in supporting and developing future cancer researchers through its extensive postgraduate training. About Queen Mary At Queen Mary University of London, we believe that a diversity of ideas helps us achieve the previously unthinkable. Throughout our history, we've fostered social justice and improved lives through academic excellence. And we continue to live and breathe this spirit today, not because it's simply 'the right thing to do' but for what it helps us achieve and the intellectual brilliance it delivers. We continue to embrace diversity of thought and opinion in everything we do, in the belief that when views collide, disciplines interact, and perspectives intersect, truly original thought takes form. Benefits We offer competitive salaries, access to a generous pension scheme, 30 days' leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities. The post is based at the Centre for Haemato-Oncology, Barts Cancer Institute, Charterhouse Square Campus. It is full time, fixed term for 12 months, with an expected start date of October 2025. The starting salary will be Grade 4 (Sp 26-33), in the range of Grade 4, SP 26-33, £37,887 - £45,974 per annum, inclusive of London Allowance. Queen Mary's commitment to our diverse and inclusive community is embedded in our appointments processes. Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly. Closing Date 24/07/2025, 23:55
Research Scientist
Geophysics
Rebecca is a Research Scientist working at Natural Resources Canada /Geological Survey of Canada. She did an MSci Geology with study in North America at the University of Bristol followed by a Ph.D. in Geophysics (Seismology) at the University of Leeds. Can you give a brief description of what the company/employer does and how your role fits in? The Geological Survey of Canada (GSC) is the national organization for geoscientific information and research. Our work supports exploration and decision-making in the mining and energy sectors as well as national sovereignty, hazards risk management and more. I work in the Critical Minerals Geoscience and Data division, as well as the Induced Seismicity Research division. My research focuses on using geophysics (seismic, fiber optic technology) to identify structural controls for critical minerals in Canada, as well as using remote sensing satellite techniques to identify mineral systems. In addition to this, I am involved in projects relating to the causes and consequences of natural and induced seismicity from resource development projects including oil and gas, water disposal, geothermal and CCUS. As a research scientist, I am responsible for the development of research ideas, project oversight (including planning, procurement and financial elements), fieldwork planning and execution, data analysis and dissemination, interactions with external parties including private companies and First Nation Peoples and navigating both the government and academic systems (e.g. publishing, funding etc.). What does a typical day in your working life look like? My days are extremely varied - I could be planning research or fieldwork, analyzing data, in the field or disseminating results at a conference or in a written publication to the public or colleagues. For example, this week I have attended several weekly development meetings with different students and colleagues, written a job advertisement for a student hire, attended a 2 day workshop (online) relating to geothermal processes where I was part of a group presentation, done some python coding to obtain magnitudes of several earthquake swarms, done paperwork associated with the procurement of several pieces of field equipment, and planned a reconnaissance field trip to my field site in September. What was your pathway to what you do for your job now? Prior to joining the Geological Survey of Canada, I was a Research/Postdoctoral Associate at the University of Calgary () with research focused in induced and microsiesmicity as a result of resource development in western Canada. This included using detailed temporal and spatial analysis of seismicity, ambient seismic noise and new technologies including fiber optics, to better understand how fractures grow and develop; how highly pressurized fluids move through developing fracture networks; and in the identification and progression of slow slip events to better understand the continuum from aseismic to seismic slip. From I was a Profesor Visitante at the Observatorio Vulcanologico y Sismologico de Costa Rica, undertaking real time monitoring of tectonic and volcanic seismicity in Costa Rica and Central America. I obtained my PhD in Geophysics from the University of Leeds, UK (2015) with focus in using seismicity as a forecasting tool for volcanic eruptions, and hold a Masters and Undergraduate degree in Geology from the University of Bristol, UK (2011). What advice would you give to someone interested in pursuing a career like yours? Take every opportunity you can, even if it doesn't seem like anything will come out of it. Try and meet as many people as possible (attend guest lectures, conferences if you can, reach out via email if possible). Don't be scared to apply for jobs/positions where you don't meet 100% of the criteria - you never know what they are looking for and usually job postings are an absolute wish list that no candidate is ever likely to have!
Jul 10, 2025
Full time
Rebecca is a Research Scientist working at Natural Resources Canada /Geological Survey of Canada. She did an MSci Geology with study in North America at the University of Bristol followed by a Ph.D. in Geophysics (Seismology) at the University of Leeds. Can you give a brief description of what the company/employer does and how your role fits in? The Geological Survey of Canada (GSC) is the national organization for geoscientific information and research. Our work supports exploration and decision-making in the mining and energy sectors as well as national sovereignty, hazards risk management and more. I work in the Critical Minerals Geoscience and Data division, as well as the Induced Seismicity Research division. My research focuses on using geophysics (seismic, fiber optic technology) to identify structural controls for critical minerals in Canada, as well as using remote sensing satellite techniques to identify mineral systems. In addition to this, I am involved in projects relating to the causes and consequences of natural and induced seismicity from resource development projects including oil and gas, water disposal, geothermal and CCUS. As a research scientist, I am responsible for the development of research ideas, project oversight (including planning, procurement and financial elements), fieldwork planning and execution, data analysis and dissemination, interactions with external parties including private companies and First Nation Peoples and navigating both the government and academic systems (e.g. publishing, funding etc.). What does a typical day in your working life look like? My days are extremely varied - I could be planning research or fieldwork, analyzing data, in the field or disseminating results at a conference or in a written publication to the public or colleagues. For example, this week I have attended several weekly development meetings with different students and colleagues, written a job advertisement for a student hire, attended a 2 day workshop (online) relating to geothermal processes where I was part of a group presentation, done some python coding to obtain magnitudes of several earthquake swarms, done paperwork associated with the procurement of several pieces of field equipment, and planned a reconnaissance field trip to my field site in September. What was your pathway to what you do for your job now? Prior to joining the Geological Survey of Canada, I was a Research/Postdoctoral Associate at the University of Calgary () with research focused in induced and microsiesmicity as a result of resource development in western Canada. This included using detailed temporal and spatial analysis of seismicity, ambient seismic noise and new technologies including fiber optics, to better understand how fractures grow and develop; how highly pressurized fluids move through developing fracture networks; and in the identification and progression of slow slip events to better understand the continuum from aseismic to seismic slip. From I was a Profesor Visitante at the Observatorio Vulcanologico y Sismologico de Costa Rica, undertaking real time monitoring of tectonic and volcanic seismicity in Costa Rica and Central America. I obtained my PhD in Geophysics from the University of Leeds, UK (2015) with focus in using seismicity as a forecasting tool for volcanic eruptions, and hold a Masters and Undergraduate degree in Geology from the University of Bristol, UK (2011). What advice would you give to someone interested in pursuing a career like yours? Take every opportunity you can, even if it doesn't seem like anything will come out of it. Try and meet as many people as possible (attend guest lectures, conferences if you can, reach out via email if possible). Don't be scared to apply for jobs/positions where you don't meet 100% of the criteria - you never know what they are looking for and usually job postings are an absolute wish list that no candidate is ever likely to have!
Postdoctoral Research Associate/Assistant in Biochemistry
The World Aquaculture Society Oban, Argyllshire
Postdoctoral Research Associate/Assistant in Biochemistry Oban Full Time Job Details You will play a key role in advancing algal biotechnology by generating high-quality empirical datasets on the metabolic composition and activity of NERC-UKRI CCAP algal strains. The successful candidate will contribute to expanding the biotechnological potential of these strains, particularly for applications in the agri- and aquaculture sectors, while enhancing SAMS' research capacity in metabolomics and natural products. The role will focus on three core activities: overseeing untargeted biochemical phenotype screening across the CCAP collection, conducting full-trait characterisation of key sector-relevant strains within CCAP, and optimising bioassays to identify and quantify bioactivity of selected strains. This post is central to increasing the biotechnological value of the CCAP holdings and strengthening SAMS' research profile in this growing field. This work will be part of the Natural Products BioHUB project that we have in partnership with Swansea University (lead partner) and CABI. See project details here: You will work under the guidance of Lecturer in Algal Biotechnology/CCAP Manager and Associate Professor of Physiological Ecology. Ideally, we are looking for the successful candidate to start no later than 1st October 2025. Requirements We are seeking a post-doctoral researcher with a PhD in Phycology, Algal Biotechnology, or Biochemistry, ideally with a strong biochemistry focus. The ideal candidate will have experience in phycology/algal biotechnology involving either macroalgae and/or microalgae, and a proven ability to work effectively within interdisciplinary teams. A solid foundation in experimental design and method development in analytical biochemistry and biology is essential. The successful applicant will demonstrate strong written and verbal communication skills to effectively convey scientific findings. Experience with analytical techniques such as GC-MS and HPLC is highly desirable and will be considered a significant advantage. Contact Information Scottish Association for Marine Science SAMS We would love to hear from you. If you have queries on the job and would like to talk these through before applying, please email these through, in the first instance, to Dr Michael Ross - Applications must include CV and Cover Letter and should be sent electronically to quoting Job Ref. 'D05/25.MR' in the subject heading. Closing date for applications is 27th July 2025 - Interviews to be held shortly thereafter. Please note, we are unfortunately unable to provide visa sponsorship for this position. Full details, and guidance on applying, can be found here: Post Date: 7/6/2025 9:47:29 AM Closing Date: 7/27/:00:00 AM Share this job About this company SAMS is Scotland's largest independent marine research organisation delivering innovative, world-class marine science solutions to developing a sustainable relationship with the marine environment. This is done through research, education, services to business, and public engagement. SAMS has research expertise in areas including Arctic seas, marine renewable energy, people and the sea, and dynamic oceans. SAMS operates the modern and well-equipped Scottish Marine Institute at the scenic Dunstaffnage Peninsula near Oban, Argyll, and currently employs over 160 staff - including physical oceanographers, hydrographers, marine geologists, biogeochemists, microbial and molecular biologists, ecologists, social scientists, and modellers. About this company SAMS is Scotland's largest independent marine research organisation delivering innovative, world-class marine science solutions to developing a sustainable relationship with the marine environment. This is done through research, education, services to business, and public engagement. SAMS has research expertise in areas including Arctic seas, marine renewable energy, people and the sea, and dynamic oceans. SAMS operates the modern and well-equipped Scottish Marine Institute at the scenic Dunstaffnage Peninsula near Oban, Argyll, and currently employs over 160 staff - including physical oceanographers, hydrographers, marine geologists, biogeochemists, microbial and molecular biologists, ecologists, social scientists, and modellers. Read more
Jul 09, 2025
Full time
Postdoctoral Research Associate/Assistant in Biochemistry Oban Full Time Job Details You will play a key role in advancing algal biotechnology by generating high-quality empirical datasets on the metabolic composition and activity of NERC-UKRI CCAP algal strains. The successful candidate will contribute to expanding the biotechnological potential of these strains, particularly for applications in the agri- and aquaculture sectors, while enhancing SAMS' research capacity in metabolomics and natural products. The role will focus on three core activities: overseeing untargeted biochemical phenotype screening across the CCAP collection, conducting full-trait characterisation of key sector-relevant strains within CCAP, and optimising bioassays to identify and quantify bioactivity of selected strains. This post is central to increasing the biotechnological value of the CCAP holdings and strengthening SAMS' research profile in this growing field. This work will be part of the Natural Products BioHUB project that we have in partnership with Swansea University (lead partner) and CABI. See project details here: You will work under the guidance of Lecturer in Algal Biotechnology/CCAP Manager and Associate Professor of Physiological Ecology. Ideally, we are looking for the successful candidate to start no later than 1st October 2025. Requirements We are seeking a post-doctoral researcher with a PhD in Phycology, Algal Biotechnology, or Biochemistry, ideally with a strong biochemistry focus. The ideal candidate will have experience in phycology/algal biotechnology involving either macroalgae and/or microalgae, and a proven ability to work effectively within interdisciplinary teams. A solid foundation in experimental design and method development in analytical biochemistry and biology is essential. The successful applicant will demonstrate strong written and verbal communication skills to effectively convey scientific findings. Experience with analytical techniques such as GC-MS and HPLC is highly desirable and will be considered a significant advantage. Contact Information Scottish Association for Marine Science SAMS We would love to hear from you. If you have queries on the job and would like to talk these through before applying, please email these through, in the first instance, to Dr Michael Ross - Applications must include CV and Cover Letter and should be sent electronically to quoting Job Ref. 'D05/25.MR' in the subject heading. Closing date for applications is 27th July 2025 - Interviews to be held shortly thereafter. Please note, we are unfortunately unable to provide visa sponsorship for this position. Full details, and guidance on applying, can be found here: Post Date: 7/6/2025 9:47:29 AM Closing Date: 7/27/:00:00 AM Share this job About this company SAMS is Scotland's largest independent marine research organisation delivering innovative, world-class marine science solutions to developing a sustainable relationship with the marine environment. This is done through research, education, services to business, and public engagement. SAMS has research expertise in areas including Arctic seas, marine renewable energy, people and the sea, and dynamic oceans. SAMS operates the modern and well-equipped Scottish Marine Institute at the scenic Dunstaffnage Peninsula near Oban, Argyll, and currently employs over 160 staff - including physical oceanographers, hydrographers, marine geologists, biogeochemists, microbial and molecular biologists, ecologists, social scientists, and modellers. About this company SAMS is Scotland's largest independent marine research organisation delivering innovative, world-class marine science solutions to developing a sustainable relationship with the marine environment. This is done through research, education, services to business, and public engagement. SAMS has research expertise in areas including Arctic seas, marine renewable energy, people and the sea, and dynamic oceans. SAMS operates the modern and well-equipped Scottish Marine Institute at the scenic Dunstaffnage Peninsula near Oban, Argyll, and currently employs over 160 staff - including physical oceanographers, hydrographers, marine geologists, biogeochemists, microbial and molecular biologists, ecologists, social scientists, and modellers. Read more
Anson McCade Ltd - IT and Finance Recruitment
Research Scientist - Knowledge & Semantics
Anson McCade Ltd - IT and Finance Recruitment
Research Scientist - Knowledge & Semantics Bonus Hybrid WORKING Location: United Kingdom (Greater London - Chelmsford) Type: Permanent Research Scientist - Knowledge & Semantics Chelmsford (Hybrid - 2 days onsite per week) £60,000 - £70,000 + 10% Bonus Security Clearance: Must be eligible for UK SC Clearance A globally respected research and technology organisation is seeking a Research Scientist to join its Knowledge and Semantics team within a leading-edge AI and data science capability. This is a unique opportunity to shape the future of knowledge-driven AI, working at the intersection of knowledge graphs, machine learning, NLP, and semantic reasoning-supporting missions across defence, security, and advanced technologies. Working within a multi-disciplinary research team, you'll lead the development of innovative solutions using graph machine learning, LLMs, and knowledge representation. You'll also collaborate with UK universities and SME partners, contribute to internal IP, and drive research that translates into operational capability. What you'll be doing: Leading technical delivery of applied AI projects in NLP, semantics, and knowledge representation Developing prototypes and proof-of-concept tools using Python and ML frameworks Securing research funding and writing technical proposals Mentoring junior researchers and providing technical leadership across graph and semantic AI Presenting to customers and stakeholders across defence, security, and research communities What we're looking for: PhD (or equivalent experience) in a relevant AI/ML discipline 4+ years of postdoctoral or industry experience leading research teams Strong programming skills in Python and experience with frameworks like PyTorch or TensorFlow Deep expertise in one or more of: NLP, LLMs, graph machine learning, semantic AI, or knowledge graphs Proven track record of winning and delivering R&D projects Please note: Due to the nature of the work, candidates must be eligible for UK Security Clearance, which typically requires at least 5 years of continuous UK residency. Package: 10% bonus Pension Medical cover To hear more about the Research Scientist - Knowledge & Semantics opportunity, get in touch with Connor Smyth at Anson McCade on . Reference: AMC/CSM/RSKS Postcode: CM1 1HT Apply for this vacancy Your CV will be sent to the selected department. At no time will your CV be sent outside of Anson McCade without your authorisation. Mandatory field. Your name I confirm I currently have the right to take full time employment at the location for which I am submitting my CV. Please state the locations where you currently have the right to take full time employment. Attach a file (Word or PDF only accepted)
Jul 09, 2025
Full time
Research Scientist - Knowledge & Semantics Bonus Hybrid WORKING Location: United Kingdom (Greater London - Chelmsford) Type: Permanent Research Scientist - Knowledge & Semantics Chelmsford (Hybrid - 2 days onsite per week) £60,000 - £70,000 + 10% Bonus Security Clearance: Must be eligible for UK SC Clearance A globally respected research and technology organisation is seeking a Research Scientist to join its Knowledge and Semantics team within a leading-edge AI and data science capability. This is a unique opportunity to shape the future of knowledge-driven AI, working at the intersection of knowledge graphs, machine learning, NLP, and semantic reasoning-supporting missions across defence, security, and advanced technologies. Working within a multi-disciplinary research team, you'll lead the development of innovative solutions using graph machine learning, LLMs, and knowledge representation. You'll also collaborate with UK universities and SME partners, contribute to internal IP, and drive research that translates into operational capability. What you'll be doing: Leading technical delivery of applied AI projects in NLP, semantics, and knowledge representation Developing prototypes and proof-of-concept tools using Python and ML frameworks Securing research funding and writing technical proposals Mentoring junior researchers and providing technical leadership across graph and semantic AI Presenting to customers and stakeholders across defence, security, and research communities What we're looking for: PhD (or equivalent experience) in a relevant AI/ML discipline 4+ years of postdoctoral or industry experience leading research teams Strong programming skills in Python and experience with frameworks like PyTorch or TensorFlow Deep expertise in one or more of: NLP, LLMs, graph machine learning, semantic AI, or knowledge graphs Proven track record of winning and delivering R&D projects Please note: Due to the nature of the work, candidates must be eligible for UK Security Clearance, which typically requires at least 5 years of continuous UK residency. Package: 10% bonus Pension Medical cover To hear more about the Research Scientist - Knowledge & Semantics opportunity, get in touch with Connor Smyth at Anson McCade on . Reference: AMC/CSM/RSKS Postcode: CM1 1HT Apply for this vacancy Your CV will be sent to the selected department. At no time will your CV be sent outside of Anson McCade without your authorisation. Mandatory field. Your name I confirm I currently have the right to take full time employment at the location for which I am submitting my CV. Please state the locations where you currently have the right to take full time employment. Attach a file (Word or PDF only accepted)
Four Squared Recruitment Ltd
Environmental Risk Modeller
Four Squared Recruitment Ltd Cambridge, Cambridgeshire
Environmental Risk Modeller Location: Cambridge, Cambridgeshire (Hybrid) Salary: 60-85k Job Type: Full-time, Permanent About the Role We are seeking a quantitative modeller to support the development of climate physical risk and nature modelling efforts for an innovative and fast-growing organisation. The successful candidate will be responsible for quantifying the impacts and dependencies of businesses on climate and nature, working alongside a talented team of modellers, economists, data scientists, and software engineers. This is an exciting opportunity for an ambitious individual looking to work on cutting-edge analytics with some of the world s largest and most forward-thinking corporations. Key Responsibilities Develop models using novel techniques to assess risks from climate change and nature, translating complex scientific concepts into quantified financial impacts for businesses. Write Python code to integrate models into the company s analytics platform. Build and analyse geospatial data layers to support risk modelling. Deliver actionable insights and analytics relevant to corporate decision-making. Act as a subject matter expert on nature and climate-related risks and opportunities. Collaborate with internal teams and clients, requiring a minimum of three days per week in the Cambridge office. Essential Skills & Experience A Bachelor s degree in natural sciences, physics, engineering, or a related field. Experience delivering environmental or sustainability-related projects to corporate clients. Strong knowledge of mathematical modelling, including statistics, geospatial analysis, and probability, with practical applications to real-world problems. Proficiency in Python (preferred), R, or MATLAB for scientific programming. Experience working with large geospatial and environmental datasets (e.g., CMIP6, SSPs, or nature data layers). Strong research skills with the ability to translate data into actionable models and insights. Excellent communication skills, with the ability to present complex scientific concepts to non-technical audiences. Ability to work effectively in a fast-paced environment, managing multiple projects while collaborating with a diverse team of scientists and engineers. Desirable Skills Postdoctoral research experience in a relevant field. Experience in model development (e.g., natural catastrophe modelling, risk quantification). Cross-disciplinary expertise in areas such as natural sciences, agronomy, or environmental economics. Experience quantifying the economic impact of climate and nature-related risks to inform business or government decision-making. Why Join? Be part of a rapidly growing organisation at the forefront of climate and environmental risk modelling. Work on high-impact projects with leading global corporations. Collaborate with a highly skilled team of scientists, engineers, and industry experts. Competitive salary and opportunities for career progression.
Feb 21, 2025
Full time
Environmental Risk Modeller Location: Cambridge, Cambridgeshire (Hybrid) Salary: 60-85k Job Type: Full-time, Permanent About the Role We are seeking a quantitative modeller to support the development of climate physical risk and nature modelling efforts for an innovative and fast-growing organisation. The successful candidate will be responsible for quantifying the impacts and dependencies of businesses on climate and nature, working alongside a talented team of modellers, economists, data scientists, and software engineers. This is an exciting opportunity for an ambitious individual looking to work on cutting-edge analytics with some of the world s largest and most forward-thinking corporations. Key Responsibilities Develop models using novel techniques to assess risks from climate change and nature, translating complex scientific concepts into quantified financial impacts for businesses. Write Python code to integrate models into the company s analytics platform. Build and analyse geospatial data layers to support risk modelling. Deliver actionable insights and analytics relevant to corporate decision-making. Act as a subject matter expert on nature and climate-related risks and opportunities. Collaborate with internal teams and clients, requiring a minimum of three days per week in the Cambridge office. Essential Skills & Experience A Bachelor s degree in natural sciences, physics, engineering, or a related field. Experience delivering environmental or sustainability-related projects to corporate clients. Strong knowledge of mathematical modelling, including statistics, geospatial analysis, and probability, with practical applications to real-world problems. Proficiency in Python (preferred), R, or MATLAB for scientific programming. Experience working with large geospatial and environmental datasets (e.g., CMIP6, SSPs, or nature data layers). Strong research skills with the ability to translate data into actionable models and insights. Excellent communication skills, with the ability to present complex scientific concepts to non-technical audiences. Ability to work effectively in a fast-paced environment, managing multiple projects while collaborating with a diverse team of scientists and engineers. Desirable Skills Postdoctoral research experience in a relevant field. Experience in model development (e.g., natural catastrophe modelling, risk quantification). Cross-disciplinary expertise in areas such as natural sciences, agronomy, or environmental economics. Experience quantifying the economic impact of climate and nature-related risks to inform business or government decision-making. Why Join? Be part of a rapidly growing organisation at the forefront of climate and environmental risk modelling. Work on high-impact projects with leading global corporations. Collaborate with a highly skilled team of scientists, engineers, and industry experts. Competitive salary and opportunities for career progression.
Post Doctorate Scheme 2025 - Nuclear Scientist and Nuclear Engineer
National Nuclear Laboratory Limited Seascale, Cumbria
Job Description This is where your skills play a critical role in keeping everyone safe.Working in Safety, Security & Safeguards gives you the chance to make your mark on some hugely interesting projects.UKNNL does work that nobody else in the sector is doing, and this means we need experts like you to make it possible, whilst keeping everyone safe. Were committed to using nuclear science to benefit society for years to come.This means that you can build a long and successful career here whilst playing a meaningful role in delivering cleaner energy, reducing waste and keeping colleagues and the public out of harms way. As the national laboratory for nuclear fission in the UK, we are harnessing nuclear science to solve some of the worlds biggest challenges. The Measurement and Analysis, instrumentation and in-situ analysis team (M&A-IIA) are involved in development of new technologies for radiometric applications and deployment challenges. The team are looking for an individual to join this growing team to play an important part in allowing NNL to fulfil future commitments and develop into a subject matter expert for future programmes of work and become a technical lead. To join the UKNNL Post Doctorate programme you will have a PhD in radiometric physics, nuclear instrumentation or similar and able to work with engineering, sensor and instrument suppliers. You will have the right to work in the UK and be able to achieve SC level security clearance (this includes but is not limited to identity, employment, financial and criminal record checks plus 5 years worth of UK residency). Main Responsibilities We are developing the next generation of technical experts.Not only will you receive the opportunity to work on challenging and exciting projects, but youll continually learn from skilled and knowledgeable industry experts who are leaders in their field.We will help you become everything you can be, by challenging, stretching, and pushing you to your limits while supporting you every step of the way. You will have the opportunity to work on innovation projects for radiometric instrumentation and customer work for the future, develop your knowledge of radiometric detectors and experience in radiometric systems, and help the Measurement and Analysis, instrumentation and in-situ analysis team deliver decommissioning for the Sellafield site. You will support research and other customer work, experimental design, provide experimental data, data analysis, testing and underpinning evidence for instrumentation and processes. UKNNL recognises that academia and industry are very different environments, our Postdoctoral Development Scheme will smooth the transition whilst supporting you as you take your first steps towards becoming a Subject Matter Expert. Your two-year scheme will provide the opportunity to develop your technical knowledge and skills whilst providing you with an insight into UKNNLs strategy and direction. You will receive an overview of how the company operates and delivers its projects. You will undertake personal development through training aligned to your personal development plan and understand your strengths, weaknesses, and behaviours. You will receive a personal budget to support your development within your field of expertise. From day one youll have a role in a technical team involved in delivering real customer projects.You will have direct sight of the value that your skills and knowledge have to our industry and by extension our society.The Postdoctoral Development Scheme runs alongside your role, providing you the space and skills to develop in a commercial environment whilst helping you decide how to advance your technical expertise. Our two-year programme is designed to give you: An introduction to UKNNL so you understand where we sit in the wider context of the nuclear industry and how we work An introduction to the technical expertise at the core of our business so you understand how your expertise interrelates with our wider technical portfolio A clear pathway of technical development Commercial awareness of the Business Operations of UKNNL Opportunity to network with mid-career professionals and experts Mentoring to achieve chartered status with your chosen professional body A choice of development activities tailored to you and your career aspirations Membership of a cohort of early career professionals to provide support in developing within the company The support of a dedicated early careers team and our strong, thriving early careers community. You will be based at our Central Laboratory, the most modern and advanced facility of its kind in the world. On the doorstep of the Lake District National Park,our Sellafield site offer you the opportunity to work with incredible people on extraordinary projects whilst enjoying some of the most unique and beautiful landscapes the UK has to offer, providing an excellent quality of life. This role allows for hybrid working with the flexibility to work from home on some of your working days. As part of the selection process for the Post Doctorate programme you will complete a Technical Interview against the skills and competencies required for this role. Why join us? UKNNL isnt just a place where you can do career-defining work that makes a real-world impact. Its also a place where youll feel appreciated and valued. Were creating an inclusive workplace where everyone is free to be themselves and feel like they belong.We put your wellbeing first, we push you to reach your potential, and we do everything possible to help you feel safe, supported and inspired. We also offer a range of employee benefits: Sector leading Family-Focused Policies: celebrate life events, including enhanced maternity and paternity leave and a week off for your marriage. UKNNL offers attractive pension plans. If you contribute 5%, UKNNL contributes 15%. Alternatively, if you choose not to contribute (0%), UKNNL will still contribute 10%. Annual Leave: Benefit from 25.5 days of leave, plus 4 extra days to be taken during Christmas shutdown, plus Bank Holidays. Reduced gym membership with discounts of up to 25% from 3,700 gym and leisure providers across the UK Company Bonus: Be rewarded for your contributions. Learning Opportunities: Enhance your skills through excellent development programmes. Employee Assistance: Access support for personal and professional challenges. Cycle to Work: Stay active and eco-friendly. Life Assurance: Ensure peace of mind for you and your loved ones. Enhanced Sick Pay Benefits: Receive support during illness or injury. Access to Mydiscounts which has a range of special offers and discounts from more than 200 suppliers, including medical insurance and dental insurance. Health Care: Health savings plan which allows you to claim money back on visits to the dentist, optician and/or physiotherapist (limits apply). About The Company UKNNL is an incredible place to work. A place where people do things that have never been done before. A place where people push boundaries to further themselves, the business and society as a whole. This is a place where personal and professional opportunities are limitless.If you want to change the world, if you want to tackle climate change, if you want to help advance medical science, if you want to help put things in space, if you want to answer the big questions, if you want to work with extraordinary materials, if you want to meet great people, learn new skills, challenge yourself, work flexibly, and build a long successful career with the power to make a real impact you can do it all here. Equality, Diversity and Inclusion UKNNL has a vision for Equality, Diversity and Inclusivity (ED&I) where UKNNL aims to be an inclusive workplace that attracts diverse talent through transparent and equal policies and procedures, providing reasonable adjustments as appropriate.We want you and the diverse mix of people that we employ, customers that we service and stakeholders that we influence to feel valued.We encourage a workplace culture where everyone can thrive with a sense of belonging and the ability to access to workplace in a way which works for you. Recruitment Agency Notice We operate a strict Preferred Supplier List (PSL) for the provision of recruitment services. Only agencies on our PSL may provide CVs and only when the role is released to them by our recruitment team. We will not accept unsolicited CVs from suppliers not currently on our PSL. We explicitly reserve the right to add candidate details from unsolicited CVs from non-PSL agencies into our own candidate database and to pursue/hire such candidate(s) without any obligation, financial or otherwise, to the agency concerned. JBRP1_UKTJ
Feb 20, 2025
Full time
Job Description This is where your skills play a critical role in keeping everyone safe.Working in Safety, Security & Safeguards gives you the chance to make your mark on some hugely interesting projects.UKNNL does work that nobody else in the sector is doing, and this means we need experts like you to make it possible, whilst keeping everyone safe. Were committed to using nuclear science to benefit society for years to come.This means that you can build a long and successful career here whilst playing a meaningful role in delivering cleaner energy, reducing waste and keeping colleagues and the public out of harms way. As the national laboratory for nuclear fission in the UK, we are harnessing nuclear science to solve some of the worlds biggest challenges. The Measurement and Analysis, instrumentation and in-situ analysis team (M&A-IIA) are involved in development of new technologies for radiometric applications and deployment challenges. The team are looking for an individual to join this growing team to play an important part in allowing NNL to fulfil future commitments and develop into a subject matter expert for future programmes of work and become a technical lead. To join the UKNNL Post Doctorate programme you will have a PhD in radiometric physics, nuclear instrumentation or similar and able to work with engineering, sensor and instrument suppliers. You will have the right to work in the UK and be able to achieve SC level security clearance (this includes but is not limited to identity, employment, financial and criminal record checks plus 5 years worth of UK residency). Main Responsibilities We are developing the next generation of technical experts.Not only will you receive the opportunity to work on challenging and exciting projects, but youll continually learn from skilled and knowledgeable industry experts who are leaders in their field.We will help you become everything you can be, by challenging, stretching, and pushing you to your limits while supporting you every step of the way. You will have the opportunity to work on innovation projects for radiometric instrumentation and customer work for the future, develop your knowledge of radiometric detectors and experience in radiometric systems, and help the Measurement and Analysis, instrumentation and in-situ analysis team deliver decommissioning for the Sellafield site. You will support research and other customer work, experimental design, provide experimental data, data analysis, testing and underpinning evidence for instrumentation and processes. UKNNL recognises that academia and industry are very different environments, our Postdoctoral Development Scheme will smooth the transition whilst supporting you as you take your first steps towards becoming a Subject Matter Expert. Your two-year scheme will provide the opportunity to develop your technical knowledge and skills whilst providing you with an insight into UKNNLs strategy and direction. You will receive an overview of how the company operates and delivers its projects. You will undertake personal development through training aligned to your personal development plan and understand your strengths, weaknesses, and behaviours. You will receive a personal budget to support your development within your field of expertise. From day one youll have a role in a technical team involved in delivering real customer projects.You will have direct sight of the value that your skills and knowledge have to our industry and by extension our society.The Postdoctoral Development Scheme runs alongside your role, providing you the space and skills to develop in a commercial environment whilst helping you decide how to advance your technical expertise. Our two-year programme is designed to give you: An introduction to UKNNL so you understand where we sit in the wider context of the nuclear industry and how we work An introduction to the technical expertise at the core of our business so you understand how your expertise interrelates with our wider technical portfolio A clear pathway of technical development Commercial awareness of the Business Operations of UKNNL Opportunity to network with mid-career professionals and experts Mentoring to achieve chartered status with your chosen professional body A choice of development activities tailored to you and your career aspirations Membership of a cohort of early career professionals to provide support in developing within the company The support of a dedicated early careers team and our strong, thriving early careers community. You will be based at our Central Laboratory, the most modern and advanced facility of its kind in the world. On the doorstep of the Lake District National Park,our Sellafield site offer you the opportunity to work with incredible people on extraordinary projects whilst enjoying some of the most unique and beautiful landscapes the UK has to offer, providing an excellent quality of life. This role allows for hybrid working with the flexibility to work from home on some of your working days. As part of the selection process for the Post Doctorate programme you will complete a Technical Interview against the skills and competencies required for this role. Why join us? UKNNL isnt just a place where you can do career-defining work that makes a real-world impact. Its also a place where youll feel appreciated and valued. Were creating an inclusive workplace where everyone is free to be themselves and feel like they belong.We put your wellbeing first, we push you to reach your potential, and we do everything possible to help you feel safe, supported and inspired. We also offer a range of employee benefits: Sector leading Family-Focused Policies: celebrate life events, including enhanced maternity and paternity leave and a week off for your marriage. UKNNL offers attractive pension plans. If you contribute 5%, UKNNL contributes 15%. Alternatively, if you choose not to contribute (0%), UKNNL will still contribute 10%. Annual Leave: Benefit from 25.5 days of leave, plus 4 extra days to be taken during Christmas shutdown, plus Bank Holidays. Reduced gym membership with discounts of up to 25% from 3,700 gym and leisure providers across the UK Company Bonus: Be rewarded for your contributions. Learning Opportunities: Enhance your skills through excellent development programmes. Employee Assistance: Access support for personal and professional challenges. Cycle to Work: Stay active and eco-friendly. Life Assurance: Ensure peace of mind for you and your loved ones. Enhanced Sick Pay Benefits: Receive support during illness or injury. Access to Mydiscounts which has a range of special offers and discounts from more than 200 suppliers, including medical insurance and dental insurance. Health Care: Health savings plan which allows you to claim money back on visits to the dentist, optician and/or physiotherapist (limits apply). About The Company UKNNL is an incredible place to work. A place where people do things that have never been done before. A place where people push boundaries to further themselves, the business and society as a whole. This is a place where personal and professional opportunities are limitless.If you want to change the world, if you want to tackle climate change, if you want to help advance medical science, if you want to help put things in space, if you want to answer the big questions, if you want to work with extraordinary materials, if you want to meet great people, learn new skills, challenge yourself, work flexibly, and build a long successful career with the power to make a real impact you can do it all here. Equality, Diversity and Inclusion UKNNL has a vision for Equality, Diversity and Inclusivity (ED&I) where UKNNL aims to be an inclusive workplace that attracts diverse talent through transparent and equal policies and procedures, providing reasonable adjustments as appropriate.We want you and the diverse mix of people that we employ, customers that we service and stakeholders that we influence to feel valued.We encourage a workplace culture where everyone can thrive with a sense of belonging and the ability to access to workplace in a way which works for you. Recruitment Agency Notice We operate a strict Preferred Supplier List (PSL) for the provision of recruitment services. Only agencies on our PSL may provide CVs and only when the role is released to them by our recruitment team. We will not accept unsolicited CVs from suppliers not currently on our PSL. We explicitly reserve the right to add candidate details from unsolicited CVs from non-PSL agencies into our own candidate database and to pursue/hire such candidate(s) without any obligation, financial or otherwise, to the agency concerned. JBRP1_UKTJ
Barts Cancer Institute , Queen Mary University London
Postdoctoral Research Assistant
Barts Cancer Institute , Queen Mary University London
About the Role Postdoctoral Research Assistant to join Dr Gallipoli's team (). We study the biological mechanisms underpinning myeloid leukaemia development, progression and therapy resistance with a strong focus on the role of metabolism (Dembitz, Leukemia 2024;Woodley, Nature Communication 2023&Gallipoli, Blood 2018). The successful applicant will investigate how microenvironmental and organismal metabolism affects leukemia cell intrinsic targetable dependencies with the aim to improve current therapeutics efficacy. Informal enquiries are highly encouraged. About You We are seeking highly-motivated researchers holding or near completion of a PhD in a relevant biological or life sciences subject. The ability to develop independent insights into the project, solve complex problems and willingness to work flexibly within a team to achieve the project demands are needed. Experience with flow cytometry, primary cell culture, molecular biology, animal work, metabolic/transcriptional profiling is highly desirable. About Institute The Barts Cancer Institute (BCI) is a Cancer Research UK Centre of Excellence whose work aims to transform the lives of those with and at risk of cancer through innovative research in the laboratory, in patients and in populations. It is one of six institutes within The Faculty of Medicine and Dentistry (FMD) BCI is internationally renowned in many areas of cancer research and it combines ground-breaking basic research with the expertise of clinicians and clinician scientists from the Centre for Experimental Cancer Medicine and the Barts NHS Trust to achieve improvements in cancer patient care. BCI is also a partner in the CRUK City of London Major Centre (together with UCL, Kings and the Francis Crick Institute) which is a Centre of Excellence in Biotherapeutics. BCI is committed in supporting and developing future cancer researchers through its extensive postgraduate training. About Queen Mary At Queen Mary University of London, we believe that a diversity of ideas helps us achieve the previously unthinkable. Throughout our history, we've fostered social justice and improved lives through academic excellence. And we continue to live and breathe this spirit today, not because it's simply 'the right thing to do' but for what it helps us achieve and the intellectual brilliance it delivers. We continue to embrace diversity of thought and opinion in everything we do, in the belief that when views collide, disciplines interact, and perspectives intersect, truly original thought takes form. Benefits We offer competitive salaries, access to a generous pension scheme, 30 days' leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities. The post is based at the Centre for Haemato-Oncology, Barts Cancer Institute. It is full time, fixed term for 12 months, with an expected start date of April 2025. The starting salary will be Grade 4 (SP 26-33), in the range of £38,082 - £45,622 per annum, inclusive of London Allowance. Queen Mary's commitment to our diverse and inclusive community is embedded in our appointments processes. Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly.
Feb 19, 2025
Full time
About the Role Postdoctoral Research Assistant to join Dr Gallipoli's team (). We study the biological mechanisms underpinning myeloid leukaemia development, progression and therapy resistance with a strong focus on the role of metabolism (Dembitz, Leukemia 2024;Woodley, Nature Communication 2023&Gallipoli, Blood 2018). The successful applicant will investigate how microenvironmental and organismal metabolism affects leukemia cell intrinsic targetable dependencies with the aim to improve current therapeutics efficacy. Informal enquiries are highly encouraged. About You We are seeking highly-motivated researchers holding or near completion of a PhD in a relevant biological or life sciences subject. The ability to develop independent insights into the project, solve complex problems and willingness to work flexibly within a team to achieve the project demands are needed. Experience with flow cytometry, primary cell culture, molecular biology, animal work, metabolic/transcriptional profiling is highly desirable. About Institute The Barts Cancer Institute (BCI) is a Cancer Research UK Centre of Excellence whose work aims to transform the lives of those with and at risk of cancer through innovative research in the laboratory, in patients and in populations. It is one of six institutes within The Faculty of Medicine and Dentistry (FMD) BCI is internationally renowned in many areas of cancer research and it combines ground-breaking basic research with the expertise of clinicians and clinician scientists from the Centre for Experimental Cancer Medicine and the Barts NHS Trust to achieve improvements in cancer patient care. BCI is also a partner in the CRUK City of London Major Centre (together with UCL, Kings and the Francis Crick Institute) which is a Centre of Excellence in Biotherapeutics. BCI is committed in supporting and developing future cancer researchers through its extensive postgraduate training. About Queen Mary At Queen Mary University of London, we believe that a diversity of ideas helps us achieve the previously unthinkable. Throughout our history, we've fostered social justice and improved lives through academic excellence. And we continue to live and breathe this spirit today, not because it's simply 'the right thing to do' but for what it helps us achieve and the intellectual brilliance it delivers. We continue to embrace diversity of thought and opinion in everything we do, in the belief that when views collide, disciplines interact, and perspectives intersect, truly original thought takes form. Benefits We offer competitive salaries, access to a generous pension scheme, 30 days' leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities. The post is based at the Centre for Haemato-Oncology, Barts Cancer Institute. It is full time, fixed term for 12 months, with an expected start date of April 2025. The starting salary will be Grade 4 (SP 26-33), in the range of £38,082 - £45,622 per annum, inclusive of London Allowance. Queen Mary's commitment to our diverse and inclusive community is embedded in our appointments processes. Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly.
Postdoctoral Scientist
Vetvaccnet Guildford, Surrey
The Pirbright Institute delivers world-leading research to understand, predict, detect and respond to viral disease outbreaks. We study viruses of livestock that are endemic and exotic to the UK, including zoonotic viruses, by using the most advanced tools and technologies to understand host-pathogen interactions in animals and arthropod vectors. Our major strength in understanding the immune systems of livestock provides a platform to control current diseases and respond to emerging threats. Our Institute is made up of a dynamic and vibrant community of staff covering a diverse set of chosen fields, backgrounds and experience. We all play a crucial role in furthering the Institute's aspirations, advancing the frontiers of science and knowledge through our excellent scientific research, knowledge sharing and contribution; with a real focus in improving the world in which we live. Our outlook is always balanced by our strong sense of purpose, values and behaviours and an unwavering commitment to a 'one Institute' approach. Organisation position and purpose The Pirbright Institute is seeking a highly motivated Postdoctoral Scientist to join Professor Simon Graham's research group as part of an international team tackling Nipah virus, a high-priority zoonotic pathogen. This role is funded through the UKRI-Southeast Asia Collaboration on Infectious Diseases and offers an exciting opportunity to contribute to the development of next-generation vaccines and therapeutics. About the project: Titled "DNA-launched Nipah virus vaccines and therapeutics," this project aims to leverage our innovative DNA-delivery platform to create effective, affordable, and scalable interventions against Nipah virus. Our cutting-edge polymer/peptide nano-formulation technology enables efficient DNA vector delivery, presenting a promising and deployable vaccination and treatment strategy. The project is a collaboration between The Pirbright Institute, the University of Nottingham (UK), and the University of Malaya (Malaysia) and aims to generate the crucial preclinical efficacy data needed for further clinical translation. Professor Simon Graham will serve as the UK Project Lead and direct line manager for the postholder. This is a fantastic opportunity for a postdoctoral scientist passionate about virology, immunology, and translational research to make a tangible impact in global infectious disease control. Main duties and responsibilities: Preclinical Evaluation of DNA-Vectored Therapeutics & Vaccines Conduct pharmacokinetic studies on DNA-vectored therapeutic monoclonal antibodies and assess the immunogenicity of DNA-vectored vaccines in mice and pigs. Produce and purify key research materials, including recombinant Nipah virus glycoproteins, monoclonal antibodies, and pseudo viruses. Coordinate animal studies in collaboration with project partners and contract research organizations, ensuring adherence to study protocols. Analyse antibody responses using pseudovirus neutralization assays and ELISA techniques. Assess T cell responses through IFN-γ ELISpot assays and flow cytometric analysis. Contribute to the development and optimization of novel techniques and methodologies for vaccine response analysis. Collaborative Research & Project Contributions Support the isolation of novel therapeutic monoclonal antibodies from human Nipah virus survivors by providing purified recombinant glycoproteins. Present research updates at monthly consortium meetings and collaborate effectively with international research partners. Disseminate findings by preparing high-quality, peer-reviewed manuscripts and delivering presentations at scientific conferences. Maintain comprehensive health, safety, and biosecurity documentation to ensure a safe research environment. Assist in lab management tasks, including ordering supplies, maintaining equipment, and overseeing sample inventories. Due to the nature of the work we do, all successful applicants will be required to go through a comprehensive screening process including reference and qualification checks, financial and security clearances. Essential/Desirable requirements A PhD or equivalent in a relevant branch of biosciences An excellent record of research productivity, relative to experience Experience of recombinant protein and/or monoclonal antibody expression and purification Experience in immunology including analysis of antibody responses e.g. ELISAs and virus neutralisation assays and T cell responses e.g., flow cytometry Evidence of excellent oral and written communication skills Experience of vaccine/therapeutic antibody R&D Experience of working with large animals Experience of working with viruses Experience of working in international research consortia What we offer Generous Group Personal Pension Scheme and life cover (subject to age and earnings) 25 days annual leave per annum, pro rata, plus 10.5 public and privilege days Buy and sell annual leave Option to carry over up to two weeks annual leave Pirbright gym with subsidised membership Pirbright social club Pirbright Lifestyle Hub (employee discount site) Cycle to work Subsidised employee restaurant Childcare allowance Free onsite parking Electric car charging facilities Due to the high volume of applications we receive, if you have not heard from us within one month from closing date of the vacancy, then please contact us on for an update.
Feb 18, 2025
Full time
The Pirbright Institute delivers world-leading research to understand, predict, detect and respond to viral disease outbreaks. We study viruses of livestock that are endemic and exotic to the UK, including zoonotic viruses, by using the most advanced tools and technologies to understand host-pathogen interactions in animals and arthropod vectors. Our major strength in understanding the immune systems of livestock provides a platform to control current diseases and respond to emerging threats. Our Institute is made up of a dynamic and vibrant community of staff covering a diverse set of chosen fields, backgrounds and experience. We all play a crucial role in furthering the Institute's aspirations, advancing the frontiers of science and knowledge through our excellent scientific research, knowledge sharing and contribution; with a real focus in improving the world in which we live. Our outlook is always balanced by our strong sense of purpose, values and behaviours and an unwavering commitment to a 'one Institute' approach. Organisation position and purpose The Pirbright Institute is seeking a highly motivated Postdoctoral Scientist to join Professor Simon Graham's research group as part of an international team tackling Nipah virus, a high-priority zoonotic pathogen. This role is funded through the UKRI-Southeast Asia Collaboration on Infectious Diseases and offers an exciting opportunity to contribute to the development of next-generation vaccines and therapeutics. About the project: Titled "DNA-launched Nipah virus vaccines and therapeutics," this project aims to leverage our innovative DNA-delivery platform to create effective, affordable, and scalable interventions against Nipah virus. Our cutting-edge polymer/peptide nano-formulation technology enables efficient DNA vector delivery, presenting a promising and deployable vaccination and treatment strategy. The project is a collaboration between The Pirbright Institute, the University of Nottingham (UK), and the University of Malaya (Malaysia) and aims to generate the crucial preclinical efficacy data needed for further clinical translation. Professor Simon Graham will serve as the UK Project Lead and direct line manager for the postholder. This is a fantastic opportunity for a postdoctoral scientist passionate about virology, immunology, and translational research to make a tangible impact in global infectious disease control. Main duties and responsibilities: Preclinical Evaluation of DNA-Vectored Therapeutics & Vaccines Conduct pharmacokinetic studies on DNA-vectored therapeutic monoclonal antibodies and assess the immunogenicity of DNA-vectored vaccines in mice and pigs. Produce and purify key research materials, including recombinant Nipah virus glycoproteins, monoclonal antibodies, and pseudo viruses. Coordinate animal studies in collaboration with project partners and contract research organizations, ensuring adherence to study protocols. Analyse antibody responses using pseudovirus neutralization assays and ELISA techniques. Assess T cell responses through IFN-γ ELISpot assays and flow cytometric analysis. Contribute to the development and optimization of novel techniques and methodologies for vaccine response analysis. Collaborative Research & Project Contributions Support the isolation of novel therapeutic monoclonal antibodies from human Nipah virus survivors by providing purified recombinant glycoproteins. Present research updates at monthly consortium meetings and collaborate effectively with international research partners. Disseminate findings by preparing high-quality, peer-reviewed manuscripts and delivering presentations at scientific conferences. Maintain comprehensive health, safety, and biosecurity documentation to ensure a safe research environment. Assist in lab management tasks, including ordering supplies, maintaining equipment, and overseeing sample inventories. Due to the nature of the work we do, all successful applicants will be required to go through a comprehensive screening process including reference and qualification checks, financial and security clearances. Essential/Desirable requirements A PhD or equivalent in a relevant branch of biosciences An excellent record of research productivity, relative to experience Experience of recombinant protein and/or monoclonal antibody expression and purification Experience in immunology including analysis of antibody responses e.g. ELISAs and virus neutralisation assays and T cell responses e.g., flow cytometry Evidence of excellent oral and written communication skills Experience of vaccine/therapeutic antibody R&D Experience of working with large animals Experience of working with viruses Experience of working in international research consortia What we offer Generous Group Personal Pension Scheme and life cover (subject to age and earnings) 25 days annual leave per annum, pro rata, plus 10.5 public and privilege days Buy and sell annual leave Option to carry over up to two weeks annual leave Pirbright gym with subsidised membership Pirbright social club Pirbright Lifestyle Hub (employee discount site) Cycle to work Subsidised employee restaurant Childcare allowance Free onsite parking Electric car charging facilities Due to the high volume of applications we receive, if you have not heard from us within one month from closing date of the vacancy, then please contact us on for an update.
4 year Postdoctoral Project Research Scientist
WORC Community a Caterpillar Hill Limited
4 year Postdoctoral Project Research Scientist With Professor Charles Swanton Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute. The Cancer Evolution and Genome Instability lab is studying how cancers evolve in the body to spread and become resistant to therapy and finding new ways to treat them more effectively. In recent years it has become clear that every tumour is made up of many different groups of cancer cells, each with their own unique genetic makeup but all related to each other. Some groups of tumour cells develop resistance to treatments such as chemotherapy, immunotherapy, radiotherapy, and targeted therapy, meaning that when the cancer comes back it is harder to treat. Thank you for joining us here at WORC! This platform has the sole purpose of bringing Organoid and Organ-on-a-chip researchers together! Easily connect, share content, ideas, and experiences in this transformative area of science. The idea for this community came after speaking with many of you expressing the need for joined-up thinking and making long-lasting connections.
Feb 17, 2025
Full time
4 year Postdoctoral Project Research Scientist With Professor Charles Swanton Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute. The Cancer Evolution and Genome Instability lab is studying how cancers evolve in the body to spread and become resistant to therapy and finding new ways to treat them more effectively. In recent years it has become clear that every tumour is made up of many different groups of cancer cells, each with their own unique genetic makeup but all related to each other. Some groups of tumour cells develop resistance to treatments such as chemotherapy, immunotherapy, radiotherapy, and targeted therapy, meaning that when the cancer comes back it is harder to treat. Thank you for joining us here at WORC! This platform has the sole purpose of bringing Organoid and Organ-on-a-chip researchers together! Easily connect, share content, ideas, and experiences in this transformative area of science. The idea for this community came after speaking with many of you expressing the need for joined-up thinking and making long-lasting connections.
The Francis Crick Institute
Postdoctoral Fellow- Kohl lab
The Francis Crick Institute
Postdoctoral Fellow Details of the role: This is a full-time, fixed term (4 years) position on Crick terms and conditions of employment Application closing date: 23rd February 2025 About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role We are seeking a highly motivated candidate to lead a project exploring how internal state changes influence neuronal and circuit-level information processing in brain-wide networks underlying instinctive behaviours. You will use advanced optical and electrophysiological recordings in behaving mice to investigate how reproductive state shapes information processing in genetically identified neurons and circuits. This multidisciplinary project will benefit from close collaboration with leading systems neuroscience groups at the Crick, offering a dynamic and supportive research environment. If you have a PhD in Neuroscience or a related field, this may be a perfect opportunity for you to join the Kohl lab. Our team currently includes three postdocs, four PhD students, three research scientists, and one MSc student. We are committed to maintaining a supportive and collaborative research environment, and we particularly value collegiality and open scientific discussion. What you will be doing As a Postdoctoral Fellow at the Crick, you will: Postdoctoral Fellows are expected to lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators), and guide PhD students in their research. The ability to work in a team is essential. Please direct informal enquiries to . About you You will bring Essential PhD in Neuroscience or a related field or in the final stages of PhD submission Good knowledge and experience in in vivo calcium imaging or electrophysiology Experience in data analysis in Python or MATLAB Track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings Desirable Experience in rodent models Very good quantitative and data analysis skills To see the complete Job Description click here for more info! To see more about role/team click here . About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here. What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure with performance-linked progression. Find out what benefits the Crick has to offer: For more information on our great pay and benefits package please click here: Equality, Diversity & Inclusion: We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level. Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute's success. The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment and it is our aim to ensure that these principles are reflected and implemented in all strategies, policies and practices. Read more on our website:
Feb 06, 2025
Full time
Postdoctoral Fellow Details of the role: This is a full-time, fixed term (4 years) position on Crick terms and conditions of employment Application closing date: 23rd February 2025 About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role We are seeking a highly motivated candidate to lead a project exploring how internal state changes influence neuronal and circuit-level information processing in brain-wide networks underlying instinctive behaviours. You will use advanced optical and electrophysiological recordings in behaving mice to investigate how reproductive state shapes information processing in genetically identified neurons and circuits. This multidisciplinary project will benefit from close collaboration with leading systems neuroscience groups at the Crick, offering a dynamic and supportive research environment. If you have a PhD in Neuroscience or a related field, this may be a perfect opportunity for you to join the Kohl lab. Our team currently includes three postdocs, four PhD students, three research scientists, and one MSc student. We are committed to maintaining a supportive and collaborative research environment, and we particularly value collegiality and open scientific discussion. What you will be doing As a Postdoctoral Fellow at the Crick, you will: Postdoctoral Fellows are expected to lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators), and guide PhD students in their research. The ability to work in a team is essential. Please direct informal enquiries to . About you You will bring Essential PhD in Neuroscience or a related field or in the final stages of PhD submission Good knowledge and experience in in vivo calcium imaging or electrophysiology Experience in data analysis in Python or MATLAB Track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings Desirable Experience in rodent models Very good quantitative and data analysis skills To see the complete Job Description click here for more info! To see more about role/team click here . About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here. What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure with performance-linked progression. Find out what benefits the Crick has to offer: For more information on our great pay and benefits package please click here: Equality, Diversity & Inclusion: We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level. Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute's success. The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment and it is our aim to ensure that these principles are reflected and implemented in all strategies, policies and practices. Read more on our website:

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