Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 19, 2025
Full time
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 19, 2025
Full time
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Jun 19, 2025
Full time
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 19, 2025
Full time
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Jun 19, 2025
Full time
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 19, 2025
Full time
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Jun 19, 2025
Full time
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 19, 2025
Full time
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
CK Group are recruiting for a Research & Development Scientist, on behalf of a medical diagnostic company. This role will be based at their site in Gateshead and is a permanent role, with Mon-Fri day time working hours. This vacancy is in the Capillary Electrophoresis Research and Development Department and is the opportunity to join a small, high performance team, developing and supporting the next generation of CE assays and associated software. The candidate would be a highly motivated and self-reliant person, with a science background and ideally 2-3 years experience within the IVD industry. Responsibilities: Take receipt of new projects for the development of capillary electrophoresis tests. Identify deliverables and schedules for new work requests and assist the Senior R&D Scientist with resource allocation. Compile technical documentation to strict regulatory standards. Investigate and troubleshoot the cause of poor product or software performance. Instigate, create, review and maintain Quality System Procedures relating to product validation and verification. Identify, report, and log any bugs found within the software to the Software Department. Test all patches released by the Software Department containing bug fixes and improvements. Complete all software testing prior to customer release. Maintain all relevant patch and software documentation throughout the development process. Update and test Methods Files prior to customer release. Test Firmware releases prior to customer release. Maintain CE Product Technical Files. To maintain the R&D department including management of stock levels and ordering of laboratory supplies. Your Background: B.Sc. or equivalent in Life Sciences or Chemistry. A minimum of 2-3 years post-graduate laboratory/R&D experience is required and experience within the IVD industry would be desirable. Experience of analytical techniques or automated analysers would be an advantage. Familiar with good laboratory practice. Experience of working to IVD or IVDR standards would be an advantage. Advanced writing skills, with the ability to produce coherent and accurate reports. Some knowledge/interest in Capillary Electrophoresis. Excellent time management and organisational skills. Ability to priority plan. Able to communicate well with all personnel within the company. Competent in the use of the Internet and Microsoft Windows programs including Word, Excel, Power Point, and other statistical analysis software. Apply: It is essential all applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDLS
Jun 19, 2025
Full time
CK Group are recruiting for a Research & Development Scientist, on behalf of a medical diagnostic company. This role will be based at their site in Gateshead and is a permanent role, with Mon-Fri day time working hours. This vacancy is in the Capillary Electrophoresis Research and Development Department and is the opportunity to join a small, high performance team, developing and supporting the next generation of CE assays and associated software. The candidate would be a highly motivated and self-reliant person, with a science background and ideally 2-3 years experience within the IVD industry. Responsibilities: Take receipt of new projects for the development of capillary electrophoresis tests. Identify deliverables and schedules for new work requests and assist the Senior R&D Scientist with resource allocation. Compile technical documentation to strict regulatory standards. Investigate and troubleshoot the cause of poor product or software performance. Instigate, create, review and maintain Quality System Procedures relating to product validation and verification. Identify, report, and log any bugs found within the software to the Software Department. Test all patches released by the Software Department containing bug fixes and improvements. Complete all software testing prior to customer release. Maintain all relevant patch and software documentation throughout the development process. Update and test Methods Files prior to customer release. Test Firmware releases prior to customer release. Maintain CE Product Technical Files. To maintain the R&D department including management of stock levels and ordering of laboratory supplies. Your Background: B.Sc. or equivalent in Life Sciences or Chemistry. A minimum of 2-3 years post-graduate laboratory/R&D experience is required and experience within the IVD industry would be desirable. Experience of analytical techniques or automated analysers would be an advantage. Familiar with good laboratory practice. Experience of working to IVD or IVDR standards would be an advantage. Advanced writing skills, with the ability to produce coherent and accurate reports. Some knowledge/interest in Capillary Electrophoresis. Excellent time management and organisational skills. Ability to priority plan. Able to communicate well with all personnel within the company. Competent in the use of the Internet and Microsoft Windows programs including Word, Excel, Power Point, and other statistical analysis software. Apply: It is essential all applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDLS
Job Title: Sustainability Science Leader - Life Cycle Assessment Location: Colworth Science Park Unilever is seeking a Sustainability Science Leader to join a team of experts in our Safety, Environmental and Regulatory Science (SERS). This is an exciting opportunity for anyone wishing to use their scientific expertise to make a significant positive impact, whilst working in a supportive, team-based environment. This pivotal role will enable you to work on tackling some of the key global environmental challenges of our time, such as climate change, packaging waste and biodiversity loss. This is a science role requiring deep technical knowledge in life cycle assessment (LCA) and related approaches. It is not an environmental, social and corporate governance (ESG) or Corporate social responsibility (CSR) role. JOB PURPOSE As a Sustainability Science leader in Unilever, your role will be focused on developing science strategy and partnerships as well as, conducting collaborative research to help advance life cycle assessment and related approaches. Science is an international and multi-disciplinary endeavour; you will partner with leading universities, governmental and non-governmental organisations and industrial groups around the world to deliver new methods, models and data. Publication and presentation of research at international conferences will be expected, and there will be opportunities to engage in various technical advocacy activities. Research outcomes will be targeted for industrial application. As such, translation of new scientific approaches into direct business application will be a key part of the role, allowing for improved assessment of Unilever's product portfolio across our business groups (Nutrition, Home Care, Beauty & Wellbeing and Personal Care) to help deliver our ambition to be the global leader in sustainable business. RESPONSIBILITIES Environmental sustainability science strategy development and implementation: ongoingevolution of current research strategy,partnerships, funding mechanisms and dissemination plans. Development of new scientific approaches: deliver new scientific methods relating to life cycle assessment and associated approaches (e.g. spatially and temporally resolved impact assessment, prospective and ex-ante LCA, absolute sustainability, data generation approaches), including writing reports and publications. Application of LCA software and computational approaches (such as Simapro, Gabi, Brightway; Python, R, MATLAB; GIS) to enable cutting-edge LCA approaches to be developed and applied in industry. External engagement with universities, research groups, trade associations and suppliers. ALL ABOUT YOU You'll need to be able to work effectively and with impact in cross-disciplinary teams and in multi-cultural environments and be flexible and willing to adapt within a fast-changing business environment. We would expect the successful candidate to: Have a relevant PhD, ideally with several years of industrial/consulting/post doc experience. Have science leadership experience including development of project proposals and collaborative partnerships as well as a proven track record in project management. Have experience in the development, application and evaluation of Life Cycle Impact Assessment or footprinting methodologies and potentially associated standards, protocols, databases or tools. Ability to communicate complex scientific information and rationales on environmental sustainability to individuals from other disciplines or from non-technical backgrounds as well as via publications. Ability to employ a strategic and growth mindset. Proven track record of leading / working as part of a team. Willingness to explore and learn new approaches and to support others in doing so. If you have the following skills, that's a bonus but not essential: Broader sustainability expertise in any of the following areas: bio-based systems, agriculture, ecosystem services / natural capital, green chemistry, circular economy, industrial ecology. Experience of employing approaches to assess variability and uncertainty in impact assessments. Experience of using Input/Output (I/O) analysis and related methods. Predictive modelling ideally with a focus on sustainable consumption and land system changes, e.g. understanding and experience of using Land Change models (LCM). LOCATION Colworth Park is a vibrant scientific ecosystem with around 800 employees (500 from Unilever R&D) based on site from over 30 nationalities, with 88 PhDs, 8 Professors, 50 apprentices. On site there are various facilities including a restaurant, a nursery and a gym. There are many social and recreational activities to take part in, such as going for a lunchtime walk or run in the beautiful surrounding countryside, the Colworth choir, and netball team to name just a few. London with all of its attractions is a short 40-minute train ride from Bedford. ABOUT SERS We want consumers to be confident that our products are safe for them and their families, and better for the environment. The scientists in Unilever's Safety, Environmental and Regulatory Science (SERS) group play a key role in ensuring that our products are safe and our business is environmentally sustainable. SERS's world-class reputation for safety and sustainability science plays a key role in Unilever achieving its purpose, by working across the business to build safety and environmental sustainability into everything we do; find out how at . ABOUT UNILEVER Unilever is one of the world's leading suppliers of Food, Home and Personal Care products with sales in over 190 countries and reaching 2 billion consumers a day. Unilever has more than 400 brands found in homes around the world, including Dove, Tresemme, Lynx, Lifebuoy, Shea Moisture, Persil, Domestos, Marmite, Graze and Pot Noodle. NOTES About Unilever Unilever is one of the world's leading suppliers of Food, Home and Personal Care products with sales in over 190 countries and reaching 2 billion consumers a day. Unilever has more than 400 brands found in homes around the world, including Dove, Tresemme, Lynx, Lifebuoy, Shea Moisture, Persil, Domestos, Ben & Jerry's, Magnum, Marmite, The Vegetarian Butcher, Graze and Pot Noodle. Faced with the challenge of climate change and the need for human development, we want to move towards a world where everyone can live well and within the natural limits of the planet. That's why our purpose is 'to make sustainable living commonplace' What We Offer Not only do we offer a competitive salary and pension scheme, we also offer an annual bonus, subsidised gym membership, a discounted staff shop and shares. You'll have the opportunity to work directly with our renowned and exciting brands in a flexible and hybrid working environment. Whilst the role is advertised on a full-time basis, we would be happy to discuss possible flexible working options and what this may look like for you. We are a key advocate of wellbeing and offer a variety of support for our people including hubs, programmes and development opportunities. We strive to achieve a family-friendly and inclusive workplace and to, above all, create possibilities for all. Diversity at Unilever is about inclusion, embracing differences, creating possibilities and growing together for better business performance. We embrace diversity in our workforce. This means giving full and fair consideration to all applicants and continuing development of all employees regardless of age, disability, gender reassignment, race, religion or belief, sex, sexual orientation, marriage and civil partnership, and pregnancy and maternity. We are also more than happy to provide reasonable adjustments during our application and interview process to enable you to be present your best self. To find out more, including about our Employee Resource Groups, please click here Equity, Diversity & Inclusion at Unilever Unilever . Recruitment Fraud Cyber criminals advertise fake job adverts with prestigious employers as a way of stealing information or even defrauding individuals out of money. In the most sophisticated cases, they will set up fake websites, which have a similar address to companies like Unilever. They even conduct fake telephone interviews and then offer candidates a role with the proviso they pay a fee for background checks or to cover work visa costs. These types of attacks are becoming more common as more people are looking for employment in the economic climate. How is Unilever tackling this? Many of Unilever's recruitment sites publish a warning to candidates about recruitment fraud. The Cyber Security team also proactively scan for signs of people setting up fake Unilever sites and act to close them down. What can I do? If you become aware of potential recruitment fraud, spot fake Unilever recruitment adverts or fake LinkedIn profiles, report them via Una Live Chat. Unilever does not accept responsibility or liability for any candidates who are financially impacted by recruitment fraud. Your vigilance is key!
Jun 19, 2025
Full time
Job Title: Sustainability Science Leader - Life Cycle Assessment Location: Colworth Science Park Unilever is seeking a Sustainability Science Leader to join a team of experts in our Safety, Environmental and Regulatory Science (SERS). This is an exciting opportunity for anyone wishing to use their scientific expertise to make a significant positive impact, whilst working in a supportive, team-based environment. This pivotal role will enable you to work on tackling some of the key global environmental challenges of our time, such as climate change, packaging waste and biodiversity loss. This is a science role requiring deep technical knowledge in life cycle assessment (LCA) and related approaches. It is not an environmental, social and corporate governance (ESG) or Corporate social responsibility (CSR) role. JOB PURPOSE As a Sustainability Science leader in Unilever, your role will be focused on developing science strategy and partnerships as well as, conducting collaborative research to help advance life cycle assessment and related approaches. Science is an international and multi-disciplinary endeavour; you will partner with leading universities, governmental and non-governmental organisations and industrial groups around the world to deliver new methods, models and data. Publication and presentation of research at international conferences will be expected, and there will be opportunities to engage in various technical advocacy activities. Research outcomes will be targeted for industrial application. As such, translation of new scientific approaches into direct business application will be a key part of the role, allowing for improved assessment of Unilever's product portfolio across our business groups (Nutrition, Home Care, Beauty & Wellbeing and Personal Care) to help deliver our ambition to be the global leader in sustainable business. RESPONSIBILITIES Environmental sustainability science strategy development and implementation: ongoingevolution of current research strategy,partnerships, funding mechanisms and dissemination plans. Development of new scientific approaches: deliver new scientific methods relating to life cycle assessment and associated approaches (e.g. spatially and temporally resolved impact assessment, prospective and ex-ante LCA, absolute sustainability, data generation approaches), including writing reports and publications. Application of LCA software and computational approaches (such as Simapro, Gabi, Brightway; Python, R, MATLAB; GIS) to enable cutting-edge LCA approaches to be developed and applied in industry. External engagement with universities, research groups, trade associations and suppliers. ALL ABOUT YOU You'll need to be able to work effectively and with impact in cross-disciplinary teams and in multi-cultural environments and be flexible and willing to adapt within a fast-changing business environment. We would expect the successful candidate to: Have a relevant PhD, ideally with several years of industrial/consulting/post doc experience. Have science leadership experience including development of project proposals and collaborative partnerships as well as a proven track record in project management. Have experience in the development, application and evaluation of Life Cycle Impact Assessment or footprinting methodologies and potentially associated standards, protocols, databases or tools. Ability to communicate complex scientific information and rationales on environmental sustainability to individuals from other disciplines or from non-technical backgrounds as well as via publications. Ability to employ a strategic and growth mindset. Proven track record of leading / working as part of a team. Willingness to explore and learn new approaches and to support others in doing so. If you have the following skills, that's a bonus but not essential: Broader sustainability expertise in any of the following areas: bio-based systems, agriculture, ecosystem services / natural capital, green chemistry, circular economy, industrial ecology. Experience of employing approaches to assess variability and uncertainty in impact assessments. Experience of using Input/Output (I/O) analysis and related methods. Predictive modelling ideally with a focus on sustainable consumption and land system changes, e.g. understanding and experience of using Land Change models (LCM). LOCATION Colworth Park is a vibrant scientific ecosystem with around 800 employees (500 from Unilever R&D) based on site from over 30 nationalities, with 88 PhDs, 8 Professors, 50 apprentices. On site there are various facilities including a restaurant, a nursery and a gym. There are many social and recreational activities to take part in, such as going for a lunchtime walk or run in the beautiful surrounding countryside, the Colworth choir, and netball team to name just a few. London with all of its attractions is a short 40-minute train ride from Bedford. ABOUT SERS We want consumers to be confident that our products are safe for them and their families, and better for the environment. The scientists in Unilever's Safety, Environmental and Regulatory Science (SERS) group play a key role in ensuring that our products are safe and our business is environmentally sustainable. SERS's world-class reputation for safety and sustainability science plays a key role in Unilever achieving its purpose, by working across the business to build safety and environmental sustainability into everything we do; find out how at . ABOUT UNILEVER Unilever is one of the world's leading suppliers of Food, Home and Personal Care products with sales in over 190 countries and reaching 2 billion consumers a day. Unilever has more than 400 brands found in homes around the world, including Dove, Tresemme, Lynx, Lifebuoy, Shea Moisture, Persil, Domestos, Marmite, Graze and Pot Noodle. NOTES About Unilever Unilever is one of the world's leading suppliers of Food, Home and Personal Care products with sales in over 190 countries and reaching 2 billion consumers a day. Unilever has more than 400 brands found in homes around the world, including Dove, Tresemme, Lynx, Lifebuoy, Shea Moisture, Persil, Domestos, Ben & Jerry's, Magnum, Marmite, The Vegetarian Butcher, Graze and Pot Noodle. Faced with the challenge of climate change and the need for human development, we want to move towards a world where everyone can live well and within the natural limits of the planet. That's why our purpose is 'to make sustainable living commonplace' What We Offer Not only do we offer a competitive salary and pension scheme, we also offer an annual bonus, subsidised gym membership, a discounted staff shop and shares. You'll have the opportunity to work directly with our renowned and exciting brands in a flexible and hybrid working environment. Whilst the role is advertised on a full-time basis, we would be happy to discuss possible flexible working options and what this may look like for you. We are a key advocate of wellbeing and offer a variety of support for our people including hubs, programmes and development opportunities. We strive to achieve a family-friendly and inclusive workplace and to, above all, create possibilities for all. Diversity at Unilever is about inclusion, embracing differences, creating possibilities and growing together for better business performance. We embrace diversity in our workforce. This means giving full and fair consideration to all applicants and continuing development of all employees regardless of age, disability, gender reassignment, race, religion or belief, sex, sexual orientation, marriage and civil partnership, and pregnancy and maternity. We are also more than happy to provide reasonable adjustments during our application and interview process to enable you to be present your best self. To find out more, including about our Employee Resource Groups, please click here Equity, Diversity & Inclusion at Unilever Unilever . Recruitment Fraud Cyber criminals advertise fake job adverts with prestigious employers as a way of stealing information or even defrauding individuals out of money. In the most sophisticated cases, they will set up fake websites, which have a similar address to companies like Unilever. They even conduct fake telephone interviews and then offer candidates a role with the proviso they pay a fee for background checks or to cover work visa costs. These types of attacks are becoming more common as more people are looking for employment in the economic climate. How is Unilever tackling this? Many of Unilever's recruitment sites publish a warning to candidates about recruitment fraud. The Cyber Security team also proactively scan for signs of people setting up fake Unilever sites and act to close them down. What can I do? If you become aware of potential recruitment fraud, spot fake Unilever recruitment adverts or fake LinkedIn profiles, report them via Una Live Chat. Unilever does not accept responsibility or liability for any candidates who are financially impacted by recruitment fraud. Your vigilance is key!
CK Group are working in partnership with Nxera Pharma, to recruit a Membrane Protein Biochemist, to join their Protein Sciences division. This role is ideal for a scientist passionate about GPCRs and biochemistry of membrane proteins. It offers a unique opportunity to contribute to cutting-edge drug discovery in a highly collaborative and innovative environment. Applications are welcomed from candidates with a PhD in Biochemistry, Biophysics or similar, with proven experience in membrane protein expression and purification. Location: Granta Park, Cambridge. About the company: Nxera Pharma (formerly Sosei Heptares) is a technology powered biopharma company, in pursuit of new speciality medicines to improve the lives of patients with unmet needs globally. Their pipeline is focused on addressing major unmet needs in some of the fastest-growing areas of medicine across CNS, GI and immunology, metabolic disorders and rare diseases, and leverages the power of their unique and industry leading GPCR-targeted structure-based drug discovery NxWave platform to provide a sustainable source of best- or first-in-class candidates. In Cambridge UK, Nxera have built outstanding capabilities across their platform, discovery and translational medicine teams, to advance multiple programs from pre-clinical through to early clinical development. About the role: In this role you will focus on the expression and purification of challenging membrane proteins destined for biochemical, biophysical and structural studies to support Nxera s structure-based drug design process. Responsibilities will include: Express and purify membrane proteins for biochemical, biophysical and structural biology applications. Design and engineer membrane protein expression constructs to maximise functional expression in mammalian and insect cell expression systems. Optimise protein expression and fine-tune protein purification workflows to obtain pure, homogeneous and stable membrane proteins. Biochemically and biophysically characterise purified membrane proteins using a range of analytical techniques (fSEC, DLS, SEC-MALS, DSF, FP, etc ). Reconstitute purified membrane proteins in membrane mimetic environments (lipid nanodiscs, liposomes, amphipols, etc ). Assemble and purify homogeneous and stoichiometric multi-component protein complexes. Keep up to date with relevant scientific literature, propose, develop, implement and optimise new methodologies in the fields of membrane protein expression, purification and biochemical characterisation. Prepare and effectively present results (written and oral) to project teams. Demonstrate strong interpersonal skills and collaborate effectively with other Nxera scientists to successfully progress membrane protein targets through the Nxera structure-based drug design pipeline. Maintain detailed and accurate laboratory records. Skills and Experience: A PhD in biochemistry, biophysics or a related discipline Proven molecular biology skills enabling the design and engineering of membrane protein expression constructs tailored to downstream applications. Proficiency in the expression of membrane proteins in mammalian and insect cells expression systems (transfection and transduction-based methods). Practical expertise in optimising purification protocols for membrane proteins. Deep understanding of what constitutes a good membrane protein sample for structural (X-ray crystallography and/or cryo-EM) and biophysical studies (SPR, mass spectrometry). Demonstrable experience in a broad range of biochemical and biophysical techniques. Desirable: Ability to design and interpret protein construct optimisation using in silico methods (e.g. AlphaFold) with wet lab impact. Ability to effectively analyse experimental or predicted structures of membrane proteins (cryoEM, X-ray, in silico ). Experience using molecular graphics software (e.g. Pymol, Chimera, Coot ). Experience with assay development and optimisation for small molecule drug discovery. Experience in the reconstitution of purified membrane proteins in membrane-mimetic environments. What s in it for you? State-of-the-art R&D centre located in the heart of the Cambridge science cluster. Competitive compensation package including discretionary cash bonuses. Eligible for grants of Restricted Stock Units. 26 days annual leave in addition to public holidays. Employer contribution to pension. Private Medical Insurance for employees and family and a cash plan for dental and optical reimbursement. Health and wellbeing benefits including a subsidised individual gym membership. Income protection to cover long term absences due to ill health. Group Death in Service equal to 4x basic annual salary. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence.
Jun 19, 2025
Full time
CK Group are working in partnership with Nxera Pharma, to recruit a Membrane Protein Biochemist, to join their Protein Sciences division. This role is ideal for a scientist passionate about GPCRs and biochemistry of membrane proteins. It offers a unique opportunity to contribute to cutting-edge drug discovery in a highly collaborative and innovative environment. Applications are welcomed from candidates with a PhD in Biochemistry, Biophysics or similar, with proven experience in membrane protein expression and purification. Location: Granta Park, Cambridge. About the company: Nxera Pharma (formerly Sosei Heptares) is a technology powered biopharma company, in pursuit of new speciality medicines to improve the lives of patients with unmet needs globally. Their pipeline is focused on addressing major unmet needs in some of the fastest-growing areas of medicine across CNS, GI and immunology, metabolic disorders and rare diseases, and leverages the power of their unique and industry leading GPCR-targeted structure-based drug discovery NxWave platform to provide a sustainable source of best- or first-in-class candidates. In Cambridge UK, Nxera have built outstanding capabilities across their platform, discovery and translational medicine teams, to advance multiple programs from pre-clinical through to early clinical development. About the role: In this role you will focus on the expression and purification of challenging membrane proteins destined for biochemical, biophysical and structural studies to support Nxera s structure-based drug design process. Responsibilities will include: Express and purify membrane proteins for biochemical, biophysical and structural biology applications. Design and engineer membrane protein expression constructs to maximise functional expression in mammalian and insect cell expression systems. Optimise protein expression and fine-tune protein purification workflows to obtain pure, homogeneous and stable membrane proteins. Biochemically and biophysically characterise purified membrane proteins using a range of analytical techniques (fSEC, DLS, SEC-MALS, DSF, FP, etc ). Reconstitute purified membrane proteins in membrane mimetic environments (lipid nanodiscs, liposomes, amphipols, etc ). Assemble and purify homogeneous and stoichiometric multi-component protein complexes. Keep up to date with relevant scientific literature, propose, develop, implement and optimise new methodologies in the fields of membrane protein expression, purification and biochemical characterisation. Prepare and effectively present results (written and oral) to project teams. Demonstrate strong interpersonal skills and collaborate effectively with other Nxera scientists to successfully progress membrane protein targets through the Nxera structure-based drug design pipeline. Maintain detailed and accurate laboratory records. Skills and Experience: A PhD in biochemistry, biophysics or a related discipline Proven molecular biology skills enabling the design and engineering of membrane protein expression constructs tailored to downstream applications. Proficiency in the expression of membrane proteins in mammalian and insect cells expression systems (transfection and transduction-based methods). Practical expertise in optimising purification protocols for membrane proteins. Deep understanding of what constitutes a good membrane protein sample for structural (X-ray crystallography and/or cryo-EM) and biophysical studies (SPR, mass spectrometry). Demonstrable experience in a broad range of biochemical and biophysical techniques. Desirable: Ability to design and interpret protein construct optimisation using in silico methods (e.g. AlphaFold) with wet lab impact. Ability to effectively analyse experimental or predicted structures of membrane proteins (cryoEM, X-ray, in silico ). Experience using molecular graphics software (e.g. Pymol, Chimera, Coot ). Experience with assay development and optimisation for small molecule drug discovery. Experience in the reconstitution of purified membrane proteins in membrane-mimetic environments. What s in it for you? State-of-the-art R&D centre located in the heart of the Cambridge science cluster. Competitive compensation package including discretionary cash bonuses. Eligible for grants of Restricted Stock Units. 26 days annual leave in addition to public holidays. Employer contribution to pension. Private Medical Insurance for employees and family and a cash plan for dental and optical reimbursement. Health and wellbeing benefits including a subsidised individual gym membership. Income protection to cover long term absences due to ill health. Group Death in Service equal to 4x basic annual salary. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence.
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Jun 19, 2025
Full time
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Overview PepsiCo is looking for an R&D Sensory & Consumer Experience Scientist to join our team in Leicester, UK or Cork, Ireland. Are you passionate about understanding consumers and shaping the future of food and beverage experiences? PepsiCo is seeking a dynamic and strategic Senior Scientist to join our R&D Sensory & Consumer Experience team. In this influential role, you'll lead sensory and consumer research that drives innovation, brand growth, and product excellence across our global portfolio. You'll collaborate with cross-functional teams to translate insights into impactful product design decisions-fueling innovation and transformation across Foods and Beverages. If you're driven by curiosity, thrive in a fast-paced environment, and want to make a global impact, we'd love to hear from you. Responsibilities Strategic Research Leadership: Develop and execute integrated sensory and consumer research plans supporting innovation, brand stewardship, and productivity initiatives. Cross-Functional Collaboration: Partner with R&D, Consumer Insights, and Marketing to align research strategies with business goals and ensure adherence to the TSG process. Global to Local Execution: Adapt and implement global sensory protocols to local markets, driving efficiency and consistency in research practices. Insight Translation: Deliver clear, actionable insights from both qualitative and quantitative research to inform product development and influence senior stakeholders. Capability Building: Mentor and coach peers to elevate research standards and promote best practices across the organization. Vendor & Resource Management: Collaborate with external vendors/partners to ensure high-quality research design and execution aligned with best practices. Qualifications Key Skills/Experience Required: Educational Background: Master's or PhD in Sensory Science, Psychology, Food Science, or a related field. Strong foundation in research design, methodologies, and statistical analysis. Industry Experience: At least 2-3 years (with Master's or PhD) or 5+ years (with Bachelor's) in sensory or consumer research, ideally within FMCG. Research Expertise: Deep knowledge of sensory, qualitative and quantitative testing methods, with a passion for applying cutting-edge consumer science techniques. Business Acumen: Ability to connect technical insights with commercial strategy and broader business objectives. Analytical & Communication Skills: Strong data interpretation skills, with the ability to distill complex findings into compelling narratives for diverse audiences. Digital Fluency: Comfortable with digital tools and systems in a fast-paced, evolving environment. Cultural Agility: Able to work effectively across geographies and cultures, with a collaborative and inclusive mindset. Self-starter, self-motivating - very high drive for results and able to deal with uncertainty and complexity.
Jun 19, 2025
Full time
Overview PepsiCo is looking for an R&D Sensory & Consumer Experience Scientist to join our team in Leicester, UK or Cork, Ireland. Are you passionate about understanding consumers and shaping the future of food and beverage experiences? PepsiCo is seeking a dynamic and strategic Senior Scientist to join our R&D Sensory & Consumer Experience team. In this influential role, you'll lead sensory and consumer research that drives innovation, brand growth, and product excellence across our global portfolio. You'll collaborate with cross-functional teams to translate insights into impactful product design decisions-fueling innovation and transformation across Foods and Beverages. If you're driven by curiosity, thrive in a fast-paced environment, and want to make a global impact, we'd love to hear from you. Responsibilities Strategic Research Leadership: Develop and execute integrated sensory and consumer research plans supporting innovation, brand stewardship, and productivity initiatives. Cross-Functional Collaboration: Partner with R&D, Consumer Insights, and Marketing to align research strategies with business goals and ensure adherence to the TSG process. Global to Local Execution: Adapt and implement global sensory protocols to local markets, driving efficiency and consistency in research practices. Insight Translation: Deliver clear, actionable insights from both qualitative and quantitative research to inform product development and influence senior stakeholders. Capability Building: Mentor and coach peers to elevate research standards and promote best practices across the organization. Vendor & Resource Management: Collaborate with external vendors/partners to ensure high-quality research design and execution aligned with best practices. Qualifications Key Skills/Experience Required: Educational Background: Master's or PhD in Sensory Science, Psychology, Food Science, or a related field. Strong foundation in research design, methodologies, and statistical analysis. Industry Experience: At least 2-3 years (with Master's or PhD) or 5+ years (with Bachelor's) in sensory or consumer research, ideally within FMCG. Research Expertise: Deep knowledge of sensory, qualitative and quantitative testing methods, with a passion for applying cutting-edge consumer science techniques. Business Acumen: Ability to connect technical insights with commercial strategy and broader business objectives. Analytical & Communication Skills: Strong data interpretation skills, with the ability to distill complex findings into compelling narratives for diverse audiences. Digital Fluency: Comfortable with digital tools and systems in a fast-paced, evolving environment. Cultural Agility: Able to work effectively across geographies and cultures, with a collaborative and inclusive mindset. Self-starter, self-motivating - very high drive for results and able to deal with uncertainty and complexity.
Introduction to role Are you ready to make a significant impact in the world of science? As a Resource Lead at AstraZeneca, you will play a crucial role in optimizing resource deployment across AST UK. Your efforts will support in vivo work in Early Oncology and Biopharma, improving efficacy, safety, and discovery initiatives. This dynamic position requires flexibility to work across therapeutic areas and pipelines both within the UK and globally. You will collaborate closely with science leads, section managers, and the Director, Head of Operations, ensuring alignment with strategic objectives. Join us in this exciting journey to drive scientific innovation! Accountabilities Resourcing: Collaborate with AST Science Leads and TA in vivo leads to resolve and coordinate resource requirements (FTE, capabilities) for mid-term planning across vivarium units. Identify potential risks to project delivery, propose mitigation strategies, and escalate issues to the Head of Department (HoD), Science Leads, and Section Managers as needed. Liaise with AST Section managers and in vivo scientists to handle working rotas, including PM and weekend cover. Ensure the timely delivery of animals for study delivery from the facility. Support the development of business cases for workforce, CAPEX, and capital requirements in collaboration with the AST UK Operations team. Organisation Performance: Analyse and evaluate information and help to identify any deficiencies, which may lead to standards falling. Will help to assess the practicalities of implementing new developments and innovations in the use of animals for scientific research. Ensure quality control and accurate reporting of AST UK delivery metrics. Identify and lead delivery optimization projects focused on improving time to delivery, cost efficiency, operational efficiencies, and the 3Rs on a UK level, and supply to global efforts. Mentor and develop staff to enhance their skills and performance. Contribute to the AST UK Scorecard and provide ad hoc support as required. Facility Management and Operations: Implement processes related to access to the animal facility, ensuring secure and efficient operations. Supervise the maintenance and operation of key equipment within the facility to ensure optimal functionality and compliance with regulatory standards. Supervise the implementation of Safety, Health, and Environment (SHE) ways of working in the animal facility, ensuring compliance with safety standards and regulations. Interact with key partners to understand future strategy in respect to laboratory animal science and propose or advise best practices to support the strategy. Participate in meetings, committees or external groups as an advisor on animal-related issues. Essential Skills/Experience Bachelor's degree or equivalent experience in a relevant field such as Life Sciences, Business Administration, or a related subject area. Hands-on experience in vivo, demonstrating familiarity with animal studies and scientific rigour. Proven matrix leadership experience, effectively handling cross-functional project teams. Strong experience in business planning and management. Exceptional organizational, analytical, and problem-solving abilities. Excellent communication and stakeholder engagement skills. A thorough understanding of key milestones in the drug development cycle. Desirable Skills/Experience Experience in operational management with a preference for LEAN methodologies and project management skills. Proven experience in efficiency optimization and cost management projects. Additional qualifications or certifications related to SHE, facilities management, or operational excellence. At AstraZeneca, we are driven by our passion for science. We are committed to making a difference by exploring new frontiers in treating some of the world's most complex diseases. Our inclusive environment fosters collaboration between academia, biotech, and industry experts. By integrating data and technology with scientific innovation, we are poised to achieve groundbreaking breakthroughs that will positively impact billions of patients worldwide. Here, curiosity meets courage as we push boundaries to deliver life-changing medicines. Ready to join us on this exciting journey? Apply now to be part of a team that is transforming healthcare!
Jun 19, 2025
Full time
Introduction to role Are you ready to make a significant impact in the world of science? As a Resource Lead at AstraZeneca, you will play a crucial role in optimizing resource deployment across AST UK. Your efforts will support in vivo work in Early Oncology and Biopharma, improving efficacy, safety, and discovery initiatives. This dynamic position requires flexibility to work across therapeutic areas and pipelines both within the UK and globally. You will collaborate closely with science leads, section managers, and the Director, Head of Operations, ensuring alignment with strategic objectives. Join us in this exciting journey to drive scientific innovation! Accountabilities Resourcing: Collaborate with AST Science Leads and TA in vivo leads to resolve and coordinate resource requirements (FTE, capabilities) for mid-term planning across vivarium units. Identify potential risks to project delivery, propose mitigation strategies, and escalate issues to the Head of Department (HoD), Science Leads, and Section Managers as needed. Liaise with AST Section managers and in vivo scientists to handle working rotas, including PM and weekend cover. Ensure the timely delivery of animals for study delivery from the facility. Support the development of business cases for workforce, CAPEX, and capital requirements in collaboration with the AST UK Operations team. Organisation Performance: Analyse and evaluate information and help to identify any deficiencies, which may lead to standards falling. Will help to assess the practicalities of implementing new developments and innovations in the use of animals for scientific research. Ensure quality control and accurate reporting of AST UK delivery metrics. Identify and lead delivery optimization projects focused on improving time to delivery, cost efficiency, operational efficiencies, and the 3Rs on a UK level, and supply to global efforts. Mentor and develop staff to enhance their skills and performance. Contribute to the AST UK Scorecard and provide ad hoc support as required. Facility Management and Operations: Implement processes related to access to the animal facility, ensuring secure and efficient operations. Supervise the maintenance and operation of key equipment within the facility to ensure optimal functionality and compliance with regulatory standards. Supervise the implementation of Safety, Health, and Environment (SHE) ways of working in the animal facility, ensuring compliance with safety standards and regulations. Interact with key partners to understand future strategy in respect to laboratory animal science and propose or advise best practices to support the strategy. Participate in meetings, committees or external groups as an advisor on animal-related issues. Essential Skills/Experience Bachelor's degree or equivalent experience in a relevant field such as Life Sciences, Business Administration, or a related subject area. Hands-on experience in vivo, demonstrating familiarity with animal studies and scientific rigour. Proven matrix leadership experience, effectively handling cross-functional project teams. Strong experience in business planning and management. Exceptional organizational, analytical, and problem-solving abilities. Excellent communication and stakeholder engagement skills. A thorough understanding of key milestones in the drug development cycle. Desirable Skills/Experience Experience in operational management with a preference for LEAN methodologies and project management skills. Proven experience in efficiency optimization and cost management projects. Additional qualifications or certifications related to SHE, facilities management, or operational excellence. At AstraZeneca, we are driven by our passion for science. We are committed to making a difference by exploring new frontiers in treating some of the world's most complex diseases. Our inclusive environment fosters collaboration between academia, biotech, and industry experts. By integrating data and technology with scientific innovation, we are poised to achieve groundbreaking breakthroughs that will positively impact billions of patients worldwide. Here, curiosity meets courage as we push boundaries to deliver life-changing medicines. Ready to join us on this exciting journey? Apply now to be part of a team that is transforming healthcare!
Job Title: Sustainability Science Leader - Life Cycle Assessment Location: Colworth Science Park Unilever is seeking a Sustainability Science Leader to join a team of experts in our Safety, Environmental and Regulatory Science (SERS). This is an exciting opportunity for anyone wishing to use their scientific expertise to make a significant positive impact, whilst working in a supportive, team-based environment. This pivotal role will enable you to work on tackling some of the key global environmental challenges of our time, such as climate change, packaging waste and biodiversity loss. This is a science role requiring deep technical knowledge in life cycle assessment (LCA) and related approaches. It is not an environmental, social and corporate governance (ESG) or Corporate social responsibility (CSR) role. JOB PURPOSE As a Sustainability Science leader in Unilever, your role will be focused on developing science strategy and partnerships as well as, conducting collaborative research to help advance life cycle assessment and related approaches. Science is an international and multi-disciplinary endeavour; you will partner with leading universities, governmental and non-governmental organisations and industrial groups around the world to deliver new methods, models and data. Publication and presentation of research at international conferences will be expected, and there will be opportunities to engage in various technical advocacy activities. Research outcomes will be targeted for industrial application. As such, translation of new scientific approaches into direct business application will be a key part of the role, allowing for improved assessment of Unilever's product portfolio across our business groups (Nutrition, Home Care, Beauty & Wellbeing and Personal Care) to help deliver our ambition to be the global leader in sustainable business. RESPONSIBILITIES Environmental sustainability science strategy development and implementation: ongoingevolution of current research strategy,partnerships, funding mechanisms and dissemination plans. Development of new scientific approaches: deliver new scientific methods relating to life cycle assessment and associated approaches (e.g. spatially and temporally resolved impact assessment, prospective and ex-ante LCA, absolute sustainability, data generation approaches), including writing reports and publications. Application of LCA software and computational approaches (such as Simapro, Gabi, Brightway; Python, R, MATLAB; GIS) to enable cutting-edge LCA approaches to be developed and applied in industry. External engagement with universities, research groups, trade associations and suppliers. ALL ABOUT YOU You'll need to be able to work effectively and with impact in cross-disciplinary teams and in multi-cultural environments and be flexible and willing to adapt within a fast-changing business environment. We would expect the successful candidate to: Have a relevant PhD, ideally with several years of industrial/consulting/post doc experience. Have science leadership experience including development of project proposals and collaborative partnerships as well as a proven track record in project management. Have experience in the development, application and evaluation of Life Cycle Impact Assessment or footprinting methodologies and potentially associated standards, protocols, databases or tools. Ability to communicate complex scientific information and rationales on environmental sustainability to individuals from other disciplines or from non-technical backgrounds as well as via publications. Ability to employ a strategic and growth mindset. Proven track record of leading / working as part of a team. Willingness to explore and learn new approaches and to support others in doing so. If you have the following skills, that's a bonus but not essential: Broader sustainability expertise in any of the following areas: bio-based systems, agriculture, ecosystem services / natural capital, green chemistry, circular economy, industrial ecology. Experience of employing approaches to assess variability and uncertainty in impact assessments. Experience of using Input/Output (I/O) analysis and related methods. Predictive modelling ideally with a focus on sustainable consumption and land system changes, e.g. understanding and experience of using Land Change models (LCM). LOCATION Colworth Park is a vibrant scientific ecosystem with around 800 employees (500 from Unilever R&D) based on site from over 30 nationalities, with 88 PhDs, 8 Professors, 50 apprentices. On site there are various facilities including a restaurant, a nursery and a gym. There are many social and recreational activities to take part in, such as going for a lunchtime walk or run in the beautiful surrounding countryside, the Colworth choir, and netball team to name just a few. London with all of its attractions is a short 40-minute train ride from Bedford. ABOUT SERS We want consumers to be confident that our products are safe for them and their families, and better for the environment. The scientists in Unilever's Safety, Environmental and Regulatory Science (SERS) group play a key role in ensuring that our products are safe and our business is environmentally sustainable. SERS's world-class reputation for safety and sustainability science plays a key role in Unilever achieving its purpose, by working across the business to build safety and environmental sustainability into everything we do; find out how at . ABOUT UNILEVER Unilever is one of the world's leading suppliers of Food, Home and Personal Care products with sales in over 190 countries and reaching 2 billion consumers a day. Unilever has more than 400 brands found in homes around the world, including Dove, Tresemme, Lynx, Lifebuoy, Shea Moisture, Persil, Domestos, Marmite, Graze and Pot Noodle. NOTES About Unilever Unilever is one of the world's leading suppliers of Food, Home and Personal Care products with sales in over 190 countries and reaching 2 billion consumers a day. Unilever has more than 400 brands found in homes around the world, including Dove, Tresemme, Lynx, Lifebuoy, Shea Moisture, Persil, Domestos, Ben & Jerry's, Magnum, Marmite, The Vegetarian Butcher, Graze and Pot Noodle. Faced with the challenge of climate change and the need for human development, we want to move towards a world where everyone can live well and within the natural limits of the planet. That's why our purpose is 'to make sustainable living commonplace' What We Offer Not only do we offer a competitive salary and pension scheme, we also offer an annual bonus, subsidised gym membership, a discounted staff shop and shares. You'll have the opportunity to work directly with our renowned and exciting brands in a flexible and hybrid working environment. Whilst the role is advertised on a full-time basis, we would be happy to discuss possible flexible working options and what this may look like for you. We are a key advocate of wellbeing and offer a variety of support for our people including hubs, programmes and development opportunities. We strive to achieve a family-friendly and inclusive workplace and to, above all, create possibilities for all. Diversity at Unilever is about inclusion, embracing differences, creating possibilities and growing together for better business performance. We embrace diversity in our workforce. This means giving full and fair consideration to all applicants and continuing development of all employees regardless of age, disability, gender reassignment, race, religion or belief, sex, sexual orientation, marriage and civil partnership, and pregnancy and maternity. We are also more than happy to provide reasonable adjustments during our application and interview process to enable you to be present your best self. To find out more, including about our Employee Resource Groups, please click here Equity, Diversity & Inclusion at Unilever Unilever . Recruitment Fraud Cyber criminals advertise fake job adverts with prestigious employers as a way of stealing information or even defrauding individuals out of money. In the most sophisticated cases, they will set up fake websites, which have a similar address to companies like Unilever. They even conduct fake telephone interviews and then offer candidates a role with the proviso they pay a fee for background checks or to cover work visa costs. These types of attacks are becoming more common as more people are looking for employment in the economic climate. How is Unilever tackling this? Many of Unilever's recruitment sites publish a warning to candidates about recruitment fraud. The Cyber Security team also proactively scan for signs of people setting up fake Unilever sites and act to close them down. What can I do? If you become aware of potential recruitment fraud, spot fake Unilever recruitment adverts or fake LinkedIn profiles, report them via Una Live Chat. Unilever does not accept responsibility or liability for any candidates who are financially impacted by recruitment fraud. Your vigilance is key!
Jun 19, 2025
Full time
Job Title: Sustainability Science Leader - Life Cycle Assessment Location: Colworth Science Park Unilever is seeking a Sustainability Science Leader to join a team of experts in our Safety, Environmental and Regulatory Science (SERS). This is an exciting opportunity for anyone wishing to use their scientific expertise to make a significant positive impact, whilst working in a supportive, team-based environment. This pivotal role will enable you to work on tackling some of the key global environmental challenges of our time, such as climate change, packaging waste and biodiversity loss. This is a science role requiring deep technical knowledge in life cycle assessment (LCA) and related approaches. It is not an environmental, social and corporate governance (ESG) or Corporate social responsibility (CSR) role. JOB PURPOSE As a Sustainability Science leader in Unilever, your role will be focused on developing science strategy and partnerships as well as, conducting collaborative research to help advance life cycle assessment and related approaches. Science is an international and multi-disciplinary endeavour; you will partner with leading universities, governmental and non-governmental organisations and industrial groups around the world to deliver new methods, models and data. Publication and presentation of research at international conferences will be expected, and there will be opportunities to engage in various technical advocacy activities. Research outcomes will be targeted for industrial application. As such, translation of new scientific approaches into direct business application will be a key part of the role, allowing for improved assessment of Unilever's product portfolio across our business groups (Nutrition, Home Care, Beauty & Wellbeing and Personal Care) to help deliver our ambition to be the global leader in sustainable business. RESPONSIBILITIES Environmental sustainability science strategy development and implementation: ongoingevolution of current research strategy,partnerships, funding mechanisms and dissemination plans. Development of new scientific approaches: deliver new scientific methods relating to life cycle assessment and associated approaches (e.g. spatially and temporally resolved impact assessment, prospective and ex-ante LCA, absolute sustainability, data generation approaches), including writing reports and publications. Application of LCA software and computational approaches (such as Simapro, Gabi, Brightway; Python, R, MATLAB; GIS) to enable cutting-edge LCA approaches to be developed and applied in industry. External engagement with universities, research groups, trade associations and suppliers. ALL ABOUT YOU You'll need to be able to work effectively and with impact in cross-disciplinary teams and in multi-cultural environments and be flexible and willing to adapt within a fast-changing business environment. We would expect the successful candidate to: Have a relevant PhD, ideally with several years of industrial/consulting/post doc experience. Have science leadership experience including development of project proposals and collaborative partnerships as well as a proven track record in project management. Have experience in the development, application and evaluation of Life Cycle Impact Assessment or footprinting methodologies and potentially associated standards, protocols, databases or tools. Ability to communicate complex scientific information and rationales on environmental sustainability to individuals from other disciplines or from non-technical backgrounds as well as via publications. Ability to employ a strategic and growth mindset. Proven track record of leading / working as part of a team. Willingness to explore and learn new approaches and to support others in doing so. If you have the following skills, that's a bonus but not essential: Broader sustainability expertise in any of the following areas: bio-based systems, agriculture, ecosystem services / natural capital, green chemistry, circular economy, industrial ecology. Experience of employing approaches to assess variability and uncertainty in impact assessments. Experience of using Input/Output (I/O) analysis and related methods. Predictive modelling ideally with a focus on sustainable consumption and land system changes, e.g. understanding and experience of using Land Change models (LCM). LOCATION Colworth Park is a vibrant scientific ecosystem with around 800 employees (500 from Unilever R&D) based on site from over 30 nationalities, with 88 PhDs, 8 Professors, 50 apprentices. On site there are various facilities including a restaurant, a nursery and a gym. There are many social and recreational activities to take part in, such as going for a lunchtime walk or run in the beautiful surrounding countryside, the Colworth choir, and netball team to name just a few. London with all of its attractions is a short 40-minute train ride from Bedford. ABOUT SERS We want consumers to be confident that our products are safe for them and their families, and better for the environment. The scientists in Unilever's Safety, Environmental and Regulatory Science (SERS) group play a key role in ensuring that our products are safe and our business is environmentally sustainable. SERS's world-class reputation for safety and sustainability science plays a key role in Unilever achieving its purpose, by working across the business to build safety and environmental sustainability into everything we do; find out how at . ABOUT UNILEVER Unilever is one of the world's leading suppliers of Food, Home and Personal Care products with sales in over 190 countries and reaching 2 billion consumers a day. Unilever has more than 400 brands found in homes around the world, including Dove, Tresemme, Lynx, Lifebuoy, Shea Moisture, Persil, Domestos, Marmite, Graze and Pot Noodle. NOTES About Unilever Unilever is one of the world's leading suppliers of Food, Home and Personal Care products with sales in over 190 countries and reaching 2 billion consumers a day. Unilever has more than 400 brands found in homes around the world, including Dove, Tresemme, Lynx, Lifebuoy, Shea Moisture, Persil, Domestos, Ben & Jerry's, Magnum, Marmite, The Vegetarian Butcher, Graze and Pot Noodle. Faced with the challenge of climate change and the need for human development, we want to move towards a world where everyone can live well and within the natural limits of the planet. That's why our purpose is 'to make sustainable living commonplace' What We Offer Not only do we offer a competitive salary and pension scheme, we also offer an annual bonus, subsidised gym membership, a discounted staff shop and shares. You'll have the opportunity to work directly with our renowned and exciting brands in a flexible and hybrid working environment. Whilst the role is advertised on a full-time basis, we would be happy to discuss possible flexible working options and what this may look like for you. We are a key advocate of wellbeing and offer a variety of support for our people including hubs, programmes and development opportunities. We strive to achieve a family-friendly and inclusive workplace and to, above all, create possibilities for all. Diversity at Unilever is about inclusion, embracing differences, creating possibilities and growing together for better business performance. We embrace diversity in our workforce. This means giving full and fair consideration to all applicants and continuing development of all employees regardless of age, disability, gender reassignment, race, religion or belief, sex, sexual orientation, marriage and civil partnership, and pregnancy and maternity. We are also more than happy to provide reasonable adjustments during our application and interview process to enable you to be present your best self. To find out more, including about our Employee Resource Groups, please click here Equity, Diversity & Inclusion at Unilever Unilever . Recruitment Fraud Cyber criminals advertise fake job adverts with prestigious employers as a way of stealing information or even defrauding individuals out of money. In the most sophisticated cases, they will set up fake websites, which have a similar address to companies like Unilever. They even conduct fake telephone interviews and then offer candidates a role with the proviso they pay a fee for background checks or to cover work visa costs. These types of attacks are becoming more common as more people are looking for employment in the economic climate. How is Unilever tackling this? Many of Unilever's recruitment sites publish a warning to candidates about recruitment fraud. The Cyber Security team also proactively scan for signs of people setting up fake Unilever sites and act to close them down. What can I do? If you become aware of potential recruitment fraud, spot fake Unilever recruitment adverts or fake LinkedIn profiles, report them via Una Live Chat. Unilever does not accept responsibility or liability for any candidates who are financially impacted by recruitment fraud. Your vigilance is key!
The Amazon Alexa AI team in India is seeking a talented, self-driven Applied Scientist to work on prototyping, optimizing, and deploying ML algorithms within the realm of Generative AI. Key Responsibilities Research, experiment and build Proof Of Concepts advancing the state of the art in AI & ML for GenAI. Collaborate with cross-functional teams to architect and execute technically rigorous AI projects. Thrive in dynamic environments, adapting quickly to evolving technical requirements and deadlines. Engage in effective technical communication (written & spoken) with coordination across teams. Conduct thorough documentation of algorithms, methodologies, and findings for transparency and reproducibility. Publish research papers in internal and external venues of repute. Support on-call activities for critical issues. Basic Qualifications Master's or PhD in computer science, statistics or a related field. 5+ years experience in deep learning, machine learning, and data science. Proficiency in coding and software development, with a strong focus on machine learning frameworks. Experience in Python, or another language; command line usage; familiarity with Linux and AWS ecosystems. Understanding of relevant statistical measures such as confidence intervals, significance of error measurements, development and evaluation data sets, etc. Excellent communication skills (written & spoken) and ability to collaborate effectively in a distributed, cross-functional team setting. Papers published in AI/ML venues of repute. Preferred Qualifications Track record of diving into data to discover hidden patterns and conducting error/deviation analysis. Ability to develop experimental and analytic plans for data modeling processes, use of strong baselines, ability to accurately determine cause and effect relations. The motivation to achieve results in a fast-paced environment. Exceptional level of organization and strong attention to detail. Comfortable working in a fast paced, highly collaborative, dynamic work environment. About the Team The team works on building Responsible AI alignment techniques for the Large Language Model (LLM) that drives Alexa+. We work on recent advances in LLM science including automated prompt optimisation, supervised fine tuning, reinforcement learning, model distillation, retrieval augmented generation, model & prompt interpretability and LLM driven data generation. The techniques are used to tune a foundational model to align with Alexa's policies on Responsible AI across dimensions of Appropriateness, Safety, Security, Privacy and Fairness. We focus on building cross-lingual methods to support 100s of millions of Alexa customers across the world speaking 15+ languages. A scientist on the team works on the following - a) running experiments to evaluate promising ideas to achieve a customer experience goal; b) Identify a research theme and follow recent advances in the space (papers/articles); c) collaborate with other scientists (within and outside team) to identify a science direction to solve a problem; d) publish papers in peer-reviewed conferences & journals of repute; e) Collaborate with faculty members in Indian academia (e.g. IIT-B). The team's work was part of the Alexa+ launch announcement:
Jun 19, 2025
Full time
The Amazon Alexa AI team in India is seeking a talented, self-driven Applied Scientist to work on prototyping, optimizing, and deploying ML algorithms within the realm of Generative AI. Key Responsibilities Research, experiment and build Proof Of Concepts advancing the state of the art in AI & ML for GenAI. Collaborate with cross-functional teams to architect and execute technically rigorous AI projects. Thrive in dynamic environments, adapting quickly to evolving technical requirements and deadlines. Engage in effective technical communication (written & spoken) with coordination across teams. Conduct thorough documentation of algorithms, methodologies, and findings for transparency and reproducibility. Publish research papers in internal and external venues of repute. Support on-call activities for critical issues. Basic Qualifications Master's or PhD in computer science, statistics or a related field. 5+ years experience in deep learning, machine learning, and data science. Proficiency in coding and software development, with a strong focus on machine learning frameworks. Experience in Python, or another language; command line usage; familiarity with Linux and AWS ecosystems. Understanding of relevant statistical measures such as confidence intervals, significance of error measurements, development and evaluation data sets, etc. Excellent communication skills (written & spoken) and ability to collaborate effectively in a distributed, cross-functional team setting. Papers published in AI/ML venues of repute. Preferred Qualifications Track record of diving into data to discover hidden patterns and conducting error/deviation analysis. Ability to develop experimental and analytic plans for data modeling processes, use of strong baselines, ability to accurately determine cause and effect relations. The motivation to achieve results in a fast-paced environment. Exceptional level of organization and strong attention to detail. Comfortable working in a fast paced, highly collaborative, dynamic work environment. About the Team The team works on building Responsible AI alignment techniques for the Large Language Model (LLM) that drives Alexa+. We work on recent advances in LLM science including automated prompt optimisation, supervised fine tuning, reinforcement learning, model distillation, retrieval augmented generation, model & prompt interpretability and LLM driven data generation. The techniques are used to tune a foundational model to align with Alexa's policies on Responsible AI across dimensions of Appropriateness, Safety, Security, Privacy and Fairness. We focus on building cross-lingual methods to support 100s of millions of Alexa customers across the world speaking 15+ languages. A scientist on the team works on the following - a) running experiments to evaluate promising ideas to achieve a customer experience goal; b) Identify a research theme and follow recent advances in the space (papers/articles); c) collaborate with other scientists (within and outside team) to identify a science direction to solve a problem; d) publish papers in peer-reviewed conferences & journals of repute; e) Collaborate with faculty members in Indian academia (e.g. IIT-B). The team's work was part of the Alexa+ launch announcement:
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Jun 19, 2025
Full time
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Jun 19, 2025
Full time
Location: London Length: 12 months (with potential for extension) PAYE only Overall purpose of the role Be at the Heart of Innovation! Join Barclays and play a pivotal role in revolutionizing how we understand and engage with our colleagues. We're looking for a dynamic Agile Delivery Lead to drive the development and delivery of cutting-edge applications that measure and enhance colleague sentiment and organisational effectiveness. Dive into an environment where your leadership will shape the future of our internal experiences. You'll lead the delivery of multiple products, from initial pilots to full-scale rollouts, directly impacting how Barclays leverages data and insights to create a better workplace. Key Accountabilities: Day-to-day management of product delivery, ensuring projects stay on track Collaborating with cross-functional teams to gather requirements and ensure product alignment Driving customer-centric development and incorporating feedback into iterations Lead and manage the end-to-end delivery of multiple colleague measurement products (apps, surveys, data frameworks) Facilitate Agile ceremonies including sprint planning, daily stand-ups, and retrospectives Work closely with a team of behavioural scientists, providing structure and direction to product development Create executive summaries for Senior MDs and present updates using compelling PowerPoint presentations Implement and coach Agile methodologies within the team, driving a shift towards Agile mindsets Identify and mitigate project risks and challenges Required Skills and Experience: Extensive experience in product development and delivery Strong understanding and practical application of Agile methodologies Proven ability to lead sprint planning, retrospectives, and daily stand-ups Experience with Jira Excellent communication and presentation skills Customer-centric approach with a focus on understanding and addressing user needs Desirable Skills: Agile certification Previous experience in establishing or working within a Product Office Experience with Agile coaching and training Understanding of behavioural science principles (not essential) About Barclays Barclays is a British universal bank. It is diversified by business, by different types of customers and clients, and by geography. Barclays businesses include consumer banking and payments operations around the world, as well as a top-tier, full service, global corporate and investment bank, all of which are supported by its service company which provides technology, operations and functional services across the Group. Values Everything Barclays does is shaped by its five values of Respect, Integrity, Service, Excellence and Stewardship. The Barclays values inform the foundations of its relationships with customers and clients, but they also shape how Barclays measure and reward the performance of colleagues. Simply put, success is not just about what you achieve, but about how you achieve it. Diversity Barclays aims to foster a culture where individuals of all backgrounds feel confident in bringing their whole selves to work, feel included and their talents are nurtured, empowering them to contribute fully to Barclays vision and goals. Hybrid working At Barclays, we offer a hybrid working experience that blends the positives of working alongside colleagues at our onsite locations, together with working from home. We have a structured approach where colleagues work at an onsite location on fixed, 'anchor', days of the week, for a minimum of two days a week or more, as set by the business area (or nearest equivalent if working part-time hours). Please discuss the working pattern requirements for the role you are applying for with the hiring manager. Please note that as we continue to embed our hybrid working environment, we remain in a test and learn phase, which means that working arrangements may be subject to change on reasonable notice to ensure we meet the needs of our business. Your Benefits As a contract employee of Randstad Sourceright, you'll receive a wide range of financial and personal benefits. There's enrolment in a pension plan (after 12 weeks on assignment) and holiday pay. You'll also get 24/7 access to an Employee Assistance Programme, designed to help you deal with any problems that could be affecting your home or work life. Plus, there's discounts at heaps of high street shops, restaurants and entertainment - from Asda to Zizzi Italian restaurants.
Our client is a growing Life Science company based in Oxfordshire, who are currently looking to build their R&D team with the addition of an Senior Analytical Scientist. This opportunity will be a full-time role and will support the company in developing ground-breaking approaches to vaccine delivery. The role: As an Analytical Scientist you will support with on-going R&D projects, proving analytical supporting pharmaceutical development of mRNA-loaded particles. Core responsibilities will include: Develop and apply analytical characterisation methods Support with analytical method development and validation for HPLC, DLS, Gel Electrophoresis, Western Blot. Interpretation and presentation of Analytical data to be utilised to support R&D projects Update standard operating protocols (SOP's) as required Perform additional QC testing and equipment calibration Suitable applicants: Our client is looking for candidates who are seeking a collaborative working environment and is able to work cross-functionally with internal teams, to achieve project success. Suitable applicants will have: Prior experience in the analysis and characterisation of lipids, biopolymers and/or complex molecular systems Experience with HPLC and LCMS, UV-Vis, FTIR, etc. Experience working within a GMP or ISO accredited laboratory environment Prior experience with nanoparticle emulsions, micelles, lipids or nucleotides would be advantageous Excellent communication skills and experience working cross-functionally In return, my client offers the opportunity to join a developing, small company with exposure to exciting research. A competitive salary will be offered based on experience. I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . Name Email address Telephone Message Upload C.V. Your file must be in one of the following formats: pdf , doc , docx , rtf , txt and no larger than 2MB . Recaptcha requires verification. I'm not a robot reCAPTCHA Privacy - Terms
Jun 19, 2025
Full time
Our client is a growing Life Science company based in Oxfordshire, who are currently looking to build their R&D team with the addition of an Senior Analytical Scientist. This opportunity will be a full-time role and will support the company in developing ground-breaking approaches to vaccine delivery. The role: As an Analytical Scientist you will support with on-going R&D projects, proving analytical supporting pharmaceutical development of mRNA-loaded particles. Core responsibilities will include: Develop and apply analytical characterisation methods Support with analytical method development and validation for HPLC, DLS, Gel Electrophoresis, Western Blot. Interpretation and presentation of Analytical data to be utilised to support R&D projects Update standard operating protocols (SOP's) as required Perform additional QC testing and equipment calibration Suitable applicants: Our client is looking for candidates who are seeking a collaborative working environment and is able to work cross-functionally with internal teams, to achieve project success. Suitable applicants will have: Prior experience in the analysis and characterisation of lipids, biopolymers and/or complex molecular systems Experience with HPLC and LCMS, UV-Vis, FTIR, etc. Experience working within a GMP or ISO accredited laboratory environment Prior experience with nanoparticle emulsions, micelles, lipids or nucleotides would be advantageous Excellent communication skills and experience working cross-functionally In return, my client offers the opportunity to join a developing, small company with exposure to exciting research. A competitive salary will be offered based on experience. I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . Name Email address Telephone Message Upload C.V. Your file must be in one of the following formats: pdf , doc , docx , rtf , txt and no larger than 2MB . Recaptcha requires verification. I'm not a robot reCAPTCHA Privacy - Terms
Salary: £26,000 - £35,000 depending on experience and interview performance Work Hours: 40 hrs a week, Monday to Friday (09:00 - 17:30) Our client is an innovative biotechnology company based outside of the centre of Cambridge. They have built a platform to synthesise DNA and RNA which provides exciting possibilities for ensuring cheaper, faster and more accurate DNA / gene constructs than traditional plasmid-based methods. They work with external partners to develop gene therapy projects and have some internal projects too. Additionally they have AAV and Lipid-nanoparticle technology platforms in-house. In a key phase of their growth, our client is looking to bring a DNA Scientist to their process development team on a full-time and permanent basis. The Opportunity This is an opportunity suitable for a BSc / MSc holder in a Biological discipline, alongside additional laboratory experience (either in industry or academia). As a DNA Scientist, you will be responsible for: Supporting the process development and tech transfer functions with synthetic DNA projects. Validating and optimising various molecular biology (and potentially biochemistry) experiments to enable efficient product development and transfer to manufacturing. This may include: DNA handling, PCR, gel electrophoresis, capillary electrophoresis, TFF, AKTA purification, DNA quantification (nanodrop / Qubit) etc. Optimise and improve processes within the DNA team, working alongside other teams including R&D and manufacturing. Record scientific data in accordance with company policy and presenting data to internal teams. Attending company / team meetings. Skills and Experience Needed The ideal candidate will have the following: BSc / MSc in Biology / Biochemistry and an additional 1+ year of laboratory experience gained in academia or industry (essential, equivalent experience okay) Must have proven experience in designing experiments and planning experiment schedules (essential) Prior experience in DNA and molecular biology, with experience in some of the following techniques: micropipetting, gel electrophoresis, DNA quantification (Spectrophotometry / Qubit / nanodrop), PCR, cloning, primer design (essential) Experience in Tangential flow filtration (TFF), capillary electrophoresis or AKTA systems would be an advantage (desired) Excellent attention to detail. (essential) Ability to work effectively in a team and individually (essential) Experience working in an industrial biological laboratory (desired) The Package As an up-and-coming Cambridge Biotech, our client is able to offer a competitive salary, progression options and benefits package including private pension. To Apply If you would like to apply to this opportunity, please send a copy of your CV to Charlie Cox at - alternatively, please call Charlie on . I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . Name Email address Telephone Message Upload C.V. Your file must be in one of the following formats: pdf , doc , docx , rtf , txt and no larger than 2MB . Recaptcha requires verification. I'm not a robot reCAPTCHA Privacy - Terms
Jun 19, 2025
Full time
Salary: £26,000 - £35,000 depending on experience and interview performance Work Hours: 40 hrs a week, Monday to Friday (09:00 - 17:30) Our client is an innovative biotechnology company based outside of the centre of Cambridge. They have built a platform to synthesise DNA and RNA which provides exciting possibilities for ensuring cheaper, faster and more accurate DNA / gene constructs than traditional plasmid-based methods. They work with external partners to develop gene therapy projects and have some internal projects too. Additionally they have AAV and Lipid-nanoparticle technology platforms in-house. In a key phase of their growth, our client is looking to bring a DNA Scientist to their process development team on a full-time and permanent basis. The Opportunity This is an opportunity suitable for a BSc / MSc holder in a Biological discipline, alongside additional laboratory experience (either in industry or academia). As a DNA Scientist, you will be responsible for: Supporting the process development and tech transfer functions with synthetic DNA projects. Validating and optimising various molecular biology (and potentially biochemistry) experiments to enable efficient product development and transfer to manufacturing. This may include: DNA handling, PCR, gel electrophoresis, capillary electrophoresis, TFF, AKTA purification, DNA quantification (nanodrop / Qubit) etc. Optimise and improve processes within the DNA team, working alongside other teams including R&D and manufacturing. Record scientific data in accordance with company policy and presenting data to internal teams. Attending company / team meetings. Skills and Experience Needed The ideal candidate will have the following: BSc / MSc in Biology / Biochemistry and an additional 1+ year of laboratory experience gained in academia or industry (essential, equivalent experience okay) Must have proven experience in designing experiments and planning experiment schedules (essential) Prior experience in DNA and molecular biology, with experience in some of the following techniques: micropipetting, gel electrophoresis, DNA quantification (Spectrophotometry / Qubit / nanodrop), PCR, cloning, primer design (essential) Experience in Tangential flow filtration (TFF), capillary electrophoresis or AKTA systems would be an advantage (desired) Excellent attention to detail. (essential) Ability to work effectively in a team and individually (essential) Experience working in an industrial biological laboratory (desired) The Package As an up-and-coming Cambridge Biotech, our client is able to offer a competitive salary, progression options and benefits package including private pension. To Apply If you would like to apply to this opportunity, please send a copy of your CV to Charlie Cox at - alternatively, please call Charlie on . I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . I'm interested in this job Please use the form provided to get in touch with us and we will respond as soon as possible. Compulsory fields are in bold . Name Email address Telephone Message Upload C.V. Your file must be in one of the following formats: pdf , doc , docx , rtf , txt and no larger than 2MB . Recaptcha requires verification. I'm not a robot reCAPTCHA Privacy - Terms
