About Anthropic Anthropic's mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role Anthropic's mission is to ensure the world safely makes the transition through transformative AI. As part of this mission, we have advocated that democracies should continue to lead the development and deployment of powerful and trusted frontier AI, particularly for national security. We work closely with relevant national security communities to deliver this ambition. We are looking for a National Security Lead to guide our strategic engagements with European national security and intelligence communities. Working closely with the national security team based in the US and the EMEA policy team, this senior role will help to shape Anthropic's approach to national security policy and partnerships in Europe during a critical period in AI development and governance. You will be the day to day point of contact with European national security partners, both ensuring that Anthropic's leadership understands their priorities, and translating technology and policy developments within Anthropic for national security partners. You will also work closely with our EMEA public sector sales team to support public sector deployment of Claude in high-leverage use cases that strengthen national security, enhance government efficiency, and accelerate allied competitiveness. This role is based in London. In this role you will: Lead policy engagement with European national security partners on issues related to government use and national security implications of frontier models Engage key NatSec policy stakeholders (e.g., via briefings, consultations, demos, roundtables), in coordination with the wider national security and EMEA policy teams Partner with the EMEA public sector sales team to support commercial efforts involving government agency deployments Support and promote public-private research collaborations Build a coalition of government agencies, nonprofits, safety institutes, and academics to in Europe to share knowledge around national security issues Collaborate with technical teams to translate Anthropic threat model research into concrete policy proposals, stakeholder education, and thought leadership opportunities You may be a good fit if you: Have 10+ years of experience working in national security agencies, or a combination of government and related private sector experience Are high-agency, able to develop and execute strategy independently, taking account of dependencies with other cross functional teams within Anthropic (including but not limited to policy, go to market, trust and safety, legal, product, research, comms, and marketing). Possess strong written and verbal communication skills, particularly when briefing policymakers and government officials Have demonstrated interest and experience in a complicated technical subject (ideally, AI, but other examples could be quantum computing, cryptography, fusion power, etc.) Have had some legal training in or exposure to contract negotiations Are willing/able to participate in a process to obtain/retain Developed Vetting clearance in the UK This role is based in London. This job will also require travel in Europe and to the United States. The expected base compensation for this position is below. Our total compensation package for full time employees includes equity, benefits, and may include incentive compensation. Annual Salary: £185,000 - £185,000 GBP Logistics Education requirements: We require at least a Bachelor's degree in a related field or equivalent experience. Location based hybrid policy: Currently, we expect all staff to be in one of our offices at least 25% of the time. However, some roles may require more time in our offices. Visa sponsorship: We do sponsor visas! However, we aren't able to successfully sponsor visas for every role and every candidate. But if we make you an offer, we will make every reasonable effort to get you a visa, and we retain an immigration lawyer to help with this. We encourage you to apply even if you do not believe you meet every single qualification. Not all strong candidates will meet every single qualification as listed. Research shows that people who identify as being from underrepresented groups are more prone to experiencing imposter syndrome and doubting the strength of their candidacy, so we urge you not to exclude yourself prematurely and to submit an application if you're interested in this work. We think AI systems like the ones we're building have enormous social and ethical implications. We think this makes representation even more important, and we strive to include a range of diverse perspectives on our team. How we're different We believe that the highest impact AI research will be big science. At Anthropic we work as a single cohesive team on just a few large scale research efforts. And we value impact - advancing our long term goals of steerable, trustworthy AI - rather than work on smaller and more specific puzzles. We view AI research as an empirical science, which has as much in common with physics and biology as with traditional efforts in computer science. We're an extremely collaborative group, and we host frequent research discussions to ensure that we are pursuing the highest impact work at any given time. As such, we greatly value communication skills. The easiest way to understand our research directions is to read our recent research. This research continues many of the directions our team worked on prior to Anthropic, including: GPT 3, Circuit Based Interpretability, Multimodal Neurons, Scaling Laws, AI & Compute, Concrete Problems in AI Safety, and Learning from Human Preferences. Come work with us! Anthropic is a public benefit corporation headquartered in San Francisco. We offer competitive compensation and benefits, optional equity donation matching, generous vacation and parental leave, flexible working hours, and a lovely office space in which to collaborate with colleagues. Guidance on Candidates' AI Usage: Learn about our policy for using AI in our application process
Dec 08, 2025
Full time
About Anthropic Anthropic's mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role Anthropic's mission is to ensure the world safely makes the transition through transformative AI. As part of this mission, we have advocated that democracies should continue to lead the development and deployment of powerful and trusted frontier AI, particularly for national security. We work closely with relevant national security communities to deliver this ambition. We are looking for a National Security Lead to guide our strategic engagements with European national security and intelligence communities. Working closely with the national security team based in the US and the EMEA policy team, this senior role will help to shape Anthropic's approach to national security policy and partnerships in Europe during a critical period in AI development and governance. You will be the day to day point of contact with European national security partners, both ensuring that Anthropic's leadership understands their priorities, and translating technology and policy developments within Anthropic for national security partners. You will also work closely with our EMEA public sector sales team to support public sector deployment of Claude in high-leverage use cases that strengthen national security, enhance government efficiency, and accelerate allied competitiveness. This role is based in London. In this role you will: Lead policy engagement with European national security partners on issues related to government use and national security implications of frontier models Engage key NatSec policy stakeholders (e.g., via briefings, consultations, demos, roundtables), in coordination with the wider national security and EMEA policy teams Partner with the EMEA public sector sales team to support commercial efforts involving government agency deployments Support and promote public-private research collaborations Build a coalition of government agencies, nonprofits, safety institutes, and academics to in Europe to share knowledge around national security issues Collaborate with technical teams to translate Anthropic threat model research into concrete policy proposals, stakeholder education, and thought leadership opportunities You may be a good fit if you: Have 10+ years of experience working in national security agencies, or a combination of government and related private sector experience Are high-agency, able to develop and execute strategy independently, taking account of dependencies with other cross functional teams within Anthropic (including but not limited to policy, go to market, trust and safety, legal, product, research, comms, and marketing). Possess strong written and verbal communication skills, particularly when briefing policymakers and government officials Have demonstrated interest and experience in a complicated technical subject (ideally, AI, but other examples could be quantum computing, cryptography, fusion power, etc.) Have had some legal training in or exposure to contract negotiations Are willing/able to participate in a process to obtain/retain Developed Vetting clearance in the UK This role is based in London. This job will also require travel in Europe and to the United States. The expected base compensation for this position is below. Our total compensation package for full time employees includes equity, benefits, and may include incentive compensation. Annual Salary: £185,000 - £185,000 GBP Logistics Education requirements: We require at least a Bachelor's degree in a related field or equivalent experience. Location based hybrid policy: Currently, we expect all staff to be in one of our offices at least 25% of the time. However, some roles may require more time in our offices. Visa sponsorship: We do sponsor visas! However, we aren't able to successfully sponsor visas for every role and every candidate. But if we make you an offer, we will make every reasonable effort to get you a visa, and we retain an immigration lawyer to help with this. We encourage you to apply even if you do not believe you meet every single qualification. Not all strong candidates will meet every single qualification as listed. Research shows that people who identify as being from underrepresented groups are more prone to experiencing imposter syndrome and doubting the strength of their candidacy, so we urge you not to exclude yourself prematurely and to submit an application if you're interested in this work. We think AI systems like the ones we're building have enormous social and ethical implications. We think this makes representation even more important, and we strive to include a range of diverse perspectives on our team. How we're different We believe that the highest impact AI research will be big science. At Anthropic we work as a single cohesive team on just a few large scale research efforts. And we value impact - advancing our long term goals of steerable, trustworthy AI - rather than work on smaller and more specific puzzles. We view AI research as an empirical science, which has as much in common with physics and biology as with traditional efforts in computer science. We're an extremely collaborative group, and we host frequent research discussions to ensure that we are pursuing the highest impact work at any given time. As such, we greatly value communication skills. The easiest way to understand our research directions is to read our recent research. This research continues many of the directions our team worked on prior to Anthropic, including: GPT 3, Circuit Based Interpretability, Multimodal Neurons, Scaling Laws, AI & Compute, Concrete Problems in AI Safety, and Learning from Human Preferences. Come work with us! Anthropic is a public benefit corporation headquartered in San Francisco. We offer competitive compensation and benefits, optional equity donation matching, generous vacation and parental leave, flexible working hours, and a lovely office space in which to collaborate with colleagues. Guidance on Candidates' AI Usage: Learn about our policy for using AI in our application process
Teacher of Biology (Science) In the heart of Wandsworth an 'Outstanding' Secondary School are on the hunt for a Teacher of Biology (Science) for a Jan 2026 start. This is a permanent, and full-time contract. The Head Teacher is looking for an ambitious Teacher of Biology (Science) who is keen to add value to an expanding Science Department. The school is renowned for their supportive SLT, and impressive Progress 8 results across all subjects. The school are well invested into the Education sector setting new teaching practices, as well as training their own and new staff. It's an exciting time at the school! Experienced Science Teachers can take on a TLR such as KS3 Coordinator, Pastoral Responsibility and more. Early Careers Teachers (ECTs) will be enrolled onto the school's very own bespoke ECT induction, as well as work alongside a range of young & experienced Science Teachers. Does this sound like the Teacher of Biology (Science) for you? If so, please read on below to find out further information! JOB DESCRIPTION Teacher of Biology (Science) Inspiring and motivating the younger generation Working alongside a team of fantastic Science Teachers TLR Opportunities: KS3 Coordinator and Pastoral Responsibilities ECTs welcome: 1:1 Mentor, bespoke NQT induction, In & out of house training and more Jan 26 Start - Full Time & Permanent MPS1-UPS3 - £38,766 - £60,092 + TLR (Size depending on experience) Located in the Borough of Wandsworth PERSON SPECIFICATION Must have UK QTS or be in the process of gaining Strong academics across the board - Degree, A Levels and GCSEs Must be meeting the 8 Teaching Standards to a 'Good or Outstanding' level You must be able to work as part of a large team of Science Teachers Must be willing to listen to feedback SCHOOL DETAILS Graded 'Outstanding' in latest Ofsted report Impressive Progress 8 results Modern & creative facilities throughout Impeccable behaviour throughout the School Plenty of additional support in class from graduate Teaching Assistants Good Tube Links - Wandsworth Carpark onsite If you are interested in this Teacher of Biology (Science) opportunity, interviews & lesson observations can be arranged immediately! Apply for this Teacher of Biology (Science) opportunity by sending your CV to Charlie at EdEx. You will be contacted by your personal consultant (if shortlisted)! Teacher of Biology (Science) INDT
Dec 05, 2025
Full time
Teacher of Biology (Science) In the heart of Wandsworth an 'Outstanding' Secondary School are on the hunt for a Teacher of Biology (Science) for a Jan 2026 start. This is a permanent, and full-time contract. The Head Teacher is looking for an ambitious Teacher of Biology (Science) who is keen to add value to an expanding Science Department. The school is renowned for their supportive SLT, and impressive Progress 8 results across all subjects. The school are well invested into the Education sector setting new teaching practices, as well as training their own and new staff. It's an exciting time at the school! Experienced Science Teachers can take on a TLR such as KS3 Coordinator, Pastoral Responsibility and more. Early Careers Teachers (ECTs) will be enrolled onto the school's very own bespoke ECT induction, as well as work alongside a range of young & experienced Science Teachers. Does this sound like the Teacher of Biology (Science) for you? If so, please read on below to find out further information! JOB DESCRIPTION Teacher of Biology (Science) Inspiring and motivating the younger generation Working alongside a team of fantastic Science Teachers TLR Opportunities: KS3 Coordinator and Pastoral Responsibilities ECTs welcome: 1:1 Mentor, bespoke NQT induction, In & out of house training and more Jan 26 Start - Full Time & Permanent MPS1-UPS3 - £38,766 - £60,092 + TLR (Size depending on experience) Located in the Borough of Wandsworth PERSON SPECIFICATION Must have UK QTS or be in the process of gaining Strong academics across the board - Degree, A Levels and GCSEs Must be meeting the 8 Teaching Standards to a 'Good or Outstanding' level You must be able to work as part of a large team of Science Teachers Must be willing to listen to feedback SCHOOL DETAILS Graded 'Outstanding' in latest Ofsted report Impressive Progress 8 results Modern & creative facilities throughout Impeccable behaviour throughout the School Plenty of additional support in class from graduate Teaching Assistants Good Tube Links - Wandsworth Carpark onsite If you are interested in this Teacher of Biology (Science) opportunity, interviews & lesson observations can be arranged immediately! Apply for this Teacher of Biology (Science) opportunity by sending your CV to Charlie at EdEx. You will be contacted by your personal consultant (if shortlisted)! Teacher of Biology (Science) INDT
Site Name: UK - County Durham - Barnard Castle Posted Date: Dec 2 2025 GSK Barnard Castle is a key secondary manufacturing site and has invested heavily in industry 4.0 state of the art, bespoke equipment to support sustained new product introductions and volume increases, and as a key supplier of some of GSK's blockbuster products, the site contributes revenues of $2Bn annually. We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme. We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work. Discover more about our company wide benefits and life at GSK on our webpage Life at GSK GSK The Sterility Assurance Facility Manager leads sterility assurance projects and has overall oversight of facilities within their areas of responsibility, ensuring compliance with regulatory requirements and industry standards. This role drives contamination control strategies (CCS), ensures the implementation of sterility assurance measures across site facilities, and collaborates with operations to ensure the consistent application of sterility assurance requirements. In this role you will Lead sterility assurance projects to ensure contamination control strategies (CCS) are effectively implemented and aligned with site objectives and regulatory requirements. Provide overall oversight of facility operations, ensuring compliance with sterility assurance standards and contamination control measures. Drive the implementation of sterility assurance programmes across facilities, collaborating with cross-functional teams site and above site teams to ensure consistency and effectiveness. Ensure facilities are maintained and operated in alignment with industry best practices, regulatory requirements, and contamination prevention principles. Collaborate with operations and quality teams to ensure contamination control measures are integrated effectively into manufacturing processes. Monitor performance metrics related to facility operations and contamination control, identifying areas for improvement and implementing corrective actions as needed. Act as the primary point of contact for sterility assurance within facilities, representing the team during audits, inspections, and internal reviews. Contribute to the harmonisation and continuous improvement of sterility assurance practices across the organisation, sharing knowledge and best practices. Develop and deliver training programmes, ensuring staff understand and consistently apply sterility assurance and contamination control measures. Support the strategic planning and execution of facility upgrades or projects to optimise contamination control systems and ensure regulatory compliance. Why you? Basic Qualifications & Skills: Bachelor's degree in Chemistry, Biochemistry, Microbiology, or a related field Significant experience in sterility assurance within the pharmaceutical, biotechnology, or related industry Strong knowledge of regulatory requirements around sterility assurance and sterile manufacturing (e.g., FDA, MHRA, EMA) and industry standards (e.g., cGMP, ISO). Excellent problem-solving skills and attention to detail. Strong leadership and project management abilities. Effective communication and interpersonal skills. Preferred Qualifications & Skills: An advanced degree in Chemistry, Biochemistry, Microbiology, or a related field provides advanced knowledge of the scientific principles and methodologies that are crucial for ensuring product quality in the pharmaceutical industry. Closing Date: Closing Date: 16th December 2025 (COB) Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or . The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.
Dec 05, 2025
Full time
Site Name: UK - County Durham - Barnard Castle Posted Date: Dec 2 2025 GSK Barnard Castle is a key secondary manufacturing site and has invested heavily in industry 4.0 state of the art, bespoke equipment to support sustained new product introductions and volume increases, and as a key supplier of some of GSK's blockbuster products, the site contributes revenues of $2Bn annually. We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme. We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work. Discover more about our company wide benefits and life at GSK on our webpage Life at GSK GSK The Sterility Assurance Facility Manager leads sterility assurance projects and has overall oversight of facilities within their areas of responsibility, ensuring compliance with regulatory requirements and industry standards. This role drives contamination control strategies (CCS), ensures the implementation of sterility assurance measures across site facilities, and collaborates with operations to ensure the consistent application of sterility assurance requirements. In this role you will Lead sterility assurance projects to ensure contamination control strategies (CCS) are effectively implemented and aligned with site objectives and regulatory requirements. Provide overall oversight of facility operations, ensuring compliance with sterility assurance standards and contamination control measures. Drive the implementation of sterility assurance programmes across facilities, collaborating with cross-functional teams site and above site teams to ensure consistency and effectiveness. Ensure facilities are maintained and operated in alignment with industry best practices, regulatory requirements, and contamination prevention principles. Collaborate with operations and quality teams to ensure contamination control measures are integrated effectively into manufacturing processes. Monitor performance metrics related to facility operations and contamination control, identifying areas for improvement and implementing corrective actions as needed. Act as the primary point of contact for sterility assurance within facilities, representing the team during audits, inspections, and internal reviews. Contribute to the harmonisation and continuous improvement of sterility assurance practices across the organisation, sharing knowledge and best practices. Develop and deliver training programmes, ensuring staff understand and consistently apply sterility assurance and contamination control measures. Support the strategic planning and execution of facility upgrades or projects to optimise contamination control systems and ensure regulatory compliance. Why you? Basic Qualifications & Skills: Bachelor's degree in Chemistry, Biochemistry, Microbiology, or a related field Significant experience in sterility assurance within the pharmaceutical, biotechnology, or related industry Strong knowledge of regulatory requirements around sterility assurance and sterile manufacturing (e.g., FDA, MHRA, EMA) and industry standards (e.g., cGMP, ISO). Excellent problem-solving skills and attention to detail. Strong leadership and project management abilities. Effective communication and interpersonal skills. Preferred Qualifications & Skills: An advanced degree in Chemistry, Biochemistry, Microbiology, or a related field provides advanced knowledge of the scientific principles and methodologies that are crucial for ensuring product quality in the pharmaceutical industry. Closing Date: Closing Date: 16th December 2025 (COB) Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or . The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Job Role: We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team. Key Responsibilities: Utilize modern molecular modelling methods to support different stages of R&D programs. Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates. Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables. Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours. Set the vision and strategy for computational chemistry. Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry. Manage CRO compchem activities, providing expertise and guidance. Present plans and results internally, including at board level, and externally at conferences. Contribute to the writing of patent applications, scientific publications, and internal reports. Develop and mentor less experienced staff. Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies. Undertake ongoing professional development by attending relevant training and conferences. Requirements & Qualifications: MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting. Expert knowledge in CADD software packages and modern molecular modelling techniques. Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies. Passion for drug discovery with a deep entrepreneurial and problem-solving attitude. Mastery of all the theoretical and practical principles of medicinal chemistry and drug design. Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process. In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems. Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame. Demonstrated track record of scientific publications. Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Nov 17, 2025
Full time
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Job Role: We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team. Key Responsibilities: Utilize modern molecular modelling methods to support different stages of R&D programs. Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates. Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables. Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours. Set the vision and strategy for computational chemistry. Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry. Manage CRO compchem activities, providing expertise and guidance. Present plans and results internally, including at board level, and externally at conferences. Contribute to the writing of patent applications, scientific publications, and internal reports. Develop and mentor less experienced staff. Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies. Undertake ongoing professional development by attending relevant training and conferences. Requirements & Qualifications: MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting. Expert knowledge in CADD software packages and modern molecular modelling techniques. Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies. Passion for drug discovery with a deep entrepreneurial and problem-solving attitude. Mastery of all the theoretical and practical principles of medicinal chemistry and drug design. Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process. In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems. Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame. Demonstrated track record of scientific publications. Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
