90 jobs found

Science Technician (Chemisty) - Temporary Post 13 Aug The Board of Governors of the College invite applications for the above position(s). St Malachy's College is the oldest Catholic Boys' Grammar School in the Diocese of Down and Connor. The College is renowned for its outstanding pastoral care, excellent academic results and extra-curricular provision and performance. To provide organisational support to Chemistry and Junior Science teaching staff in the implementation of the College's/Department's educational programme. Essential Criteria: 5 GCSE's (Grade C or better) or equivalent qualification including Chemistry, English Language and Maths. Desirable Criteria: A Level Chemistry, successful completion of training for science technicians, laboratory work experience and/or knowledge of IT. Working hours & weeks: The post is term-time, with 195 working days (185 term-time days, 10 staff days). Working hours, Monday to Friday: 8.30am to 4.30pm. Deadline for receipt of Applications is Monday 24th August 2026 at 3:30pm

Job Title: Senior Scientist - Diagnostic Deployment Location: Cambridge, UK Introduction to role: Precision Diagnostics Development (PDD) within AstraZeneca focuses on matching medicines to those patients who will benefit most and delivering companion or complementary diagnostic assays aligned to drug development to enable personalised healthcare across our clinical portfolio. We are seeking a Senior Scientist to join our Accredited Diagnostic Development Laboratory (ADDL) at the Cambridge Biomedical Campus, supporting the development, optimisation, validation, and operational delivery of tissue-based diagnostic assays for AstraZeneca's clinical portfolio. This role is suited to an experienced laboratory scientist with a strong histology and immunohistochemistry (IHC) background, knowledge of digital and computational pathology, and a track record of delivering high-quality, reproducible testing within a regulated laboratory environment. You will play a hands-on role in the delivery of tissue-based and digital diagnostics that support clinical trial testing and assay deployment, combining technical excellence with the scientific rigour required to operate within accredited quality frameworks. In this role, you will also contribute to the integration of key systems across our end-to-end workflow, including LIMS, and collaborate across the broader process to identify opportunities for optimisation, efficiency, and streamlining. Accountabilities: Histology and IHC Delivery: Lead development, optimisation, validation, and operational delivery of tissue-based assays, setting the technical standard for consistency, turnaround time, and reproducibility that underpins clinical decision-making. Assay Validation: Design and execute analytical validation plans aligned with study needs and regulatory expectations, moving assays efficiently from development into prospective clinical testing. Digital and Computational Pathology: Apply whole-slide imaging and image analysis to strengthen assay scoring and interpretation; evaluate emerging digital capabilities to expand our diagnostic toolkit. Quality and Compliance: Embed CAP/CLIA, ISO 15189, ISO 13485, IVDR, HTA and HBS requirements in day-to-day practice, including SOP authorship, deviation/CAPA management, and audit readiness, so our lab remains inspection-ready and trusted. Clinical Trial Testing Support: Perform and oversee prospective diagnostic testing for clinical studies, ensuring GCP ICH adherence, sample integrity, accurate data capture, and dependable reporting timelines. Process Engineering and System Integration: Improve end-to-end laboratory workflows by integrating LIMS and related systems, enhancing data flow, operational efficiency, and robustness from assay development through clinical testing. Scientific Collaboration: Lead cross-functional scientific projects with clinical, laboratory, regulatory, and quality colleagues; articulate risks and mitigations clearly to align assay strategy with program objectives. Continuous Improvement and Scientific Innovation: Drive a culture of scientific excellence by assessing new tissue-based technologies and translating promising ideas into practical assay development plans that advance our oncology portfolio. Essential Skills/Experience: Degree in Biomedical Science, Pathology, Life Sciences, or a related discipline, or equivalent relevant experience. Strong practical experience in histology and immunohistochemistry (IHC) in a regulated laboratory environment. Experience supporting routine laboratory operations, including workflow coordination, sample handling, reagent readiness, and consumables management. Experience performing or overseeing prospective diagnostic testing or related clinical-study laboratory activities. Experience of laboratory information systems (LIMS/LIS) and digital pathology. Knowledge of relevant quality and compliance frameworks, including CAP/CLIA, ISO 15189, ISO 13485, ISO 14971, IVDR, HTA, and HBS, as applicable. Experience with controlled documentation, including SOPs, deviations, CAPAs, and audit/inspection readiness. Strong data integrity, documentation, and record-keeping skills. Strong communication and collaboration skills, with the ability to work effectively across cross-functional teams. Desirable Skills/Experience: HCPC registration, MIBMS or FIBMS, or equivalent professional accreditation. Experience in an accredited diagnostic laboratory, including CAP/CLIA or ISO 15189. Experience of digital systems integration in a pathology setting Experience leading analytical validation of histology or IHC-based assays. Familiarity with oncology precision medicine and companion/complementary diagnostics. Practical experience with HTA and HBS compliance in laboratory operations.Experience supporting audits, inspections, or accreditation activities. Experience working with external laboratories or diagnostic partners. Why AstraZeneca: Here, diagnostics shape the future of cancer care. You will work at the intersection of pathology, data science, and clinical development, advancing novel biomarkers and AI-enabled image analysis to identify patients who benefit most from our broad pipeline of new therapies. Expect to collaborate in unexpected combinations-scientists, engineers, and clinicians around the same slide image-translating rigorous laboratory science into real-world clinical impact. We pair bold goals with practical support, valuing curiosity and kindness alongside ambition, so you can move fast, learn deeply, and see your work change the practice of medicine. Date Posted 11-Aug-2026 Closing Date 29-Aug-2026 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Job Role: Principal Scientist - GMP Analytical Site: Chapel-en-le-Frith Salary:Competitive - DOE Job type: Permanent, full time (37.5 hrs per week) Overview Concept Life Sciences is seeking an experienced Principal Scientist (Analytical) to provide scientific leadership, and hands on expertise within our analytical function . This is a senior scientific role combining strategic influence, technical authority, and active laboratory contribution, supporting a diverse portfolio of client projects across small molecules and emerging modalities. You will act as a trusted scientific lead, driving high quality analytical delivery, and contributing to the continued growth and success of the department. What you will be doing: As a Principal Scientist (Analytical), you will shape and lead the analytical strategy across a diverse portfolio of client projects, combining hands on laboratory work with senior scientific leadership. You will design, execute, and interpret complex analytical studies, delivering high quality, compliant data that supports process development, technical investigations, and informed decision making. Working closely with R&D chemists, process chemists, project teams, quality colleagues, and clients, you will act as a trusted scientific partner, collaborating across disciplines to solve challenging technical problems and ensure analytical approaches are robust, fit for purpose, and where appropriate aligned with regulatory expectations. Alongside project delivery, you will model scientific excellence, uphold the highest standards of safety and quality, and actively mentor and develop colleagues, helping to strengthen analytical capability, innovation, and scientific culture across the organisation. About you: You will have broad technical knowledge of analytical techniques (e.g. UPLC-MS, SFC, NMR, GC MS), with the ability to provide practical support and scientific direction. You will be passionate about delivering high quality analytical science, combining hands on laboratory expertise with leadership to drive robust, compliant outcomes. Scientific integrity, data quality, safety, and regulatory compliance will be central to everything you do, alongside a strong focus on meeting client and project requirements. You will be a highly skilled analytical scientist with extensive experience in method development, validation, troubleshooting, and advanced characterisation techniques. You will act as a trusted scientific partner, working collaboratively to shape analytical strategy and solve complex technical challenges. You will enjoy mentoring and developing others, actively contributing to capability building, knowledge sharing, and a positive, inclusive scientific culture. You will hold a PhD (or equivalent postgraduate qualification) in a relevant scientific discipline, and ideally possess experience working in regulated (GMP) analytical laboratory environments. What you will get: In addition to a competitive salary, we provide generous holiday entitlement a pension scheme with enhanced employer contributions a health cash plan covering a range of therapy treatments a cycle to work scheme a retail discount scheme death in service benefit a discretionary bonus scheme free on site parking You'll also have access to our BHN Extras platform, offering cashback, discounts, and tech/home purchases via salary sacrifice. Colleague wellbeing is important to us - we offer 24/7 virtual GP access, emotional support services, and a comprehensive wellbeing hub. We're proud of our inclusive, supportive culture and provide a range of learning and development opportunities to help you grow both personally and professionally. About Concept Life Sciences: Concept Life Sciences is a multi-disciplined Contract Research Organisation based in the UK providing market leading scientific services globally. Over the past 25 years, Concept Life Sciences and its heritage companies have played a pivotal role in guiding numerous clients along their path to clinical success and many of these clients have evolved into enduring scientific collaborators. From our 4 sites across the UK, we provide world leading expertise to the pharmaceutical, biotech, agrochemical, and material science industries. We have clients across Europe, Asia, and the US, who value our knowledge based, science led, and customer focused approach.

Science Teacher - Supply Location: Hastings and surrounding areas Pay: £130-£180 per day for daily cover Pay to scale for long-term roles Job Type: Supply - Full-time or Part-time Start Date: September 2026 Science Teacher - Flexible Supply Work Are you a Science Teacher looking for flexible teaching work from September? We are recruiting Science Teachers to work with secondary schools throughout Hastings and the surrounding areas. We have opportunities for teachers seeking occasional supply days as well as those looking for regular or longer-term placements. Applications are welcome from teachers with a specialism in Biology, Chemistry or Physics, as well as those with experience teaching general Science. What the role involves Teaching Science across KS3 and KS4 Delivering practical and theory-based lessons Teaching GCSE Science where required Following existing schemes of work Planning lessons for longer-term placements Monitoring and assessing student progress Creating a positive and engaging classroom environment Managing behaviour effectively We are looking for: QTS or relevant teaching experience Secondary Science teaching experience Strong subject knowledge Confidence teaching to GCSE Good classroom management The ability to engage and motivate students Reliability and flexibility Why work with us? £130-£180 per day for daily cover Long-term roles paid to scale Full-time and part-time work Flexible supply opportunities Schools across Hastings and surrounding areas Support from a dedicated education recruitment consultant Apply today to explore the Science teaching opportunities available from September.

Select how often (in days) to receive an alert: Closing Date: 31 August :59 CET/CEST Directorate: Earth Observation Programmes Climate Application Scientist specialising in satellite remote sensing of the atmosphere, leading a dedicated portfolio of projects in ESA's Actionable Climate Information Section, Climate and Long-Term Action Division, Climate Action, Sustainability and Science Department, Directorate of Earth Observation Programmes. ESA's Actionable Climate Information Section is the focal point for the Agency's climate-related activities and is based at the European Centre for Space Applications and Telecommunications (ECSAT), situated on the Harwell Campus in Oxfordshire, United Kingdom. This ESA Section aims to increase the availability and use of global, satellite-based Earth observation data for climate-related science and decision-making. The United Nations Framework Convention on Climate Change (UNFCCC) drives international efforts to combat climate change by limiting global temperature rise to well below 2 degrees Celsius above pre-industrial levels, as set out in the Paris Agreement. In response to UNFCCC requirements for systematic monitoring of the climate system, ESA launched the Climate Change Initiative (CCI) research programme in 2008. Through CCI, ESA develops a suite of global climate data records of key components of the Earth system, known as Essential Climate Variables (ECVs). The climate quality datasets produced by CCI are a major contribution to the evidence base used to understand climate change and drive international action. Climate modellers use ECVs to study drivers, interactions and feedback due to climate change, as well as reservoirs, teleconnections, tipping points and fluxes of energy, water and carbon, and predict future change. The CCI also addresses the R&D required to support the UNFCCC Paris Agreement reporting requirements for signatories. Another major focus of the CCI is to connect climate observation and modelling communities through initiatives such as WCRP's CMIP and CORDEX. Reporting to the Head of the Actionable Climate Information Section, you will work to expand the availability, awareness, use and scientific impact of long-term satellite Earth observation (EO) data records for climate science and applications, with a main focus on the atmosphere, but also on other Earth system domains, as required by ESA. You will investigate and advise on the detailed scientific goals of the various international scientific and operational user communities concerned with international climate research, modelling, adaptation and mitigation activities. Your tasks and responsibilities will include: deriving technical specifications for EO-based information, mainly relating to the atmosphere's physical and chemical state and its interactions with the Earth's surface, with particular regard to the requirements of climate users, such as long-term stability, accuracy, consistency, availability, uncertainty characterisation and compatibility with climate observations from other space and non-space sources; establishing dialogue with specialised climate user communities, analysing their needs in terms of satellite-based observation of the climate system and assessing their feedback on available EO-based information; initiating and monitoring ESA R&D projects to respond to climate users' needs, such as enhancing capabilities to generate satellite-based climate data records for climate monitoring, reanalysis, modelling, attribution, projection, trend assessment and data assimilation; validating the results of such developments with the relevant climate users; promoting the use of EO data for supporting climate science, services and policies, such as the UNFCCC Global Stocktake commitments decided upon at COP 21, Paris, in 2015; cooperating with internal and external partners to maximise the benefits of ESA activities, such as maintaining links and ensuring coherence with relevant activities of ESA Member States and international partner organisations; contributing to the definition of ESA projects, work plans and programmes; contributing to ESA's public communications on EO; supporting the work of ESA Graduate Trainees and Research Fellows. Broad experience of satellite-based remote sensing retrieval techniques, in particular for retrieving the physical and chemical state of the atmosphere, validating retrieved quantities, and applying them in climate science Experience of science project management Knowledge of climate research, in particular related to the atmosphere and its interactions with the Earth's surface Knowledge of major international initiatives relating to Earth observation and climate research, such as UNFCCC, IPCC, the EU DGs, GCOS, WCRP, CEOS, CGMS and GEO, and their assessment and reporting mechanisms Knowledge of the international atmospheric science community and associated major international scientific research collaboration initiatives, preferably using space-based techniques Result Orientation Operational Efficiency Fostering Cooperation Relationship Management Continuous Improvement Forward Thinking A PhD in satellite-based monitoring of atmospheric physics/chemistry is required for this post, together with 4 years of relevant professional experience. Additional requirements At least four years' post-PhD work experience in relevant remote sensing application development, research, or another relevant area. A background in other Earth science domains, such as, land, ocean or cryosphere, would be an asset. Particular importance will be attached to your personal scientific ability, credibility among peers, flexibility and adaptability. You must be capable of working effectively in a team with minimum supervision, with excellent communication and presentation skills. Technical and computational knowledge, including in machine learning, applied to climate science would be an asset. You should be prepared to travel frequently in order to interact with the various relevant stakeholders. Diversity, Equity and Inclusiveness ESA is an equal opportunity employer, committed to achieving diversity within the workforce and creating an inclusive working environment. We therefore welcome applications from all qualified candidates irrespective of gender, sexual orientation, ethnicity, religious beliefs, age, disability or other characteristics. At the Agency we value diversity, and we welcome people with disabilities. Whenever possible, we seek to accommodate individuals with disabilities by providing the necessary support at the workplace. The Human Resources Department can also provide assistance during the recruitment process. If you would like to discuss this further, please contact us via email at Important Information and Disclaimer In principle, recruitment will be within the advertised grade band (A2-A4). However, if the selected candidate has less than four years of relevant professional experience following the completion of the master's degree, the position may be filled at A1 level. During the recruitment process, the Agency may request applicants to undergo selection tests. Additionally, successful candidates will need to undergo basic screening before appointment, which will be conducted by an external background screening service, in compliance with the European Space Agency's security procedures. Note that ESA is in the process of transitioning to a Matrix setup, which could lead to organisational changes affecting this position. The information published on ESA's careers website regarding working conditions is correct at the time of publication. It is not intended to be exhaustive and may not address all questions you would have. Nationality and Languages Please note that applications are only considered from nationals of one of the following States: Austria, Belgium, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Luxembourg, the Netherlands, Norway, Poland, Portugal, Romania, Slovenia, Spain, Sweden, Switzerland, the United Kingdom and Canada, Cyprus, Latvia, Lithuania and Slovakia. According to the ESA Convention, staff shall be recruited on the basis of their qualifications, taking into account an adequate distribution of posts among nationals of the Member States. The working languages of the Agency are English and French. A good knowledge of one of these is required. Knowledge of another Member State language would be an asset.

At LabGenius Therapeutics ("LabGenius"), our mission is to discover the next generation of therapeutic antibodies by combining human and machine intelligence. To do this, we've pioneered the development of EVA , state-of-the-art automated platform, enabling the closed-loop discovery of high-performing, non-intuitive antibody designs using proprietary, ML-grade datasets. For our wholly-owned therapeutic pipeline, we're using our closed-loop discovery engine to establish a pipeline of highly selective T-cell engagers and ADCs for the treatment of solid tumours. LabGenius has raised >£55M and is backed by top-tier investors, including M Ventures, Octopus Ventures, LG Corp, Atomico, Kindred Capital, Lux Capital and Obvious Ventures amongst others. The company is headquartered in London (UK) where we've established a cutting-edge antibody engineering facility. The company is staffed by a multidisciplinary team of more than 50 scientists and engineers. An experienced Translational Scientist with a strong background in clinical immunology to lead the clinical translation strategy for our advancing pipeline. This role focuses on the development, validation, and clinical implementation of biomarker and clinical PK/PD assays, as well as driving Companion Diagnostic (CDx) or patient stratification strategies. You will oversee the transition of assays into clinical grade tests, managing the internal technical transfer of mature assays from preclinical groups and directing the external tech transfer and scale up to clinical CROs, reference labs, and central laboratories globally. What you'll do in this role Clinical Assay Development: Oversee the development, optimization, and validation of robust clinical assays to measure T-cell engagement, peripheral B-cell/target-cell depletion, and soluble biomarkers (e.g., cytokine release panels, inflammatory markers). Vendor & Outsource Management: Audit, select, and manage relationships with specialized clinical CROs and diagnostic vendors, ensuring all transferred assays meet strict GxP and regulatory standards (FDA, IVDR, CLIA/CAP). Internal Clinical Tech Transfers: Partner with internal preclinical translational and discovery biology groups to pull mature, validated biomarker assays into the clinical translation workflow. Evaluate and adapt these assays to ensure they are fit for clinical compliance. External Clinical CRO Tech Transfers: Direct and manage the formal technical transfer of validated biomarker, PK/PD, and receptor occupancy (RO) assays from internal R&D to global clinical CROs, reference labs, and diagnostic partners. Ensure successful assay qualification, validation, and cross validation across multiple global testing sites. CDx & Stratification Strategy: Lead the development of Companion Diagnostics and clinical biomarker strategies tailored for IO and autoimmune therapies. Identify patient selection biomarkers (e.g., quantitative target expression, HLA typing, autoantibody profiles, baseline immune cell subset ratios) and drive CDx development through regulatory approval. Regulatory Report Writing & Review: Author and critically review assay validation plans, qualification reports, data transfer agreements (DTAs), and the biomarker/diagnostic sections of clinical protocols, Investigator Brochures (IBs), and regulatory filing documents (e.g., IND, NDA, PMA). What we're looking for Education: PhD in Immunology, Oncology, Molecular Diagnostics, or a related field with robust clinical translational experience in the biopharma industry. Bi directional Tech Transfer Expertise: Proven success in pulling assays from internal groups and executing formal, documented assay tech transfers to external clinical CROs, including defining acceptance criteria and managing external validation phases. Regulatory & Technical Documentation: Deep understanding of regulatory frameworks governing clinical assays alongside expert proficiency in writing and reviewing clinical study documents under GLP/GCP compliance. Immunology Knowledge: Solid grasp of clinical IO endpoints (e.g., iRECIST) and TCE specific clinical challenges (e.g., Cytokine Release Syndrome mitigation, target mediated drug disposition). Technical Platforms: Extensive experience with clinical assay modalities including multiplex Immunohistochemistry (mIHC/spatial biology), flow cytometry panels, Companion NGS panels, and high sensitivity immunoassay platforms. What you'll receive from us Aside from being part of our brilliant, purpose driven team, you'll also enjoy: Financial Discretionary performance linked annual bonus A generous stock option plan 3x Salary Life Insurance Health cash back plan on day to day health expenses Enhanced pension contribution, with an additional top up on tax savings from us via salary sacrifice Health Private Medical Insurance, including dental and optical Discounted gym membership through either AXA or Health Shield 24/7 access to GP Services Access to the Cycle to Work scheme: to make your commute cheaper, healthier and a whole lot greener Time Off 25 days annual leave (plus the bank holidays) Paid sick leave and income protection for long term leave Paid emergency leave so it doesn't eat into your relaxation time Paid bereavement leave Moving home day Wellbeing Employee Assistance Programme including access to coaching and CBT sessions Team building Weekly team lunches through Feedr. A programme of social events both company wide and within your own teams Diversity & Inclusion We believe that diversity makes for innovative, exceptional teams. We are an equal opportunity employer and do not discriminate based on gender, race, colour, religion or belief, national origin, age, sexual orientation, marital status, disability, or any other protected class. If you don't feel like you meet every single requirement of this role, we still want to hear from you! We encourage you to apply, have a discussion with us about the role or others that we may have at LabGenius either now or in the future, together we can build more inclusive workplaces.

Select how often (in days) to receive an alert: We are one of the leading European contract manufacturers in the pharmaceutical, biotech and healthcare sectors, with some 2,300 employees in Germany, France, Finland, UK and Norway. For us, the next step is always the one that matters most. Our fast pace drives us forward, fills our working environment with life and spurs our growth. Our winning formula for shared success: room for passion. Because we know that passion is the best medicine when it comes to excellent service around the world. Welcome to NextPharma. Job Purpose: To support the production of both development and market finished products under GMP conditions in all areas of quality control and calibration. Key responsibilities and accountabilities: Work as part of a team alongside Production and other analytical departments including development and stability . Actively involved in performing analytical activities to determine fitness for purpose of starting materials, intermediate and finished products Technically competent in analytical activities (e.g., pharmacopeial wet chemistry, HPLC, GC, Dissolution) for QC testing of raw materials, packaging components and finished products. All activities to be performed under current cGMP, In house SOP's and/or pharmacopoeia Perform sampling of starting materials, packaging components and finished products Perform cleaning verification analysis to assure suitability of Production equipment for subsequent use Support calibration of key analytical equipment and measuring devices used in or on production equipment Comply with company health and safety procedures. Personality: Results oriented with a positive outlook and clear focus on high quality output: Solid planning and organizational ability; Reliable, tolerant, and dependable: Comfortable dealing with senior managers and customers: Enjoy working in a fast, stimulating environment. Goal-oriented: Able to work under pressure and meet deadlines; Excellent communication/ presentation skills. Able to get on with others and be a team player but equally comfortable working independently. Personal Situation Flexible and able to work extended hours when required. Specific Job Skills: Required: An understanding of drug development and manufacturing processes Demonstrated technical competence of the technical and practical skills involved in analytical activities to prescribed quality standards Skilled in analytical techniques e.g., HPLC, Dissolution, Gas Chromatography, and wet chemistry techniques Able to communicate well with others, both laboratory and non-laboratory based Able to work with minimal supervision. Good understanding of quality control, SOP and GMP adherence Have a broad knowledge with and experience of working within a cGMP/GLP environment. Experience of working within a pharmaceutical or biotechnology industry Ability to work to key regulatory and compliance requirements Experience of quality control within a pharmaceutical environment Experience of Chromeleon software Experience of data reporting and checking data within a QC environment Understand and demonstrate a pragmatic approach to problem solving with GMP constraints. Computer skills: Must be competent in the use of MS Office, particularly Excel and Word, e-mail and internet. Previous use of chromatographic acquisition software is desired but not essential. Literacy and Numeracy: Must be competent in writing reports both for internal use and for customers. Must be competent in the interpretation of analytical data. Business Presentation Skills Must be an excellent face-to-face and telephone communicator. It's time for your next chapter: We look forward to receiving your application.