GlaxoSmithKline
Gateshead, Tyne And Wear
Site Name: UK - County Durham - Barnard Castle Posted Date: Dec 2 2025 GSK Barnard Castle is a key secondary manufacturing site and has invested heavily in industry 4.0 state of the art, bespoke equipment to support sustained new product introductions and volume increases, and as a key supplier of some of GSK's blockbuster products, the site contributes revenues of $2Bn annually. We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme. We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work. Discover more about our company wide benefits and life at GSK on our webpage Life at GSK GSK The Sterility Assurance Facility Manager leads sterility assurance projects and has overall oversight of facilities within their areas of responsibility, ensuring compliance with regulatory requirements and industry standards. This role drives contamination control strategies (CCS), ensures the implementation of sterility assurance measures across site facilities, and collaborates with operations to ensure the consistent application of sterility assurance requirements. In this role you will Lead sterility assurance projects to ensure contamination control strategies (CCS) are effectively implemented and aligned with site objectives and regulatory requirements. Provide overall oversight of facility operations, ensuring compliance with sterility assurance standards and contamination control measures. Drive the implementation of sterility assurance programmes across facilities, collaborating with cross-functional teams site and above site teams to ensure consistency and effectiveness. Ensure facilities are maintained and operated in alignment with industry best practices, regulatory requirements, and contamination prevention principles. Collaborate with operations and quality teams to ensure contamination control measures are integrated effectively into manufacturing processes. Monitor performance metrics related to facility operations and contamination control, identifying areas for improvement and implementing corrective actions as needed. Act as the primary point of contact for sterility assurance within facilities, representing the team during audits, inspections, and internal reviews. Contribute to the harmonisation and continuous improvement of sterility assurance practices across the organisation, sharing knowledge and best practices. Develop and deliver training programmes, ensuring staff understand and consistently apply sterility assurance and contamination control measures. Support the strategic planning and execution of facility upgrades or projects to optimise contamination control systems and ensure regulatory compliance. Why you? Basic Qualifications & Skills: Bachelor's degree in Chemistry, Biochemistry, Microbiology, or a related field Significant experience in sterility assurance within the pharmaceutical, biotechnology, or related industry Strong knowledge of regulatory requirements around sterility assurance and sterile manufacturing (e.g., FDA, MHRA, EMA) and industry standards (e.g., cGMP, ISO). Excellent problem-solving skills and attention to detail. Strong leadership and project management abilities. Effective communication and interpersonal skills. Preferred Qualifications & Skills: An advanced degree in Chemistry, Biochemistry, Microbiology, or a related field provides advanced knowledge of the scientific principles and methodologies that are crucial for ensuring product quality in the pharmaceutical industry. Closing Date: Closing Date: 16th December 2025 (COB) Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or . The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.
Site Name: UK - County Durham - Barnard Castle Posted Date: Dec 2 2025 GSK Barnard Castle is a key secondary manufacturing site and has invested heavily in industry 4.0 state of the art, bespoke equipment to support sustained new product introductions and volume increases, and as a key supplier of some of GSK's blockbuster products, the site contributes revenues of $2Bn annually. We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme. We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work. Discover more about our company wide benefits and life at GSK on our webpage Life at GSK GSK The Sterility Assurance Facility Manager leads sterility assurance projects and has overall oversight of facilities within their areas of responsibility, ensuring compliance with regulatory requirements and industry standards. This role drives contamination control strategies (CCS), ensures the implementation of sterility assurance measures across site facilities, and collaborates with operations to ensure the consistent application of sterility assurance requirements. In this role you will Lead sterility assurance projects to ensure contamination control strategies (CCS) are effectively implemented and aligned with site objectives and regulatory requirements. Provide overall oversight of facility operations, ensuring compliance with sterility assurance standards and contamination control measures. Drive the implementation of sterility assurance programmes across facilities, collaborating with cross-functional teams site and above site teams to ensure consistency and effectiveness. Ensure facilities are maintained and operated in alignment with industry best practices, regulatory requirements, and contamination prevention principles. Collaborate with operations and quality teams to ensure contamination control measures are integrated effectively into manufacturing processes. Monitor performance metrics related to facility operations and contamination control, identifying areas for improvement and implementing corrective actions as needed. Act as the primary point of contact for sterility assurance within facilities, representing the team during audits, inspections, and internal reviews. Contribute to the harmonisation and continuous improvement of sterility assurance practices across the organisation, sharing knowledge and best practices. Develop and deliver training programmes, ensuring staff understand and consistently apply sterility assurance and contamination control measures. Support the strategic planning and execution of facility upgrades or projects to optimise contamination control systems and ensure regulatory compliance. Why you? Basic Qualifications & Skills: Bachelor's degree in Chemistry, Biochemistry, Microbiology, or a related field Significant experience in sterility assurance within the pharmaceutical, biotechnology, or related industry Strong knowledge of regulatory requirements around sterility assurance and sterile manufacturing (e.g., FDA, MHRA, EMA) and industry standards (e.g., cGMP, ISO). Excellent problem-solving skills and attention to detail. Strong leadership and project management abilities. Effective communication and interpersonal skills. Preferred Qualifications & Skills: An advanced degree in Chemistry, Biochemistry, Microbiology, or a related field provides advanced knowledge of the scientific principles and methodologies that are crucial for ensuring product quality in the pharmaceutical industry. Closing Date: Closing Date: 16th December 2025 (COB) Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or . The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.
Jazz Pharmaceuticals
Cambridge, Cambridgeshire
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Job Role: We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team. Key Responsibilities: Utilize modern molecular modelling methods to support different stages of R&D programs. Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates. Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables. Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours. Set the vision and strategy for computational chemistry. Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry. Manage CRO compchem activities, providing expertise and guidance. Present plans and results internally, including at board level, and externally at conferences. Contribute to the writing of patent applications, scientific publications, and internal reports. Develop and mentor less experienced staff. Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies. Undertake ongoing professional development by attending relevant training and conferences. Requirements & Qualifications: MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting. Expert knowledge in CADD software packages and modern molecular modelling techniques. Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies. Passion for drug discovery with a deep entrepreneurial and problem-solving attitude. Mastery of all the theoretical and practical principles of medicinal chemistry and drug design. Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process. In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems. Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame. Demonstrated track record of scientific publications. Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Job Role: We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team. Key Responsibilities: Utilize modern molecular modelling methods to support different stages of R&D programs. Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates. Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables. Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours. Set the vision and strategy for computational chemistry. Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry. Manage CRO compchem activities, providing expertise and guidance. Present plans and results internally, including at board level, and externally at conferences. Contribute to the writing of patent applications, scientific publications, and internal reports. Develop and mentor less experienced staff. Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies. Undertake ongoing professional development by attending relevant training and conferences. Requirements & Qualifications: MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting. Expert knowledge in CADD software packages and modern molecular modelling techniques. Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies. Passion for drug discovery with a deep entrepreneurial and problem-solving attitude. Mastery of all the theoretical and practical principles of medicinal chemistry and drug design. Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process. In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems. Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame. Demonstrated track record of scientific publications. Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
