Upperton Pharma Solutions is a Nottingham-based CDMO that specialises in the development and manufacture of pharmaceutical products, providing a complete service from early-stage feasibility to GMP clinical manufacture. Formulations cover a range of delivery routes, typically including oral (tablets & capsules), nasal and inhaled. Continued growth and investment into the business has led to the creation of exciting new job opportunities; in our new GMP Manufacturing headquarters in Beeston, Nottingham. Upperton Pharma Solutions is undergoing a period of significant expansion to meet international customer demand and offer a comprehensive drug development portfolio, so now is a great time to join our team. The role: Reporting to the QC Manager the QC Senior Scientist I will be directly involved in all aspects of analytical testing. The job holder will be expected to work to cGMP and regulatory requirements and to support client projects from initial proposal to completion. They will be expected to lead analytical aspects of a project and ensure client timelines are met. Main duties and responsibilities: Lead analytical aspects of a project as directed and provide analytical updates to projects during internal and external project meetings as required. Support and supervise analytical staff and the QC Manager in analytical project-based activities, providing leadership and technical support in laboratory activities. Ensure accurate completion of analytical records relating to analytical projects and quality control activities including supporting documentation such as SOPs and risk assessments. Contribute to writing and reviewing analytical protocols and reports as directed. Support the leadership team in ensuring all analytical equipment and laboratory processes are compliant to cGMP and regulatory and customer requirements. Support and lead activities such as LIR's, deviations, CAPA's, change controls. Overseeing client meetings involving QC data, project issues and documentation (protocols, specifications and Certificates of Analysis) General role responsibilities: Understand & follow the company's Health & Safety Policy & Procedures & report all accidents or any unsafe conditions in the workplace. Ensure training has been received before undertaking specific duties & that all training is recorded in training records. Adhere to all HR policies & procedures, specifically including all absence policies and procedures. Communicate within your own department and cross departmental (QA, Manufacturing, R&D) to ensure that all relevant information is forwarded to the appropriate personnel on a regular & timely basis. Responsible for a small number of direct reports, to provide support and guidance to them, perform 1:1s, performance reviews and objective allocations. Perform analytical testing as required including but not limited to HPLC, GC, KF and Dissolution. Review and approval of analytical data Essential Skills and experience: Be educated to degree level or equivalent experience in a related scientific/technical discipline. Extensive experience in industry within a GxP laboratory environment, with practical experience of pharmaceutical analysis using HPLC and/or UPLC methods. Experience working to, and a strong understanding of GMP, GLP, and ICH guidelines. Have excellent communication skills (written and verbal), and proficiency in the use of Microsoft Office applications. Ability to operate in a flexible manner and handling a diverse workload. Positive attitude, autonomous working manner and able to work as part of a large team. Impeccable attention to detail, and excellent organisation, time management and a good documentation practice. Proficiency in chromatographic software Chromeleon. Understanding of safe working practices within a laboratory setting. GC and ELISA experience desirable. Experience with mentoring and training (desirable). Equipment validation experience (IQ, OQ, PQ)(desirable). Working with sterile products (desirable). What you will get in return: We offer employees not only a competitive salary but also an excellent suite of benefits including: 25 days holiday and your birthday off! Company contributory pension package Life insurance Private Medical Insurance through Vitality Internal and external training courses and professional development support Free onsite car parking We know it is the little things that make every day special, so we also organise employee events for you to attend throughout the year, like our annual Christmas party, summer party and charity fund raising events.
Mar 12, 2026
Full time
Upperton Pharma Solutions is a Nottingham-based CDMO that specialises in the development and manufacture of pharmaceutical products, providing a complete service from early-stage feasibility to GMP clinical manufacture. Formulations cover a range of delivery routes, typically including oral (tablets & capsules), nasal and inhaled. Continued growth and investment into the business has led to the creation of exciting new job opportunities; in our new GMP Manufacturing headquarters in Beeston, Nottingham. Upperton Pharma Solutions is undergoing a period of significant expansion to meet international customer demand and offer a comprehensive drug development portfolio, so now is a great time to join our team. The role: Reporting to the QC Manager the QC Senior Scientist I will be directly involved in all aspects of analytical testing. The job holder will be expected to work to cGMP and regulatory requirements and to support client projects from initial proposal to completion. They will be expected to lead analytical aspects of a project and ensure client timelines are met. Main duties and responsibilities: Lead analytical aspects of a project as directed and provide analytical updates to projects during internal and external project meetings as required. Support and supervise analytical staff and the QC Manager in analytical project-based activities, providing leadership and technical support in laboratory activities. Ensure accurate completion of analytical records relating to analytical projects and quality control activities including supporting documentation such as SOPs and risk assessments. Contribute to writing and reviewing analytical protocols and reports as directed. Support the leadership team in ensuring all analytical equipment and laboratory processes are compliant to cGMP and regulatory and customer requirements. Support and lead activities such as LIR's, deviations, CAPA's, change controls. Overseeing client meetings involving QC data, project issues and documentation (protocols, specifications and Certificates of Analysis) General role responsibilities: Understand & follow the company's Health & Safety Policy & Procedures & report all accidents or any unsafe conditions in the workplace. Ensure training has been received before undertaking specific duties & that all training is recorded in training records. Adhere to all HR policies & procedures, specifically including all absence policies and procedures. Communicate within your own department and cross departmental (QA, Manufacturing, R&D) to ensure that all relevant information is forwarded to the appropriate personnel on a regular & timely basis. Responsible for a small number of direct reports, to provide support and guidance to them, perform 1:1s, performance reviews and objective allocations. Perform analytical testing as required including but not limited to HPLC, GC, KF and Dissolution. Review and approval of analytical data Essential Skills and experience: Be educated to degree level or equivalent experience in a related scientific/technical discipline. Extensive experience in industry within a GxP laboratory environment, with practical experience of pharmaceutical analysis using HPLC and/or UPLC methods. Experience working to, and a strong understanding of GMP, GLP, and ICH guidelines. Have excellent communication skills (written and verbal), and proficiency in the use of Microsoft Office applications. Ability to operate in a flexible manner and handling a diverse workload. Positive attitude, autonomous working manner and able to work as part of a large team. Impeccable attention to detail, and excellent organisation, time management and a good documentation practice. Proficiency in chromatographic software Chromeleon. Understanding of safe working practices within a laboratory setting. GC and ELISA experience desirable. Experience with mentoring and training (desirable). Equipment validation experience (IQ, OQ, PQ)(desirable). Working with sterile products (desirable). What you will get in return: We offer employees not only a competitive salary but also an excellent suite of benefits including: 25 days holiday and your birthday off! Company contributory pension package Life insurance Private Medical Insurance through Vitality Internal and external training courses and professional development support Free onsite car parking We know it is the little things that make every day special, so we also organise employee events for you to attend throughout the year, like our annual Christmas party, summer party and charity fund raising events.
Senior Product Engineer (AWS Serverless, TypeScript, Node) Location: Manchester / Hybrid (2 times a week in the office) Salary: Up to £85,000 (DOE) Sector: HeathTech About the Opportunity How would you like to work on products designed to improve people's lives? This is an opportunity for a Senior Software Engineer to join a Tech for Good business in Manchester as they embark on an ambitious roadmap of new products and services. They are looking for an experienced Software Engineer with a Product and Commercial mindset to help drive the next phase of their platform evolution. This will get you excited if you're a 'product builder' with a 'You Build It, You Run It' mindset. It's a company where your voice is heard, giving you the opportunity to shape the product. You'll understand business needs will be able to adapt quickly. It's a key role with a focus on delivering modern, API-driven solutions that power their product ecosystem. You'll have experience in the follow: Strong backend development experience with TypeScript/Node or Python. Deep experience with API design, client-server systems, and distributed architectures. Hands-on experience with message queues and asynchronous system design. Knowledge of cloud services (AWS preferred, but Azure/GCP also fine- easy to transition). Solid understanding of logging, monitoring, security considerations, and modern DevOps practices. Background in enterprise-level engineering or building production-grade systems. Experience with serverless (Lambda or equivalent). CI/CD knowledge and infrastructure-as-code concepts (e.g., Terraform). Strong interest in improving systems holistically - architecture, performance, security. This is an opportunity to join an ethically sound business that is genuinely trying to improve people's health. There is a broad technical scope - backend engineering, cloud, distributed systems and integrations - and a role with influence and room to grow. Interview Process Initial meet & greet Technical Interview Final interview / offer If you are a Senior Software Engineer and looking to work with cutting edge technology, in a scaling and successful company that cares about ethics, then please apply today!
Mar 12, 2026
Full time
Senior Product Engineer (AWS Serverless, TypeScript, Node) Location: Manchester / Hybrid (2 times a week in the office) Salary: Up to £85,000 (DOE) Sector: HeathTech About the Opportunity How would you like to work on products designed to improve people's lives? This is an opportunity for a Senior Software Engineer to join a Tech for Good business in Manchester as they embark on an ambitious roadmap of new products and services. They are looking for an experienced Software Engineer with a Product and Commercial mindset to help drive the next phase of their platform evolution. This will get you excited if you're a 'product builder' with a 'You Build It, You Run It' mindset. It's a company where your voice is heard, giving you the opportunity to shape the product. You'll understand business needs will be able to adapt quickly. It's a key role with a focus on delivering modern, API-driven solutions that power their product ecosystem. You'll have experience in the follow: Strong backend development experience with TypeScript/Node or Python. Deep experience with API design, client-server systems, and distributed architectures. Hands-on experience with message queues and asynchronous system design. Knowledge of cloud services (AWS preferred, but Azure/GCP also fine- easy to transition). Solid understanding of logging, monitoring, security considerations, and modern DevOps practices. Background in enterprise-level engineering or building production-grade systems. Experience with serverless (Lambda or equivalent). CI/CD knowledge and infrastructure-as-code concepts (e.g., Terraform). Strong interest in improving systems holistically - architecture, performance, security. This is an opportunity to join an ethically sound business that is genuinely trying to improve people's health. There is a broad technical scope - backend engineering, cloud, distributed systems and integrations - and a role with influence and room to grow. Interview Process Initial meet & greet Technical Interview Final interview / offer If you are a Senior Software Engineer and looking to work with cutting edge technology, in a scaling and successful company that cares about ethics, then please apply today!
About AQEMIA AQEMIA is a drug invention company dedicated to creating entirely new medicines to address major unmet medical needs. At the core of our mission is QEMI, our proprietary molecule-invention platform, which uniquely combines cutting edge science with advanced technology. Powered by physics based modeling, statistical mechanics, and generative AI, QEMI allows our teams to design novel drug candidates from first principles. What makes AQEMIA different is our commitment to true innovation: our research is dedicated to the invention of new molecular entities, not the refinement of existing ones. We focus on inventing never before seen molecules, without relying on experimental data, and advancing them into a growing pipeline of proprietary programs and strategic partnerships with leading pharmaceutical companies. Our most advanced preclinical programs are currently in vivo optimization, targeting diseases still waiting for effective treatments, offering our teams the opportunity to work on science that can make a real difference in people's lives. For more information, visit and LinkedIn. About our Team AQEMIA brings together a diverse, multidisciplinary team of 65+ professionals based in Paris and London. Our scientists and engineers, including chemists, physicists, machine learning experts, and software engineers, work side by side to push the boundaries of early stage drug discovery. This close collaboration across disciplines is central to our approach, enabling us to tackle complex scientific challenges from first principles and translate cutting edge ideas into novel therapeutic candidates. At AQEMIA, team members are encouraged to contribute their expertise, learn from one another, and play an active role in shaping the future of drug invention. About the Team The mission of the Molecular Simulations Team is threefold: Support drug discovery programs by maximizing the impact of binding free energy calculations in decision making. Build, benchmark and continuously improve reproducible and scalable pipelines for binding free energy calculations, enabling support for multiple programs in parallel. Collaborate closely with our Physics Research Team to integrate innovations from Aqemia's proprietary binding free energy methods. Role Overview As a Senior Application Scientist in the Molecular Simulations Team, you will be a scientific leader and technical expert, contributing to the strategy and delivery of Aqemia's Binding Free Energy Technology. You will help define and evolve how physics based simulations inform and accelerate drug discovery decisions at Aqemia. Key Responsibilities Design and lead large scale simulation studies (e.g., relative and absolute binding free energy predictions). Evaluate and improve modeling protocols for reproducibility, accuracy, and efficiency. Serve as a mentor to junior scientists, promoting best practices in simulation and analysis. Contribute to cross functional planning and the integration of simulations with experimental and AI based insights. Stay at the forefront of developments in molecular simulations and suggest innovations to the team. Support the development and scaling of workflows that can serve multiple drug discovery projects. Work closely with the Research Team to implement improvements and updates to Aqemia's proprietary binding free energy methods. Qualifications & Experience MSc or PhD in Computational Chemistry, Biophysics, Statistical Mechanics, or related discipline. 5+ years of experience in molecular simulations, ideally within a drug discovery context. Deep knowledge of free energy methods, molecular dynamics, and simulation software. Strong programming/scripting ability and experience with workflow automation. Demonstrated ability to lead scientific projects and communicate effectively across disciplines. Nice to Have Experience in machine learning applications for physics based modeling. Track record of scientific publications and contributions to the computational drug discovery community. Preferred Mindset Scientific Rigour: Champion high scientific standards and promote best practices across the team. Humble and Willing to Learn: Lead by example with curiosity and openness to new ideas. Excited by Challenging Scientific Problems: Passionate about solving complex, cutting edge problems and guiding others through them. Pragmatic and Impact Driven: Combine strategic thinking with practical execution to deliver real world impact in a fast paced environment. Leadership through Influence: Inspire and mentor colleagues while fostering a collaborative, high performance culture. Why Join Us? At AQEMIA, we work for a mission: joining us means having your own impact on changing the way drugs are discovered, and helping to shape the direction of our fast growing company and team. Expanding Drug Discovery Pipeline Focused on critical therapeutic areas like Oncology, CNS, Immuno inflammation with in vivo proof of concept/patent stage programs. Collaborations with top Pharma, including a $140M Sanofi deal. World Class Interdisciplinary Team Work alongside exceptional talent at the intersection of technology and life sciences. Our teams combine deep expertise in AI, physics based modeling, biology, and medicinal chemistry to push the boundaries of innovation. DeepTech Recognition AQEMIA is proud to be part of the French Tech 120 and France 2030, highlighting our role as a key player in Europe's DeepTech ecosystem. Prime Location with Flexibility Our offices are located in the heart of Paris and London (King's Cross), with flexible work arrangements including up to two remote days per week. Strong Financial Backing $100M raised from leading European and International investors.
Mar 12, 2026
Full time
About AQEMIA AQEMIA is a drug invention company dedicated to creating entirely new medicines to address major unmet medical needs. At the core of our mission is QEMI, our proprietary molecule-invention platform, which uniquely combines cutting edge science with advanced technology. Powered by physics based modeling, statistical mechanics, and generative AI, QEMI allows our teams to design novel drug candidates from first principles. What makes AQEMIA different is our commitment to true innovation: our research is dedicated to the invention of new molecular entities, not the refinement of existing ones. We focus on inventing never before seen molecules, without relying on experimental data, and advancing them into a growing pipeline of proprietary programs and strategic partnerships with leading pharmaceutical companies. Our most advanced preclinical programs are currently in vivo optimization, targeting diseases still waiting for effective treatments, offering our teams the opportunity to work on science that can make a real difference in people's lives. For more information, visit and LinkedIn. About our Team AQEMIA brings together a diverse, multidisciplinary team of 65+ professionals based in Paris and London. Our scientists and engineers, including chemists, physicists, machine learning experts, and software engineers, work side by side to push the boundaries of early stage drug discovery. This close collaboration across disciplines is central to our approach, enabling us to tackle complex scientific challenges from first principles and translate cutting edge ideas into novel therapeutic candidates. At AQEMIA, team members are encouraged to contribute their expertise, learn from one another, and play an active role in shaping the future of drug invention. About the Team The mission of the Molecular Simulations Team is threefold: Support drug discovery programs by maximizing the impact of binding free energy calculations in decision making. Build, benchmark and continuously improve reproducible and scalable pipelines for binding free energy calculations, enabling support for multiple programs in parallel. Collaborate closely with our Physics Research Team to integrate innovations from Aqemia's proprietary binding free energy methods. Role Overview As a Senior Application Scientist in the Molecular Simulations Team, you will be a scientific leader and technical expert, contributing to the strategy and delivery of Aqemia's Binding Free Energy Technology. You will help define and evolve how physics based simulations inform and accelerate drug discovery decisions at Aqemia. Key Responsibilities Design and lead large scale simulation studies (e.g., relative and absolute binding free energy predictions). Evaluate and improve modeling protocols for reproducibility, accuracy, and efficiency. Serve as a mentor to junior scientists, promoting best practices in simulation and analysis. Contribute to cross functional planning and the integration of simulations with experimental and AI based insights. Stay at the forefront of developments in molecular simulations and suggest innovations to the team. Support the development and scaling of workflows that can serve multiple drug discovery projects. Work closely with the Research Team to implement improvements and updates to Aqemia's proprietary binding free energy methods. Qualifications & Experience MSc or PhD in Computational Chemistry, Biophysics, Statistical Mechanics, or related discipline. 5+ years of experience in molecular simulations, ideally within a drug discovery context. Deep knowledge of free energy methods, molecular dynamics, and simulation software. Strong programming/scripting ability and experience with workflow automation. Demonstrated ability to lead scientific projects and communicate effectively across disciplines. Nice to Have Experience in machine learning applications for physics based modeling. Track record of scientific publications and contributions to the computational drug discovery community. Preferred Mindset Scientific Rigour: Champion high scientific standards and promote best practices across the team. Humble and Willing to Learn: Lead by example with curiosity and openness to new ideas. Excited by Challenging Scientific Problems: Passionate about solving complex, cutting edge problems and guiding others through them. Pragmatic and Impact Driven: Combine strategic thinking with practical execution to deliver real world impact in a fast paced environment. Leadership through Influence: Inspire and mentor colleagues while fostering a collaborative, high performance culture. Why Join Us? At AQEMIA, we work for a mission: joining us means having your own impact on changing the way drugs are discovered, and helping to shape the direction of our fast growing company and team. Expanding Drug Discovery Pipeline Focused on critical therapeutic areas like Oncology, CNS, Immuno inflammation with in vivo proof of concept/patent stage programs. Collaborations with top Pharma, including a $140M Sanofi deal. World Class Interdisciplinary Team Work alongside exceptional talent at the intersection of technology and life sciences. Our teams combine deep expertise in AI, physics based modeling, biology, and medicinal chemistry to push the boundaries of innovation. DeepTech Recognition AQEMIA is proud to be part of the French Tech 120 and France 2030, highlighting our role as a key player in Europe's DeepTech ecosystem. Prime Location with Flexibility Our offices are located in the heart of Paris and London (King's Cross), with flexible work arrangements including up to two remote days per week. Strong Financial Backing $100M raised from leading European and International investors.
Job Title: Senior Software Engineer (Full Stack) Salary: £80k-£100k + Equity Company Description: Humaans - YC-backed AI platform for workplace orchestration Job Description: Join a high-performance team building Athena, an agentic AI layer redefining HR infrastructure. You will own features end-to-end across a modern TypeScript stack, moving beyond simple data management into intelligent orchestration. Working directly with the founders, you'll solve complex problems for global customers like Poolside and Quantexa in a fast-scaling environment. Location: London, UK Why this role is remarkable: Work at the forefront of the AI transition in HR tech, building a differentiated platform backed by $20M from the founders of Slack, Figma, and Shopify. High-leverage environment where engineers aren't just handed specs; you'll partner with the CEO and Head of Engineering to shape product strategy and technical architecture. Exceptional engineering culture with a 5-year equity exercise window, top-tier private healthcare, and a small, elite team that prioritizes quality and craftsmanship. What you will do: Develop and scale end-to-end features using TypeScript, React, Node.js, and Postgres, deployed via Kubernetes on Google Cloud Platform. Architect and expand a public REST API and real-time WebSocket infrastructure to support a growing marketplace of third-party integrations. Collaborate deeply with product and design teams to translate complex workforce data models into reliable, AI-driven automation workflows for global enterprises. The ideal candidate: Extensive industry experience in full-stack SaaS development with deep proficiency in Node.js and a strong appreciation for TypeScript. Proven track record of taking ownership of vague product problems and driving them to high-quality, customer-ready releases in a fast-paced startup. Strong product sense and design craftsmanship, with the ability to balance technical excellence with pragmatic business trade-offs and user impact.
Mar 12, 2026
Full time
Job Title: Senior Software Engineer (Full Stack) Salary: £80k-£100k + Equity Company Description: Humaans - YC-backed AI platform for workplace orchestration Job Description: Join a high-performance team building Athena, an agentic AI layer redefining HR infrastructure. You will own features end-to-end across a modern TypeScript stack, moving beyond simple data management into intelligent orchestration. Working directly with the founders, you'll solve complex problems for global customers like Poolside and Quantexa in a fast-scaling environment. Location: London, UK Why this role is remarkable: Work at the forefront of the AI transition in HR tech, building a differentiated platform backed by $20M from the founders of Slack, Figma, and Shopify. High-leverage environment where engineers aren't just handed specs; you'll partner with the CEO and Head of Engineering to shape product strategy and technical architecture. Exceptional engineering culture with a 5-year equity exercise window, top-tier private healthcare, and a small, elite team that prioritizes quality and craftsmanship. What you will do: Develop and scale end-to-end features using TypeScript, React, Node.js, and Postgres, deployed via Kubernetes on Google Cloud Platform. Architect and expand a public REST API and real-time WebSocket infrastructure to support a growing marketplace of third-party integrations. Collaborate deeply with product and design teams to translate complex workforce data models into reliable, AI-driven automation workflows for global enterprises. The ideal candidate: Extensive industry experience in full-stack SaaS development with deep proficiency in Node.js and a strong appreciation for TypeScript. Proven track record of taking ownership of vague product problems and driving them to high-quality, customer-ready releases in a fast-paced startup. Strong product sense and design craftsmanship, with the ability to balance technical excellence with pragmatic business trade-offs and user impact.
Own and shape the end to end technical architecture of the Payments Platform, ensuring scalability, resilience, and regulatory compliance. Act as design authority for complex and high risk payments initiatives across multiple squads and domains. Define and enforce engineering standards, reference architectures, and non functional requirements (availability, latency, throughput, security). Lead technical decisions across multi rail payments (e.g. real time, high value, cross border) and platform capabilities such as orchestration, clearing, and settlement. Embed security, controls, and operational resilience by design, partnering closely with Risk, Cyber, and Controls teams. Drive modernisation and platform evolution, reducing technical debt and enabling faster product and client onboarding. Provide technical leadership and mentorship to senior engineers, tech leads, and architects across Payments Technology. Influence delivery and outcomes without direct line management, acting as a trusted advisor to senior technology and business leaders. Ensure high standards of engineering quality, including test strategy, CI/CD, observability, and incident learnings. Purpose of the role To lead and manage engineering teams, providing technical guidance, mentorship, and support to ensure the delivery of high-quality software solutions, driving technical excellence, fostering a culture of innovation, and collaborating with cross-functional teams to align technical decisions with business objectives. Accountabilities Lead engineering teams effectively, fostering a collaborative and high-performance culture to achieve project goals and meet organizational objectives. Oversee timelines, team allocation, risk management and task prioritization to ensure the successful delivery of solutions within scope, time, and budget. Mentor and support team members' professional growth, conduct performance reviews, provide actionable feedback, and identify opportunities for improvement. Evaluation and enhancement of engineering processes, tools, and methodologies to increase efficiency, streamline workflows, and optimize team productivity. Collaboration with business partners, product managers, designers, and other stakeholders to translate business requirements into technical solutions and ensure a cohesive approach to product development. Enforcement of technology standards, facilitate peer reviews, and implement robust testing practices to ensure the delivery of high-quality solutions. Director Expectations To manage a business function, providing significant input to function wide strategic initiatives. Contribute to and influence policy and procedures for the function and plan, manage and consult on multiple complex and critical strategic projects, which may be business wide They manage the direction of a large team or sub-function, leading other people managers and embedding a performance culture aligned to the values of the business. Or for an individual contributor, they lead organisation wide projects and act as deep technical expert and thought leader, identifying new ways of working and collaborating cross functionally. They will train, guide and coach less experienced specialists and provide information affecting long term profits, organisational risks and strategic decisions Provide expert advice to senior functional management and committees to influence decisions made outside of own function, offering significant input to function wide strategic initiatives. Manage, coordinate and enable resourcing, budgeting and policy creation for a significant sub-function. Escalates breaches of policies / procedure appropriately. Foster and guide compliance, ensure regulations are observed that relevant processes in place to facilitate adherence. Focus on the external environment, regulators, or advocacy groups to both monitor and influence on behalf of Barclays, when appropriate. Demonstrate extensive knowledge of how the function integrates with the business division / Group to achieve the overall business objectives. Maintain broad and comprehensive knowledge of industry theories and practices within own discipline alongside up-to-date relevant sector / functional knowledge, and insight into external market developments / initiatives. Use interpretative thinking and advanced analytical skills to solve problems and design solutions in often complex/ sensitive situations. Exercise management authority to make significant decisions and certain strategic decisions or recommendations within own area. Negotiate with and influence stakeholders at a senior level both internally and externally. Act as principal contact point for key clients and counterparts in other functions/ businesses divisions. Mandated as a spokesperson for the function and business division. All Senior Leaders are expected to demonstrate a clear set of leadership behaviours to create an environment for colleagues to thrive and deliver to a consistently excellent standard. The four LEAD behaviours are: L - Listen and be authentic, E - Energise and inspire, A - Align across the enterprise, D - Develop others. All colleagues will be expected to demonstrate the Barclays Values of Respect, Integrity, Service, Excellence and Stewardship - our moral compass, helping us do what we believe is right. They will also be expected to demonstrate the Barclays Mindset - to Empower, Challenge and Drive - the operating manual for how we behave.
Mar 12, 2026
Full time
Own and shape the end to end technical architecture of the Payments Platform, ensuring scalability, resilience, and regulatory compliance. Act as design authority for complex and high risk payments initiatives across multiple squads and domains. Define and enforce engineering standards, reference architectures, and non functional requirements (availability, latency, throughput, security). Lead technical decisions across multi rail payments (e.g. real time, high value, cross border) and platform capabilities such as orchestration, clearing, and settlement. Embed security, controls, and operational resilience by design, partnering closely with Risk, Cyber, and Controls teams. Drive modernisation and platform evolution, reducing technical debt and enabling faster product and client onboarding. Provide technical leadership and mentorship to senior engineers, tech leads, and architects across Payments Technology. Influence delivery and outcomes without direct line management, acting as a trusted advisor to senior technology and business leaders. Ensure high standards of engineering quality, including test strategy, CI/CD, observability, and incident learnings. Purpose of the role To lead and manage engineering teams, providing technical guidance, mentorship, and support to ensure the delivery of high-quality software solutions, driving technical excellence, fostering a culture of innovation, and collaborating with cross-functional teams to align technical decisions with business objectives. Accountabilities Lead engineering teams effectively, fostering a collaborative and high-performance culture to achieve project goals and meet organizational objectives. Oversee timelines, team allocation, risk management and task prioritization to ensure the successful delivery of solutions within scope, time, and budget. Mentor and support team members' professional growth, conduct performance reviews, provide actionable feedback, and identify opportunities for improvement. Evaluation and enhancement of engineering processes, tools, and methodologies to increase efficiency, streamline workflows, and optimize team productivity. Collaboration with business partners, product managers, designers, and other stakeholders to translate business requirements into technical solutions and ensure a cohesive approach to product development. Enforcement of technology standards, facilitate peer reviews, and implement robust testing practices to ensure the delivery of high-quality solutions. Director Expectations To manage a business function, providing significant input to function wide strategic initiatives. Contribute to and influence policy and procedures for the function and plan, manage and consult on multiple complex and critical strategic projects, which may be business wide They manage the direction of a large team or sub-function, leading other people managers and embedding a performance culture aligned to the values of the business. Or for an individual contributor, they lead organisation wide projects and act as deep technical expert and thought leader, identifying new ways of working and collaborating cross functionally. They will train, guide and coach less experienced specialists and provide information affecting long term profits, organisational risks and strategic decisions Provide expert advice to senior functional management and committees to influence decisions made outside of own function, offering significant input to function wide strategic initiatives. Manage, coordinate and enable resourcing, budgeting and policy creation for a significant sub-function. Escalates breaches of policies / procedure appropriately. Foster and guide compliance, ensure regulations are observed that relevant processes in place to facilitate adherence. Focus on the external environment, regulators, or advocacy groups to both monitor and influence on behalf of Barclays, when appropriate. Demonstrate extensive knowledge of how the function integrates with the business division / Group to achieve the overall business objectives. Maintain broad and comprehensive knowledge of industry theories and practices within own discipline alongside up-to-date relevant sector / functional knowledge, and insight into external market developments / initiatives. Use interpretative thinking and advanced analytical skills to solve problems and design solutions in often complex/ sensitive situations. Exercise management authority to make significant decisions and certain strategic decisions or recommendations within own area. Negotiate with and influence stakeholders at a senior level both internally and externally. Act as principal contact point for key clients and counterparts in other functions/ businesses divisions. Mandated as a spokesperson for the function and business division. All Senior Leaders are expected to demonstrate a clear set of leadership behaviours to create an environment for colleagues to thrive and deliver to a consistently excellent standard. The four LEAD behaviours are: L - Listen and be authentic, E - Energise and inspire, A - Align across the enterprise, D - Develop others. All colleagues will be expected to demonstrate the Barclays Values of Respect, Integrity, Service, Excellence and Stewardship - our moral compass, helping us do what we believe is right. They will also be expected to demonstrate the Barclays Mindset - to Empower, Challenge and Drive - the operating manual for how we behave.
A global travel technology company in Greater London seeks a skilled software engineer to design and implement high-quality software services. The role involves leading complex features, mentoring team members, and integrating AI-driven solutions into products. Candidates should possess a relevant degree and significant professional experience in software engineering and system design. This position offers exciting travel perks and flexible work arrangements.
Mar 12, 2026
Full time
A global travel technology company in Greater London seeks a skilled software engineer to design and implement high-quality software services. The role involves leading complex features, mentoring team members, and integrating AI-driven solutions into products. Candidates should possess a relevant degree and significant professional experience in software engineering and system design. This position offers exciting travel perks and flexible work arrangements.
Sherwin-Williams is seeking a Fire Engineering & Estimation Engineerto join our FEET teamwithin the Passive Fire Protection business, supporting customers across the EMEAI region. This role focuses on providing estimation, specification, and technical supportfor passive fire protection solutions. Working as part of the FEET team, you will use Sherwin-Williams tools and expertise to help customers and internal stakeholders specify compliant, efficient, and value-driven fire protection systems. The position offers a strong foundation in engineering support, estimation, and customer collaboration, with exposure to commercial and project-facing activities. Responsibilities Key Responsibilities Provide engineering and estimation supportfor passive fire protection solutions in line with Sherwin-Williams standards and project requirements Carry out PFP coating thickness, quantity, and estimation calculationsusing FIRETEX Design Estimator (FDE)and supporting tools Assist in the preparation of technical submissions, specifications, and estimatesto support bids, tenders, and project delivery Interpret project documentation, including drawings and steel schedules, to generate accurate and consistent estimation outputs Work closely with senior FEET engineers and technical specialists to develop project-specific recommendations Support sales and commercial teams by providing technical input for proposals and early-stage project discussions Participate in customer meetings, presentations, and occasional site visits to support explanation of technical and estimation outputs Contribute to the continuous improvement of internal tools, processes, and calculation workflows Develop working knowledge of Sherwin-Williams product systems, test data, and relevant industry standards Assist with deployment of proprietary estimation software (FDE) and offer first line troubleshooting support Qualifications Degree in Engineering(Civil, Structural, Mechanical, Materials, or related discipline) Strong analytical skills with confidence in numerical and software-based calculation work Interest in passive fire protection, coatings, or engineering support roles Ability to work collaboratively across engineering, sales, and project teams UK driving license and access to a car for occasional customer or site visits Preferred Qualifications Experience in estimation, technical support, engineering consultancy, or construction-related roles Familiarity with calculation tools, estimation software, or BIM environments Exposure to passive fire protection, coatings, or specification-based engineering About Us At Sherwin-Williams, our purpose is to inspire and improve the world by coloring and protecting what matters. Our paints, coatings and innovative solutions make the places and spaces in our world brighter and stronger. Your skills, talent and passion make it possible to live this purpose, and for customers and our business to achieve great results. Sherwin-Williams is a place that takes its stability, growth and momentum and translates it to possibility for our people. Our people are behind the strength of our success, and we invest and support you in: Life with rewards, benefits and the flexibility to enhance your health and well-being Career with opportunities to learn, develop new skills and grow your contribution Connection with an inclusive team and commitment to our own and broader communities It's all here for you let's Create Your Possible Eligibility to Work You will need to provide proof of right to work. It is a condition of any offer of employment we make to you that you have the permission to work in the country for the role for which you are applying for. Equal Opportunity Employer An equal opportunity employer, all qualified applicants will receive consideration for employment and will not be discriminated against based on race, colour, religion or belief, gender, sexual orientation, gender identity, ethnic or national origin, disability, age pregnancy or maternity, marital or civil partner status, or any other protected characteristic prohibited by law. Please be aware, Sherwin-Williams recruiting team members will never request a candidate to provide a payment, ask for financial information, or sensitive personal information like national identification numbers, date of birth, or bank account numbers during the application process.
Mar 12, 2026
Full time
Sherwin-Williams is seeking a Fire Engineering & Estimation Engineerto join our FEET teamwithin the Passive Fire Protection business, supporting customers across the EMEAI region. This role focuses on providing estimation, specification, and technical supportfor passive fire protection solutions. Working as part of the FEET team, you will use Sherwin-Williams tools and expertise to help customers and internal stakeholders specify compliant, efficient, and value-driven fire protection systems. The position offers a strong foundation in engineering support, estimation, and customer collaboration, with exposure to commercial and project-facing activities. Responsibilities Key Responsibilities Provide engineering and estimation supportfor passive fire protection solutions in line with Sherwin-Williams standards and project requirements Carry out PFP coating thickness, quantity, and estimation calculationsusing FIRETEX Design Estimator (FDE)and supporting tools Assist in the preparation of technical submissions, specifications, and estimatesto support bids, tenders, and project delivery Interpret project documentation, including drawings and steel schedules, to generate accurate and consistent estimation outputs Work closely with senior FEET engineers and technical specialists to develop project-specific recommendations Support sales and commercial teams by providing technical input for proposals and early-stage project discussions Participate in customer meetings, presentations, and occasional site visits to support explanation of technical and estimation outputs Contribute to the continuous improvement of internal tools, processes, and calculation workflows Develop working knowledge of Sherwin-Williams product systems, test data, and relevant industry standards Assist with deployment of proprietary estimation software (FDE) and offer first line troubleshooting support Qualifications Degree in Engineering(Civil, Structural, Mechanical, Materials, or related discipline) Strong analytical skills with confidence in numerical and software-based calculation work Interest in passive fire protection, coatings, or engineering support roles Ability to work collaboratively across engineering, sales, and project teams UK driving license and access to a car for occasional customer or site visits Preferred Qualifications Experience in estimation, technical support, engineering consultancy, or construction-related roles Familiarity with calculation tools, estimation software, or BIM environments Exposure to passive fire protection, coatings, or specification-based engineering About Us At Sherwin-Williams, our purpose is to inspire and improve the world by coloring and protecting what matters. Our paints, coatings and innovative solutions make the places and spaces in our world brighter and stronger. Your skills, talent and passion make it possible to live this purpose, and for customers and our business to achieve great results. Sherwin-Williams is a place that takes its stability, growth and momentum and translates it to possibility for our people. Our people are behind the strength of our success, and we invest and support you in: Life with rewards, benefits and the flexibility to enhance your health and well-being Career with opportunities to learn, develop new skills and grow your contribution Connection with an inclusive team and commitment to our own and broader communities It's all here for you let's Create Your Possible Eligibility to Work You will need to provide proof of right to work. It is a condition of any offer of employment we make to you that you have the permission to work in the country for the role for which you are applying for. Equal Opportunity Employer An equal opportunity employer, all qualified applicants will receive consideration for employment and will not be discriminated against based on race, colour, religion or belief, gender, sexual orientation, gender identity, ethnic or national origin, disability, age pregnancy or maternity, marital or civil partner status, or any other protected characteristic prohibited by law. Please be aware, Sherwin-Williams recruiting team members will never request a candidate to provide a payment, ask for financial information, or sensitive personal information like national identification numbers, date of birth, or bank account numbers during the application process.
Senior FPGA Engineer Role Looking for an ambitious, proactive self-starter who identifies problems and takes ownership Xilinx RFSoC and/or Software Defined Radio experience required 5+ yrs experience Strong focus on VHDL development on AMD Xilinx platforms (Vivado) DSP expertise required Experience coding for on chip ARM cores Experience using external DDR Appreciation of wider system architecture, periph click apply for full job details
Mar 12, 2026
Full time
Senior FPGA Engineer Role Looking for an ambitious, proactive self-starter who identifies problems and takes ownership Xilinx RFSoC and/or Software Defined Radio experience required 5+ yrs experience Strong focus on VHDL development on AMD Xilinx platforms (Vivado) DSP expertise required Experience coding for on chip ARM cores Experience using external DDR Appreciation of wider system architecture, periph click apply for full job details
Select how often (in days) to receive an alert: Scientist IV Process Development (Downstream) Location: Oxford, GB Company: oxfordbiom Join Us in Changing Lives At OXB, our people are at the heart of everything we do. We're on a mission to enable life-changing therapies to reach patients around the world-and we're looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful. We're currently recruiting for a Scientist IV - Process Development (Downstream) to join our Downstream Process Development team. In this role, you will perform and report laboratory-based experiments or investigations in accordance with scientific or regulatory requirements in line with departmental objectives, playing a key part in advancing our mission and making a real difference. Your responsibilities in this role would be: Involvement in a range of activities including vector production at laboratory and pilot scales, process development and optimisation, technology transfer, and process characterization activities associated with the manufacture of new gene therapy vectors. Design and execute downstream vector purification and vector formulation activities for scale-up/scale-down of existing bioprocesses under the direction of the Team Leader or a senior scientist and in accordance with correct methodologies and procedures. Prepare written reports to a high standard and present data within the PD group. Liaise with other members of the PD group and assist with other development activities where appropriate. Ensure a high standard of record keeping and documentation of experiments and investigations. Writing of departmental risk assessments, SOPs, and other documentation where appropriate. We are looking for: Minimum BSc Degree programme level and/or relevant experience Sound understanding of downstream purification principles and processes. Competency in data capture, reporting and management systems. Familiarity with data analysis software packages such as Microsoft Excel, JMP, Design Expert , GraphPad Prism Experience with the operation of laboratory, pilot or production scale downstream purification processes. Pharmaceutical industry experience in biological research and development or equivalent experience gained elsewhere desirable, but not necessary The ability to explain clearly why an experiment is being conducted and how the experiments help the group meet their objectives. Awareness of regulatory requirements e.g. GMP, GLP, GCP and/or Validation and Quality Management systems. Fluency in written and spoken English. About Us: OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 30 years of experience in viral vectors; the driving force behind the majority of gene therapies. OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality assurance systems, analytical methods, and depth of regulatory expertise. Why Join Us? Wellbeing programmes that support your mental and physical health Career development opportunities to help you grow and thrive Supportive, inclusive, and collaborative culture State-of-the art labs and manufacturing facilities A company that lives its values: Responsible, Responsive, Resilient, Respect We want you to feel inspired every day. At OXB, we're future focused and growing fast. We succeed together-through passion, commitment, and teamwork.
Mar 12, 2026
Full time
Select how often (in days) to receive an alert: Scientist IV Process Development (Downstream) Location: Oxford, GB Company: oxfordbiom Join Us in Changing Lives At OXB, our people are at the heart of everything we do. We're on a mission to enable life-changing therapies to reach patients around the world-and we're looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful. We're currently recruiting for a Scientist IV - Process Development (Downstream) to join our Downstream Process Development team. In this role, you will perform and report laboratory-based experiments or investigations in accordance with scientific or regulatory requirements in line with departmental objectives, playing a key part in advancing our mission and making a real difference. Your responsibilities in this role would be: Involvement in a range of activities including vector production at laboratory and pilot scales, process development and optimisation, technology transfer, and process characterization activities associated with the manufacture of new gene therapy vectors. Design and execute downstream vector purification and vector formulation activities for scale-up/scale-down of existing bioprocesses under the direction of the Team Leader or a senior scientist and in accordance with correct methodologies and procedures. Prepare written reports to a high standard and present data within the PD group. Liaise with other members of the PD group and assist with other development activities where appropriate. Ensure a high standard of record keeping and documentation of experiments and investigations. Writing of departmental risk assessments, SOPs, and other documentation where appropriate. We are looking for: Minimum BSc Degree programme level and/or relevant experience Sound understanding of downstream purification principles and processes. Competency in data capture, reporting and management systems. Familiarity with data analysis software packages such as Microsoft Excel, JMP, Design Expert , GraphPad Prism Experience with the operation of laboratory, pilot or production scale downstream purification processes. Pharmaceutical industry experience in biological research and development or equivalent experience gained elsewhere desirable, but not necessary The ability to explain clearly why an experiment is being conducted and how the experiments help the group meet their objectives. Awareness of regulatory requirements e.g. GMP, GLP, GCP and/or Validation and Quality Management systems. Fluency in written and spoken English. About Us: OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 30 years of experience in viral vectors; the driving force behind the majority of gene therapies. OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality assurance systems, analytical methods, and depth of regulatory expertise. Why Join Us? Wellbeing programmes that support your mental and physical health Career development opportunities to help you grow and thrive Supportive, inclusive, and collaborative culture State-of-the art labs and manufacturing facilities A company that lives its values: Responsible, Responsive, Resilient, Respect We want you to feel inspired every day. At OXB, we're future focused and growing fast. We succeed together-through passion, commitment, and teamwork.
# About the Business Quilter plc is a leading wealth management business, helping to enable brighter financial futures for every generation. Quilter oversees £126.3 billion in customer investments (as of August 2025). It has an adviser and customer offering spanning financial advice, investment platforms, multi-asset investment solutions, and discretionary fund management. The business is comprised of two segments: Affluent and High Net Worth. Affluent encompasses the financial planning business, Quilter Financial Planning, the Quilter Investment Platform and Quilter Investors, the multi-asset investment solutions business. High Net Worth includes the discretionary fund management business, Quilter Cheviot, together with Quilter Cheviot Financial Planning - offering a highly personalised service to private clients, charities, trustees, and professional partners. Quilter Cheviot has presence throughout the UK, Ireland and Channel Islands. At Quilter we never stand still. Our foundations are rooted in our extraordinary expertise, which is trusted by hundreds of thousands of customers, but we have great ambitions to stay one step ahead and make an even greater difference to the people and communities we serve, including our colleagues. Our business is transforming, continually modernising, and becoming even more customer centric. So, if you want to be bold in the pursuit of your ambitions, bring new ideas, and challenge and evolve what we do, it's the perfect time to join us!# About the Role Level: 4Department: COOLocation: Southampton or LondonContract type: PermanentThe new role sits within AI Centre of Excellence department under Chief Operating Office (COO).The key accountabilities for the role are as follows: AI/ML Solution Delivery: Hands on end-to-end development and deployment of both traditional and GenAI-based machine learning models, including discovery analytics, experimental design, model development, benchmarking, enhancement and deployment. LLM & RAG Integration: Design and implement new Retrieval-Augmented Generation (RAG) pipelines and enhance existing frameworks, applying advanced techniques in data chunking/splitting, vectorization, knowledge graph representation (GraphRAG), and query retrieval and evaluation. Model Evaluation & Prompt Engineering: Design and execute experiments to benchmark and evaluate model performance using both classical metrics (precision, recall, F-score) and GenAI-specific techniques (LLM-as-a-Judge, ROUGE, BERTScore). Develop and refine prompts to optimise GenAI model reasoning, accuracy, and overall effectiveness. Cross-Functional Collaboration: Work closely with business partners, stakeholders, and technical teams (data engineering, platform engineering) to translate business requirements into impactful AI solutions. Research & Innovation: Stay abreast of emerging tools, techniques, and best practices in LLMs, RAG, GenAI, model development & evaluation techniques and proactively apply new knowledge to drive innovation.# About You Qualifications Advanced degree (MSc or PhD) in Machine Learning, Natural Language Processing, Artificial Intelligence, or a related field. Proven track record of delivering AI solutions from research to production in real-world applications. Knowledge Strong foundation in machine learning algorithms and deep learning concepts including Neural Networks and Transformer-based architectures. Knowledge in developing and deploying scalable models on Databricks, Azure, and AWS, leveraging tools such as FastAPI and Docker. Proficient in model tracing and observability for LLM in production and implementing evaluation frameworks for model quality and reliability. Strong understanding of software engineering best practices, including version control, testing, and CI/CD for production-ready AI systems. Domain expertise in financial services or other regulated industries is highly desirable. Experience Strong experience in AI/ML research and development, specializing in deep learning-based NLP, Information Retrieval, and Generative AI. Proven expertise in RAG/GraphRAG pipeline development and evaluation, including advanced retriever-reranker techniques. Experience in building knowledge bases and ontologies is highly desirable. Extensive experience in defining and implementing evaluation metrics for GenAI systems such as Recall, Precision, NDCG, LLM-as-a-Judge, BERTScore, BLEU score, and hallucination detection. Provide mentorship and technical guidance to junior AI Scientists Skills Strong proficiency in Python and experience with frameworks such as NumPy, Pandas, Scikit-learn, and modern Generative AI libraries (e.g., LangChain, LlamaIndex, Azure AI Foundry). Hands-on experience with PyTorch, and leading LLM libraries such as Hugging Face, LangChain, LangGraph, and LlamaIndex. Skilled in hypothesis formulation, defining evaluation metrics, conducting literature reviews, and building reproducible prototypes with critical outcome analysis. Rapid Experimentation Mindset: Comfortable with a fail-fast, learn-fast approach, iterating quickly to validate ideas and accelerate innovation. Exceptional problem-solving skills and a strong passion for innovation. Excellent communication and collaboration abilities, thriving in cross-functional environments. Inclusion & Diversity We value diversity and strive to promote inclusivity in all aspects of our culture. We believe in equal opportunities for all, ensuring that no applicant encounters less favourable treatment based on anything but their skills, qualifications, experience, and potential. We celebrate the unique contributions of a diverse workforce and create a respectful, nurturing environment where every colleague can thrive. Values Do the right thing: We act with integrity and are proudly committed to going above and beyond in service of our clients and the support we provide our communities. Always curious: We continuously seek new ideas and knowledge so we're one step ahead of our clients' needs. We look for inspiration everywhere and encourage experimentation, recognising that this is how we create brilliant solutions for brighter futures. Embrace challenge: We aim high to transform our potential into meaningful outcomes. With ambition as our driving force and a steadfast commitment to growth, we succeed for the good of every generation. Stronger together: Combining our diverse talents, we accomplish more collectively than we ever could do alone. We speak openly, actively listen, and support each other, and constructively challenge and embrace new ideas. We seek empowerment and demonstrate ownership and trust, with the confidence to make impactful decisions. Core Benefits Holiday: 182 hours (26 days) Quilter Incentive Scheme: All employees are eligible to participate in incentive scheme, to incentivise business performance and their contribution. Pension Scheme: A non-contributory company pension scheme that can be boosted through personal contributions. Private Medical Insurance: Single cover as standard with options to increase cover to include your partner or children. Life Assurance: 4x your salary. Income Protection: 75% of salary, less state benefits, payable after 26 weeks of absence. Healthcare Cash Plan: Jersey employees only In addition to our core benefits, we offer a range of flexible benefits to UK employees that you can choose from and pay for conveniently via a salary deduction. We create brighter financial futures for every generation.We do this by guiding our customers and their families through the complexity of planning for their financial future, responding to their rapidly evolving needs and giving them peace of mind. And, with all that's happening in the world today, our
Mar 12, 2026
Full time
# About the Business Quilter plc is a leading wealth management business, helping to enable brighter financial futures for every generation. Quilter oversees £126.3 billion in customer investments (as of August 2025). It has an adviser and customer offering spanning financial advice, investment platforms, multi-asset investment solutions, and discretionary fund management. The business is comprised of two segments: Affluent and High Net Worth. Affluent encompasses the financial planning business, Quilter Financial Planning, the Quilter Investment Platform and Quilter Investors, the multi-asset investment solutions business. High Net Worth includes the discretionary fund management business, Quilter Cheviot, together with Quilter Cheviot Financial Planning - offering a highly personalised service to private clients, charities, trustees, and professional partners. Quilter Cheviot has presence throughout the UK, Ireland and Channel Islands. At Quilter we never stand still. Our foundations are rooted in our extraordinary expertise, which is trusted by hundreds of thousands of customers, but we have great ambitions to stay one step ahead and make an even greater difference to the people and communities we serve, including our colleagues. Our business is transforming, continually modernising, and becoming even more customer centric. So, if you want to be bold in the pursuit of your ambitions, bring new ideas, and challenge and evolve what we do, it's the perfect time to join us!# About the Role Level: 4Department: COOLocation: Southampton or LondonContract type: PermanentThe new role sits within AI Centre of Excellence department under Chief Operating Office (COO).The key accountabilities for the role are as follows: AI/ML Solution Delivery: Hands on end-to-end development and deployment of both traditional and GenAI-based machine learning models, including discovery analytics, experimental design, model development, benchmarking, enhancement and deployment. LLM & RAG Integration: Design and implement new Retrieval-Augmented Generation (RAG) pipelines and enhance existing frameworks, applying advanced techniques in data chunking/splitting, vectorization, knowledge graph representation (GraphRAG), and query retrieval and evaluation. Model Evaluation & Prompt Engineering: Design and execute experiments to benchmark and evaluate model performance using both classical metrics (precision, recall, F-score) and GenAI-specific techniques (LLM-as-a-Judge, ROUGE, BERTScore). Develop and refine prompts to optimise GenAI model reasoning, accuracy, and overall effectiveness. Cross-Functional Collaboration: Work closely with business partners, stakeholders, and technical teams (data engineering, platform engineering) to translate business requirements into impactful AI solutions. Research & Innovation: Stay abreast of emerging tools, techniques, and best practices in LLMs, RAG, GenAI, model development & evaluation techniques and proactively apply new knowledge to drive innovation.# About You Qualifications Advanced degree (MSc or PhD) in Machine Learning, Natural Language Processing, Artificial Intelligence, or a related field. Proven track record of delivering AI solutions from research to production in real-world applications. Knowledge Strong foundation in machine learning algorithms and deep learning concepts including Neural Networks and Transformer-based architectures. Knowledge in developing and deploying scalable models on Databricks, Azure, and AWS, leveraging tools such as FastAPI and Docker. Proficient in model tracing and observability for LLM in production and implementing evaluation frameworks for model quality and reliability. Strong understanding of software engineering best practices, including version control, testing, and CI/CD for production-ready AI systems. Domain expertise in financial services or other regulated industries is highly desirable. Experience Strong experience in AI/ML research and development, specializing in deep learning-based NLP, Information Retrieval, and Generative AI. Proven expertise in RAG/GraphRAG pipeline development and evaluation, including advanced retriever-reranker techniques. Experience in building knowledge bases and ontologies is highly desirable. Extensive experience in defining and implementing evaluation metrics for GenAI systems such as Recall, Precision, NDCG, LLM-as-a-Judge, BERTScore, BLEU score, and hallucination detection. Provide mentorship and technical guidance to junior AI Scientists Skills Strong proficiency in Python and experience with frameworks such as NumPy, Pandas, Scikit-learn, and modern Generative AI libraries (e.g., LangChain, LlamaIndex, Azure AI Foundry). Hands-on experience with PyTorch, and leading LLM libraries such as Hugging Face, LangChain, LangGraph, and LlamaIndex. Skilled in hypothesis formulation, defining evaluation metrics, conducting literature reviews, and building reproducible prototypes with critical outcome analysis. Rapid Experimentation Mindset: Comfortable with a fail-fast, learn-fast approach, iterating quickly to validate ideas and accelerate innovation. Exceptional problem-solving skills and a strong passion for innovation. Excellent communication and collaboration abilities, thriving in cross-functional environments. Inclusion & Diversity We value diversity and strive to promote inclusivity in all aspects of our culture. We believe in equal opportunities for all, ensuring that no applicant encounters less favourable treatment based on anything but their skills, qualifications, experience, and potential. We celebrate the unique contributions of a diverse workforce and create a respectful, nurturing environment where every colleague can thrive. Values Do the right thing: We act with integrity and are proudly committed to going above and beyond in service of our clients and the support we provide our communities. Always curious: We continuously seek new ideas and knowledge so we're one step ahead of our clients' needs. We look for inspiration everywhere and encourage experimentation, recognising that this is how we create brilliant solutions for brighter futures. Embrace challenge: We aim high to transform our potential into meaningful outcomes. With ambition as our driving force and a steadfast commitment to growth, we succeed for the good of every generation. Stronger together: Combining our diverse talents, we accomplish more collectively than we ever could do alone. We speak openly, actively listen, and support each other, and constructively challenge and embrace new ideas. We seek empowerment and demonstrate ownership and trust, with the confidence to make impactful decisions. Core Benefits Holiday: 182 hours (26 days) Quilter Incentive Scheme: All employees are eligible to participate in incentive scheme, to incentivise business performance and their contribution. Pension Scheme: A non-contributory company pension scheme that can be boosted through personal contributions. Private Medical Insurance: Single cover as standard with options to increase cover to include your partner or children. Life Assurance: 4x your salary. Income Protection: 75% of salary, less state benefits, payable after 26 weeks of absence. Healthcare Cash Plan: Jersey employees only In addition to our core benefits, we offer a range of flexible benefits to UK employees that you can choose from and pay for conveniently via a salary deduction. We create brighter financial futures for every generation.We do this by guiding our customers and their families through the complexity of planning for their financial future, responding to their rapidly evolving needs and giving them peace of mind. And, with all that's happening in the world today, our
A global EdTech leader is seeking a Senior Software Engineer to join their Technology team in Sheffield. This role involves designing and delivering high-quality software used by educators, requiring expertise in mobile development, REST APIs, and mentoring other engineers. The position offers a hybrid working model and the chance to work in an agile environment that values continuous learning and technical excellence. Competitive salary available, up to £100,000.
Mar 12, 2026
Full time
A global EdTech leader is seeking a Senior Software Engineer to join their Technology team in Sheffield. This role involves designing and delivering high-quality software used by educators, requiring expertise in mobile development, REST APIs, and mentoring other engineers. The position offers a hybrid working model and the chance to work in an agile environment that values continuous learning and technical excellence. Competitive salary available, up to £100,000.
Over Head Line Design Engineer UK wide - (Hybrid) Permanent Competitive Salary + Car Allowance + Flexible Benefits Summary Freedom Professional Services are currently recruiting an Overhead Line Design Engineer to join our team. You will be based from either our Leeds, our Stowmarket or London offices, with options to work from Home. You will be required to Travel as and when required for client meetings, internal team meetings or site visits. The successful candidate will work with the team lead and be responsible for the design and delivery of overhead line (OHL) new build and refurbishment projects, providing technical expertise and guidance to the team. Some of the key deliverables in this role will include: Undertake the design and development of OHL projects, ensuring compliance with technical and safety standards, and client requirements. Responsible for all aspects of OHL design, including conductor sizing and modelling, insulation selection, lighting protection, line routing, PLS-CAD modelling, clearance checking and structure and foundation design and analysis using PLS-TOWER, or PLS-POLE. Production of technical documents, such as engineering reports, specifications, drawings, and calculations, ensuring accuracy and compliance with industry standards. Preparation of proposals for OHL design projects, including determination of design scope, allocating resource, costing program and deliverables. Provide technical support and guidance to the wider team, including tendering, mentoring, and training junior engineers Operate within the quality assurance manual of Freedom/NGB group or an established project management methodology which ensures the maintenance of equivalent standards. Attend site visits, inspections, and meetings as required. What we're looking for : Engineers that join our team will need to have diverse skill sets to bring technical, ethical, social and management competence to every job that we work on, for all of our professional clients and key stakeholders. Strong budgetary and project management skills are required at this level, accompanied by good commercial knowledge of design and construction contract forms such as NEC, and experience of working withing the contract conditions. The business proactively encourages chartership in engineering, and senior engineers are expected to be chartered or close to achieving chartership. You must have Qualifications and experience in: Degree in Electrical Engineering or related field. Experience in OHL design, including experience in the power transmission and distribution industry. Strong technical knowledge and understanding of OHL design principles and standards governing OHL design in the UK. A good level of technical experience in the production of designs, calculations, reports & drawings associated with new build and refurbishment OHL projects from 11kV - 400kV Experience in using design software such as PLS-CADD, PLS-POLE, and PLS-TOWER. Excellent communication skills, with the ability to communicate technical information to non-technical stakeholders. Ability to manage multiple projects and priorities, delivering to deadlines and budgets. Have a good understanding of CDM 2015 and the Electricity Safety, Quality and Continuity Regulations Sufficient knowledge of AutoCAD 3D to fulfil role. Knowledge of MicroStation CAD software (Desirable). CSCS Card Holder (Desirable) Full UK driving license. Benefits: We are always evolving our benefits to ensure we're attracting and retaining great people. Some of what you can expect includes: Competitive salary Car or Car allowance 25 days holiday plus Bank Holidays Pension with a leading provider and employer contribution Sick Pay Personal Wellbeing and Volunteer Days Private Medical Insurance Free 24/7 365 Employee Assistance Program to support mental health and well-being (including counselling sessions and legal advice) Flexible benefits to suit from Dental Insurance, Gym Memberships, Give As You Earn, Travel Insurance, Tax Free Bikes Personal development programme. Next Steps: As a business, we're on a journey to build on our culture where everyone is included, treated fairly and with respect. This starts with recruitment and how we bring people into the organisation. We'll do our best to outline the recruitment process to you ahead of time with plenty of notice. If you require any accommodations to participate in the application or interview process, please let us know and we will work with you to ensure your needs are met. About Us Freedom are part of the NG Bailey Group, one of the leading independent engineering and services businesses in the UK. Founded in 1921, with a turnover of £500m and 3000 employees, we are proud of our history of developing great people through our investment in training. Working across a variety of sectors within the building and infrastructure industry, our innovative, responsible and forward-thinking approach allows us to work on fantastic ground-breaking projects, providing solutions using the latest tools and technologies Progression is something we value and we will make sure that when you join us you have a clearly defined development path, supported by regular reviews, training and ongoing support to enable you to be the best you can be.
Mar 12, 2026
Full time
Over Head Line Design Engineer UK wide - (Hybrid) Permanent Competitive Salary + Car Allowance + Flexible Benefits Summary Freedom Professional Services are currently recruiting an Overhead Line Design Engineer to join our team. You will be based from either our Leeds, our Stowmarket or London offices, with options to work from Home. You will be required to Travel as and when required for client meetings, internal team meetings or site visits. The successful candidate will work with the team lead and be responsible for the design and delivery of overhead line (OHL) new build and refurbishment projects, providing technical expertise and guidance to the team. Some of the key deliverables in this role will include: Undertake the design and development of OHL projects, ensuring compliance with technical and safety standards, and client requirements. Responsible for all aspects of OHL design, including conductor sizing and modelling, insulation selection, lighting protection, line routing, PLS-CAD modelling, clearance checking and structure and foundation design and analysis using PLS-TOWER, or PLS-POLE. Production of technical documents, such as engineering reports, specifications, drawings, and calculations, ensuring accuracy and compliance with industry standards. Preparation of proposals for OHL design projects, including determination of design scope, allocating resource, costing program and deliverables. Provide technical support and guidance to the wider team, including tendering, mentoring, and training junior engineers Operate within the quality assurance manual of Freedom/NGB group or an established project management methodology which ensures the maintenance of equivalent standards. Attend site visits, inspections, and meetings as required. What we're looking for : Engineers that join our team will need to have diverse skill sets to bring technical, ethical, social and management competence to every job that we work on, for all of our professional clients and key stakeholders. Strong budgetary and project management skills are required at this level, accompanied by good commercial knowledge of design and construction contract forms such as NEC, and experience of working withing the contract conditions. The business proactively encourages chartership in engineering, and senior engineers are expected to be chartered or close to achieving chartership. You must have Qualifications and experience in: Degree in Electrical Engineering or related field. Experience in OHL design, including experience in the power transmission and distribution industry. Strong technical knowledge and understanding of OHL design principles and standards governing OHL design in the UK. A good level of technical experience in the production of designs, calculations, reports & drawings associated with new build and refurbishment OHL projects from 11kV - 400kV Experience in using design software such as PLS-CADD, PLS-POLE, and PLS-TOWER. Excellent communication skills, with the ability to communicate technical information to non-technical stakeholders. Ability to manage multiple projects and priorities, delivering to deadlines and budgets. Have a good understanding of CDM 2015 and the Electricity Safety, Quality and Continuity Regulations Sufficient knowledge of AutoCAD 3D to fulfil role. Knowledge of MicroStation CAD software (Desirable). CSCS Card Holder (Desirable) Full UK driving license. Benefits: We are always evolving our benefits to ensure we're attracting and retaining great people. Some of what you can expect includes: Competitive salary Car or Car allowance 25 days holiday plus Bank Holidays Pension with a leading provider and employer contribution Sick Pay Personal Wellbeing and Volunteer Days Private Medical Insurance Free 24/7 365 Employee Assistance Program to support mental health and well-being (including counselling sessions and legal advice) Flexible benefits to suit from Dental Insurance, Gym Memberships, Give As You Earn, Travel Insurance, Tax Free Bikes Personal development programme. Next Steps: As a business, we're on a journey to build on our culture where everyone is included, treated fairly and with respect. This starts with recruitment and how we bring people into the organisation. We'll do our best to outline the recruitment process to you ahead of time with plenty of notice. If you require any accommodations to participate in the application or interview process, please let us know and we will work with you to ensure your needs are met. About Us Freedom are part of the NG Bailey Group, one of the leading independent engineering and services businesses in the UK. Founded in 1921, with a turnover of £500m and 3000 employees, we are proud of our history of developing great people through our investment in training. Working across a variety of sectors within the building and infrastructure industry, our innovative, responsible and forward-thinking approach allows us to work on fantastic ground-breaking projects, providing solutions using the latest tools and technologies Progression is something we value and we will make sure that when you join us you have a clearly defined development path, supported by regular reviews, training and ongoing support to enable you to be the best you can be.
Ctrl Alt is designing and operating the on-chain infrastructure powering digital capital markets globally. We bring together a unique blend of expertise in financial markets and cutting edge in house technology to deliver tailored, compliant solutions in the alternative assets space. Since launching in 2022, we've tokenized over $1bn in assets across real estate, private credit, funds, litigation finance and more. We're building a high performance, people first culture where ambitious individuals can thrive. We move fast, think big and hold ourselves to a high bar, while keeping things collaborative, open and genuinely fun. At Ctrl Alt ideas win on merit, teams work closely with leadership, and everyone has a voice in shaping what we build next. We believe that hard work should come with real reward. You won't just join a company - you'll help build one. Last year alone, we grew from 17 to 50 people, and this year we're going faster and further. That means real responsibility, meaningful impact, and the opportunity to grow alongside a company that's redefining the future of finance through the tokenization of alternative assets. If you're excited by scale up energy, ownership, and the chance to help shape both a business and a culture, Ctrl Alt is where you can do the most rewarding work of your career. AS SEEN IN What's Involved Note: We do not offer sponsorship for this role Design, build and maintain high performing, flexible and scalable solutions Build upon our existing app to create products and features that help our users understand their investments, manage their portfolios and participate in voting rights of their assets Build APIs for our partners to access and place orders our platform Take a loosely defined problem through to a valid, technically sound, thoroughly documented, tested, and implemented software solution Collaborate with team members and other engineers across the company Advocate best coding practices to raise the bar for you, your team and the company Mentor engineers on your team supporting them in their growth Requirements Must Haves 5+ years experience as a Software Engineer Comfortable writing backend code to be performant and efficient Experience building RESTful application interfaces and designing APIs Experience working as a part of a multi-person development team that utilizes automated testing, CI/CD pipelines and peer reviews in an Agile Environment Nice to Haves Strong engineering principles Excellent communication skills - written and verbal Experience in React and React Native Join a scaling fintech building the next generation of investment banking. You'll work at the intersection of capital markets and cutting edge blockchain technology, helping drive and shape the future of financial infrastructure. What it's like working at Ctrl Alt Build and own the future of finance - Take real responsibility in shaping digital capital markets, with the autonomy to lead decisions and drive impact. Solve meaningful problems with exceptional people - Tackle complex challenges at the intersection of finance and technology alongside leaders with experience from Morgan Stanley, Credit Suisse, UBS, and Revolut. Grow fast in a high-performance environment - Stretch beyond your comfort zone through close collaboration, rapid feedback, and continuous learning. Innovate and make your mark - Bring bold ideas to life and influence our platform, products, and how we operate from day one. Grow at speed - Stretch beyond your comfort zone with increased responsibility, fast feedback, and an environment designed for continuous improvement. How we support you Competitive salaries with regular reviews that reflect your impact, performance, and progression. Generous stock options so you directly share in the company's growth and long term success. Premium private healthcare to support your physical wellbeing. 26 days of annual leave, plus your birthday off, and regional bank holidays - with flexible leave so you can take time off when you need it. An enhanced parental leave policy to support you and your family at every stage. A MacBook, screens, and any additional equipment you need to perform at a high level. Access to salary sacrifice schemes covering childcare, groceries, EV cars, tech, pensions, bikes, and subscriptions. Modern, centrally located offices in London, Belfast, Dundalk, and Dubai - designed for collaboration and focus. An annual learning and personal development budget for training, exams, certifications, and qualifications - whatever helps you move forward. How to Apply Simply hit apply below, where you will be redirected to a form to fill out all relevant details. You will be asked to upload a CV and Cover Letter. Interview Process:
Mar 12, 2026
Full time
Ctrl Alt is designing and operating the on-chain infrastructure powering digital capital markets globally. We bring together a unique blend of expertise in financial markets and cutting edge in house technology to deliver tailored, compliant solutions in the alternative assets space. Since launching in 2022, we've tokenized over $1bn in assets across real estate, private credit, funds, litigation finance and more. We're building a high performance, people first culture where ambitious individuals can thrive. We move fast, think big and hold ourselves to a high bar, while keeping things collaborative, open and genuinely fun. At Ctrl Alt ideas win on merit, teams work closely with leadership, and everyone has a voice in shaping what we build next. We believe that hard work should come with real reward. You won't just join a company - you'll help build one. Last year alone, we grew from 17 to 50 people, and this year we're going faster and further. That means real responsibility, meaningful impact, and the opportunity to grow alongside a company that's redefining the future of finance through the tokenization of alternative assets. If you're excited by scale up energy, ownership, and the chance to help shape both a business and a culture, Ctrl Alt is where you can do the most rewarding work of your career. AS SEEN IN What's Involved Note: We do not offer sponsorship for this role Design, build and maintain high performing, flexible and scalable solutions Build upon our existing app to create products and features that help our users understand their investments, manage their portfolios and participate in voting rights of their assets Build APIs for our partners to access and place orders our platform Take a loosely defined problem through to a valid, technically sound, thoroughly documented, tested, and implemented software solution Collaborate with team members and other engineers across the company Advocate best coding practices to raise the bar for you, your team and the company Mentor engineers on your team supporting them in their growth Requirements Must Haves 5+ years experience as a Software Engineer Comfortable writing backend code to be performant and efficient Experience building RESTful application interfaces and designing APIs Experience working as a part of a multi-person development team that utilizes automated testing, CI/CD pipelines and peer reviews in an Agile Environment Nice to Haves Strong engineering principles Excellent communication skills - written and verbal Experience in React and React Native Join a scaling fintech building the next generation of investment banking. You'll work at the intersection of capital markets and cutting edge blockchain technology, helping drive and shape the future of financial infrastructure. What it's like working at Ctrl Alt Build and own the future of finance - Take real responsibility in shaping digital capital markets, with the autonomy to lead decisions and drive impact. Solve meaningful problems with exceptional people - Tackle complex challenges at the intersection of finance and technology alongside leaders with experience from Morgan Stanley, Credit Suisse, UBS, and Revolut. Grow fast in a high-performance environment - Stretch beyond your comfort zone through close collaboration, rapid feedback, and continuous learning. Innovate and make your mark - Bring bold ideas to life and influence our platform, products, and how we operate from day one. Grow at speed - Stretch beyond your comfort zone with increased responsibility, fast feedback, and an environment designed for continuous improvement. How we support you Competitive salaries with regular reviews that reflect your impact, performance, and progression. Generous stock options so you directly share in the company's growth and long term success. Premium private healthcare to support your physical wellbeing. 26 days of annual leave, plus your birthday off, and regional bank holidays - with flexible leave so you can take time off when you need it. An enhanced parental leave policy to support you and your family at every stage. A MacBook, screens, and any additional equipment you need to perform at a high level. Access to salary sacrifice schemes covering childcare, groceries, EV cars, tech, pensions, bikes, and subscriptions. Modern, centrally located offices in London, Belfast, Dundalk, and Dubai - designed for collaboration and focus. An annual learning and personal development budget for training, exams, certifications, and qualifications - whatever helps you move forward. How to Apply Simply hit apply below, where you will be redirected to a form to fill out all relevant details. You will be asked to upload a CV and Cover Letter. Interview Process:
On-site Audio-Visual Engineer Behaving as an ambassador for the AV Department at all times, including the technical setup, operation, and repair of equipment used to enhance collaborative meetings and live events. Knowledge & Key Skills - Onsite Work: 90% The on-site AV Engineer will prepare meeting rooms for presentations, Video and Audio conferencing, and collaboration Supporting a wide variety of AV software and hardware Comprehensive ability to troubleshoot a wide range of technology incidents and problems Using Service Desk software to effectively manage all support and service requests Taking complete ownership of and resolving all notified support and service issues, promptly, courteously, and professionally to agreed service levels (SLAs) Keeping end-users fully informed during and at resolution, leaving them assured that they are receiving the best attention Maintaining training and support function documentation Effectively communicating with internal customers with respect to support issues Maintaining an accurate inventory of all AV hardware, firmware, software, and configurations Contributing to the specification and procurement of new hardware and software Monitoring and optimising AV system performance Assist in office relocations Leaving the support function in such a state that it could easily be picked up by colleagues during an absence. Admin 10% Follow appropriate departmental and company procedures and policies (i.e., change control, problem and incident management) Monitor performance through the scorecard Monthly meetings with on-site primary contact Reporting ticket management Essential: Previous AV support experience in a concierge service Skilled AV Engineer possessing good interpersonal skills, and should be comfortable with Senior Management Must be smart and confident in their appearance. Should have proven abilities within the AV industry and/or corporate environment for over 5 years Excellent communication and customer service skills Enthusiastic and organised Ability to work under pressure Good knowledge OF Crestron, AMX, and RTI Knowledge of Lutron lighting control, Polycom, and MS Teams A firm understanding of networking protocols, RS232, and RS485 Good understanding of VOIP telephony and SIP Good understanding of video collaboration and audio conferencing Desirable: Avixa CTS Crestron P101 Extron School of AV Cisco CCNA
Mar 12, 2026
Full time
On-site Audio-Visual Engineer Behaving as an ambassador for the AV Department at all times, including the technical setup, operation, and repair of equipment used to enhance collaborative meetings and live events. Knowledge & Key Skills - Onsite Work: 90% The on-site AV Engineer will prepare meeting rooms for presentations, Video and Audio conferencing, and collaboration Supporting a wide variety of AV software and hardware Comprehensive ability to troubleshoot a wide range of technology incidents and problems Using Service Desk software to effectively manage all support and service requests Taking complete ownership of and resolving all notified support and service issues, promptly, courteously, and professionally to agreed service levels (SLAs) Keeping end-users fully informed during and at resolution, leaving them assured that they are receiving the best attention Maintaining training and support function documentation Effectively communicating with internal customers with respect to support issues Maintaining an accurate inventory of all AV hardware, firmware, software, and configurations Contributing to the specification and procurement of new hardware and software Monitoring and optimising AV system performance Assist in office relocations Leaving the support function in such a state that it could easily be picked up by colleagues during an absence. Admin 10% Follow appropriate departmental and company procedures and policies (i.e., change control, problem and incident management) Monitor performance through the scorecard Monthly meetings with on-site primary contact Reporting ticket management Essential: Previous AV support experience in a concierge service Skilled AV Engineer possessing good interpersonal skills, and should be comfortable with Senior Management Must be smart and confident in their appearance. Should have proven abilities within the AV industry and/or corporate environment for over 5 years Excellent communication and customer service skills Enthusiastic and organised Ability to work under pressure Good knowledge OF Crestron, AMX, and RTI Knowledge of Lutron lighting control, Polycom, and MS Teams A firm understanding of networking protocols, RS232, and RS485 Good understanding of VOIP telephony and SIP Good understanding of video collaboration and audio conferencing Desirable: Avixa CTS Crestron P101 Extron School of AV Cisco CCNA
Salient Bio is a cutting-edge clinical diagnostics laboratory based in London, specialising in clinical-grade microbiome testing. It operates a full-stack microbiome platform-covering everything from sample kit assembly and wet-lab processing to advanced data analysis and machine-learning-driven interpretation. By maintaining end-to-end control over workflows, Salient Bio delivers highly precise and reliable microbiome insights that support disease diagnosis and wellness testing. Its interdisciplinary team includes scientists and software engineers working collaboratively to transform microbiome research into real-world healthcare impact. The Role Salient Bio is seeking an experienced and motivated Senior Scientist (Microbiome) to play a central role in advancing its diagnostic and wellness testing portfolio. This is a senior scientific position with opportunities for leadership, innovation, and professional growth within a fast-growing biotech company. The Senior Scientist in this role will contribute to the development of new in-vitro diagnostic microbiometests, refine laboratory workflows, collaborate closely with bioinformatics teams, and support grant-funded research initiatives and clinical studies. Key Responsibilities Lead and contribute to grant applications supporting microbiome research, pilot studies, and clinical trials Design and improve diagnostic and wellness microbiome testing products Conduct critical literature reviews and translate findings into applied research strategies Collaborate with bioinformatics teams to enhance microbiome data analysis and client reports Design and deliver bespoke microbiome studies for external partners and clients Develop, validate, and optimise laboratory protocols and workflows Transition R&D protocols into routine diagnostic workflows by writing SOPs and training staff Support NGS workflow optimisation and scalability alongside the NGS Lab Manager Participate in sample processing when required (from receipt to sequencing or qPCR) 6+ years of microbiome and microbiology experience (PhD, postdoctoral, or equivalent industry background) Proven experience contributing to successful grant applications Strong wet-lab expertise in molecular biology (DNA/RNA extraction, PCR, QC) Understanding of standard quality controls in NGS workflows Excellent scientific communication and data interpretation skills Strong organisational and project-management abilities Experience mentoring or training junior team members High attention to detail and documentation (UKAS-accredited environment) How to Apply Interested candidates should send their CV to:
Mar 12, 2026
Full time
Salient Bio is a cutting-edge clinical diagnostics laboratory based in London, specialising in clinical-grade microbiome testing. It operates a full-stack microbiome platform-covering everything from sample kit assembly and wet-lab processing to advanced data analysis and machine-learning-driven interpretation. By maintaining end-to-end control over workflows, Salient Bio delivers highly precise and reliable microbiome insights that support disease diagnosis and wellness testing. Its interdisciplinary team includes scientists and software engineers working collaboratively to transform microbiome research into real-world healthcare impact. The Role Salient Bio is seeking an experienced and motivated Senior Scientist (Microbiome) to play a central role in advancing its diagnostic and wellness testing portfolio. This is a senior scientific position with opportunities for leadership, innovation, and professional growth within a fast-growing biotech company. The Senior Scientist in this role will contribute to the development of new in-vitro diagnostic microbiometests, refine laboratory workflows, collaborate closely with bioinformatics teams, and support grant-funded research initiatives and clinical studies. Key Responsibilities Lead and contribute to grant applications supporting microbiome research, pilot studies, and clinical trials Design and improve diagnostic and wellness microbiome testing products Conduct critical literature reviews and translate findings into applied research strategies Collaborate with bioinformatics teams to enhance microbiome data analysis and client reports Design and deliver bespoke microbiome studies for external partners and clients Develop, validate, and optimise laboratory protocols and workflows Transition R&D protocols into routine diagnostic workflows by writing SOPs and training staff Support NGS workflow optimisation and scalability alongside the NGS Lab Manager Participate in sample processing when required (from receipt to sequencing or qPCR) 6+ years of microbiome and microbiology experience (PhD, postdoctoral, or equivalent industry background) Proven experience contributing to successful grant applications Strong wet-lab expertise in molecular biology (DNA/RNA extraction, PCR, QC) Understanding of standard quality controls in NGS workflows Excellent scientific communication and data interpretation skills Strong organisational and project-management abilities Experience mentoring or training junior team members High attention to detail and documentation (UKAS-accredited environment) How to Apply Interested candidates should send their CV to:
Technically, you should be strong AWS experts with experience across software architecture and network infrastructure . The environment involves technologies supporting process orchestration, data platforms, calculation engines, and data distribution platforms , within a large-scale nationwide infrastructure where cyber compliance is a key consideration . We are looking for hands-on architects who can actively contribute to solution design in collaboration with engineering leadership, including senior stakeholders at the CIO/CTO leadership level. These architect will also play a role in navigating governance frameworks and internal approval structures, helping secure the required permits to build and permits to operate for the proposed solutions. AWS Cloud Infrastructure & APIs Design and implement scalable, secure AWS architectures for market data and pricing platforms Architect and govern API layers (REST / event-driven) for internal and external consumers Ensure high availability, performance and resilience across critical financial systems Solutioning & DevOps Lead solution design across multiple delivery teams Define and embed DevOps and Infrastructure-as-Code practices (Terraform, CloudFormation, CDK) Support CI/CD pipelines and automated deployment strategies Partner with engineering teams to ensure solutions are buildable and operable Required Skills & Experience Core Technical Strong AWS architecture experience (VPC, IAM, EC2, S3, RDS, DynamoDB, Lambda, EKS, Glue, Kinesis or equivalents) API and integration design experience Strong background in DevOps and automation Solid understanding of data migration and data platform design Experience designing scalable data processing pipelines Strong data modelling fundamentals
Mar 12, 2026
Full time
Technically, you should be strong AWS experts with experience across software architecture and network infrastructure . The environment involves technologies supporting process orchestration, data platforms, calculation engines, and data distribution platforms , within a large-scale nationwide infrastructure where cyber compliance is a key consideration . We are looking for hands-on architects who can actively contribute to solution design in collaboration with engineering leadership, including senior stakeholders at the CIO/CTO leadership level. These architect will also play a role in navigating governance frameworks and internal approval structures, helping secure the required permits to build and permits to operate for the proposed solutions. AWS Cloud Infrastructure & APIs Design and implement scalable, secure AWS architectures for market data and pricing platforms Architect and govern API layers (REST / event-driven) for internal and external consumers Ensure high availability, performance and resilience across critical financial systems Solutioning & DevOps Lead solution design across multiple delivery teams Define and embed DevOps and Infrastructure-as-Code practices (Terraform, CloudFormation, CDK) Support CI/CD pipelines and automated deployment strategies Partner with engineering teams to ensure solutions are buildable and operable Required Skills & Experience Core Technical Strong AWS architecture experience (VPC, IAM, EC2, S3, RDS, DynamoDB, Lambda, EKS, Glue, Kinesis or equivalents) API and integration design experience Strong background in DevOps and automation Solid understanding of data migration and data platform design Experience designing scalable data processing pipelines Strong data modelling fundamentals
Job Title: Electrical Contract Manager Location: Cambridge (North), Cambridgeshire Salary: Depending on experience Benefits: Company car or car allowance, 25 days holiday + Bank Holidays, pension A reputable regional M&E Contractor are looking for an Electrical Contract Manager to join their established team. The company provides M&E services to a wide range of clients across a variety of sectors including Commercial, Education, Life Sciences, Industrial, Healthcare, Leisure and Residential. You will be responsible to lead and oversee the projects from pre-construction to completion ensuring the projects are completed on time, within budget, and to the highest quality standards. As the Electrical Contract Manager, you will have the following responsibilities: Oversee and lead the preparation and execution of the electrical element of large-scale commercial projects running simultaneously. Co-ordinate with project management teams, sub-contractors and suppliers to ensure smooth project execution. Provide leadership to Electrical Project Managers and Electrical Engineers. Monitor project progress and performance, addressing any issues that arise. Identify and mitigate project risks, ensuring solutions are implemented effectively. Manage budgets, schedules, and resources effectively. Maintain close working relationships with clients, stakeholders, sub-contractors and internal teams to manage progress, challenges, and resolutions. Successful applicants will have the following experience: Previous experience within a leadership role and managing Electrical Project Managers. Proven track record of successfully managing complex electrical projects. Overall knowledge and understanding of a wide variety of electrical systems, construction practices and industry standards. Effective planning and project management skills, including planning, scheduling and resource allocation. Strong understanding of budgeting, cost control and financial analysis. Excellent leadership, communication, and problem-solving skills to achieve project goals. The ability to work under pressure to meet set deadlines. You will have SMSTS, CSCS skills card and relevant electrical industry qualification. Proficient in Microsoft Office and project management software. Please contact Adam Brown on (phone number removed) / (phone number removed) for more information about this role or if you are interested in an opportunity within the Building Services sector (Electrical Contract Manager, Electrical Project Manager, Senior Electrical Project Manager, M&E Contract Manager, MEP Contract Manager)
Mar 12, 2026
Full time
Job Title: Electrical Contract Manager Location: Cambridge (North), Cambridgeshire Salary: Depending on experience Benefits: Company car or car allowance, 25 days holiday + Bank Holidays, pension A reputable regional M&E Contractor are looking for an Electrical Contract Manager to join their established team. The company provides M&E services to a wide range of clients across a variety of sectors including Commercial, Education, Life Sciences, Industrial, Healthcare, Leisure and Residential. You will be responsible to lead and oversee the projects from pre-construction to completion ensuring the projects are completed on time, within budget, and to the highest quality standards. As the Electrical Contract Manager, you will have the following responsibilities: Oversee and lead the preparation and execution of the electrical element of large-scale commercial projects running simultaneously. Co-ordinate with project management teams, sub-contractors and suppliers to ensure smooth project execution. Provide leadership to Electrical Project Managers and Electrical Engineers. Monitor project progress and performance, addressing any issues that arise. Identify and mitigate project risks, ensuring solutions are implemented effectively. Manage budgets, schedules, and resources effectively. Maintain close working relationships with clients, stakeholders, sub-contractors and internal teams to manage progress, challenges, and resolutions. Successful applicants will have the following experience: Previous experience within a leadership role and managing Electrical Project Managers. Proven track record of successfully managing complex electrical projects. Overall knowledge and understanding of a wide variety of electrical systems, construction practices and industry standards. Effective planning and project management skills, including planning, scheduling and resource allocation. Strong understanding of budgeting, cost control and financial analysis. Excellent leadership, communication, and problem-solving skills to achieve project goals. The ability to work under pressure to meet set deadlines. You will have SMSTS, CSCS skills card and relevant electrical industry qualification. Proficient in Microsoft Office and project management software. Please contact Adam Brown on (phone number removed) / (phone number removed) for more information about this role or if you are interested in an opportunity within the Building Services sector (Electrical Contract Manager, Electrical Project Manager, Senior Electrical Project Manager, M&E Contract Manager, MEP Contract Manager)
About Sava All the health information we need is within us. Just below the skin. SAVA is redefining the way people interact with their health by developing the most advanced biosensing technology science has to offer, capable of accessing bodily information in a painless, real-time and affordable way. The Role We are seeking an exceptional Senior Scientist to join our New Analyte Team within the Biosensing and In Vivo Performance Department. This role will be directly reporting into the New Analyte Team Lead. This role is critical to future sensor development, focusing on the development of novel enzymatic and non-enzymatic based sensing technologies which will help shape and define the future of this company. This is a highly practical hands on role which will require a meticulous and tenacious approach to work. We're looking for someone willing to own end to end sensor development cycles from upstream process development to downstream performance testing and characterisation. The ideal candidate will have demonstrated excellence in process science, chemistry, or biotechnology; solid understanding of designing and executing experiments to capture quantitative data, with the ability to translate findings into actionable product and performance improvements. A track record of taking initiative-identifying problems, proposing solutions, and seeing them through to completion without waiting to be directed. The determination and curiosity to push through setbacks and iterate toward breakthroughs. What You'll Do Work within the New Analyte Team to develop and characterise novel sensing blend formulations using defined Process tools and QC instrumentation. Collaborate with the Synthesis, Process, and Biomaterials teams to learn, optimise and implement material and process changes for improved sensor performance. Build upon and develop existing protocols to further the understanding of various aspects of materials and processes used in sensor manufacturing and performance characterisation. Develop explorative trials, including DoE trials, that investigate material and process parameters to optimise sensor performance. Carry out performance testing of new sensing formulations. Generate, analyse and report data to the team and wider company, verbally and in writing. Research and implement novel test methods and experimental procedures support characterisation. Liaise with internal and external stakeholders to coordinate projects, manage deadlines and requirements in parallel to advancing device development. Support internal and external collaborations with vendors and research groups. What We're Looking For BSc degree or above, and at least 2-4 years lab experience in a relevant discipline (e.g., chemistry, process science, materials science). Experience in a lab/industry working with process development and characterisation. Hands on experience in a biotechnology, process chemistry or synthetic chemistry laboratory setting, either through university research projects, industry positions, and/or internships. A multidisciplinary background is highly advantageous. The candidate will be expected to work cross functionally with teams including Biosensing, Synthetic Chemistry, Manufacturing, Data and Engineering, which may include: process characterisation, new material investigation, medical device manufacture, sterilisation, in vitro testing, enzyme stability and activity, microscopy (Keyence experience), operation of precision dispensing systems. Bonus Points For Experience working in a start up environment. Working knowledge of electrochemical testing using Palmsense hardware/software. Working knowledge of Precision Dispensing equipment. Why Sava? This is a high ownership, high responsibility role in a company that's building something complex, meaningful, and fast. The expectations are high, the learning curve is steep, and the work is often messy - but the impact is real. We don't have room for egos or passengers. What we do have is a team of thoughtful, driven, and mission aligned people who are committed to building something better-and doing it with urgency and integrity.
Mar 11, 2026
Full time
About Sava All the health information we need is within us. Just below the skin. SAVA is redefining the way people interact with their health by developing the most advanced biosensing technology science has to offer, capable of accessing bodily information in a painless, real-time and affordable way. The Role We are seeking an exceptional Senior Scientist to join our New Analyte Team within the Biosensing and In Vivo Performance Department. This role will be directly reporting into the New Analyte Team Lead. This role is critical to future sensor development, focusing on the development of novel enzymatic and non-enzymatic based sensing technologies which will help shape and define the future of this company. This is a highly practical hands on role which will require a meticulous and tenacious approach to work. We're looking for someone willing to own end to end sensor development cycles from upstream process development to downstream performance testing and characterisation. The ideal candidate will have demonstrated excellence in process science, chemistry, or biotechnology; solid understanding of designing and executing experiments to capture quantitative data, with the ability to translate findings into actionable product and performance improvements. A track record of taking initiative-identifying problems, proposing solutions, and seeing them through to completion without waiting to be directed. The determination and curiosity to push through setbacks and iterate toward breakthroughs. What You'll Do Work within the New Analyte Team to develop and characterise novel sensing blend formulations using defined Process tools and QC instrumentation. Collaborate with the Synthesis, Process, and Biomaterials teams to learn, optimise and implement material and process changes for improved sensor performance. Build upon and develop existing protocols to further the understanding of various aspects of materials and processes used in sensor manufacturing and performance characterisation. Develop explorative trials, including DoE trials, that investigate material and process parameters to optimise sensor performance. Carry out performance testing of new sensing formulations. Generate, analyse and report data to the team and wider company, verbally and in writing. Research and implement novel test methods and experimental procedures support characterisation. Liaise with internal and external stakeholders to coordinate projects, manage deadlines and requirements in parallel to advancing device development. Support internal and external collaborations with vendors and research groups. What We're Looking For BSc degree or above, and at least 2-4 years lab experience in a relevant discipline (e.g., chemistry, process science, materials science). Experience in a lab/industry working with process development and characterisation. Hands on experience in a biotechnology, process chemistry or synthetic chemistry laboratory setting, either through university research projects, industry positions, and/or internships. A multidisciplinary background is highly advantageous. The candidate will be expected to work cross functionally with teams including Biosensing, Synthetic Chemistry, Manufacturing, Data and Engineering, which may include: process characterisation, new material investigation, medical device manufacture, sterilisation, in vitro testing, enzyme stability and activity, microscopy (Keyence experience), operation of precision dispensing systems. Bonus Points For Experience working in a start up environment. Working knowledge of electrochemical testing using Palmsense hardware/software. Working knowledge of Precision Dispensing equipment. Why Sava? This is a high ownership, high responsibility role in a company that's building something complex, meaningful, and fast. The expectations are high, the learning curve is steep, and the work is often messy - but the impact is real. We don't have room for egos or passengers. What we do have is a team of thoughtful, driven, and mission aligned people who are committed to building something better-and doing it with urgency and integrity.
Graduate Software Engineer (2026 Graduate) Cheltenham £28,000 + Training + Progression + Pension An excellent opportunity awaits a 2026 graduate pursuing a career in software engineering. This role offers exposure to varied projects, strong mentorship, and the chance to grow within an established software business known for developing graduate talent.This company is a small but well-established software house, highly regarded in the engineering sector for delivering bespoke in-house software solutions for complex electronics projects.In this role, you will join a tight-knit, experienced development team. After initial training to learn the company's products and solutions, you will begin contributing to hands-on support and development tasks, building new features, fixing bugs, and assisting on projects that deliver robust and reliable software to a global customer base. As a graduate engineer, you will receive strong mentorship from senior engineers as you transition into industry. This role is based in Cheltenham, five days per week, to provide consistent support and development.The ideal candidate will be graduating in 2026 with a background in computer science, electronics, or a similar field, and will be keen to pursue a career in software engineering. Candidates should have a solid understanding and practical experience with object?oriented programming, particularly C++. An interest in electronics, geometry, complex algorithms, or graphics will be beneficial.This is a fantastic opportunity for a graduate to gain broad hands-on experience, develop as a software engineer, and build a long-term career within a respected engineering business. The Role: Software development, maintaining and creating new features Exposure to real commercial projects, bug fixing, and team collaboration Extensive training, mentorship, and clear progression path Office-based in Cheltenham The Person: 2026 Graduate, looking to pursue a career in software engineering Hands on expereince with C++, with a willingness to learn and grow Familiarity with Git and HTML is beneficial Looking to build a long-term career in software engineering Based in or around Cheltenham, Gloucester, Worcester. Rise Technical Recruitment Ltd acts an employment agency for permanent roles and an employment business for temporary roles. The salary advertised is the bracket available for this position. The actual salary paid will be dependent on your level of experience, qualifications and skill set and will be decided by our client, the employer. Rise are not responsible or liable for any hiring decisions made by the end client. We are an equal opportunities company and welcome applications from all suitable candidates.
Mar 11, 2026
Full time
Graduate Software Engineer (2026 Graduate) Cheltenham £28,000 + Training + Progression + Pension An excellent opportunity awaits a 2026 graduate pursuing a career in software engineering. This role offers exposure to varied projects, strong mentorship, and the chance to grow within an established software business known for developing graduate talent.This company is a small but well-established software house, highly regarded in the engineering sector for delivering bespoke in-house software solutions for complex electronics projects.In this role, you will join a tight-knit, experienced development team. After initial training to learn the company's products and solutions, you will begin contributing to hands-on support and development tasks, building new features, fixing bugs, and assisting on projects that deliver robust and reliable software to a global customer base. As a graduate engineer, you will receive strong mentorship from senior engineers as you transition into industry. This role is based in Cheltenham, five days per week, to provide consistent support and development.The ideal candidate will be graduating in 2026 with a background in computer science, electronics, or a similar field, and will be keen to pursue a career in software engineering. Candidates should have a solid understanding and practical experience with object?oriented programming, particularly C++. An interest in electronics, geometry, complex algorithms, or graphics will be beneficial.This is a fantastic opportunity for a graduate to gain broad hands-on experience, develop as a software engineer, and build a long-term career within a respected engineering business. The Role: Software development, maintaining and creating new features Exposure to real commercial projects, bug fixing, and team collaboration Extensive training, mentorship, and clear progression path Office-based in Cheltenham The Person: 2026 Graduate, looking to pursue a career in software engineering Hands on expereince with C++, with a willingness to learn and grow Familiarity with Git and HTML is beneficial Looking to build a long-term career in software engineering Based in or around Cheltenham, Gloucester, Worcester. Rise Technical Recruitment Ltd acts an employment agency for permanent roles and an employment business for temporary roles. The salary advertised is the bracket available for this position. The actual salary paid will be dependent on your level of experience, qualifications and skill set and will be decided by our client, the employer. Rise are not responsible or liable for any hiring decisions made by the end client. We are an equal opportunities company and welcome applications from all suitable candidates.
Generative Biology Institute The Generative Biology Institute (GBI) is tackling the key challenges in making biology engineerable, and thereby unlocking the unrivalled power of biology for the benefit of humanity. GBI is part of the Ellison Institute of Technology, Oxford (EIT) and is led by founding Director Jason Chin. The vision of the Generative Biology Institute is to lay the foundations for engineering biology, and unlock its potential for good. To achieve this, we must overcome two key challenges. First, we need the ability to write in the natural language of biology, enabling the rapid and scalable synthesis of entire genomes with precision. Second, we must understand what to write - determining which DNA sequences will generate biological systems that perform the desired functions. Addressing these challenges will allow us to harness the full power of biology to create transformative solutions across health, agriculture, clean energy and more. GBI will have sustained and substantial funding to support the unique scale and ambition of its ground-breaking vision for engineering biology. GBI researchers will also be supported by cutting-edge technology hubs including mass spectrometry, flow cytometry, sequencing, automation, imaging, and bioprocessing. GBI will also have access to substantial compute resources that can be leveraged to further accelerate progress, including scientific compute, bioinformatics, and machine learning. The environment at GBI will allow researchers to undertake ambitious, long-term, collaborative research, and we will actively support the translation of research to commercial applications, where appropriate. The Generative Biology Institute will commence operations in a newly renovated bespoke space in the Oxford Science Park. The team will later move to a purpose-made facility in the Oxford Science Park, currently under construction. Once complete, this state-of-the art facility will include more than 40,000 m of research laboratory and office space.It will house over 30 groups and up to 600 employees at scale, focused on solving the two critical challenges in making biology engineerable and applying the solutions to addressing the global challenges encapsulated in EIT's Humane Endeavors. Job Summary The Generative Biology Institute (GBI) is seeking enthusiastic and motivated Research Assistants to join the institute. This role is ideal for individuals looking to apply their academic training in a practical, research-intensive environment. Research Assistants will support ongoing research projects within one or more GBI research groups, assisting with experimental work, data collection and analysis, and the development and maintenance of laboratory capabilities. You will also contribute to the preparation of scientific reports, presentations, and other research outputs, working closely with researchers across GBI in a collaborative and well resourced setting dedicated to advancing engineering biology at scale. Applications to Research Groups Applicants are required to apply to specific research groups as part of their application. On the application form, you may select up to three (3) research groups. In your cover letter, please clearly indicate the group(s) you are applying to and describe your interest, relevant skills, and experience for each. Applications that do not specify research group preferences, or that select more than three groups, will not be considered. All applications must be submitted exclusively through the EIT job portal. Please do not contact Principal Investigators directly, as direct outreach will not be considered as part of the application process. Due to the volume of applications, the review and decision process may take 3-6 months. Principal Investigators currently recruiting for Research Assistants: Leopold Parts - The Parts group works to engineer and model mammalian chromosomes. In particular, the group has long term aims to delete, randomize, evolve, and model chromosome scale DNA, all with the aim of informing models of synthetic DNA function; other ideas fitting this broad remit are very welcome. Rongzhen Tian - The Tian group aims to leverage an orthogonal replication system for the accelerated evolution of complex biological functions to i) advance fundamental scientific understanding of molecular and cellular evolution, ii) develop biomolecules to tackle challenges in human health and industry, and iii) generate large scale enzyme datasets for training next generation protein design models. Jérôme Zürcher - The Zürcher group aims to develop methodology to rapidly and scalably write entire genomes of microbes and phages and to leverage these methods to i) genetically isolate organisms, ii) investigate host pathogen interactions, iii) provide a platform for large vector assembly towards Gb scale genome synthesis. Linda van Bijsterveldt - The van Bijsterveldt group aims to develop methods for building and stably transmitting synthetic chromosomes through mitosis and meiosis in mammals and plants. Projects focus on i) creating scalable platforms for constructing entire genomes, ii) transferring chromosomes between different species, and iii) controlling trait inheritance patterns. Kiarash Jamali - The Jamali group focuses on integrating novel, large databases and inductive biases in generative models of biomolecules, seeking to create next generation tools that would enable protein design of new to nature enzymatic reactions, therapeutics, and molecular motors. A particular focus will be on the integration of learned machine learning force fields with generative protein modelling. Fabian Rehm - The Rehm group works to develop and apply new approaches for the continuous evolution of target genes, and the synthesis of large microbial genome stretches. Research will focus on i) evolving complex, multi gene traits within a single experiment, ii) building selective pressures that reward desired behaviours while minimising escape routes, iii) how to borrow principles from natural evolution, such as modularity, gene amplification, or cooperation, to help engineered organisms explore richer evolutionary pathways. Jason Chin - The Chin group's work pioneers: i) the development and application of genome design and synthesis methods and ii) combines these approaches with cellular engineering for the encoded cellular synthesis of new polymers and materials. Key Responsibilities for all Research Assistants: Assist in scientific studies and experiments by collecting and analysing data under the guidance of the senior scientists Perform routine laboratory tasks such as preparing samples, setting up equipment, and maintaining lab safety protocols Analyse experimental data using software tools. Prepare reports and presentations of findings Support the Research Group in the development of written materials, including publications, conference presentations and laboratory protocols Carry out desk based research to establish the state of the art in scientific areas related to the work of GBI Stay current on scientific advancements and technologies related to the field of synthetic biology through journals, conferences, and other academic resources Provide general day to day support to the wider team and any other duties requested of you by your group leader This list is not exhaustive and the role holder may be required to undertake additional tasks and duties commensurate with the role. Essential & Desirable Knowledge, Skills and Experience: A Bachelor's degree in a relevant scientific field (e.g. Biology, Chemistry, Engineering, Computer Science) Previous experience in working in a research laboratory Ability to work effectively in a high growth, fast paced, dynamic environment. Highly organised with an ability to manage multiple projects. Excellent oral and written communication skills, inter personal skills, and the ability to work with a wide range of people from diverse backgrounds. Experience with problem solving involving multiple internal and external stakeholders We offer the following salary and benefits: Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electrical Car Scheme Why work for EIT: At the Ellison Institute, we believe a collaborative, inclusive team is key to our success. We are building a supportive environment where creative risks are encouraged, and everyone feels heard. Valuing emotional intelligence, empathy, respect, and resilience, we encourage people to be curious and to have a shared commitment to excellence. Join us and make an impact! Terms of Appointment: You must have the right to work permanently in the UK with a willingness to travel as necessary. You will live in, or within easy commuting distance of, Oxford. During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme.
Mar 11, 2026
Full time
Generative Biology Institute The Generative Biology Institute (GBI) is tackling the key challenges in making biology engineerable, and thereby unlocking the unrivalled power of biology for the benefit of humanity. GBI is part of the Ellison Institute of Technology, Oxford (EIT) and is led by founding Director Jason Chin. The vision of the Generative Biology Institute is to lay the foundations for engineering biology, and unlock its potential for good. To achieve this, we must overcome two key challenges. First, we need the ability to write in the natural language of biology, enabling the rapid and scalable synthesis of entire genomes with precision. Second, we must understand what to write - determining which DNA sequences will generate biological systems that perform the desired functions. Addressing these challenges will allow us to harness the full power of biology to create transformative solutions across health, agriculture, clean energy and more. GBI will have sustained and substantial funding to support the unique scale and ambition of its ground-breaking vision for engineering biology. GBI researchers will also be supported by cutting-edge technology hubs including mass spectrometry, flow cytometry, sequencing, automation, imaging, and bioprocessing. GBI will also have access to substantial compute resources that can be leveraged to further accelerate progress, including scientific compute, bioinformatics, and machine learning. The environment at GBI will allow researchers to undertake ambitious, long-term, collaborative research, and we will actively support the translation of research to commercial applications, where appropriate. The Generative Biology Institute will commence operations in a newly renovated bespoke space in the Oxford Science Park. The team will later move to a purpose-made facility in the Oxford Science Park, currently under construction. Once complete, this state-of-the art facility will include more than 40,000 m of research laboratory and office space.It will house over 30 groups and up to 600 employees at scale, focused on solving the two critical challenges in making biology engineerable and applying the solutions to addressing the global challenges encapsulated in EIT's Humane Endeavors. Job Summary The Generative Biology Institute (GBI) is seeking enthusiastic and motivated Research Assistants to join the institute. This role is ideal for individuals looking to apply their academic training in a practical, research-intensive environment. Research Assistants will support ongoing research projects within one or more GBI research groups, assisting with experimental work, data collection and analysis, and the development and maintenance of laboratory capabilities. You will also contribute to the preparation of scientific reports, presentations, and other research outputs, working closely with researchers across GBI in a collaborative and well resourced setting dedicated to advancing engineering biology at scale. Applications to Research Groups Applicants are required to apply to specific research groups as part of their application. On the application form, you may select up to three (3) research groups. In your cover letter, please clearly indicate the group(s) you are applying to and describe your interest, relevant skills, and experience for each. Applications that do not specify research group preferences, or that select more than three groups, will not be considered. All applications must be submitted exclusively through the EIT job portal. Please do not contact Principal Investigators directly, as direct outreach will not be considered as part of the application process. Due to the volume of applications, the review and decision process may take 3-6 months. Principal Investigators currently recruiting for Research Assistants: Leopold Parts - The Parts group works to engineer and model mammalian chromosomes. In particular, the group has long term aims to delete, randomize, evolve, and model chromosome scale DNA, all with the aim of informing models of synthetic DNA function; other ideas fitting this broad remit are very welcome. Rongzhen Tian - The Tian group aims to leverage an orthogonal replication system for the accelerated evolution of complex biological functions to i) advance fundamental scientific understanding of molecular and cellular evolution, ii) develop biomolecules to tackle challenges in human health and industry, and iii) generate large scale enzyme datasets for training next generation protein design models. Jérôme Zürcher - The Zürcher group aims to develop methodology to rapidly and scalably write entire genomes of microbes and phages and to leverage these methods to i) genetically isolate organisms, ii) investigate host pathogen interactions, iii) provide a platform for large vector assembly towards Gb scale genome synthesis. Linda van Bijsterveldt - The van Bijsterveldt group aims to develop methods for building and stably transmitting synthetic chromosomes through mitosis and meiosis in mammals and plants. Projects focus on i) creating scalable platforms for constructing entire genomes, ii) transferring chromosomes between different species, and iii) controlling trait inheritance patterns. Kiarash Jamali - The Jamali group focuses on integrating novel, large databases and inductive biases in generative models of biomolecules, seeking to create next generation tools that would enable protein design of new to nature enzymatic reactions, therapeutics, and molecular motors. A particular focus will be on the integration of learned machine learning force fields with generative protein modelling. Fabian Rehm - The Rehm group works to develop and apply new approaches for the continuous evolution of target genes, and the synthesis of large microbial genome stretches. Research will focus on i) evolving complex, multi gene traits within a single experiment, ii) building selective pressures that reward desired behaviours while minimising escape routes, iii) how to borrow principles from natural evolution, such as modularity, gene amplification, or cooperation, to help engineered organisms explore richer evolutionary pathways. Jason Chin - The Chin group's work pioneers: i) the development and application of genome design and synthesis methods and ii) combines these approaches with cellular engineering for the encoded cellular synthesis of new polymers and materials. Key Responsibilities for all Research Assistants: Assist in scientific studies and experiments by collecting and analysing data under the guidance of the senior scientists Perform routine laboratory tasks such as preparing samples, setting up equipment, and maintaining lab safety protocols Analyse experimental data using software tools. Prepare reports and presentations of findings Support the Research Group in the development of written materials, including publications, conference presentations and laboratory protocols Carry out desk based research to establish the state of the art in scientific areas related to the work of GBI Stay current on scientific advancements and technologies related to the field of synthetic biology through journals, conferences, and other academic resources Provide general day to day support to the wider team and any other duties requested of you by your group leader This list is not exhaustive and the role holder may be required to undertake additional tasks and duties commensurate with the role. Essential & Desirable Knowledge, Skills and Experience: A Bachelor's degree in a relevant scientific field (e.g. Biology, Chemistry, Engineering, Computer Science) Previous experience in working in a research laboratory Ability to work effectively in a high growth, fast paced, dynamic environment. Highly organised with an ability to manage multiple projects. Excellent oral and written communication skills, inter personal skills, and the ability to work with a wide range of people from diverse backgrounds. Experience with problem solving involving multiple internal and external stakeholders We offer the following salary and benefits: Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electrical Car Scheme Why work for EIT: At the Ellison Institute, we believe a collaborative, inclusive team is key to our success. We are building a supportive environment where creative risks are encouraged, and everyone feels heard. Valuing emotional intelligence, empathy, respect, and resilience, we encourage people to be curious and to have a shared commitment to excellence. Join us and make an impact! Terms of Appointment: You must have the right to work permanently in the UK with a willingness to travel as necessary. You will live in, or within easy commuting distance of, Oxford. During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme.