Senior Bioanalytical ADME/DMPK Scientist

Job Role: Senior Bioanalytical ADME/DMPK Scientist
Site: Chapel-en-le-Frith
Salary: up to £40,000 p/a

Concept Life Sciences seeks a Senior Bioanalytical ADME/DMPK Scientist to primarily assist with discovery bioanalysis and PK/PD analyses, whilst supporting all functions of the ADME/DMPK team, including potential cross-functionality across in vitro ADME assays. This exciting diverse role will support the rapid growth and continued success of the ADME/DMPK team, utilising the new state of the art laboratories at our Chapel en le Frith site.

You will work closely with our Team Leaders, designing, organising, performing, processing, reviewing and reporting studies, engaging with clients and other departments across our sites, and contributing to process improvement during the expansion of the team's capacity and capabilities. This role will be laboratory based primarily but will have a lot of input into how bioanalysis and PK/PD analysis is performed, including influence over systems and processes, vendors, consumables, instruments and equipment. Development will be offered at every possible step, including internal mentorship and external seminars/conferences/courses, and innovation and independence are desired to contribute to this progression of our science and standards!

• You are an independent and self motivated, experienced Scientist, with extensive bioanalytical experience, including method development and sample analysis across a variety of molecules, matrices and extraction methods (small molecules, peptides, prodrugs; plasma, blood, brain, heart; PPT, SPE, LLE).
• You have experience processing, interpreting and troubleshooting bioanalytical and PK/PD data, utilising Excel and Phoenix WinNonLin software.
• You are adept at using, maintaining, and troubleshooting LC MS/MS, and potentially UV LC systems, ideally Waters instruments and associated software (MassLynx, TargetLynx, Trendplot).
• You will understand in life study design and be able to contribute to discussions regarding study variables and how they will impact outcomes, to inform client decisions
• You have excellent written and verbal communication skills; you will be comfortable reporting and presenting your research to colleagues and clients alike.
• You are confident scheduling, prioritising and delegating studies and tasks, and have a punctual conscientious disposition towards deadlines
• You will have a B.Sc. or M.Sc. in a relevant field.
  

• DMPK experience as a project representative or otherwise
• In vitro ADME assay experience; performing, processing and reporting
• High resolution MS operation and troubleshooting experience
• Metabolite Identification experience
  

In addition to a competitive salary, we provide generous holiday entitlement, a pension scheme with enhanced employer contributions, a health cash plan covering a range of therapy treatments, a cycle to work scheme, a retail discount scheme, death in service benefit, a discretionary bonus scheme, and free on site parking.

You'll also have access to our BHN Extras platform, offering cashback, discounts, and tech/home purchases via salary sacrifice.

Colleague wellbeing is important to us; we offer 24/7 virtual GP access, emotional support services, and a comprehensive wellbeing hub. We're proud of our inclusive, supportive culture and provide a range of learning and development opportunities to help you grow both personally and professionally.

Concept Life Sciences is a multi disciplined Contract Research Organisation based in the UK providing market leading scientific services globally. Over the past 25 years, Concept Life Sciences and its heritage companies have played a pivotal role in guiding numerous clients along their path to clinical success and many of these clients have evolved into enduring scientific collaborators.

From our 4 sites across the UK, we provide world leading expertise to the pharmaceutical, biotech, agrochemical, and material science industries. We have clients across Europe, Asia, and the US, who value our knowledge based, science led, and customer focused approach.