Why Faculty? We established Faculty in 2014 because we thought that AI would be the most important technology of our time. Since then, we've worked with over 350 global customers to transform their performance through human centric AI. You can read about our real world impact here. We don't chase hype cycles. We innovate, build and deploy responsible AI which moves the needle - and we know a thing or two about doing it well. We bring an unparalleled depth of technical, product and delivery expertise to our clients who span government, finance, retail, energy, life sciences and defence. Our business, and reputation, is growing fast and we're always on the lookout for individuals who share our intellectual curiosity and desire to build a positive legacy through technology. AI is an epoch defining technology, join a company where you'll be empowered to envision its most powerful applications, and to make them happen. About the team Faculty conducts critical red teaming and builds evaluations for misuse capabilities in sensitive areas, such as CBRN, cybersecurity and international security, for several leading frontier model developers and national safety institutes; notably, our work has been featured in OpenAI's system card for o1. Our commitment also extends to conducting fundamental technical research on mitigation strategies, with our findings published in peer reviewed conferences and delivered to national security institutes. Complementing this, we design evaluations for model developers across broader safety relevant fields, including the societal impacts of increasingly capable frontier models, showcasing our expertise across the safety landscape. About the role The Principal Research Scientist for AI Safety will be the driving force behind Faculty's small, high agency research team, shaping the future of safe AI systems. You will lead the scientific research agenda for AI safety, focusing on large language models and other critical systems. This role involves leading researchers, driving external publications, and ensuring alignment with Faculty's commercial ambition to build trustworthy AI, giving you the opportunity to make a high impact contribution in a rapidly evolving, critical field. What you'll be doing: Leading the AI safety team's ambitious research agenda, setting priorities aligned with long term company goals. Conducting and overseeing cutting edge AI safety research, specifically for large language models and safety critical AI systems. Publishing high impact research findings in leading academic conferences and journals. Shaping the research agenda by identifying impactful opportunities and balancing scientific and practical priorities. Helping to build and mentor a growing team of researchers, fostering an innovative and collaborative culture. Collaborating on delivery of evaluations and red teaming projects in high risk domains like CBRN and cybersecurity. Position Faculty as a thought leader in AI safety through research and strategic stakeholder engagement. Who we're looking for: You have a proven track record of high impact AI research, demonstrated through top tier academic publications or equivalent experience. You possess deep domain knowledge in language models and the evolving field of AI safety. You exhibit strong research judgment and extensive experience in AI safety, including generating and executing novel research directions. You have the ability to conduct and oversee complex technical research projects, with advanced programming skills (Python, standard data science stack) to review team work. You bring excellent verbal and written communication skills, capable of sharing complex ideas with diverse audiences. You have a deep understanding of the AI safety research landscape and the ability to build connections to secure resources for impactful work. Our Interview Process Talent Team Screen (30 mins) Experience & Theory interview (45 mins) Research presentation and coding interview (75 mins) Leadership and Principles interview (60 mins) Final stage with our CEO (45 mins) Our Recruitment Ethos We aim to grow the best team - not the most similar one. We know that diversity of individuals fosters diversity of thought, and that strengthens our principle of seeking truth. And we know from experience that diverse teams deliver better work, relevant to the world in which we live. We're united by a deep intellectual curiosity and desire to use our abilities for measurable positive impact. We strongly encourage applications from people of all backgrounds, ethnicities, genders, religions and sexual orientations. Some of our standout benefits: Unlimited Annual Leave Policy Private healthcare and dental Enhanced parental leave Family Friendly Flexibility & Flexible working Sanctus Coaching Hybrid Working (2 days in our Old Street office, London) If you don't feel you meet all the requirements, but are excited by the role and know you bring some key strengths, please do apply or reach out to our Talent Acquisition team for a confidential chat - Please know we are open to conversations about part time roles or condensed hours.
Feb 05, 2026
Full time
Why Faculty? We established Faculty in 2014 because we thought that AI would be the most important technology of our time. Since then, we've worked with over 350 global customers to transform their performance through human centric AI. You can read about our real world impact here. We don't chase hype cycles. We innovate, build and deploy responsible AI which moves the needle - and we know a thing or two about doing it well. We bring an unparalleled depth of technical, product and delivery expertise to our clients who span government, finance, retail, energy, life sciences and defence. Our business, and reputation, is growing fast and we're always on the lookout for individuals who share our intellectual curiosity and desire to build a positive legacy through technology. AI is an epoch defining technology, join a company where you'll be empowered to envision its most powerful applications, and to make them happen. About the team Faculty conducts critical red teaming and builds evaluations for misuse capabilities in sensitive areas, such as CBRN, cybersecurity and international security, for several leading frontier model developers and national safety institutes; notably, our work has been featured in OpenAI's system card for o1. Our commitment also extends to conducting fundamental technical research on mitigation strategies, with our findings published in peer reviewed conferences and delivered to national security institutes. Complementing this, we design evaluations for model developers across broader safety relevant fields, including the societal impacts of increasingly capable frontier models, showcasing our expertise across the safety landscape. About the role The Principal Research Scientist for AI Safety will be the driving force behind Faculty's small, high agency research team, shaping the future of safe AI systems. You will lead the scientific research agenda for AI safety, focusing on large language models and other critical systems. This role involves leading researchers, driving external publications, and ensuring alignment with Faculty's commercial ambition to build trustworthy AI, giving you the opportunity to make a high impact contribution in a rapidly evolving, critical field. What you'll be doing: Leading the AI safety team's ambitious research agenda, setting priorities aligned with long term company goals. Conducting and overseeing cutting edge AI safety research, specifically for large language models and safety critical AI systems. Publishing high impact research findings in leading academic conferences and journals. Shaping the research agenda by identifying impactful opportunities and balancing scientific and practical priorities. Helping to build and mentor a growing team of researchers, fostering an innovative and collaborative culture. Collaborating on delivery of evaluations and red teaming projects in high risk domains like CBRN and cybersecurity. Position Faculty as a thought leader in AI safety through research and strategic stakeholder engagement. Who we're looking for: You have a proven track record of high impact AI research, demonstrated through top tier academic publications or equivalent experience. You possess deep domain knowledge in language models and the evolving field of AI safety. You exhibit strong research judgment and extensive experience in AI safety, including generating and executing novel research directions. You have the ability to conduct and oversee complex technical research projects, with advanced programming skills (Python, standard data science stack) to review team work. You bring excellent verbal and written communication skills, capable of sharing complex ideas with diverse audiences. You have a deep understanding of the AI safety research landscape and the ability to build connections to secure resources for impactful work. Our Interview Process Talent Team Screen (30 mins) Experience & Theory interview (45 mins) Research presentation and coding interview (75 mins) Leadership and Principles interview (60 mins) Final stage with our CEO (45 mins) Our Recruitment Ethos We aim to grow the best team - not the most similar one. We know that diversity of individuals fosters diversity of thought, and that strengthens our principle of seeking truth. And we know from experience that diverse teams deliver better work, relevant to the world in which we live. We're united by a deep intellectual curiosity and desire to use our abilities for measurable positive impact. We strongly encourage applications from people of all backgrounds, ethnicities, genders, religions and sexual orientations. Some of our standout benefits: Unlimited Annual Leave Policy Private healthcare and dental Enhanced parental leave Family Friendly Flexibility & Flexible working Sanctus Coaching Hybrid Working (2 days in our Old Street office, London) If you don't feel you meet all the requirements, but are excited by the role and know you bring some key strengths, please do apply or reach out to our Talent Acquisition team for a confidential chat - Please know we are open to conversations about part time roles or condensed hours.
Vacancies Senior Principal Scientist Global Safety Job Introduction Thanks for checking out our vacancy, we're delighted you want to learn more about Dechra. We are a growing, global specialist within the world of veterinary pharmaceuticals. Our expertise is in the development, manufacture, marketing and sales of high quality products exclusively for veterinarians worldwide. Here at Dechra, our values are embedded within our culture and thrive within our family of almost 3000 colleagues globally. From manufacturing to marketing, (D)edication, (E)njoyment, (C)ourage, (H)onesty, (R)elationships and (A)mbition are at the heart of our everyday operations and the way we do business. This role can be performed remotely in any European Dechra entity. The Opportunity Dechra is a UK-based, global business involved in the development and marketing of veterinary products primarily for dogs, cats, horses. Global Safety at Dechra provides safety expertise for early-stage drug development programs through to marketed products. Main Responsibilities Serves as the Safety Technical Lead in Project Teams to define and implement safety strategy Has knowledge of regulatory requirements for safety and toxicology testing for drug development, preferably in the veterinary space, and serves as a resource for this information, ensuring that appropriate elements of safety and toxicity are addressed in data collected to support regulatory submissions Directs and delivers the design, execution, interpretation, and reporting of safety studies Responsible for the preparation of animal and human health risk assessments using where appropriate established requirements and the generation of toxicological data required to establish MOE, ADI, POD, and MRL values Manages both internal and external resources for the execution of safety strategies Responsible for presentations or discussions with VMD, EMA, FDA and other relevant regulatory agencies on issues related to safety; prepares data reviews or position papers to resolve regulatory issues pertaining to drug safety Responsible for the preparation of drug submissions for Veterinary Medicinal Products / New Animal Drugs May serve as a Project Lead to progress projects through Research and Development May contribute to the safety evaluation of new pipeline opportunities through close collaboration with Business Development May perform safety risk assessments to determine the impact of quality deviations for marketed veterinary products May serve as a mentor to more junior personnel Publishes research in peer reviewed publications, and presents research at internal and external scientific venues, as appropriate Ideal Candidate Here at Dechra we pride ourselves on being an inclusive employer and we embrace candidates from all walks of life. We're particularly keen to hear from those who have/are: PhD in scientific field with a minimum of 7 years relevant industry experience or a Master's degree with a minimum of 15 years relevant experience Demonstrated experience in non-clinical drug development Knowledge of Good Laboratory Practices (GLP) Ability to work independently with minimal oversight Ability to balance risk taking, opportunities and probability of success Ability to influence through persuasion Desirable Board certification in toxicology (DABT, ERT) preferred All applications received are reviewed by our internal talent acquisition team and we will get in touch if your skills and experience match what we're looking for. Should you not hear back from us within 28 days please don't be too disappointed - we may keep your CV on our database for any future vacancies which may be suitable and we encourage you to keep an eye on our careers site. For any questions or queries, please contact us at
Feb 04, 2026
Full time
Vacancies Senior Principal Scientist Global Safety Job Introduction Thanks for checking out our vacancy, we're delighted you want to learn more about Dechra. We are a growing, global specialist within the world of veterinary pharmaceuticals. Our expertise is in the development, manufacture, marketing and sales of high quality products exclusively for veterinarians worldwide. Here at Dechra, our values are embedded within our culture and thrive within our family of almost 3000 colleagues globally. From manufacturing to marketing, (D)edication, (E)njoyment, (C)ourage, (H)onesty, (R)elationships and (A)mbition are at the heart of our everyday operations and the way we do business. This role can be performed remotely in any European Dechra entity. The Opportunity Dechra is a UK-based, global business involved in the development and marketing of veterinary products primarily for dogs, cats, horses. Global Safety at Dechra provides safety expertise for early-stage drug development programs through to marketed products. Main Responsibilities Serves as the Safety Technical Lead in Project Teams to define and implement safety strategy Has knowledge of regulatory requirements for safety and toxicology testing for drug development, preferably in the veterinary space, and serves as a resource for this information, ensuring that appropriate elements of safety and toxicity are addressed in data collected to support regulatory submissions Directs and delivers the design, execution, interpretation, and reporting of safety studies Responsible for the preparation of animal and human health risk assessments using where appropriate established requirements and the generation of toxicological data required to establish MOE, ADI, POD, and MRL values Manages both internal and external resources for the execution of safety strategies Responsible for presentations or discussions with VMD, EMA, FDA and other relevant regulatory agencies on issues related to safety; prepares data reviews or position papers to resolve regulatory issues pertaining to drug safety Responsible for the preparation of drug submissions for Veterinary Medicinal Products / New Animal Drugs May serve as a Project Lead to progress projects through Research and Development May contribute to the safety evaluation of new pipeline opportunities through close collaboration with Business Development May perform safety risk assessments to determine the impact of quality deviations for marketed veterinary products May serve as a mentor to more junior personnel Publishes research in peer reviewed publications, and presents research at internal and external scientific venues, as appropriate Ideal Candidate Here at Dechra we pride ourselves on being an inclusive employer and we embrace candidates from all walks of life. We're particularly keen to hear from those who have/are: PhD in scientific field with a minimum of 7 years relevant industry experience or a Master's degree with a minimum of 15 years relevant experience Demonstrated experience in non-clinical drug development Knowledge of Good Laboratory Practices (GLP) Ability to work independently with minimal oversight Ability to balance risk taking, opportunities and probability of success Ability to influence through persuasion Desirable Board certification in toxicology (DABT, ERT) preferred All applications received are reviewed by our internal talent acquisition team and we will get in touch if your skills and experience match what we're looking for. Should you not hear back from us within 28 days please don't be too disappointed - we may keep your CV on our database for any future vacancies which may be suitable and we encourage you to keep an eye on our careers site. For any questions or queries, please contact us at
Job Details: Principal Formulation Development Scientist I Full details of the job. Vacancy Name Vacancy Name Principal Formulation Development Scientist I Vacancy No Vacancy No VN705 Employment Type Employment Type Permanent Location of role Location of role Oxford, UK Department Department CMC Key Responsibilities The primary purpose of this role is to serve as a recognized technical leader in formulation development, leveraging extensive experience and expert knowledge to drive innovation and contribute to the company's scientific strategy. The incumbent is expected to advocate for process, platform, and technology improvements, and apply advanced knowledge of scientific principles and the drug development process to solve extremely complex problems. The individual will exercise independent judgment in developing methods and techniques, consistently making the right calls to achieve results. This position will be responsible for conducting and designing experimental investigations to support a low & high dose parenteral bio pharmaceutical in the development and management of integrated formulation strategies supporting Immunocore's bio pharmaceutical platforms. The formulation role will be a hands on role, primarily focussed on lab work designing and performing experimental work. It will also cover drug delivery approaches, investigate novel technologies such as LNP, Pegylation and other delivery systems applicable to biologicals. The role will also cover early stressing studies, formulation excipient screening, CMC process support, drug substance and drug product through to compatibility with final patient delivery systems. Support and direct IUS studies and progress the clinical programmes. Support and respond to main stakeholders, for example Clinical and Regulatory teams, in the delivery of the clinical strategies. To work in close collaboration with the Head of Formulation, CMC teams and related functions to input into the formulation related sections for regulatory filings, development reports and other development related documents. Advanced people management skills are essential, including managing changing priorities while maintaining team motivation. They will create a safe environment for learning from mistakes, establish clear career paths, and hold career development conversations. The individual will engage in difficult conversations where appropriate, inspire action, and show employees how they contribute to higher goals. Conducting experiments, observing, interpreting and responding to results. Maintaining and increasing technical knowledge in relevant fields through self study, observation, attending relevant conferences and training courses. Maintaining accurate records of all work by completing laboratory notebooks on time, following Company procedures. Ensuring that laboratory equipment is operated in accordance with safety and risk guidelines; acting promptly to report any faults or problems to the relevant member of staff. Operating in accordance with the Company's Health and Safety policies, especially within a laboratory environment. Specific Responsibilities Experiments: independently testing and, increasingly, leading lines of investigation. Proposing new experiments based on emerging data and other related information. Providing support on technical aspects to others. Specifically: Develop drug delivery approaches for the biologics portfolio. Bring in new technologies exploring new administration approaches. To conduct and design experiments to establish formulations for TCR platform API and IMP. Lead and direct pre formulation, cycle 1,2 and 3 activities. Conduct drug presentation studies to evaluate alternative drug administration routes (e.g. sub cut). Represent formulation in CMC teams. Investigate compatibility of drug product through delivery devices for patient administration. Investigations in novel drug delivery formats. Perform testing and develop test methods to support stability and formulation studies. Carry out and optimise production of recombinant protein supportive reagents, including conjugations. Communicate key findings to managers and scientists in other groups. Review/sign off of routine assays. Writing of SOPs. Contributing to regulatory documentation. Participation in laboratory maintenance. Perform IUS studies. Perform clinical compatibility studies. Direct investigations into IUS clinical site excursion event impacts. Identify new external scientific technology and collaborations. Introduce new science into the group. Hand on practical role. Priorities: establishing priorities for own work and team based projects; making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance. Technical Knowledge: sharing knowledge with the wider team and across departments representing the department both internally and externally. May also act as a mentor or manager to other colleagues, especially new hires, sharing scientific and company knowledge. Increasingly providing analysis of new techniques and theories from outside the Company to advance the way the company works; sharing these with leaders across the Company. Laboratory records: ensuring that all records and information are up to date, on time and recorded to the correct standard. Supporting and encouraging others to achieve this. Laboratory equipment: providing technical guidance to others within the team on how to use equipment most effectively; making recommendations regarding acquisition of new pieces of equipment. Health & Safety: championing and helping others to understand H&S within the company, providing ad hoc training as required. Reporting: communicating and presenting research findings at meetings with colleagues, senior management and partners. Experience and Knowledge Essential Background in recombinant protein or antibody formulation, drug delivery of biologics, analytical development or protein characterisation, with proven industry experience and exposure to formulation strategies. Experience in design of formulation studies, including the utilisation of design of experiments principles. Strong expertise in electrophoretic or chromatographic assays and general biochemical lab techniques. Desirable Experience of process development for production of biologics and conjugation of biomolecules. Experience with lyophilisation development of Biotherapeutics. Familiar with biopharmaceutical stability study principles. Familiarity with novel drug delivery formats. Proactive in ensuring high quality of their work and seeking additional responsibilities to help meet the goals of the team. Presented detailed scientific findings and papers to internal and external audiences. Essential Qualifications PhD in bio manufacturing, protein engineering, biochemistry, molecular biology or related discipline. Industrial company experience delivering formulations through drug development phases. Normally requires a PhD in a scientific discipline and a minimum of 8+ years related experience; may include post doctoral experience. About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial stage T cell receptor biotechnology company whose purpose is to develop and commercialise a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first in class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognise that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
Feb 04, 2026
Full time
Job Details: Principal Formulation Development Scientist I Full details of the job. Vacancy Name Vacancy Name Principal Formulation Development Scientist I Vacancy No Vacancy No VN705 Employment Type Employment Type Permanent Location of role Location of role Oxford, UK Department Department CMC Key Responsibilities The primary purpose of this role is to serve as a recognized technical leader in formulation development, leveraging extensive experience and expert knowledge to drive innovation and contribute to the company's scientific strategy. The incumbent is expected to advocate for process, platform, and technology improvements, and apply advanced knowledge of scientific principles and the drug development process to solve extremely complex problems. The individual will exercise independent judgment in developing methods and techniques, consistently making the right calls to achieve results. This position will be responsible for conducting and designing experimental investigations to support a low & high dose parenteral bio pharmaceutical in the development and management of integrated formulation strategies supporting Immunocore's bio pharmaceutical platforms. The formulation role will be a hands on role, primarily focussed on lab work designing and performing experimental work. It will also cover drug delivery approaches, investigate novel technologies such as LNP, Pegylation and other delivery systems applicable to biologicals. The role will also cover early stressing studies, formulation excipient screening, CMC process support, drug substance and drug product through to compatibility with final patient delivery systems. Support and direct IUS studies and progress the clinical programmes. Support and respond to main stakeholders, for example Clinical and Regulatory teams, in the delivery of the clinical strategies. To work in close collaboration with the Head of Formulation, CMC teams and related functions to input into the formulation related sections for regulatory filings, development reports and other development related documents. Advanced people management skills are essential, including managing changing priorities while maintaining team motivation. They will create a safe environment for learning from mistakes, establish clear career paths, and hold career development conversations. The individual will engage in difficult conversations where appropriate, inspire action, and show employees how they contribute to higher goals. Conducting experiments, observing, interpreting and responding to results. Maintaining and increasing technical knowledge in relevant fields through self study, observation, attending relevant conferences and training courses. Maintaining accurate records of all work by completing laboratory notebooks on time, following Company procedures. Ensuring that laboratory equipment is operated in accordance with safety and risk guidelines; acting promptly to report any faults or problems to the relevant member of staff. Operating in accordance with the Company's Health and Safety policies, especially within a laboratory environment. Specific Responsibilities Experiments: independently testing and, increasingly, leading lines of investigation. Proposing new experiments based on emerging data and other related information. Providing support on technical aspects to others. Specifically: Develop drug delivery approaches for the biologics portfolio. Bring in new technologies exploring new administration approaches. To conduct and design experiments to establish formulations for TCR platform API and IMP. Lead and direct pre formulation, cycle 1,2 and 3 activities. Conduct drug presentation studies to evaluate alternative drug administration routes (e.g. sub cut). Represent formulation in CMC teams. Investigate compatibility of drug product through delivery devices for patient administration. Investigations in novel drug delivery formats. Perform testing and develop test methods to support stability and formulation studies. Carry out and optimise production of recombinant protein supportive reagents, including conjugations. Communicate key findings to managers and scientists in other groups. Review/sign off of routine assays. Writing of SOPs. Contributing to regulatory documentation. Participation in laboratory maintenance. Perform IUS studies. Perform clinical compatibility studies. Direct investigations into IUS clinical site excursion event impacts. Identify new external scientific technology and collaborations. Introduce new science into the group. Hand on practical role. Priorities: establishing priorities for own work and team based projects; making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance. Technical Knowledge: sharing knowledge with the wider team and across departments representing the department both internally and externally. May also act as a mentor or manager to other colleagues, especially new hires, sharing scientific and company knowledge. Increasingly providing analysis of new techniques and theories from outside the Company to advance the way the company works; sharing these with leaders across the Company. Laboratory records: ensuring that all records and information are up to date, on time and recorded to the correct standard. Supporting and encouraging others to achieve this. Laboratory equipment: providing technical guidance to others within the team on how to use equipment most effectively; making recommendations regarding acquisition of new pieces of equipment. Health & Safety: championing and helping others to understand H&S within the company, providing ad hoc training as required. Reporting: communicating and presenting research findings at meetings with colleagues, senior management and partners. Experience and Knowledge Essential Background in recombinant protein or antibody formulation, drug delivery of biologics, analytical development or protein characterisation, with proven industry experience and exposure to formulation strategies. Experience in design of formulation studies, including the utilisation of design of experiments principles. Strong expertise in electrophoretic or chromatographic assays and general biochemical lab techniques. Desirable Experience of process development for production of biologics and conjugation of biomolecules. Experience with lyophilisation development of Biotherapeutics. Familiar with biopharmaceutical stability study principles. Familiarity with novel drug delivery formats. Proactive in ensuring high quality of their work and seeking additional responsibilities to help meet the goals of the team. Presented detailed scientific findings and papers to internal and external audiences. Essential Qualifications PhD in bio manufacturing, protein engineering, biochemistry, molecular biology or related discipline. Industrial company experience delivering formulations through drug development phases. Normally requires a PhD in a scientific discipline and a minimum of 8+ years related experience; may include post doctoral experience. About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial stage T cell receptor biotechnology company whose purpose is to develop and commercialise a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first in class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognise that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
Principal Automation Scientist, In Vitro Cell based Screening and Mechanistic Profiling Category: Research Location: Oxford, South East, GB This role isn't just about doing science - it's about reinventing how it's done. As a subject matter expert you will lead initiatives to transform functional genomics and cell based screening through automation and application of digital tools, turning in vitro discovery into a smarter, faster engine for breakthrough targets. Your new role As a Principal Automation Scientist in the In Vitro Discovery & Delivery (IDD) department, you will define and deploy automation solutions and implement digital applications to accelerate data generation for in vitro functional genomics, cell based screening, and large scale mechanistic profiling. You will lead the design, deployment and adoption of automated solutions tailored to complex in vitro cell based workflows, drive the choice and use of digital data applications and FAIR aligned practices to scale throughput, and ensure reproducibility for predictive target discovery across the IDD team based in Oxford. You will be instrumental in the team's ability to generate high quality multi modal datasets to improve the probability of success for novel targets and pipeline projects, supporting more informed target nominations and de risking portfolio decisions. Your responsibilities will include: Strategic leadership: Define roadmaps and cross functional programs to transform in vitro target discovery through automation, advanced data capture and multi omic integration. Automation & digital systems: Evaluate and implement scalable, production ready solutions (robotics, LIMS/ELN integrations, data and imaging pipelines) to standardise experimental execution and data capture. FAIR data & tooling: Drive enterprise adoption of FAIR principles; set metadata, data model and standards and champion data provenance and accessibility. Advanced analysis & ML: Oversee statistical frameworks, scalable analysis pipelines and fuel machine learning models with data for predictive target discovery; ensure validation, explainability and deployment. Stakeholder engagement: Act as senior partner to Target Discovery, Functional Genomics, Technology Leaders, Digital Biology, Biology AI, IDD US and Novo Nordisk automation engineers; build external collaborations with vendors, CROs, academia and industry partners. Your new department The In Vitro Discovery & Delivery (IDD) department, based at Novo Nordisk Research Centre in Oxford is part of Novo Nordisk Global Research. As a state of the art target discovery and validation research department, it is responsible for identifying novel targets with mechanisms of action for diseases aligned with Novo Nordisk therapy area priorities. The centre uses innovative and unbiased in silico and in vitro human centric collaborative approaches to identify new therapeutic opportunities for type 2 diabetes and obesity, and their associated cardiometabolic co morbidities including MASH, and cardiovascular disease. The department also drives productive collaborations with academia (particularly the University of Oxford) and biotechnology partners. The In Vitro Science team is part of a global organisation, including a team based at the Novo Nordisk research centre in Boston. Together, we work closely with our therapy area partners in the Global Research in Boston and Denmark to progress novel targets into Novo Nordisk's early project pipeline. Your skills & qualifications PhD or MSc in life sciences, computational biology, or related field. Extensive experience with medium to high throughput in vitro functional genomics and cell based screening, automation and digital workflows. Proven track record implementing FAIR data practices and deploying digital tools to support data analytics at scale, ensuring future proof data usage. Strong coding, data engineering and automation platform experience; familiarity with cloud/ML pipelines desirable. Outstanding communication abilities and effective interpersonal collaboration skills. Working at Novo Nordisk Every day we seek the solutions that defeat serious chronic diseases. To do this, we approach our work with determination, constant curiosity and a commitment to finding better ways forward. For over 100 years, this dedication has driven us to build a company focused on lasting change for long term health. One where diverse thinking, shared purpose and mutual respect come together to create extraordinary results. When you join us, you're not just starting a job - you're becoming part of a story that spans generations. Deadline 13th February 2026. We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. At Novo Nordisk, we're not chasing quick fixes - we're creating lasting change for long term health. For over 100 years, we're driven by a single purpose: to defeat serious chronic diseases and help millions of people live healthier lives. This dedication fuels our constant curiosity and inspires us to push the boundaries of what's possible in healthcare. We embrace diverse perspectives, seek out bold ideas, and build partnerships rooted in shared purpose. Together, we're making healthcare more accessible, treating and preventing diseases, and pioneering solutions that create change spanning generations. When you join us, you become part of something bigger - a legacy of impact that reaches far beyond today.
Feb 03, 2026
Full time
Principal Automation Scientist, In Vitro Cell based Screening and Mechanistic Profiling Category: Research Location: Oxford, South East, GB This role isn't just about doing science - it's about reinventing how it's done. As a subject matter expert you will lead initiatives to transform functional genomics and cell based screening through automation and application of digital tools, turning in vitro discovery into a smarter, faster engine for breakthrough targets. Your new role As a Principal Automation Scientist in the In Vitro Discovery & Delivery (IDD) department, you will define and deploy automation solutions and implement digital applications to accelerate data generation for in vitro functional genomics, cell based screening, and large scale mechanistic profiling. You will lead the design, deployment and adoption of automated solutions tailored to complex in vitro cell based workflows, drive the choice and use of digital data applications and FAIR aligned practices to scale throughput, and ensure reproducibility for predictive target discovery across the IDD team based in Oxford. You will be instrumental in the team's ability to generate high quality multi modal datasets to improve the probability of success for novel targets and pipeline projects, supporting more informed target nominations and de risking portfolio decisions. Your responsibilities will include: Strategic leadership: Define roadmaps and cross functional programs to transform in vitro target discovery through automation, advanced data capture and multi omic integration. Automation & digital systems: Evaluate and implement scalable, production ready solutions (robotics, LIMS/ELN integrations, data and imaging pipelines) to standardise experimental execution and data capture. FAIR data & tooling: Drive enterprise adoption of FAIR principles; set metadata, data model and standards and champion data provenance and accessibility. Advanced analysis & ML: Oversee statistical frameworks, scalable analysis pipelines and fuel machine learning models with data for predictive target discovery; ensure validation, explainability and deployment. Stakeholder engagement: Act as senior partner to Target Discovery, Functional Genomics, Technology Leaders, Digital Biology, Biology AI, IDD US and Novo Nordisk automation engineers; build external collaborations with vendors, CROs, academia and industry partners. Your new department The In Vitro Discovery & Delivery (IDD) department, based at Novo Nordisk Research Centre in Oxford is part of Novo Nordisk Global Research. As a state of the art target discovery and validation research department, it is responsible for identifying novel targets with mechanisms of action for diseases aligned with Novo Nordisk therapy area priorities. The centre uses innovative and unbiased in silico and in vitro human centric collaborative approaches to identify new therapeutic opportunities for type 2 diabetes and obesity, and their associated cardiometabolic co morbidities including MASH, and cardiovascular disease. The department also drives productive collaborations with academia (particularly the University of Oxford) and biotechnology partners. The In Vitro Science team is part of a global organisation, including a team based at the Novo Nordisk research centre in Boston. Together, we work closely with our therapy area partners in the Global Research in Boston and Denmark to progress novel targets into Novo Nordisk's early project pipeline. Your skills & qualifications PhD or MSc in life sciences, computational biology, or related field. Extensive experience with medium to high throughput in vitro functional genomics and cell based screening, automation and digital workflows. Proven track record implementing FAIR data practices and deploying digital tools to support data analytics at scale, ensuring future proof data usage. Strong coding, data engineering and automation platform experience; familiarity with cloud/ML pipelines desirable. Outstanding communication abilities and effective interpersonal collaboration skills. Working at Novo Nordisk Every day we seek the solutions that defeat serious chronic diseases. To do this, we approach our work with determination, constant curiosity and a commitment to finding better ways forward. For over 100 years, this dedication has driven us to build a company focused on lasting change for long term health. One where diverse thinking, shared purpose and mutual respect come together to create extraordinary results. When you join us, you're not just starting a job - you're becoming part of a story that spans generations. Deadline 13th February 2026. We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. At Novo Nordisk, we're not chasing quick fixes - we're creating lasting change for long term health. For over 100 years, we're driven by a single purpose: to defeat serious chronic diseases and help millions of people live healthier lives. This dedication fuels our constant curiosity and inspires us to push the boundaries of what's possible in healthcare. We embrace diverse perspectives, seek out bold ideas, and build partnerships rooted in shared purpose. Together, we're making healthcare more accessible, treating and preventing diseases, and pioneering solutions that create change spanning generations. When you join us, you become part of something bigger - a legacy of impact that reaches far beyond today.
