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Senior Scientist Genomics - Pathogen
Ellison Institute, LLC Oxford, Oxfordshire
The Ellison Institute of Technology (EIT) tackles humanity's greatest challenges by turning science and technology into impactful global solutions. Focused on areas like health, food security, sustainable agriculture, climate change, clean energy, and robotics in an era of artificial intelligence. EIT blends groundbreaking research with practical applications to deliver lasting results. A cornerstone of EIT mission is its upcoming 300,000-square-foot research facility at the Oxford Science Park, set to open in 2027. This cutting-edge campus will feature advanced labs, an oncology and preventative care clinic, and collaborative spaces to strengthen its partnership with the University of Oxford. It will also host the Ellison Scholars, driving innovation for societal benefit. The Pathogen Mission highlights EIT's transformative approach, using Whole Genome Sequencing (WGS) and Oracle's cloud technology to create a global pathogen metagenomics system. This initiative aims to improve diagnostics, provide early epidemic warnings, and guide treatments by profiling antimicrobial resistance. The goal is to deliver certified diagnostic tools for widespread use in labs, hospitals, and public health. EIT fosters a culture of collaboration, innovation, and resilience, valuing diverse expertise to drive sustainable solutions to humanity's enduring challenges. We are seeking a highly skilled and innovative Senior Genomics Scientist to lead the establishment of high-throughput genomics capabilities within our Pathogen Program. This pivotal role will focus on developing and optimising robust sequencing workflows using both short-read (e.g., Illumina) and long-read (e.g., Oxford Nanopore Technologies, PacBio) platforms for the sequencing of pathogens. The successful candidate will drive the implementation of end-to-end genomics pipelines, from sample preparation through to sequencing and preliminary data analysis, while also supporting method development and scaling through laboratory automation. The scope of work may extend beyond the Pathogen Program, offering opportunities to collaborate across EIT's broader research initiatives. The position includes line management responsibilities, overseeing a team of 2-3 laboratory scientists, and will play a critical role in advancing EIT's mission to deliver cutting-edge genomic science for real-world impact. Key Responsibilities: Design, evaluate, and implement high-throughput sequencing workflows for pathogen genomics using short- and long-read technologies. Develop and optimise novel protocols and methodologies to address emerging research questions and challenges. Lead the integration of lab automation systems to streamline sample preparation and sequencing processes. Manage day-to-day operations of the sequencing team, including planning, performance tracking, and mentoring of junior scientists. Ensure quality control, data integrity, and reproducibility across all stages of the genomics workflow. Coordinate closely with bioinformatics teams to facilitate seamless handoff of data for analysis and interpretation. Provide scientific leadership and technical insight to support genomics needs across other programs at EIT. Keep abreast of technological advances and recommend adoption of relevant new platforms or strategies. Qualifications & Experience: Essential Knowledge, Skills and Experience: PhD in Genomics, Molecular Biology, Biotechnology, or a related field, or equivalent industrial experience. Proven track record (5+ years postdoctoral or equivalent industrial experience) in genomics and sequencing technologies. Demonstrated expertise in developing and troubleshooting NGS workflows, including both library prep and sequencing protocols. Experience with Illumina, ONT, and/or PacBio platforms. Strong leadership capabilities with prior experience managing laboratory personnel and projects. Excellent organizational, problem-solving, and communication skills. Desirable Knowledge, Skills and Experience: Experience implementing and operating lab automation platforms (e.g., liquid handlers, robotic systems). Proficiency in basic bioinformatics and data analysis, with the ability to build or oversee construction of data processing pipelines. Familiarity with quality management systems and standard operating procedures in high-throughput laboratory environments. Interest in cross-disciplinary collaboration, including applications of genomics in public health, diagnostics, or basic biology. We offer the following salary and benefits: Salary: Competitive salary on offer Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electrical Car Scheme Why work for EIT: At the Ellison Institute, we believe a collaborative, inclusive team is key to our success. We are building a supportive environment where creative risks are encouraged, and everyone feels heard. Valuing emotional intelligence, empathy, respect, and resilience, we encourage people to be curious and to have a shared commitment to excellence. Join us and make an impact! Terms of Appointment: You must have the right to work permanently in the UK with a willingness to travel as necessary. You will live in, or within easy commuting distance of, Oxford. During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme.
Sep 26, 2025
Full time
The Ellison Institute of Technology (EIT) tackles humanity's greatest challenges by turning science and technology into impactful global solutions. Focused on areas like health, food security, sustainable agriculture, climate change, clean energy, and robotics in an era of artificial intelligence. EIT blends groundbreaking research with practical applications to deliver lasting results. A cornerstone of EIT mission is its upcoming 300,000-square-foot research facility at the Oxford Science Park, set to open in 2027. This cutting-edge campus will feature advanced labs, an oncology and preventative care clinic, and collaborative spaces to strengthen its partnership with the University of Oxford. It will also host the Ellison Scholars, driving innovation for societal benefit. The Pathogen Mission highlights EIT's transformative approach, using Whole Genome Sequencing (WGS) and Oracle's cloud technology to create a global pathogen metagenomics system. This initiative aims to improve diagnostics, provide early epidemic warnings, and guide treatments by profiling antimicrobial resistance. The goal is to deliver certified diagnostic tools for widespread use in labs, hospitals, and public health. EIT fosters a culture of collaboration, innovation, and resilience, valuing diverse expertise to drive sustainable solutions to humanity's enduring challenges. We are seeking a highly skilled and innovative Senior Genomics Scientist to lead the establishment of high-throughput genomics capabilities within our Pathogen Program. This pivotal role will focus on developing and optimising robust sequencing workflows using both short-read (e.g., Illumina) and long-read (e.g., Oxford Nanopore Technologies, PacBio) platforms for the sequencing of pathogens. The successful candidate will drive the implementation of end-to-end genomics pipelines, from sample preparation through to sequencing and preliminary data analysis, while also supporting method development and scaling through laboratory automation. The scope of work may extend beyond the Pathogen Program, offering opportunities to collaborate across EIT's broader research initiatives. The position includes line management responsibilities, overseeing a team of 2-3 laboratory scientists, and will play a critical role in advancing EIT's mission to deliver cutting-edge genomic science for real-world impact. Key Responsibilities: Design, evaluate, and implement high-throughput sequencing workflows for pathogen genomics using short- and long-read technologies. Develop and optimise novel protocols and methodologies to address emerging research questions and challenges. Lead the integration of lab automation systems to streamline sample preparation and sequencing processes. Manage day-to-day operations of the sequencing team, including planning, performance tracking, and mentoring of junior scientists. Ensure quality control, data integrity, and reproducibility across all stages of the genomics workflow. Coordinate closely with bioinformatics teams to facilitate seamless handoff of data for analysis and interpretation. Provide scientific leadership and technical insight to support genomics needs across other programs at EIT. Keep abreast of technological advances and recommend adoption of relevant new platforms or strategies. Qualifications & Experience: Essential Knowledge, Skills and Experience: PhD in Genomics, Molecular Biology, Biotechnology, or a related field, or equivalent industrial experience. Proven track record (5+ years postdoctoral or equivalent industrial experience) in genomics and sequencing technologies. Demonstrated expertise in developing and troubleshooting NGS workflows, including both library prep and sequencing protocols. Experience with Illumina, ONT, and/or PacBio platforms. Strong leadership capabilities with prior experience managing laboratory personnel and projects. Excellent organizational, problem-solving, and communication skills. Desirable Knowledge, Skills and Experience: Experience implementing and operating lab automation platforms (e.g., liquid handlers, robotic systems). Proficiency in basic bioinformatics and data analysis, with the ability to build or oversee construction of data processing pipelines. Familiarity with quality management systems and standard operating procedures in high-throughput laboratory environments. Interest in cross-disciplinary collaboration, including applications of genomics in public health, diagnostics, or basic biology. We offer the following salary and benefits: Salary: Competitive salary on offer Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electrical Car Scheme Why work for EIT: At the Ellison Institute, we believe a collaborative, inclusive team is key to our success. We are building a supportive environment where creative risks are encouraged, and everyone feels heard. Valuing emotional intelligence, empathy, respect, and resilience, we encourage people to be curious and to have a shared commitment to excellence. Join us and make an impact! Terms of Appointment: You must have the right to work permanently in the UK with a willingness to travel as necessary. You will live in, or within easy commuting distance of, Oxford. During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme.
Senior Scientist (Next-generation sequencing) - Generative Biology Institute
Ellison Institute of Technology Oxford, Oxfordshire
The Ellison Institute of Technology (EIT) tackles humanity's greatest challenges by turning science and technology into impactful global solutions. Focused on areas like health, food security, sustainable agriculture, climate change, clean energy, and robotics in an era of artificial intelligence. EIT blends groundbreaking research with practical applications to deliver lasting results. A cornerstone of EIT mission is its upcoming 300,000-square-foot research facility at the Oxford Science Park, set to open in 2027. This cutting-edge campus will feature advanced labs, an oncology and preventative care clinic, and collaborative spaces to strengthen its partnership with the University of Oxford. It will also host the Ellison Scholars, driving innovation for societal benefit. The Generative Biology Institute (GBI) at the Ellison Institute of Technology (EIT) aims to overcome two major challenges in making biology engineerable: 1) the ability to precisely synthesize entire genomes, and 2) understanding which DNA sequences will create biological systems that perform desired functions. Solving these challenges will unlock the potential of biology for transformative solutions in health, sustainability, agriculture, and more. GBI will house 30 groups and over 300 researchers, supported by cutting-edge facilities and sustained funding to address global challenges and advance biology engineering. EIT fosters a culture of collaboration, innovation, and resilience, valuing diverse expertise to drive sustainable solutions to humanity's enduring challenges. Job Summary: We are seeking a highly motivated scientist to join as a foundingmember of our next-generation sequencing team within a dynamic research environment. Overall, this team will empower fellow scientists to confidently take full advantage of next-generation sequencing technology in their research. This team will manage the walk-up and supervised usage of Illumina, Nanopore, PacBio & Elements sequencing machines, be assisted by a state-of-the-art automation platform, and have access to a high-performance cluster for bioinformatic analysis. The successful candidate will play a key role in supporting research across multiple groups and themes by providing expertise in delivering high-quality sequencing data and developing innovative workflows that support a diversity of experimental applications. You will collaborate closely with research groups to design and execute sequencing strategies tailored to novel and emerging scientific questions, and such contributions will be equitably acknowledged through authorship on relevant outputs. Key Responsibilities: To design and perform sequencing workflows using a range of platforms (Illumina, Oxford Nanopore, PacBio and Elements) or other high-throughput platforms, adapting protocols as needed to meet experimental requirements. To design and execute bespoke sequencing experiments, collaborating with research teams working across niche and novel synthetic, molecular & cell biology applications. To train, assist and feedback to other scientists who can or wish to utilise next-generation sequencing in a walk-up fashion. To analyse sequencing data using existing bioinformatics tools and pipelines, and bespoke solutions if necessary, delivering actionable insights to collaborating scientists. To continuously curate an expert understanding on the underlying technologies in the full sequencing workflow (Experiment - DNA extraction - library preparation - sequencing - analysis, and associated QC steps). To have a close working relationship with scientists from automation and bioinformatics teams. To contribute to the maintenance, calibration, and troubleshooting of sequencing instruments, ensuring maximal performance and data quality. To stay abreast of new sequencing technologies and methodologies, integrating improvements to enhance performance, throughput and cost-efficiency. Essential Knowledge, Skills and Experience: A PhD (or equivalent industry experience) in a relevant field, such as genomics, molecular biology, synthetic biology, cell biology, or computational biology. Hands-on experience with next-generation sequencing technologies (e.g., Illumina, Oxford Nanopore). Proven ability to develop, adapt, and troubleshoot sequencing workflows. Familiarity with basic bioinformatics tools for sequencing analysis and interpretation OR confident in multiple programming languages and coding/simple software development. A track record of working effectively in a collaborative, multi-disciplinary research environment. Exceptional communication skills: possess a desire to understand the scientific requests of collaborators in depth, manage multiple continuous collaborations, and translate complex concepts and data interpretation into clear, actionable outputs for non-specialists. Desirable: Experience with LIMS, ELNs and data management. Experience in biological library screening, e.g. directed evolution, CRISPR screening, display technologies, deep mutational scanning. Experience with advanced sequencing techniques such as Hi-C, ChIP-Seq, SHAPE, nascent RNASeq. Experience in bioinformatics packages such as Nextflow, GATK, hifiasm. Experience with common programming languages such as Python, R, Unix. Experience with laboratory automation (e.g. Biomek i7) We offer the following salary and benefits: Salary: Competitive salary on offer Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electrical Car Scheme Why work for EIT: At the Ellison Institute, we believe a collaborative, inclusive team is key to our success. We are building a supportive environment where creative risks are encouraged, and everyone feels heard. Valuing emotional intelligence, empathy, respect, and resilience, we encourage people to be curious and to have a shared commitment to excellence. Join us and make an impact! Terms of Appointment: You must have the right to work permanently in the UK with a willingness to travel as necessary. You will live in, or within easy commuting distance of, Oxford. During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme.
Sep 23, 2025
Full time
The Ellison Institute of Technology (EIT) tackles humanity's greatest challenges by turning science and technology into impactful global solutions. Focused on areas like health, food security, sustainable agriculture, climate change, clean energy, and robotics in an era of artificial intelligence. EIT blends groundbreaking research with practical applications to deliver lasting results. A cornerstone of EIT mission is its upcoming 300,000-square-foot research facility at the Oxford Science Park, set to open in 2027. This cutting-edge campus will feature advanced labs, an oncology and preventative care clinic, and collaborative spaces to strengthen its partnership with the University of Oxford. It will also host the Ellison Scholars, driving innovation for societal benefit. The Generative Biology Institute (GBI) at the Ellison Institute of Technology (EIT) aims to overcome two major challenges in making biology engineerable: 1) the ability to precisely synthesize entire genomes, and 2) understanding which DNA sequences will create biological systems that perform desired functions. Solving these challenges will unlock the potential of biology for transformative solutions in health, sustainability, agriculture, and more. GBI will house 30 groups and over 300 researchers, supported by cutting-edge facilities and sustained funding to address global challenges and advance biology engineering. EIT fosters a culture of collaboration, innovation, and resilience, valuing diverse expertise to drive sustainable solutions to humanity's enduring challenges. Job Summary: We are seeking a highly motivated scientist to join as a foundingmember of our next-generation sequencing team within a dynamic research environment. Overall, this team will empower fellow scientists to confidently take full advantage of next-generation sequencing technology in their research. This team will manage the walk-up and supervised usage of Illumina, Nanopore, PacBio & Elements sequencing machines, be assisted by a state-of-the-art automation platform, and have access to a high-performance cluster for bioinformatic analysis. The successful candidate will play a key role in supporting research across multiple groups and themes by providing expertise in delivering high-quality sequencing data and developing innovative workflows that support a diversity of experimental applications. You will collaborate closely with research groups to design and execute sequencing strategies tailored to novel and emerging scientific questions, and such contributions will be equitably acknowledged through authorship on relevant outputs. Key Responsibilities: To design and perform sequencing workflows using a range of platforms (Illumina, Oxford Nanopore, PacBio and Elements) or other high-throughput platforms, adapting protocols as needed to meet experimental requirements. To design and execute bespoke sequencing experiments, collaborating with research teams working across niche and novel synthetic, molecular & cell biology applications. To train, assist and feedback to other scientists who can or wish to utilise next-generation sequencing in a walk-up fashion. To analyse sequencing data using existing bioinformatics tools and pipelines, and bespoke solutions if necessary, delivering actionable insights to collaborating scientists. To continuously curate an expert understanding on the underlying technologies in the full sequencing workflow (Experiment - DNA extraction - library preparation - sequencing - analysis, and associated QC steps). To have a close working relationship with scientists from automation and bioinformatics teams. To contribute to the maintenance, calibration, and troubleshooting of sequencing instruments, ensuring maximal performance and data quality. To stay abreast of new sequencing technologies and methodologies, integrating improvements to enhance performance, throughput and cost-efficiency. Essential Knowledge, Skills and Experience: A PhD (or equivalent industry experience) in a relevant field, such as genomics, molecular biology, synthetic biology, cell biology, or computational biology. Hands-on experience with next-generation sequencing technologies (e.g., Illumina, Oxford Nanopore). Proven ability to develop, adapt, and troubleshoot sequencing workflows. Familiarity with basic bioinformatics tools for sequencing analysis and interpretation OR confident in multiple programming languages and coding/simple software development. A track record of working effectively in a collaborative, multi-disciplinary research environment. Exceptional communication skills: possess a desire to understand the scientific requests of collaborators in depth, manage multiple continuous collaborations, and translate complex concepts and data interpretation into clear, actionable outputs for non-specialists. Desirable: Experience with LIMS, ELNs and data management. Experience in biological library screening, e.g. directed evolution, CRISPR screening, display technologies, deep mutational scanning. Experience with advanced sequencing techniques such as Hi-C, ChIP-Seq, SHAPE, nascent RNASeq. Experience in bioinformatics packages such as Nextflow, GATK, hifiasm. Experience with common programming languages such as Python, R, Unix. Experience with laboratory automation (e.g. Biomek i7) We offer the following salary and benefits: Salary: Competitive salary on offer Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electrical Car Scheme Why work for EIT: At the Ellison Institute, we believe a collaborative, inclusive team is key to our success. We are building a supportive environment where creative risks are encouraged, and everyone feels heard. Valuing emotional intelligence, empathy, respect, and resilience, we encourage people to be curious and to have a shared commitment to excellence. Join us and make an impact! Terms of Appointment: You must have the right to work permanently in the UK with a willingness to travel as necessary. You will live in, or within easy commuting distance of, Oxford. During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme.
Senior Scientist (Next-generation sequencing) - Generative Biology Institute
Ellison Institute, LLC Oxford, Oxfordshire
The Ellison Institute of Technology (EIT) tackles humanity's greatest challenges by turning science and technology into impactful global solutions. Focused on areas like health, food security, sustainable agriculture, climate change, clean energy, and robotics in an era of artificial intelligence. EIT blends groundbreaking research with practical applications to deliver lasting results. A cornerstone of EIT mission is its upcoming 300,000-square-foot research facility at the Oxford Science Park, set to open in 2027. This cutting-edge campus will feature advanced labs, an oncology and preventative care clinic, and collaborative spaces to strengthen its partnership with the University of Oxford. It will also host the Ellison Scholars, driving innovation for societal benefit. The Generative Biology Institute (GBI) at the Ellison Institute of Technology (EIT) aims to overcome two major challenges in making biology engineerable: 1) the ability to precisely synthesize entire genomes, and 2) understanding which DNA sequences will create biological systems that perform desired functions. Solving these challenges will unlock the potential of biology for transformative solutions in health, sustainability, agriculture, and more. GBI will house 30 groups and over 300 researchers, supported by cutting-edge facilities and sustained funding to address global challenges and advance biology engineering. EIT fosters a culture of collaboration, innovation, and resilience, valuing diverse expertise to drive sustainable solutions to humanity's enduring challenges. Job Summary: We are seeking a highly motivated scientist to join as a foundingmember of our next-generation sequencing team within a dynamic research environment. Overall, this team will empower fellow scientists to confidently take full advantage of next-generation sequencing technology in their research. This team will manage the walk-up and supervised usage of Illumina, Nanopore, PacBio & Elements sequencing machines, be assisted by a state-of-the-art automation platform, and have access to a high-performance cluster for bioinformatic analysis. The successful candidate will play a key role in supporting research across multiple groups and themes by providing expertise in delivering high-quality sequencing data and developing innovative workflows that support a diversity of experimental applications. You will collaborate closely with research groups to design and execute sequencing strategies tailored to novel and emerging scientific questions, and such contributions will be equitably acknowledged through authorship on relevant outputs. Key Responsibilities: To design and perform sequencing workflows using a range of platforms (Illumina, Oxford Nanopore, PacBio and Elements) or other high-throughput platforms, adapting protocols as needed to meet experimental requirements. To design and execute bespoke sequencing experiments, collaborating with research teams working across niche and novel synthetic, molecular & cell biology applications. To train, assist and feedback to other scientists who can or wish to utilise next-generation sequencing in a walk-up fashion. To analyse sequencing data using existing bioinformatics tools and pipelines, and bespoke solutions if necessary, delivering actionable insights to collaborating scientists. To continuously curate an expert understanding on the underlying technologies in the full sequencing workflow (Experiment - DNA extraction - library preparation - sequencing - analysis, and associated QC steps). To have a close working relationship with scientists from automation and bioinformatics teams. To contribute to the maintenance, calibration, and troubleshooting of sequencing instruments, ensuring maximal performance and data quality. To stay abreast of new sequencing technologies and methodologies, integrating improvements to enhance performance, throughput and cost-efficiency. Essential Knowledge, Skills and Experience: A PhD (or equivalent industry experience) in a relevant field, such as genomics, molecular biology, synthetic biology, cell biology, or computational biology. Hands-on experience with next-generation sequencing technologies (e.g., Illumina, Oxford Nanopore). Proven ability to develop, adapt, and troubleshoot sequencing workflows. Familiarity with basic bioinformatics tools for sequencing analysis and interpretation OR confident in multiple programming languages and coding/simple software development. A track record of working effectively in a collaborative, multi-disciplinary research environment. Exceptional communication skills: possess a desire to understand the scientific requests of collaborators in depth, manage multiple continuous collaborations, and translate complex concepts and data interpretation into clear, actionable outputs for non-specialists. Desirable: Experience with LIMS, ELNs and data management. Experience in biological library screening, e.g. directed evolution, CRISPR screening, display technologies, deep mutational scanning. Experience with advanced sequencing techniques such as Hi-C, ChIP-Seq, SHAPE, nascent RNASeq. Experience in bioinformatics packages such as Nextflow, GATK, hifiasm. Experience with common programming languages such as Python, R, Unix. Experience with laboratory automation (e.g. Biomek i7) We offer the following salary and benefits: Salary: Competitive salary on offer Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electrical Car Scheme Why work for EIT: At the Ellison Institute, we believe a collaborative, inclusive team is key to our success. We are building a supportive environment where creative risks are encouraged, and everyone feels heard. Valuing emotional intelligence, empathy, respect, and resilience, we encourage people to be curious and to have a shared commitment to excellence. Join us and make an impact! Terms of Appointment: You must have the right to work permanently in the UK with a willingness to travel as necessary. You will live in, or within easy commuting distance of, Oxford. During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme.
Sep 11, 2025
Full time
The Ellison Institute of Technology (EIT) tackles humanity's greatest challenges by turning science and technology into impactful global solutions. Focused on areas like health, food security, sustainable agriculture, climate change, clean energy, and robotics in an era of artificial intelligence. EIT blends groundbreaking research with practical applications to deliver lasting results. A cornerstone of EIT mission is its upcoming 300,000-square-foot research facility at the Oxford Science Park, set to open in 2027. This cutting-edge campus will feature advanced labs, an oncology and preventative care clinic, and collaborative spaces to strengthen its partnership with the University of Oxford. It will also host the Ellison Scholars, driving innovation for societal benefit. The Generative Biology Institute (GBI) at the Ellison Institute of Technology (EIT) aims to overcome two major challenges in making biology engineerable: 1) the ability to precisely synthesize entire genomes, and 2) understanding which DNA sequences will create biological systems that perform desired functions. Solving these challenges will unlock the potential of biology for transformative solutions in health, sustainability, agriculture, and more. GBI will house 30 groups and over 300 researchers, supported by cutting-edge facilities and sustained funding to address global challenges and advance biology engineering. EIT fosters a culture of collaboration, innovation, and resilience, valuing diverse expertise to drive sustainable solutions to humanity's enduring challenges. Job Summary: We are seeking a highly motivated scientist to join as a foundingmember of our next-generation sequencing team within a dynamic research environment. Overall, this team will empower fellow scientists to confidently take full advantage of next-generation sequencing technology in their research. This team will manage the walk-up and supervised usage of Illumina, Nanopore, PacBio & Elements sequencing machines, be assisted by a state-of-the-art automation platform, and have access to a high-performance cluster for bioinformatic analysis. The successful candidate will play a key role in supporting research across multiple groups and themes by providing expertise in delivering high-quality sequencing data and developing innovative workflows that support a diversity of experimental applications. You will collaborate closely with research groups to design and execute sequencing strategies tailored to novel and emerging scientific questions, and such contributions will be equitably acknowledged through authorship on relevant outputs. Key Responsibilities: To design and perform sequencing workflows using a range of platforms (Illumina, Oxford Nanopore, PacBio and Elements) or other high-throughput platforms, adapting protocols as needed to meet experimental requirements. To design and execute bespoke sequencing experiments, collaborating with research teams working across niche and novel synthetic, molecular & cell biology applications. To train, assist and feedback to other scientists who can or wish to utilise next-generation sequencing in a walk-up fashion. To analyse sequencing data using existing bioinformatics tools and pipelines, and bespoke solutions if necessary, delivering actionable insights to collaborating scientists. To continuously curate an expert understanding on the underlying technologies in the full sequencing workflow (Experiment - DNA extraction - library preparation - sequencing - analysis, and associated QC steps). To have a close working relationship with scientists from automation and bioinformatics teams. To contribute to the maintenance, calibration, and troubleshooting of sequencing instruments, ensuring maximal performance and data quality. To stay abreast of new sequencing technologies and methodologies, integrating improvements to enhance performance, throughput and cost-efficiency. Essential Knowledge, Skills and Experience: A PhD (or equivalent industry experience) in a relevant field, such as genomics, molecular biology, synthetic biology, cell biology, or computational biology. Hands-on experience with next-generation sequencing technologies (e.g., Illumina, Oxford Nanopore). Proven ability to develop, adapt, and troubleshoot sequencing workflows. Familiarity with basic bioinformatics tools for sequencing analysis and interpretation OR confident in multiple programming languages and coding/simple software development. A track record of working effectively in a collaborative, multi-disciplinary research environment. Exceptional communication skills: possess a desire to understand the scientific requests of collaborators in depth, manage multiple continuous collaborations, and translate complex concepts and data interpretation into clear, actionable outputs for non-specialists. Desirable: Experience with LIMS, ELNs and data management. Experience in biological library screening, e.g. directed evolution, CRISPR screening, display technologies, deep mutational scanning. Experience with advanced sequencing techniques such as Hi-C, ChIP-Seq, SHAPE, nascent RNASeq. Experience in bioinformatics packages such as Nextflow, GATK, hifiasm. Experience with common programming languages such as Python, R, Unix. Experience with laboratory automation (e.g. Biomek i7) We offer the following salary and benefits: Salary: Competitive salary on offer Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electrical Car Scheme Why work for EIT: At the Ellison Institute, we believe a collaborative, inclusive team is key to our success. We are building a supportive environment where creative risks are encouraged, and everyone feels heard. Valuing emotional intelligence, empathy, respect, and resilience, we encourage people to be curious and to have a shared commitment to excellence. Join us and make an impact! Terms of Appointment: You must have the right to work permanently in the UK with a willingness to travel as necessary. You will live in, or within easy commuting distance of, Oxford. During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme.
Lonza
Senior Bioinformatics Engineer - Pipeline Automation & Tool Development
Lonza Dursley, Gloucestershire
Senior Bioinformatics Engineer - Pipeline Automation & Tool Development Location: Cambridge Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that's the kind of work we want to be part of. The Senior Bioinformatics Engineer - Pipeline Automation & Tool Development will be responsible for developing efficient and high quality bioinformatic pipelines and data science software supporting the design, data processing, analysis, and reporting across Lonza R&D departments. They will be placed in the Bioinformatics & Data Science group and closely work with multi-disciplinary teams of bioinformaticians, lab scientists, biochemists and bioprocess engineers. The Senior Bioinformatics Engineer - Pipeline Automation & Tool Development will further drive and implement innovative solutions enhancing Lonza's capabilities in data science and statistics, with the goal to improve biomanufacturing of Biologics molecules. The role is also expected to manage collaborations and act as mentor for more junior team members. What you'll do: Develop and maintain bioinformatic pipelines to facilitate complex data analysis and integration. Supports onboarding and development of data analysis tools used by multidisciplinary teams across Lonza. Drives digital innovation in biomanufacturing by enhancing data science, bioinformatics and statistical capabilities. Manages internal and external collaborations with academic and commercial partners. Leads, mentors and trains junior team members. What we're looking for: PhD with at least 2 years of industry experience or MSc with 5 or more years of relevant experience in bioinformatics, computational biology, data science or a related field. Hands-on experience in developing and implementing multiple Nextflow pipelines in a production system. Excellent knowledge of Docker, git, the UNIX command line, R (or python) and unit/pipeline testing frameworks. Minimum 2 years work experience in developing and rolling out GUI-based bioinformatic tools facilitating experimental design and analyses. Proven ability to communicate complex bioinformatic concepts to stakeholders and multidisciplinary teams. General expertise in analyzing and interpreting omics and other biological data sets using statistical and visualization approaches. Good organizational skills, including time management, ability to set priorities and adhere to deadlines. Strong attention to detail and problem solving skills. Every day, Lonza's products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically. People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference. Lonza is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a qualified individual with disability, protected veteran status, or any other characteristic protected by law.
Jul 14, 2025
Full time
Senior Bioinformatics Engineer - Pipeline Automation & Tool Development Location: Cambridge Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that's the kind of work we want to be part of. The Senior Bioinformatics Engineer - Pipeline Automation & Tool Development will be responsible for developing efficient and high quality bioinformatic pipelines and data science software supporting the design, data processing, analysis, and reporting across Lonza R&D departments. They will be placed in the Bioinformatics & Data Science group and closely work with multi-disciplinary teams of bioinformaticians, lab scientists, biochemists and bioprocess engineers. The Senior Bioinformatics Engineer - Pipeline Automation & Tool Development will further drive and implement innovative solutions enhancing Lonza's capabilities in data science and statistics, with the goal to improve biomanufacturing of Biologics molecules. The role is also expected to manage collaborations and act as mentor for more junior team members. What you'll do: Develop and maintain bioinformatic pipelines to facilitate complex data analysis and integration. Supports onboarding and development of data analysis tools used by multidisciplinary teams across Lonza. Drives digital innovation in biomanufacturing by enhancing data science, bioinformatics and statistical capabilities. Manages internal and external collaborations with academic and commercial partners. Leads, mentors and trains junior team members. What we're looking for: PhD with at least 2 years of industry experience or MSc with 5 or more years of relevant experience in bioinformatics, computational biology, data science or a related field. Hands-on experience in developing and implementing multiple Nextflow pipelines in a production system. Excellent knowledge of Docker, git, the UNIX command line, R (or python) and unit/pipeline testing frameworks. Minimum 2 years work experience in developing and rolling out GUI-based bioinformatic tools facilitating experimental design and analyses. Proven ability to communicate complex bioinformatic concepts to stakeholders and multidisciplinary teams. General expertise in analyzing and interpreting omics and other biological data sets using statistical and visualization approaches. Good organizational skills, including time management, ability to set priorities and adhere to deadlines. Strong attention to detail and problem solving skills. Every day, Lonza's products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically. People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference. Lonza is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a qualified individual with disability, protected veteran status, or any other characteristic protected by law.

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