27 jobs found

We are looking for a motivated and talented postdoctoral-level researcher with experience in executable modelling to join a cutting-edge project developing Digital Twins for rare diseases. This is a unique opportunity to work at the intersection of systems biology, AI, and translational research, and to contribute to open science through the Chan Zuckerberg Initiative. Your group Petsalaki Group, in collaboration with Open Targets and BioModels teams. The project Digital Twins are virtual representations of patients that simulate disease progression and treatment response. Rare diseases pose a unique challenge due to limited patient data-especially at the single-cell level-making traditional modelling approaches difficult. This project tackles that challenge by integrating multi-omics and clinical data using hybrid models combining mechanistic, GenAI, and machine learning approaches. You'll contribute to building disease-specific Digital Twins using large-scale single-cell multi-omics datasets, mechanistic simulations, and predictive AI models. Your work will help unlock new insights into disease mechanisms and inform potential treatments, diagnostics, and drug repurposing opportunities. Your role You will develop and apply methods to transform omics data into networks and executable models, collaborating closely with experts across the Petsalaki and Sheriff groups, Open Targets, EMBL-EBI, and the wider rare disease and biocuration community. You will be primarily supervised by the Petsalaki group (Whole cell sigalling) and the Sheriff team (Biomodels). The Petsalaki group develops data driven network inference and modelling approaches from large omics datasets and the Sheriff team leads the development of innovative modelling approaches and maintenance of the Biomodels database. Key responsibilities include: - Generation of phenotype-specific networks from bulk-RNAseq and scRNAseq data from rare disease patients - Building executable models (Boolean, ODE, agent-based or others) from omics data - Collaborating closely with data curators, multi-omics data scientists and AI engineers to integrate and enrich disease datasets, and test and validate models - Applying hybrid modelling approaches to limited data scenarios - Enabling multi-scale and cross-disease modelling for hypothesis generation and therapy discovery - Ensure FAIR principles in your outputs and contribute to the open source community by sharing models (where possible) in BioModels and other repositories - Generation of synthetic data to represent rare disease patients that can be shared You have - A PhD in bioinformatics, physics, or a related data-intensive field - Proficiency in Python (or R), version control, and clean code practices - Experience with omics data analysis and integration - Hands-on expertise in developing and fitting executable models - Strong communication and teamwork skills You may also have - Network inference and analysis experienc - Machine learning experience - Track record of completed research projects (e.g., publications, tools) Benefits and Contract Information - Financial incentives: depending on circumstances, monthly family/marriage allowance of £272, monthly child allowance of £328 per child. Generous stipend reviewed yearly, pension scheme, death benefit, long-term care, accident-at-work and unemployment insurances - Hybrid working arrangements - Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover) - Generous time off: 30 days annual leave per year, in addition to eight bank holidays - Relocation package - Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely) - Family benefits: On-site nursery, child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances - Contract duration: This position is a 2 year fixed term grant limited contract - Salary: Year 1 Stipend at rate of £3,307 (Total package will be dependant on family circumstances) - International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants. - Diversity and inclusion: At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ and individuals from all nationalities. - Job location: This role is based in Hinxton, near Cambridge, UK. You will be required to relocate if you are based overseas and you will receive a generous relocation package to support you. - DORA - EMBL is a signatory of DORA and is committed to hiring and training outstanding research, service, and administrative personnel. Year 1 Stipend - £3,307 per month after tax

Postdoc in Bayesian machine learning, AstraZeneca, Cambridge, UK Mar 29, 2018 PREDICTING DRUG TOXICITY WITH BAYESIAN MACHINE LEARNING MODELS We're currently looking for talented scientists to join our innovative academic-style Postdoc. From our centre in Cambridge, UK you'll be in a global pharmaceutical environment, contributing to live projects right from the start. You'll take part in a comprehensive training programme, including a focus on drug discovery and development, given access to our existing Postdoctoral research, and encouraged to pursue your own independent research. It's a newly expanding programme spanning a range of therapeutic areas across a wide range of disciplines. What's more, you'll have the support of a leading academic advisor, who'll provide you with the guidance and knowledge you need to develop your career. You will be part of the Quantitative Biology group and develop comprehensive Bayesian machine learning models for predicting drug toxicity in liver, heart, and other organs. This includes predicting the mechanism as well as the probability of toxicity by incorporating scientific knowledge into the prediction problem, such as known causal relationships and known toxicity mechanisms. Bayesian models will be used to account for uncertainty in the inputs and propagate this uncertainty into the predictions. In addition, you will promote the use of Bayesian methods across safety pharmacology and biology more generally. You are also expected to present your findings at key conferences and in leading publications This project is in collaboration with Prof. Andrew Gelman at Columbia University, and Dr Stanley Lazic at AstraZeneca. Education and Experience Required: - PhD in Statistics, Computer Science, Data Science, or similar - Excellent knowledge of either R or Python (ideally both) - Knowledge of Bayesian statistics - Knowledge of modern Bayesian software such as Stan and PyMC3 - Knowledge of (or an interest in) life sciences This is a 3 year programme. 2 years will be a Fixed Term Contract, with a 1 year extension which will be merit based. The role will be based at Cambridge, UK with a competitive salary on offer. To apply for this position, please follow the link below:

Postdoctoral Researcher (Foraminifera Geochemist) Postdoc Researcher Scroll down to read more: Rehemat Job title: Postdoctoral Researcher - Foraminifera Geochemist What does a Foraminifera Geochemist do? I am a hybrid micropalaeontologist and geochemist. A micropalaeontologist studies microscopic fossils, and a geochemist analyses the chemistry of geological materials. I use the chemistry of fossil species of foraminifera, a type of plankton with a calcium carbonate skeleton, to understand more about their ecologies and climate millions of years ago (palaeoclimatology). Different chemical elements can help me understand how hot the oceans were, whether some species of plankton lived closer to the surface of the ocean or further down in the water column, and even how much ice there was on land! I wash sediment samples, identify the plankton hiding inside, then analyse them for their chemistry and try to understand the data they produce. What formal qualifications and previous work experience did you need to get your job? When I was a teenager I did some work experience at the Natural History Museum, London and The Royal Geographical Society. Having had a super positive introduction to Earth Sciences through these experiences, I decided to do an undergraduate MSci degree in Geoscience at Royal Holloway (University of London). During my undergraduate degree I did several internships. I interned at a structural geology company, biostratigraphy company and a summer research internship focused around foraminifera and palaeoclimatology working with a PhD student in Kiel, Germany. I also volunteered at the Natural History Museum throughout the final years of my undergraduate degree. These last two experiences made me realise I could combine my love of geochemistry and ocean sciences, and I subsequently decided to do a PhD at University College London. What other skills or characteristics do you need in your job? Always be curious Always be persistent Understand how to communicate your science to non-specialists in an enthusiastic way Have good attention to detail for taxonomy Know the importance of collaboration and networking. You never know when your mass spectrometer will break and you will need to contact another lab to use their instrument! What sort of organisation do you work for? Where else could you work as a Foraminifera Geochemist? I work at a university, but those with my background can also work in many different sectors, including the oil industry (as a biostratigrapher, using foraminfera to date rock formations), analytical instrument companies, science policy and publishers. Science communication is also popular, but this is definitely applicable as a career path across geological facets! Working in the third sector (i.e. with charities and NGOs) within Trusts and Foundations/Major Donor Fundraising is also possible, because all researchers have the ability to network, collaborate, project manage, build relationships with others and write grant applications concisely. What do you enjoy about your job? Foraminifera are beautiful and each time I have microscope work to do it is a joy to see them. I enjoy being able to talk with young people about what I do. It's really rewarding to inspire the generation to go into STEM and sometimes even helps me figure out what my data mean! I like how no two days are the same. Sometimes I'm doing labwork, sometimes I am writing and sometimes I am reading about all the new and exciting science that is going on in the field. Whilst the dynamic-ness of being a researcher can sometimes be challenging in terms of work/life balance, my lab group are really supportive and I'm so lucky to be working with them. What opportunities do you have to develop your skills in your job? In my postdoc and PhD, I went to summer schools and workshops focused around Earth and ocean sciences in some really cool places, including Israel and Italy. I also went to international conferences to present my data, and regularly did outreach presentations to young people. I also had the opportunity to attend workshops focused around science policy and diversity and inclusion in the geosciences. It's definitely important to go to a variety of professional development courses, because if researchers decide academia is not for them at any point in their career, they have evidence that they have some training for other sectors. What advice or extra information do you wish you'd had before starting this career? Writing is a big part of being an academic, and it can be really challenging. But the first draft of anything will never be perfect, and words down on paper is much better than no words at all! No two days are the same when you are a geoscientist. Even if you don't pass an exam early on during undergrad, this doesn't define who you are. There are always more opportunities to do better next time. When you say you're a geologist, sometimes people will be surprised by this. But it's not weird to like rocks and fossils. Geologists and ocean scientists study some of the oldest things on the Earth, go to some absolutely amazing places (for work!), and unravel the stories of the world around them.

Hours per week 37 Project Title Computational Modelling of Epigenetic Dynamics Expected/Ideal Start Date 01 Oct 2025 Months Duration 36 Job Description Main Purpose of the Job Applications are invited for a Postdoctoral Researcher to join the group of Prof Martin Howard in the Department of Computational and Systems Biology at the John Innes Centre, Norwich, UK. The main purpose of the position is to develop computational models of epigenetic dynamics in the Polycomb system, collaborating with the experimental group of Prof Rob Klose (Oxford). Key Relationships Other members of the Howard group, other groups within Computational and Systems Biology at JIC, and other external experimental groups, particularly that of Prof. Rob Klose in the Dept of Biochemistry, Oxford University. Main Activities & Responsibilities Percentage Identify, plan, carry out and modify modelling to meet the objectives of the project 50 Prepare results, reports and manuscripts for publication in leading scientific journals and other relevant media 20 Disseminate research findings through presentations to various audiences at internal, national and international meetings 10 Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements 5 Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence 5 Continually strive for excellence, seeking out and acting on feedback and relevant learning and development opportunities 5 As agreed with the line manager, any other duties commensurate with the nature of the post, for example, contributing to the work of Institute committees 5 Person Profile Education & Qualifications Requirement Importance PhD (full award or expected within 6 months) in Theoretical Physics/Bio-Mathematics/Computational Biology Essential BSc or equivalent in a relevant scientific field Essential Specialist Knowledge & Skills Requirement Importance Ability to apply techniques from theoretical physics/applied mathematics to biological problems Essential Strong interest in biological problems Essential Computer programming experience (e.g. use of computational tools such as MatLab) Desirable Requirement Importance Demonstrable scientific success, with track-record of publications and presentations Essential Prior experience in biological modelling Desirable Interpersonal & Communication Skills Requirement Importance Self-motivated, creative and intellectually independent Essential Good verbal and written communication skills, facilitating interaction with experimentalists Essential Ability to collaborate with internal and external stakeholders Essential Excellent time management and organisational skills Essential Good interpersonal skills, with the ability to work well as part of a team Essential Additional Requirements Requirement Importance Available to travel to international meetings and for short visits to collaborating laboratories Essential Willingness to work outside standard working hours when required Essential Attention to detail Essential Promotes equality and values diversity Essential Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work Essential Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute Essential Who We Are The John Innes Centre is an independent, international centre of excellence in plant and microbial genetics, carrying out fundamental and strategic research, to train scientists and making our findings available to society. Our research makes use of a wide range of disciplines in the biological and chemical sciences including; cell biology, biochemistry, chemistry, genetics and molecular biology. We pride ourselves on being a welcoming and inclusive working environment for all. We have a diverse and multicultural scientific community and thrive on our European and international links, appointing staff from across the world. Any candidate who would like further information on current or anticipated immigration requirements can contact the HR Team on (0) or . We are proud to hold a prestigious Athena SWAN Gold award , recognising the impact of our work in promoting gender equality in science. We are also a proud member of the Stonewall Diversity Champion's programme , a founding signatory of the Tecnician Commitment and, as a Disability Confident employer, guarantee to offer an interview to all disabled applicants who meet the essential criteria for the post. The John Innes Centre is a registered charity (No. 223852), limited by guarantee (registered in England No. 511709). Department Computational and Systems Biology The Department of Computational and Systems Biology conducts world-leading research across a broad range of the biological sciences, with a special focus on spatial problems in plant and microbial research. Particular strengths of the department include mathematical and statistical modelling of the physical mechanisms underlying biological pattern formation, transport dynamics, epigenetic processes, size control, biomechanics and gene network dynamics. In addition, the department has strong bioinformatics that underpins the research of the institute through training, software development and statistical analysis. While much of the research is carried out in close collaboration with world-leading experimental groups within the John Innes Centre, we also have strong international collaborations with experimentalists and theoreticians worldwide. The Howard group combines simple, predictive mathematical and biophysical modelling with long-lasting experimental collaborations to dissect biological mechanisms too complex to unravel by experiments alone. In many cases we are able to rationalise complex biological dynamics into simple underlying mechanisms, with few components and interactions. Our approach is highly interdisciplinary and relies heavily on the techniques of statistical physics and applied mathematics, as well as on close collaboration with experimental groups. This truly interdisciplinary approach allows us to get to the heart of biological mechanisms more speedily. At present there are two main foci in the group: probing how epigenetic memory states are set up and then stably maintained, and understanding patterning dynamics in sub-cellular biological systems. For epigenetics, we work on both histone modification memory systems, including the Polycomb system, as well as on DNA methylation. For patterning, the main application at present is to the dynamics of crossover positioning in meiosis. The group collaborates with a wide range of experimentalists in systems ranging from plants to mammalian stem cells. Currently there are three Postdoctoral Researchers in the group. Postdoctoral Researcher Salary: £36,720 - £39,750 per annum depending on qualifications and experience. Contract: 36 months, full-time Location: John Innes Centre, Norwich, UK. Closing date: 2 August 2025 Reference: An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology. About the John Innes Centre: The John Innes Centre is an independent, international centre of excellence in plant and microbial sciences. We nurture a creative, curiosity-led approach to answering fundamental questions in bioscience, and translate that knowledge into societal benefits. Our strategic vision, Healthy Plants, Healthy People, Healthy Planet , sets out our ambitious long-term goals for the game changing impact of our science globally. Our employees enjoy access to state-of-the-art technology and a diverse range of specialist training opportunities, including support for leadership and management. Click here to find out more about working at the John Innes Centre. About the Howard Group: The Howard group combines simple, predictive mathematical and biophysical modelling with long-lasting experimental collaborations to dissect biological mechanisms too complex to unravel by experiments alone. In many cases we are able to rationalise complex biological dynamics into simple underlying mechanisms, with few components and interactions. Our approach is highly interdisciplinary and relies heavily on the techniques of statistical physics and applied mathematics, as well as on close collaboration with experimental groups. At present there are two main research areas in the group: probing how epigenetic memory states are set up and then stably maintained, and understanding patterning dynamics in sub-cellular biological systems. For epigenetics, we work on both histone modification memory systems, particularly the Polycomb silencing system, as well as on DNA methylation. For patterning, the main application at present is to the dynamics of crossover positioning in meiosis. The group regularly publishes in the most prominent multidisciplinary journals, with recent papers in Nature, Science, Cell Systems, eLife, Molecular Cell and PNAS. Several previous members of the Howard group now hold independent faculty positions of their own, including in Warwick, Glasgow, Sydney, Amsterdam and Munich. The role: . click apply for full job details

View Vacancy MRC Postdoctoral Research Scientist LMS 2663 Open Date 11/07/2025, 10:00 Close Date 12/08/2025, 23:55 Research Institute MRC Laboratory of Medical Sciences Research Institute / Unit Information The LMS is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation , the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus (W12). The LMS aims to deliver transdisciplinary team science, in synergistic interaction with Imperial College and the wider national research environment. Part of achieving this, is to recruit new talent and support postdoctoral scientists to become world leaders in their area of science. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at Band MRC - 4 Location London £41,344 plus London allowances £5,385 per annum Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two Contract Type Fixed Term Job Type Science Full Time / Part Time Full Time 2 years (with a possibility of extension) Job Description Overall purpose: Understanding how the right cell types form in the right position and proportion during embryonic development represents one of the most important open questions in developmental biology. The Development & Transcriptional Control Group is tackling this challenge by investigating how cell identity is established and how it shapes the mammalian body. Our multidisciplinary approach integrates mouse developmental genetics, stem cell-based models of development, and genome engineering. These systems support quantitative and mechanistic studies, allowing us to address how cis-regulatory elements function and their effect on the body plan (Amblard et al., Dev Cell , 2025). We're seeking a highly motivatedpostdoctoral scientist to develop new tools and methodologies to uncover the gene regulatory principles of mammalian development. The role offers opportunities to pursue independent research ideas within the lab's core focus, with strong support for career development and scientific training. Main duties / key responsibilities: Design and conduct high-quality, independent research aligned with project aims Critically analyse, interpret, and present experimental data with rigor and reproducibility Stay up to date with relevant literature and integrate new findings and techniques into your research Develop and refine experimental methods and protocols as needed Participate fully in lab meetings, presenting research progress and contributing to discussions Provide support and mentorship to students and junior researchers as required Take part in journal clubs and internal seminar programmes Present findings at national and international conferences (where appropriate) Contribute to day-to-day lab operations and shared responsibilities Collaborate effectively within the group and with external collaborators Additional information: Applicants should have a PhD in a relevant discipline, with a strong commitment to scientific excellence and teamwork. This is an MRC Postdoctoral Scientist position to support post-doctoral training and help establish successful research scientists in their chosen field. During the fellowship tenure we are committed to provide mentorship for career development and improvement of communication skills. We also offer a highly attractive benefits package including competitive salary and salary pension scheme. Person Specification Education / Qualifications / Training required (will be assessed from the application): Essential: PhD (or equivalent experience) in a relevant biology field (e.g., molecular biology, cell biology, biochemistry, developmental biology, genetics) Previous work experience required (will be assessed from the application and at the interview ): Essential: Significant practical expertise in molecular biology techniques such as PCR, cloning, CRISPR/Cas9 Experience in design and/or generation and validation of new mammalian cell lines (eg. knockouts, reporters, epitope-tagging etc) Significant practical expertise in mammalian cell culture techniques Desirable: Experience working with embryonic stem cells as 2D/3D in vitro models of development, or mouse embryos or similar animal model organisms Experience in modifying embryonic stem cells using genome engineering approaches Experience in generating and/or analysing and integrating different high throughput sequencing data to study cell identity or gene regulation, such as ChIP-seq, Cut&Run, RNA-seq, ATAC-seq Knowledge and experience (will be assessed from the application and at the interview): Essential: Strong conceptual background and interest in at least one of the following: gene regulation in development, embryonic development, or stem cell models of development Excellent written communication skills in English Desirable: At least one first-author publication in a peer-reviewed international journal or available as a preprint Experience presenting scientific data at national or international scientific conferences Personal Skills / Behaviours / Qualities (will be assessed at interview) : Essential: Enthusiastic and collaborative team player Ability to conduct research independently, including the design, execution, and analysis of experiments Eagerness to learn and acquire new skills, troubleshoot experiments, and apply creative approaches to scientific questions Willingness to work flexible hours as needed by the project, and to travel for conferences or research collaborations Excellent verbal communication skills in English Further Information Applicants must submit the following to be considered: A CVA brief cover letter addressing: Motivation for joining the team How the applicant meets the selection criteria Names and contact details of two scientific referees Please note : Incomplete applications will not be considered. This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successfulapplicant is likely to be eligible to apply. Immigrationcosts for the applicant (100% visa and 100% Health Surcharge) and immediate dependents (100% visa and 50% health surcharge when applying with the main applicant) can be reclaimed from LMS after taking up the post (terms and conditions apply). Please note that applications may be reviewed by both LMS and Imperial staff The MRC is a unique working environment where scientific researchers and professional support staff can actively partake in world class innovation and collaboration opportunities and their skills and knowledge through accessing a wide catalogue of training & development, including professional registration with the Science Council. In addition, MRC (part of UKRI) provides its community of employees access to a whole host of useful benefits, including a defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We warmly invite people from diverse backgrounds and heritage, including people who identify as having a disability, to apply for a role that excites them. As "Disability Confident" employers, we guarantee to interview all applicants who have disclosed they have a disability and who meet the minimum criteria for the vacancy. UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs. We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check. The role holder will be required to have the appropriate level of security screening/vetting required for the role. UKRI reserves the right to run or re-run security clearance as required during the course of employment. Copyright 2015. Medical Research Council

View Vacancy MRC Postdoctoral Research Scientist LMS 2662 Open Date 11/07/2025, 10:00 Close Date 12/08/2025, 23:55 Research Institute MRC Laboratory of Medical Sciences Research Institute / Unit Information The LMS is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation , the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus (W12). The LMS aims to deliver transdisciplinary team science, in synergistic interaction with Imperial College and the wider national research environment. Part of achieving this, is to recruit new talent and support postdoctoral scientists to become world leaders in their area of science. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at Band MRC - 4 Location London £41,344 plus London allowances £5,385 per annum Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two Contract Type Fixed Term Job Type Science Full Time / Part Time Full Time 2 years (with a possibility of extension) Job Description Overall purpose: Research Programme The Reprogramming and Chromatin group led by Prof Petra Hajkova investigates molecular processes that underlie global erasure of epigenetic information. As in vitro cellular reprogramming systems are notoriously inefficient and heterogeneous in outcome, we focus on the epigenetic reprogramming events that occur naturally in vivo during mouse development (in the mouse zygote and in the developing mouse germ cells) ( ). We have a particular interest in deciphering the mechanisms underlying the waves of global DNA demethylation (Amouroux et al, 2016, Hill et al, Nature 2018; Huang et al, Nature 2021) and the changes in chromatin structure that accompanies this process. Purpose of Post The focus of this project is to investigate molecular mechanisms underpinning zygotic and germline DNA demethylation, the mechanistic links to DNA repair and the functional relationship to the progression through the germline cycle. The ideal candidate will be expected to carry out research within the focus area of the Reprogramming and Chromatin Group; undertake project management and be involved in the supervision of PhD students in the laboratory. In addition, he/she will be expected to submit publications to refereed journals and to attract external research funding. Main duties / key responsibilities: To take initiatives in the planning of research To direct the work of small research teams To identify and develop suitable techniques, and apparatus, for the collection and analysis of data To conduct data analysis To ensure the validity and reliability of data at all times To maintain accurate and complete records of all findings To write reports for submission to research sponsors To present findings to colleagues and at conferences To submit publications to refereed journals To provide guidance to staff and students To attend relevant workshops and conferences as necessary To develop contacts and research collaborations within the College and the wider community To promote the reputation of the Group, the Department and the Institute To provide guidance to PhD Students Contribute to bids for research grants To conduct and plan own scientific work with appropriate supervision To maintain highly organised and accurate record of experimental work To actively participate in the research programme of the Group and Unit To publish in high quality journals and to present data at national and international meetings To participate in Group/Unit research meetings and internal seminars Willingness to work out of normal working hours (including weekends) if the requirements of the project demand To collaborate with other allied scientists within Institute and elsewhere in London and abroad, as appropriate To contribute to the smooth running of the Group's/Unit's laboratories and, facilities with other scientists, clinicians, technicians and students within the laboratories To assist in the supervision of undergraduate and postgraduate research students and research assistants as required To comply with the Institute safety practices and to attend courses on safety when appropriate Any other duties as may be deemed reasonable by Head of group Working relationships: The post-holder will report directly to the head of the group, Professor Petra Hajkova. Additional information: This post is an MRC Postdoctoral Scientist to support post-doctoral training and help establish successful research scientists in their chosen field. During the fellowship tenure we are committed to provide mentorship for career development and improvement of communication skills. Person Specification Education / Qualifications / Training required (will be assessed from the application): Essential: PhD degree (or equivalent experience) in a biological or related discipline Desirable: UK Home Office personal licence (PIL) for work with rodents Previous work experience required (will be assessed from the application and at the interview): Essential: Proven experience in the field of epigenetics and chromatin Experience with isolation, manipulation and culture of mouse oocytes and early mouse preimplantation embryos Extensive experience with cell lines and mouse primary cell culture techniques Experience with culture of mouse pluripotent stem cells Knowledge of relevant biochemical and molecular biology research methods and statistical procedures Good written communication skills in English Desirable: Experience with derivation of mouse embryonic stem cells Experience with NGS approaches to investigate epigenome Personal skills / Behaviours / Qualities (will be assessed at the interview): Essential: Evidence of organisational ability Good verbal communication skills in English and the ability to work effectively with researchers ranging from postgraduate students to professorial level Ability to work both independently and as part of a team IT literate and familiar with basic methods for sequence and image analysis Desirable: A highly committed individual with proactive and flexible attitude to work The ability and willingness to learn new concepts and technologies rapidly The ability to work under pressure in the competitive field Further Information Pleaseupload your CV, the names and contact details of two scientific references along with a covering letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Applications without a cover letter will not be considered. Please quote reference number LMS 2662. This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successfulapplicant is likely to be eligible to apply. Immigrationcosts for the applicant (100% visa and 100% Health Surcharge) and immediate dependents (100% visa and 50% health surcharge when applying with the main applicant) can be reclaimed from LMS after taking up the post (terms and conditions apply). Please note that applications may be reviewed by both LMS and Imperial staff The MRC is a unique working environment where scientific researchers and professional support staff can actively partake in world class innovation and collaboration opportunities and their skills and knowledge through accessing a wide catalogue of training & development, including professional registration with the Science Council. In addition, MRC (part of UKRI) provides its community of employees access to a whole host of useful benefits, including a defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We warmly invite people from diverse backgrounds and heritage, including people who identify as having a disability, to apply for a role that excites them. As "Disability Confident" employers, we guarantee to interview all applicants who have disclosed they have a disability and who meet the minimum criteria for the vacancy. . click apply for full job details

Rebecca is a Research Scientist working at Natural Resources Canada /Geological Survey of Canada. She did an MSci Geology with study in North America at the University of Bristol followed by a Ph.D. in Geophysics (Seismology) at the University of Leeds. Can you give a brief description of what the company/employer does and how your role fits in? The Geological Survey of Canada (GSC) is the national organization for geoscientific information and research. Our work supports exploration and decision-making in the mining and energy sectors as well as national sovereignty, hazards risk management and more. I work in the Critical Minerals Geoscience and Data division, as well as the Induced Seismicity Research division. My research focuses on using geophysics (seismic, fiber optic technology) to identify structural controls for critical minerals in Canada, as well as using remote sensing satellite techniques to identify mineral systems. In addition to this, I am involved in projects relating to the causes and consequences of natural and induced seismicity from resource development projects including oil and gas, water disposal, geothermal and CCUS. As a research scientist, I am responsible for the development of research ideas, project oversight (including planning, procurement and financial elements), fieldwork planning and execution, data analysis and dissemination, interactions with external parties including private companies and First Nation Peoples and navigating both the government and academic systems (e.g. publishing, funding etc.). What does a typical day in your working life look like? My days are extremely varied - I could be planning research or fieldwork, analyzing data, in the field or disseminating results at a conference or in a written publication to the public or colleagues. For example, this week I have attended several weekly development meetings with different students and colleagues, written a job advertisement for a student hire, attended a 2 day workshop (online) relating to geothermal processes where I was part of a group presentation, done some python coding to obtain magnitudes of several earthquake swarms, done paperwork associated with the procurement of several pieces of field equipment, and planned a reconnaissance field trip to my field site in September. What was your pathway to what you do for your job now? Prior to joining the Geological Survey of Canada, I was a Research/Postdoctoral Associate at the University of Calgary () with research focused in induced and microsiesmicity as a result of resource development in western Canada. This included using detailed temporal and spatial analysis of seismicity, ambient seismic noise and new technologies including fiber optics, to better understand how fractures grow and develop; how highly pressurized fluids move through developing fracture networks; and in the identification and progression of slow slip events to better understand the continuum from aseismic to seismic slip. From I was a Profesor Visitante at the Observatorio Vulcanologico y Sismologico de Costa Rica, undertaking real time monitoring of tectonic and volcanic seismicity in Costa Rica and Central America. I obtained my PhD in Geophysics from the University of Leeds, UK (2015) with focus in using seismicity as a forecasting tool for volcanic eruptions, and hold a Masters and Undergraduate degree in Geology from the University of Bristol, UK (2011). What advice would you give to someone interested in pursuing a career like yours? Take every opportunity you can, even if it doesn't seem like anything will come out of it. Try and meet as many people as possible (attend guest lectures, conferences if you can, reach out via email if possible). Don't be scared to apply for jobs/positions where you don't meet 100% of the criteria - you never know what they are looking for and usually job postings are an absolute wish list that no candidate is ever likely to have!

Postdoctoral Research Associate/Assistant in Biochemistry Oban Full Time Job Details You will play a key role in advancing algal biotechnology by generating high-quality empirical datasets on the metabolic composition and activity of NERC-UKRI CCAP algal strains. The successful candidate will contribute to expanding the biotechnological potential of these strains, particularly for applications in the agri- and aquaculture sectors, while enhancing SAMS' research capacity in metabolomics and natural products. The role will focus on three core activities: overseeing untargeted biochemical phenotype screening across the CCAP collection, conducting full-trait characterisation of key sector-relevant strains within CCAP, and optimising bioassays to identify and quantify bioactivity of selected strains. This post is central to increasing the biotechnological value of the CCAP holdings and strengthening SAMS' research profile in this growing field. This work will be part of the Natural Products BioHUB project that we have in partnership with Swansea University (lead partner) and CABI. See project details here: You will work under the guidance of Lecturer in Algal Biotechnology/CCAP Manager and Associate Professor of Physiological Ecology. Ideally, we are looking for the successful candidate to start no later than 1st October 2025. Requirements We are seeking a post-doctoral researcher with a PhD in Phycology, Algal Biotechnology, or Biochemistry, ideally with a strong biochemistry focus. The ideal candidate will have experience in phycology/algal biotechnology involving either macroalgae and/or microalgae, and a proven ability to work effectively within interdisciplinary teams. A solid foundation in experimental design and method development in analytical biochemistry and biology is essential. The successful applicant will demonstrate strong written and verbal communication skills to effectively convey scientific findings. Experience with analytical techniques such as GC-MS and HPLC is highly desirable and will be considered a significant advantage. Contact Information Scottish Association for Marine Science SAMS We would love to hear from you. If you have queries on the job and would like to talk these through before applying, please email these through, in the first instance, to Dr Michael Ross - Applications must include CV and Cover Letter and should be sent electronically to quoting Job Ref. 'D05/25.MR' in the subject heading. Closing date for applications is 27th July 2025 - Interviews to be held shortly thereafter. Please note, we are unfortunately unable to provide visa sponsorship for this position. Full details, and guidance on applying, can be found here: Post Date: 7/6/2025 9:47:29 AM Closing Date: 7/27/:00:00 AM Share this job About this company SAMS is Scotland's largest independent marine research organisation delivering innovative, world-class marine science solutions to developing a sustainable relationship with the marine environment. This is done through research, education, services to business, and public engagement. SAMS has research expertise in areas including Arctic seas, marine renewable energy, people and the sea, and dynamic oceans. SAMS operates the modern and well-equipped Scottish Marine Institute at the scenic Dunstaffnage Peninsula near Oban, Argyll, and currently employs over 160 staff - including physical oceanographers, hydrographers, marine geologists, biogeochemists, microbial and molecular biologists, ecologists, social scientists, and modellers. About this company SAMS is Scotland's largest independent marine research organisation delivering innovative, world-class marine science solutions to developing a sustainable relationship with the marine environment. This is done through research, education, services to business, and public engagement. SAMS has research expertise in areas including Arctic seas, marine renewable energy, people and the sea, and dynamic oceans. SAMS operates the modern and well-equipped Scottish Marine Institute at the scenic Dunstaffnage Peninsula near Oban, Argyll, and currently employs over 160 staff - including physical oceanographers, hydrographers, marine geologists, biogeochemists, microbial and molecular biologists, ecologists, social scientists, and modellers. Read more