191 jobs found

Job description Site Name: London The Stanley Building Posted Date: Jun At GSK we see a world in which advanced applications of Machine Learning and AI will allow us to develop novel therapies to existing diseases and to quickly respond to emerging or changing diseases with personalized drugs, driving better outcomes at reduced cost with fewer side effects. It is an ambitious vision that will require the development of products and solutions at the cutting edge of Machine Learning and AI. If that excites you, we'd love to chat. We're looking for an AI/ML Engineer to help us make this vision a reality. Competitive candidates are outstanding engineers with a track record in developing SOTA deep learning models for solving challenging real world scientific problems and production grade AI-powered software solutions. Our team focuses on the discovery of preclinical digital biomarkers that translate robustly to clinical outcomes. An important outcome of our work is that, while enabling deeper insights into the effects and mechanisms of action of treatments, importantly, it also helps to advance the 3Rs framework, a set of principles that guide the ethical and humane use of animals in scientific research. In this role you will Convert vaguely described biological/drug discovery challenges into well-defined machine learning problems, particularly in the computer vision domain (both images and video). Execute and deliver full AI/ML driven solution from sourcing training data, design and implementing SOTA machine learning models, testing, benchmarking, and product driven research for model performance improvement, to shipping stable, tested, performant code and services in an agile environment. Engage with a diverse group of research scientists to help solve complex problems in the preclinical domain. Why you? Qualifications & Skills: We are looking for professionals with these required skills to achieve our goals: A degree in a quantitative or engineering discipline (e.g., computer science, computational biology, bioinformatics, engineering, among others); OR equivalent work experience as a professional AI/ML engineer. Experienced in developing deep learning models for solving real world scientific problems. For example, creating a visual transformer to detect anomalous tissue from a tissue sample or creating a semi-supervised model to classify text from physiology references (Note: these are just examples, and not necessarily reflective of specific work you will be doing). An outstanding software engineer and machine learning engineer. Demonstrable expertise and depth in at least one area and breadth across your expertise. Experienced/accomplished in software engineering with advanced skills and expertise in best practices for Pythonic programming, for example refactoring code for efficiency and modularization in PyTorch. Proficiency with standard deep learning algorithms and model architectures, can build new models either using Pytorch functional API or from scratch. Familiarity with current deep learning literature and math of machine learning In-depth knowledge in machine learning best practices, scalable training and deployment, model introspection and evaluation Experience in deep learning for computer vision, including but not limited to image segmentation and object detection Advanced level in PyTorch or Tensorflow. Experience with devop stacks: version control, CI/CD, containerization, etc. A thorough understanding of security and privacy best practices as relates to data and code. Preferred Qualifications & Skills: If you have the following characteristics, it would be a plus: Track record of contributing to open-source projects, or evidence of working collaboratively on codebases Mentality of commit early and often, metrics before models, and shipping high quality production code Experience with video analysis and tracking Experience/familiar with different modules of an ML product interacting with each other asynchronously (say API calls or shared database) Knowledge in disease biology, molecular biology and biochemistry Experience with biological data (e.g., genomics, transcriptomics, epigenomics, proteomics, etc.) Closing Date for Applications: Thursday 10th July 2025 (COB) Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. During the course of your application, you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact . This will help us to understand any modifications we may need to make to support you throughout our selection process. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose to unite science, technology and talent to get ahead of disease together so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or . The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive . Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at

Job description Site Name: London The Stanley Building Posted Date: Jun At GSK we see a world in which advanced applications of Machine Learning and AI will allow us to develop novel therapies to existing diseases and to quickly respond to emerging or changing diseases with personalized drugs, driving better outcomes at reduced cost with fewer side effects. It is an ambitious vision that will require the development of products and solutions at the cutting edge of Machine Learning and AI. If that excites you, we'd love to chat. We're looking for an AI/ML Engineer to help us make this vision a reality. Competitive candidates are outstanding engineers with a track record in developing SOTA deep learning models for solving challenging real world scientific problems and production grade AI-powered software solutions. Our team focuses on the discovery of preclinical digital biomarkers that translate robustly to clinical outcomes. An important outcome of our work is that, while enabling deeper insights into the effects and mechanisms of action of treatments, importantly, it also helps to advance the 3Rs framework, a set of principles that guide the ethical and humane use of animals in scientific research. In this role you will Convert vaguely described biological/drug discovery challenges into well-defined machine learning problems, particularly in the computer vision domain (both images and video). Execute and deliver full AI/ML driven solution from sourcing training data, design and implementing SOTA machine learning models, testing, benchmarking, and product driven research for model performance improvement, to shipping stable, tested, performant code and services in an agile environment. Engage with a diverse group of research scientists to help solve complex problems in the preclinical domain. Why you? Qualifications & Skills: We are looking for professionals with these required skills to achieve our goals: A degree in a quantitative or engineering discipline (e.g., computer science, computational biology, bioinformatics, engineering, among others); OR equivalent work experience as a professional AI/ML engineer. Experienced in developing deep learning models for solving real world scientific problems. For example, creating a visual transformer to detect anomalous tissue from a tissue sample or creating a semi-supervised model to classify text from physiology references (Note: these are just examples, and not necessarily reflective of specific work you will be doing). An outstanding software engineer and machine learning engineer. Demonstrable expertise and depth in at least one area and breadth across your expertise. Experienced/accomplished in software engineering with advanced skills and expertise in best practices for Pythonic programming, for example refactoring code for efficiency and modularization in PyTorch. Proficiency with standard deep learning algorithms and model architectures, can build new models either using Pytorch functional API or from scratch. Familiarity with current deep learning literature and math of machine learning In-depth knowledge in machine learning best practices, scalable training and deployment, model introspection and evaluation Experience in deep learning for computer vision, including but not limited to image segmentation and object detection Advanced level in PyTorch or Tensorflow. Experience with devop stacks: version control, CI/CD, containerization, etc. A thorough understanding of security and privacy best practices as relates to data and code. Preferred Qualifications & Skills: If you have the following characteristics, it would be a plus: Track record of contributing to open-source projects, or evidence of working collaboratively on codebases Mentality of commit early and often, metrics before models, and shipping high quality production code Experience with video analysis and tracking Experience/familiar with different modules of an ML product interacting with each other asynchronously (say API calls or shared database) Knowledge in disease biology, molecular biology and biochemistry Experience with biological data (e.g., genomics, transcriptomics, epigenomics, proteomics, etc.) Closing Date for Applications: Thursday 10th July 2025 (COB) Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. During the course of your application, you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact . This will help us to understand any modifications we may need to make to support you throughout our selection process. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose to unite science, technology and talent to get ahead of disease together so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or . The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive . Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at

Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many global locations across the US, APAC and Europe. Oxford Nanopore employs from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market. Oxford Nanopore's sequencing platform is the only technology that offers real-time analysis, in fully scalable formats from pocket to population scale, that can analyse native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths. Our goal is to enable the analysis of any living thing, by anyone, anywhere! We are looking for a highly motivated individual to join the Research Team as a Protein Analyst with a focus on mass spectrometry to provide high-quality, timely and accurate analyses of protein, peptide and other samples as provided, with a view to advising the direction of research projects and driving them forward. The Details This role will principally be laboratory-based to begin with, and analyses will be split approximately 50:50 between mass spectrometry and other analyses. The role expects significant collaboration with other teams and projects, with the central aim of accelerating research and development of Oxford Nanopore products. The successful candidate will have good laboratory skills, reliability in bench-based practical work, and the ability to carry out sophisticated and routine tasks with equal attention to detail and thoroughness. Applications are encouraged from candidates who can adapt quickly to new challenges and enjoy working with an agile approach to research. The successful candidate will need to work meticulously to a high standard and be able to perform well under pressure to meet deadlines in a demanding and fast-paced environment. What We're Looking For A PhD or equivalent experience in a relevant subject. Experience working with ESI mass spectrometry equipment. Experience with protein sample preparation methods including solid phase extraction, HPLC, buffer exchange methods. The ability to use mass spectrometry software for the analysis of protein digest samples, including proteomics and modification mapping, and to run pre-existing LC-MS methods. Experience preparing mass spectrometry compatible samples. Desirable experience includes: Previous experience with Waters Q-ToF instruments including preventative and reactive maintenance Experience in software requirements for Q-Tof instruments, specifically Waters instruments. Experience with oligonucleotide (DNA and RNA) sample preparation methods. Experience with small molecule mass spectrometry. The ability to develop new LC separation methods over a range of chemistries. The ability to develop new mass spectrometry methods for the analysis of proteins, peptides and small molecules. We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment. If you are looking to utilise your skills to really make a difference to humankind, then consider joining our team and apply today! Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.

CCL 25.05.02 Lead AI Scientist, Small Molecule Discovery, Orion Pharma, Cambridge, UK Conferences upcoming conferences Jobs positions open Consultants COnsulting Companies -Resumes- resumes (positions wanted) From: jobs at ccl.net (do not send your application there ) To: jobs at ccl.net Date: Fri May 2 06:51: Subject: 25.05.02 Lead AI Scientist, Small Molecule Discovery, Orion Pharma, Cambridge, UK Orion is seeking a visionary and technically exceptional Lead AI Scientist- Small Molecule Discovery to join our Molecular Prospecting and Modeling Unit. This newly established role is ideal for a scientist driven to push the boundaries of modern predictive and generative AI methods and redefine how small molecule drug discovery is conducted. If you're passionate about innovating beyond the current state-of-the-art and building transformative solutions that shape the future of drug design, we want to hear from you.We are on a bold digital transformation journey to redefine pharmaceutical R&D through the power of data, machine learning, and AI. As part of this mission, we are building a world-class digital R&D ecosystem that integrates scientific innovation with cutting-edge technology. We are pawing our way to the future by transforming how we discover and design small molecule therapeutics, integrating computational methods with domain expertise in medicinal chemistry, biology, and pharmacology. Join us at the forefront of this transformation and help accelerate the discovery and development of new therapies for patients around the world. About your roleAs Lead AI Scientist, you will act as a thought leader in machine learning and artificial intelligence, spearheading the development of novel methodologies to enable data-driven hit discovery, hit-to-lead progression, and lead optimization. You will work alongside a highly experienced computational team and have a pivotal role in empowering scientists across Orions R&D, including Medicinal Chemistry and DMPK-Tox experts.This role is not project-bound or service-orientedit is about initiating a fundamental evolution in computational drug discovery at Orion. You will have a strong mandate to explore new technologies, implement cutting-edge solutions, and influence the strategic direction of AI-driven design.Your key responsibilities- Developing and validating advanced AI/ML methodologies for molecular generation, prediction, and optimization.- Designing and implementing scalable computational pipelines, models, and tools to be used by the broader modeling and cheminformatics team.- Driving innovation in areas such as foundation models, active learning, and generative chemistry with attention to synthetic feasibility.- Staying at the forefront of scientific and technical advances in AI for drug discovery.- Collaborating with internal computational experts and selected external partners to extend Orions capabilities.- Contributing to scientific publications and participating in the broader scientific community where appropriate.This is a full-time position based in Cambridge, UK. In this position, you will report to the Head of Computational Design based in Espoo, Finland.What we offerAt Orion, your work directly contributes to improving the lives of patients worldwide. We provide:- A forward-looking, collaborative scientific environment with top-tier professionals.- A unique opportunity to drive a technological leap in AI-powered drug discovery.- Access to diverse chemical and biological data and modern compute environments.- Opportunities for scientific publishing and engagement in external collaborations.- Competitive salary, comprehensive health and welfare benefits, and support for international relocation.At Orion, your work creates true impact and well-being for our customers, patients and society at large. Our culture of friendliness, respect, mutual appreciation and diversity creates a safe working environment where you can strive for excellence. We offer a wealth of career paths and development opportunities that support the development of innovative solutions and improving the quality of life.Please visit our website to find further information about our values and Orion as an employer expectationsTo succeed in this role, we expect you to have:- Ph.D. in machine learning, artificial intelligence, computational chemistry, cheminformatics, or a related field.- 5+ years of postdoctoral experience.- Proven track record in developing and applying modern AI/ML methods (e.g., generative models, GNNs, active learning, foundation models)in a scientific context.- Strong coding skills and experience with relevant ML frameworks(e.g., PyTorch, TensorFlow, JAX) and chemistry toolkits (e.g., RDKit).- Deep understanding of molecular representation techniques and their application in modeling.- Experience in designing and implementing robust, scalable AI-driven workflows and tools.- Passion for scientific discovery and the curiosity to explore new frontiers.- Excellent communication and collaboration skills in a multidisciplinary environment.- Fluent written and spoken English.- Experience with organic and medicinal chemistry is highly valued, but deep domain expertise is not required.How to apply and additional informationIf this opportunity excites you, we encourage you to apply! Please submit your cover letter and CV by May 25th, 2025, and let us know what drives your passion for AI in small molecule discovery. You can find the job among our open positions on our website at Unit descriptionOrions pharmaceutical innovations are created within its R&D organization.We employ around 400 top professionals in the field of drug discovery and development. We work globally: in Espoo and Turku in Finland, in Nottingham in England and in New York, NY, USA. Orion R&D and the Innovative Medicines business division are dedicated to making a transformation to become a global player in the pain and oncology therapy areas. Our Medicine Design Department plays a critical role in drug discovery, from target validation to clinical candidate nomination.The Molecular Prospecting and Modeling Unit defines hit-finding strategies for early-stage drug discovery and develops computational methods to support all stages of small molecule discovery. Our unit integrates cheminformatics, AI, molecular modeling, and structural biology to accelerate and guide data-driven drug design.About UsOrion is a globally operating Finnish pharmaceutical company a builder of well-being for over a hundred years.Orion provides meaningful work for more than 3 600 Orionees in Finland and abroad. Orion is known as a responsible and reliable employer where we value each other, strive for the best and build for tomorrow.We develop, manufacture and market human and veterinary pharmaceuticals and active pharmaceutical ingredients. Orion has an extensive portfolio of proprietary and generic medicines and consumer health products. The core therapy areas of our pharmaceutical R&D are oncology and pain. Proprietary products developed by Orion are used to treat cancer, neurological diseases and respiratory diseases, among others.Please submit your cover letter and CV by May 25th, 2025. You can find the job advertisement among our open positions on our website at find the direct link to the job advertisement below, through which you can submit your application and CV.+Kingdom&locationId=&locationLevel=country&mode=locationNOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED were changed to a to fight spam. Before you send e-mail, youneed to change a example: change joe a to Please let your prospective employer know that you learnedabout the job from the Computational Chemistry List Job Listing at .If you are not interested in this particular position yourself, pass it tosomeone who might be some day they may return the favor. Page accessed 96 times since Fri May 2 11:00: GMT

Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many global locations across the US, APAC and Europe. Oxford Nanopore employs from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market. Oxford Nanopore's sequencing platform is the only technology that offers real-time analysis, in fully scalable formats from pocket to population scale, that can analyse native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths. Our goal is to enable the analysis of any living thing, by anyone, anywhere! We are currently seeking a passionate individual to join our Automation Solutions team as an Automation Scientist, who will actively drive the growth of our automation platforms. The Details This exciting and challenging role is responsible for developing and introducing new automated workflows, with a focus on ElysION. This hybrid role, split evenly between lab and desk-based tasks, will involve developing, testing and optimising automated NGS sample preparation protocols, sequencing prepared libraries on our range of sequencing devices and analysing and reporting the results. What We're Looking For In addition to a BSc or equivalent experience in Physics, Chemistry, Biology or other relevant subjects, the applicant will have acquired significant practical laboratory experience. The ideal candidate will be responsible for ensuring the successful delivery of high-impact products, by coordinating with cross-functional teams, managing project timelines, and presenting progress to stakeholders. Required skills, knowledge and competencies: Experience with automation, liquid handling or robotic systems Experience with scripting/programming e.g. Python, Linux, XML etc Experience of basic life science laboratory techniques and equipment e.g. pipetting, normalisation, use of thermocyclers etc Understanding of laboratory best practises Experience in NGS sample preparation DNA extraction methods Attention to detail; ensuring precision and accuracy in experiments, data collection, and analysis Problem solving and critical thinking Analytical skills Collaboration We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment. If you are looking to utilise your skills to really make a difference to humankind, then consider joining our team and apply today! Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job. Oxford Nanopore's goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology enabling the real-time, high-performance, accessible and scalable analysis of DNA and RNA. The technology is used in more than 100 countries to understand the biology of humans and diseases, plants, animals, bacteria, viruses and whole environments. Oxford Nanopore was founded in 2005 as a spin-out from the University of Oxford and now employs over 1000 employees around the world.

Job Description Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many global locations across the US, APAC, and Europe. Oxford Nanopore employs experts from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing, and commercialization. The management team, led by CEO Dr. Gordon Sanghera, has a track record of delivering disruptive technologies to the market. Oxford Nanopore's sequencing platform is unique, offering real-time analysis in fully scalable formats from pocket to population scale, capable of analyzing native DNA or RNA and sequencing any length of fragment to achieve short to ultra-long read lengths. Our goal is to enable the analysis of any living thing, by anyone, anywhere! The Role Our Biologics Development team is responsible for improving the performance of all biological components within our sample preparation kits and flowcells. We are seeking a highly motivated individual with excellent lab skills to join as a Development Scientist. As part of the wider R&D division, we collaborate to deliver new chemistries from conception to customers. This role, based at our Oxford headquarters, will support the development of new nanopore sequencing products, focusing on enhancing fundamental performance metrics to improve outcomes and utility for users of the ONT platform. The successful candidate will be responsible for designing, purifying, and analyzing key protein components that form the backbone of RNA and DNA sequencing chemistries, as well as future nanopore sensing applications. You will interact with various stakeholders across R&D and product divisions in a multidisciplinary environment. What We're Looking For We seek a motivated and detail-oriented candidate with experience in: Biochemical properties of proteins, especially DNA/RNA handling enzymes and membrane proteins. Recombinant protein expression from bacterial systems. Lab-scale purification of proteins using chromatographic methods with AKTA or similar systems. Experimental design and execution focusing on protein function. Targeted chemical modification of proteins. Programming skills in Python, R, or command line for data science. Additional experience in one or more of the following is a plus: Nanopore sensing experiments. Computational tools for protein variant design. Responsibilities Designing and iterating protein variants to improve nanopore sensing performance. Expressing and purifying protein variants at appropriate scales, troubleshooting as needed. Characterizing proteins using biochemical techniques and nanopore-based assays. Analyzing data thoroughly and reporting findings accurately to the team. The ideal candidate will hold a PhD in biochemistry, chemistry, or a related field, or equivalent industrial experience. We value strong attention to detail, organization, and effective communication skills. This role is suited for a dedicated individual eager to learn and grow, with extensive training and mentorship provided. We offer excellent benefits, including a bonus, generous pension contributions, private healthcare, and a competitive salary. Our workspace is in a beautiful environment with landscaped surroundings, water features, and a lake, providing a pleasant working atmosphere. If you want to make a difference through your skills, consider joining our team. Apply today! We are committed to diversity and equal opportunity, assessing all candidates based on merit, qualifications, and ability to perform the job.

CCL 25.05.02 Lead AI Scientist, Small Molecule Discovery, Orion Pharma, Cambridge, UK Conferences upcoming conferences Jobs positions open Consultants COnsulting Companies -Resumes- resumes (positions wanted) From: jobs at ccl.net (do not send your application there ) To: jobs at ccl.net Date: Fri May 2 06:51: Subject: 25.05.02 Lead AI Scientist, Small Molecule Discovery, Orion Pharma, Cambridge, UK Orion is seeking a visionary and technically exceptional Lead AI Scientist- Small Molecule Discovery to join our Molecular Prospecting and Modeling Unit. This newly established role is ideal for a scientist driven to push the boundaries of modern predictive and generative AI methods and redefine how small molecule drug discovery is conducted. If you're passionate about innovating beyond the current state-of-the-art and building transformative solutions that shape the future of drug design, we want to hear from you.We are on a bold digital transformation journey to redefine pharmaceutical R&D through the power of data, machine learning, and AI. As part of this mission, we are building a world-class digital R&D ecosystem that integrates scientific innovation with cutting-edge technology. We are pawing our way to the future by transforming how we discover and design small molecule therapeutics, integrating computational methods with domain expertise in medicinal chemistry, biology, and pharmacology. Join us at the forefront of this transformation and help accelerate the discovery and development of new therapies for patients around the world. About your roleAs Lead AI Scientist, you will act as a thought leader in machine learning and artificial intelligence, spearheading the development of novel methodologies to enable data-driven hit discovery, hit-to-lead progression, and lead optimization. You will work alongside a highly experienced computational team and have a pivotal role in empowering scientists across Orions R&D, including Medicinal Chemistry and DMPK-Tox experts.This role is not project-bound or service-orientedit is about initiating a fundamental evolution in computational drug discovery at Orion. You will have a strong mandate to explore new technologies, implement cutting-edge solutions, and influence the strategic direction of AI-driven design.Your key responsibilities- Developing and validating advanced AI/ML methodologies for molecular generation, prediction, and optimization.- Designing and implementing scalable computational pipelines, models, and tools to be used by the broader modeling and cheminformatics team.- Driving innovation in areas such as foundation models, active learning, and generative chemistry with attention to synthetic feasibility.- Staying at the forefront of scientific and technical advances in AI for drug discovery.- Collaborating with internal computational experts and selected external partners to extend Orions capabilities.- Contributing to scientific publications and participating in the broader scientific community where appropriate.This is a full-time position based in Cambridge, UK. In this position, you will report to the Head of Computational Design based in Espoo, Finland.What we offerAt Orion, your work directly contributes to improving the lives of patients worldwide. We provide:- A forward-looking, collaborative scientific environment with top-tier professionals.- A unique opportunity to drive a technological leap in AI-powered drug discovery.- Access to diverse chemical and biological data and modern compute environments.- Opportunities for scientific publishing and engagement in external collaborations.- Competitive salary, comprehensive health and welfare benefits, and support for international relocation.At Orion, your work creates true impact and well-being for our customers, patients and society at large. Our culture of friendliness, respect, mutual appreciation and diversity creates a safe working environment where you can strive for excellence. We offer a wealth of career paths and development opportunities that support the development of innovative solutions and improving the quality of life.Please visit our website to find further information about our values and Orion as an employer expectationsTo succeed in this role, we expect you to have:- Ph.D. in machine learning, artificial intelligence, computational chemistry, cheminformatics, or a related field.- 5+ years of postdoctoral experience.- Proven track record in developing and applying modern AI/ML methods (e.g., generative models, GNNs, active learning, foundation models)in a scientific context.- Strong coding skills and experience with relevant ML frameworks(e.g., PyTorch, TensorFlow, JAX) and chemistry toolkits (e.g., RDKit).- Deep understanding of molecular representation techniques and their application in modeling.- Experience in designing and implementing robust, scalable AI-driven workflows and tools.- Passion for scientific discovery and the curiosity to explore new frontiers.- Excellent communication and collaboration skills in a multidisciplinary environment.- Fluent written and spoken English.- Experience with organic and medicinal chemistry is highly valued, but deep domain expertise is not required.How to apply and additional informationIf this opportunity excites you, we encourage you to apply! Please submit your cover letter and CV by May 25th, 2025, and let us know what drives your passion for AI in small molecule discovery. You can find the job among our open positions on our website at Unit descriptionOrions pharmaceutical innovations are created within its R&D organization.We employ around 400 top professionals in the field of drug discovery and development. We work globally: in Espoo and Turku in Finland, in Nottingham in England and in New York, NY, USA. Orion R&D and the Innovative Medicines business division are dedicated to making a transformation to become a global player in the pain and oncology therapy areas. Our Medicine Design Department plays a critical role in drug discovery, from target validation to clinical candidate nomination.The Molecular Prospecting and Modeling Unit defines hit-finding strategies for early-stage drug discovery and develops computational methods to support all stages of small molecule discovery. Our unit integrates cheminformatics, AI, molecular modeling, and structural biology to accelerate and guide data-driven drug design.About UsOrion is a globally operating Finnish pharmaceutical company a builder of well-being for over a hundred years.Orion provides meaningful work for more than 3 600 Orionees in Finland and abroad. Orion is known as a responsible and reliable employer where we value each other, strive for the best and build for tomorrow.We develop, manufacture and market human and veterinary pharmaceuticals and active pharmaceutical ingredients. Orion has an extensive portfolio of proprietary and generic medicines and consumer health products. The core therapy areas of our pharmaceutical R&D are oncology and pain. Proprietary products developed by Orion are used to treat cancer, neurological diseases and respiratory diseases, among others.Please submit your cover letter and CV by May 25th, 2025. You can find the job advertisement among our open positions on our website at find the direct link to the job advertisement below, through which you can submit your application and CV.+Kingdom&locationId=&locationLevel=country&mode=locationNOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED were changed to a to fight spam. Before you send e-mail, youneed to change a example: change joe a to Please let your prospective employer know that you learnedabout the job from the Computational Chemistry List Job Listing at .If you are not interested in this particular position yourself, pass it tosomeone who might be some day they may return the favor. Page accessed 70 times since Fri May 2 11:00: GMT

Background Sygnature Discovery is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional facilities in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City. Its staff of over 1,000, which includes 900 scientists, partners with global pharma , biotech and NFP organisations. Since 2004, Sygnature Discovery has delivered over 40 novel pre-clinical and 22 clinical compounds, with its scientists named on over 170 patents. Therapeutic areas of expertise include oncology, inflammation and immunology, neuroscience, metabolic diseases, infectious diseases, fibrotic diseases and more.To find out more, please visit . About the role Biophysicists at Sygnature Discovery play essential roles in supporting and leading integrated client projects as well as developing and delivering customised biophysical assays to support and drive preclinical drug discovery campaigns. Through the generation of high-quality data, such as affinity and kinetic data to inform structure-activity relationships (SAR) and mechanism of action (MoA) investigations for complex systems, biophysics forms a key component of many single- and multi-discipline projects. Due to continued growth, we are expanding our talented Biophysics team at our Nottingham site. This is a full-time, onsite position. Role Responsibilities: Utilise knowledge and experience of biophysical technologies on active drug discovery projects. Develop a detailed understanding of biophysical approaches and share knowledge of multiple techniques with the wider biophysics team. Present and share data and expertise to our global, multi-disciplinary biophysics and protein science groups. Be responsible for the maintenance of biophysical instrumentation. Provide support for other members of the team, such as junior team members or new instrument users, including instrument specific training where required. Candidate Requirements: PhD or relevant experience in Pharmacology, Biochemistry or a related Biology-specific discipline. Hands-on expertise with SPR, MST, and DSF/FTSA is ideal. Experience with BLI, ITC, and NMR is desirable. A strong scientific track record with experience built within a drug discovery environment is highly desirable. A working knowledge of current trends in drug discovery. Ability to develop novel assays from first principles and interpret complex biological datasets. Aptitude for proactive troubleshooting and adoption of industry-leading practices for generation and analysis of robust scientific data Ability to work independently and collaboratively within a fast-paced environment. Experience in project leadership or line management is desirable but not essential. Excellent written and verbal communication skills and an ability to present complex scientific ideas and datasets to key stakeholders. Benefits Here at Sygnature Discovery, we take pride in offering an excellent training and benefits package. As a valued employee, you will be entitled to: - 25 days annual leave (rising with service) plus bank holidays, and buy/sell scheme - Private Medical Insurance - Life Insurance - Employee Assistance Programme and mental health first aiders - Enhanced Family Friendly Policies - Sygnature Group Pension Scheme - 1 paid volunteer day per year - A host of flexible benefits to support your wellbeing and lifestyle Why Sygnature Discovery At Sygnature Discovery, we embody excellence in everything we do. From pioneering research to ground-breaking discoveries, we set the standard for scientific innovation. But it's collaboration that truly defines us. Across continents and disciplines, we unite to solve complex challenges, driven by a shared passion for improving lives worldwide. We understand the importance of creating a work environment that empowers you to thrive. That's why we have fostered a culture of collaboration and support, providing pathways for both professional and personal development. This includes a diverse range of bespoke training and development designed to accelerate both your personal and career growth. We are committed to fostering diversity and inclusion throughout our organisation. We encourage applications from individuals of all backgrounds, ethnicity, gender identity, sexual orientation, disability, neurodiversity, age, family or parental status, beliefs, nationalities and religions. We strive to cultivate an inclusive environment where all our colleagues feel empowered to bring their true selves to work. If you're interested in joining a company that places people at the heart of its business, please submit your application as soon as possible as we will be interviewing on an ongoing basis. If you have any questions or need further information, please contact the Talent Acquisition team at .Please do not submit your application to this email address. For more information on life at Sygnature Discovery, visit

Company Summary: Quotient Therapeutics Ltd is a privately held, early-stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need. The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS). We are an equal opportunity employer. Position Summary: We are seeking a Head of High-Throughput Lab that reports to senior leadership and leads a team of bench scientists that produce high-quality, multi-omic data at scale. Specifically this team is responsible for the end-to-end processing of samples, including histology, cell sorting, extraction of genetic material and preparation for downstream omics analysis. The role includes oversight of lab operations, defining processes that enable consistent quality, instilling a collaborative, excellence-focused culture where the status quo is constantly pressure tested. We are looking for someone who can motivate teams to rally behind a shared mission and brings prior experience scaling and running high-throughput operations. The ideal candidate operates with a growth mindset, pays attention to detail, and has a deep-rooted desire to achieve excellence. Being collaborative is key - in this function, there will be many interactions with other leaders at Quotient, such as in data science, assay development, and target biology. This role is based in the vicinity of Cambridge, UK and will be primarily based on site. All applicants will require permission to work in the UK. Key Responsibilities: Lead and develop team of scientists in the high throughput lab, including process definitions, task prioritization and scheduling, health and safety and continuous improvement Work directly with senior leadership to drive towards major corporate goals and own strategic initiatives, such as optimizing operational efficiency Take a leading role in defining best practices and setting team culture, working towards shared KPIs, executing against ambitious timelines in alignment with business needs Set a high bar for excellence, quality and safety, continuously investing into improved ways-of-working, acting with an innovation mindset Collaborate with other leaders at Quotient, constantly seeking ways to improve how we operate Interact with key suppliers and advisors, minimizing bottlenecks and enabling high-quality relationships Requirements: MS or Ph.D. in biology or related discipline with 10+ years of relevant post-academic experience with an excellent track record of operating and scaling high-throughput labs 3+ years of experience hiring, leading and developing teams of 10+ scientists Expertise in performing genomics and other omics experiments at scale, using automation equipment Experience defining weekly schedules for complex, multi-project and multi-person lab operations Knowledge of health & safety best practices, enabling a safe working environment Proven track record of defining processes and putting in place continuous improvement methods, enabling data generation to routinely deliver against ambitious timelines About Flagship Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at . Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. Apply for this job indicates a required field First Name Last Name Email Phone Resume/CV Enter manually Accepted file types: pdf, doc, docx, txt, rtf Enter manually Accepted file types: pdf, doc, docx, txt, rtf Employment Title Select Start date year End date month Select End date year Current role Will you now or in the future require sponsorship for employment visa status in the United Kingdom? Select If you'll require the company to commence ("sponsor") an immigration or work permit case in order to employ you, either now or at some point in the future, then you should select Yes. 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What do you want to search? Keyword Apprenticeship Type Location Divisional Administration Assistant Apprentice , Apply From: 28/04/2025 Learning Provider Delivered by EALING, HAMMERSMITH & WEST LONDON COLLEGE Employer UNIVERSITY COLLEGE LONDON Vacancy Description Act as a first point of contact for enquiries to the Associate Directors, co-ordinating meeting requests and handling; email, telephone, and in-person enquiries Process room bookings for Divisional committees, meetings and events Arrange hospitality for meetings, events and interviews and support these events in-person Provide administrative support, organise seminars, book venues, meetings suport and other administrative duties to the Associate Director (Education), and other Associate Directors for Divisional initiatives Support the maintenance of the Division's intranet including SharePoint pages Produce a weekly digital Divisional newsletter Assist with minute taking in Divisional meetings Provide administrative support for Division-wide data collection exercises Assist with the organisation and publicity of Divisional events including, conferences, seminars and workshops Attend and contribute to regular Divisional Professional Service team meetings Actively follow and promote UCL's policies, including its Equal Opportunities Policy Maintain an awareness and observation of Fire and Health & Safety Regulations Any other relevant duties as required by the Department manager and Head of Department Key Details Vacancy Title Divisional Administration Assistant Apprentice Employer Description UCL is one of the world's top universities. At its establishment in 1826, UCL was radical and responsive to the needs of society, and this ethos - that excellence should go hand-in-hand with enriching society - continues today. UCL is a multi-faculty college of the University of London with a population of over 17,000 students, from more than 130 different countries. With an annual turnover exceeding £1 billion, it is a major research and education hub in London and globally.The Division of Biosciences is one of the world's foremost centres for research and teaching in biological sciences and one of the largest Divisions within UCL. The Division has four Research Departments:- Cell and Developmental Biology (CDB)- Genetics, Evolution and Environment (GEE),- Neuroscience, Physiology and Pharmacology (NPP)- Structural and Molecular Biology (SMB)Each department undertakes a significant amount of research and teaching, and has a diverse portfolio addressing all areas of biology from protein interactions to cell function, organism development, genetics, population studies and the environment. Vacancy Location Gower Street London WC1E 6BT Wage Frequency Custom Number of Vacancies 1 Vacancy Reference Number Key Dates Apply From 28/04/2025 Closing Date For Applications 2025-05-:59:59 Interview Begin From Possible Start Date 2025-07-:00:00 Training Training to be Provided Business Administrator Level 3 Apprenticeship Standard: You will be expected to attend college at Hammersmith Campus of West London College for one day per week during term time to complete the required classroom-based training Learning Provider EALING, HAMMERSMITH & WEST LONDON COLLEGE Skills Required Communication skillsIT skillsAttention to detailOrganisation skillsCustomer care skillsProblem solving skillsAdministrative skillsLogicalTeam workingInitiativePatienceIndependentWillingness to learn Apply Now

We are seeking a highly skilled and independent proteomics expert to join our Bioscience Crop Protection R&D function at Syngenta. This critical role is required to deliver multidisciplinary collaborative work programmes linked to lead discovery and safer-by-design initiatives within our Target Identification group. The successful candidate will leverage advanced proteomic techniques (including activity-based protein profiling, affinity-based methods, stability-based proteome profiling) to drive target identification and characterisation, which are essential for the development of innovative pest control solutions and enhance our understanding of molecular toxicological mechanisms to improve assessments of human safety. Responsibilities will include the implementation and optimisation of these techniques, managing complex proteomic data analysis and fostering strong collaboration across multi-disciplinary teams. Company Description Syngenta is a leading science based ag-tech company helping to improve global food security by enabling millions of farmers to make better use of available resources. Through world class science and innovative crop solutions, our 30,000 people in over 100 countries are working to transform how crops are grown.We are committed to rescuing land from degradation, enhancing biodiversity and revitalizing rural communities. Syngenta Crop Protection is a leader in agricultural innovation, bringing breakthrough technologies and solutions that enable farmers to grow healthy and nutritious food while taking care of the planet. We offer a leading portfolio of crop protection solutions for plant and soil health, as well as digital solutions that transform the decision-making capabilities of farmers. Our 17,900 employees serve to advance agriculture in more than 90 countries around the world. Syngenta Crop Protection is headquartered in Basel, Switzerland, and is part of the Syngenta Group. Our employees reflect the diversity of our customers, the markets where we operate and the communities which we serve. Regardless of your position, you will have a vital role in safely feeding an ever-increasing population while taking care of our planet. Join us and help shape the future of agriculture. Qualifications What are we looking for? Ph.D. in Proteomics, Biochemistry, Molecular biology, or a related field. Extensive experience with quantitative mass spectrometry-based proteomic workflows and technologies to understand complex biological questions in the domains of target identification and toxicology. Proficiency in bioinformatics and statistical tools to process and interpret quantitative proteomic data, identifying trends, patterns, and meaningful biological insights. Hands on experience of instrument set-up and data-acquisition. Ability and desire to work as part of a team and to work without technical supervision. Experience mentoring and training scientific colleagues in proteomic methodologies and data analysis Strong critical thinking and communication skills for collaboration and reporting. Additional Information Our site Jealott's Hill International Research Centre UK is situated in pleasant semi-rural surroundings between Bracknell and Maidenhead and is the place of work for approximately 800 Syngenta scientists and support staff. Jealott's Hill is one of the main global research and development sites and key activities include research into discovery of new active ingredients, new formulation technologies, product safety and technical support of our product range. What we offer Extensive benefits package including a generous pension scheme, bonus scheme, private medical & life insurance. Up to 31.5 days annual holiday. The chance to work as part of a team to address the current and future needs of the agricultural sector and help feed an ever-increasing population. A vibrant growth and learning culture and wide range of training options. We offer a position which contributes to valuable and impactful work in a stimulating and international environment. An open, supportive, and collaborative working culture. Syngenta has been ranked as a top 5 employer and number 1 in agriculture by Science Journal. Syngenta is an Equal Opportunity Employer and does not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Learn more about our D&I initiatives here: Jealott's Hill has Disability Confident certification. We are committed to making all stages of our recruitment process accessible to all candidates and our Jealott's Hill site are a Disability Confident Level 2 Employer. Please let us know if you need any assistance or reasonable adjustments throughout your application and we will do everything we can to support you.

About the role We have an exciting opportunity for a a talented and versatile Principal Scientist to join our Bioperformance group opportunity to grow and lead in a dynamic, matrix organization focused on developing innovative insecticides. You will not only contribute your scientific expertise but also play a crucial leadership role, while being responsible for managing and developing team members, setting priorities, providing feedback, and offering development coaching. Key responsibilities will include: Leading and contributing to various stages of the insecticide discovery pipeline, with a focus on enhancing the Bioperformance profile of insect control products. Fostering a positive team culture that prioritizes HSE, effective data management, and innovative thinking in insect control research. Applying entomological knowledge to develop and optimize novel insecticides, considering insect biology, behaviour, and resistance mechanisms. Develop expertise in ADME (Absorption, Distribution, Metabolism, and Excretion) and metabolism studies, focusing on understanding the pharmacokinetics and metabolism of novel insecticides in target insects, beneficial insects, plants, and other relevant matrices to improve biological performance. Design and conduct bioassays to evaluate the efficacy of potential insecticides against various insect pests, including resistant populations. Collaborating with analytical teams on method development for insecticide detection and quantification in various samples, and interpret complex data to optimize insecticide candidates for enhanced Bioperformance. Working within a matrix structure, managing multiple projects and reporting lines, while fostering collaboration with cross-functional teams to achieve insect control research goals. Company Description Syngenta Crop Protection is a leader in agricultural innovation, bringing breakthrough technologies and solutions that enable farmers to grow healthy and nutritious food while taking care of the planet. We offer a leading portfolio of crop protection solutions for plant and soil health, as well as digital solutions that transform the decision-making capabilities of farmers. Our 17,900 employees serve to advance agriculture in more than 90 countries around the world. Syngenta Crop Protection is headquartered in Basel, Switzerland, and is part of the Syngenta Group. Our employees reflect the diversity of our customers, the markets where we operate and the communities which we serve. Regardless of your position, you will have a vital role in safely feeding an ever-increasing population while taking care of our planet. Join us and help shape the future of agriculture. Qualifications What we are looking for? Ph.D. in Entomology, Agricultural Sciences, Biology, Biochemistry, Chemistry, or a related field relevant to insect control research and Bioperformance. Extensive experience in insecticide research or a related field, with the ability to manage and develop team members, while fostering a positive team culture. Strong understanding of insect biology, physiology, and behaviour, as well as crop protection discovery pipelines and factors influencing insecticide bioperformance. Experience in designing and conducting insect bioassays and interpreting results. Proven track record of scientific publications and presentations in fields related to entomology, insect control, and bioperformance. Proficiency in data analysis and interpretation, with experience in using relevant software tools. Proven ability to thrive in a matrix organization, managing multiple insecticide discovery projects, with the ability to influence across diverse functional areas. Desired skills Experience with analytical techniques such as LC-MS/MS or HPLC. Familiarity with ADME concepts and their application in insecticide research and Bioperformance optimization. Experience in studies involving multiple biological matrices (e.g., insects, plants, soil, mammals) relevant to insecticide development. Knowledge of insecticide modes of action, resistance mechanisms, environmental fate, and factors affecting Bioperformance. Familiarity with computational tools, modelling techniques and the mindset to enable them. Strong project management skills and ability to navigate complex organizational structures in the context of insecticide development programs. Additional Information Our site Jealott's Hill International Research Centre UK is situated in pleasant semi-rural surroundings between Bracknell and Maidenhead and is the place of work for approximately 800 Syngenta scientists and support staff. Jealott's Hill is one of the main global research and development sites and key activities include research into discovery of new active ingredients, new formulation technologies, product safety and technical support of our product range. What we offer Extensive benefits package including a generous pension scheme, bonus scheme, private medical & life insurance. Up to 31.5 days annual holiday. We offer a position which contributes to valuable and impactful work in a stimulating and international environment. The chance to work as part of a global team to address the current and future needs of the agricultural sector and help feed an ever-increasing population. A vibrant growth and learning culture and wide range of training options. Syngenta has been ranked as a top 5 employer and number 1 in agriculture by Science Journal. Syngenta is an Equal Opportunity Employer and does not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Learn more about our D&I initiatives here: Jealott's Hill has Disability Confident certification. We are committed to making all stages of our recruitment process accessible to all candidates and our Jealott's Hill site are a Disability Confident Level 2 Employer. Please let us know if you need any assistance or reasonable adjustments throughout your application and we will do everything we can to support you.

At LabGenius, our mission is to accelerate the discovery of next-generation therapeutic antibodies. To do this, we've pioneered the development of EVA - a smart robotic platform that's capable of designing, conducting and, critically, learning from its own experiments. For our wholly-owned pipeline, we're using our closed-loop discovery engine to establish a pipeline of highly selective T-cell engagers and ADCs for the treatment of solid tumours. LabGenius has raised >£58M and is backed by top-tier investors, including M Ventures, Octopus Ventures, LG Corp, Atomico, Kindred Capital, Lux Capital and Obvious Ventures amongst others. The company is headquartered in London (UK) where we've established a state-of-the-art antibody engineering facility. The company is staffed by a multidisciplinary team of more than 50 scientists and engineers. As a Senior Software Engineer at LabGenius, you will collaborate with our talented team of scientists, data scientists and software engineers to deliver our ambitious internal and partnered drug discovery programmes, helping us build a future where AI rapidly engineers novel, life-enhancing biotherapeutics. You will do this by building tools and services which automate experiments and process scientific data at scale. What you'll do in this role Work with our Data Scientists to productionise our machine learning drug discovery platform Lead the design and build of software solutions to help our wet lab scientists generate high quality results Configure, maintain and build integrations for our lab information management system (Benchling) Work closely with lab and data scientists to understand their problems and offer solutions Use Google Cloud Platform to deploy, manage and secure applications and data. Work to maintain and improve the quality of our software, exemplifying best practices for testing, code review, security, documentation, and architecture. What we're looking for Background in a scientific field (via education or experience) CI/CD pipeline familiarity UI development using React and TypeScript/JavaScript (preferred) Exposure to LIMS/ELN systems such as Benchling (preferred) Strong data handling and analytical capabilities Ability to work independently and collaborate effectively Interest in molecular biology, protein engineering, and lab automation What you'll receive from us Aside from being part of our brilliant, purpose-driven team, you'll also enjoy: Financial Discretionary performance-linked annual bonus A generous stock option plan 3x Salary Life Insurance with YuLife Health Shield Cash Back Plan on day-to-day health expenses 5% pension, with an additional top up on tax savings from us Free Will-writing Service Health Private Medical Insurance, including dental and optical (currently with AXA) Discounted gym membership through either AXA or HealthShield 24/7 access to GP Services Access to the Cycle to Work scheme: to make your commute cheaper, healthier and a whole lot greener Easy access to the on-site gym and climbing wall to break a sweat or indulge your inner monkey available at competitive rates Time-Off 25 days annual leave (plus the bank holidays) Up to 20 days paid sick leave (including mental health days - no questions asked) 3 days paid emergency leave so it doesn't eat into your relaxation time 1 week paid bereavement leave plus 1 day to attend a funeral 1 day paid for moving home Wellbeing Employee Assistance Programme including access to coaching and CBT sessions Team-building Weekly team lunches through Feedr. A programme of social events both company-wide and within your own teams Diversity & Inclusion We believe that diversity makes for innovative, exceptional teams. We are an equal opportunity employer and do not discriminate based on gender, race, colour, religion or belief, national origin, age, sexual orientation, marital status, disability, or any other protected class. If you don't feel like you meet every single requirement of this role, we still want to hear from you! We encourage you to apply, have a discussion with us about the role or others that we may have at LabGenius either now or in the future, together we can build more inclusive workplaces.

Background Sygnature Discovery is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional facilities in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City. Its staff of over 1,000, which includes 900 scientists, partners with global pharma , biotech and NFP organisations. Since 2004, Sygnature Discovery has delivered over 40 novel pre-clinical and 22 clinical compounds, with its scientists named on over 170 patents. Therapeutic areas of expertise include oncology, inflammation and immunology, neuroscience, metabolic diseases, infectious diseases, fibrotic diseases and more.To find out more, please visit . About the role A fantastic opportunity has arisen to join our Cellular Pharmacology department as a Senior Principal Scientist/Principal Scientist (subject to experience) at our Glasgow office. This is a full-time, on-site position. The primary responsibility will be to lead and support the cell biology team. Reporting to the Director of Cellular Pharmacology, they will support driving scientific excellence within the cell biology team and working with other principal scientists to support operations across the department. Expert knowledge of cellular pharmacology and its role in integrated drug discovery is essential, as this role will provide technical oversight across the cell biology team and give scientific guidance and mentorship to project teams. Experience in directing cell-based assays, cell line generation, and receptor biology is a must, along with expertise in a range of technical and functional/therapeutic areas. Experiencein GPCR research would be highly desirable. This is a great opportunity for a senior scientist with significant relevant scientific experience looking to develop further leadership skills, or for an existing Principal scientist seeking to join a global CRO, working on exciting, high-impact projects. We're looking for someone with a creative, forward-thinking mindset, capable of driving innovative solutions and strategies. A strong team player, they will value and foster collaboration and have a track record of getting the best out of their team - driving exceptional results while demonstrating a commitment to continuous improvement. Main Duties and Responsibilities: Providing strong technical oversight across all work carried out within the cell biology team - may have some lab presence but will also have other significant non-lab-based roles and responsibilities. Support growth and development of the cell biology team - including capability build strategy. Involved in client project initiation and retention and/or pitching for new business. Scheduling of long-term work-plans over agreed timelines to ensure the objectives of the team(s) are met. Responsible for co-ordinating delivery of high-quality scientific data, interpretation and provides project direction to project teams together with the alignment of extended scientific disciplines within setting. Identifying areas for operational and process improvement/ efficiencies/ expansion to provide a scalable structure for future Cell biology team and Departmental growth. Line management duties (multiple direct reports, APS level and below) - takes a leading role in resource management, recruitment, and the development of scientists within the team. Candidate Requirements: PhD in relevant discipline (Cell Line Biology) or equivalent, with Drug Discovery experience in industry and/or relevant Postdoc. Strong technical insights and troubleshooting in cell-based assays, cell line generation, and receptor biology work. Experience of senior level interaction with key stakeholders, including report writing and presentation of findings to both scientific and non-scientific audiences. Significant experience of multi-stream allocation of work to others and project leadership. Project-wide assessment of resources, timescales, and progress, including finalisation of quotes. Significant experience of performance management, appraisal, and identification of others operational training and development needs, including mentoring, training others, and transferring knowledge (written and verbal). Considerable experience of providing strategic input into team operational activities, improving processes/efficiencies, and supporting growth. Demonstrable exceptional scientific expertise. A proven track record in positive support, engagement and influencing skills at senior management level. Benefits Here at Sygnature Discovery, we take pride in offering an excellent training and benefits package. As a valued employee, you will be entitled to: - 25 days annual leave (rising with service) plus bank holidays, and buy/sell scheme - Private Medical Insurance - Life Insurance - Employee Assistance Programme and mental health first aiders - Enhanced Family Friendly Policies - Sygnature Group Pension Scheme - 1 paid volunteer day per year - A host of flexible benefits to support your wellbeing and lifestyle Why Sygnature Discovery At Sygnature Discovery, we embody excellence in everything we do. From pioneering research to ground-breaking discoveries, we set the standard for scientific innovation. But it's collaboration that truly defines us. Across continents and disciplines, we unite to solve complex challenges, driven by a shared passion for improving lives worldwide. We understand the importance of creating a work environment that empowers you to thrive. That's why we have fostered a culture of collaboration and support, providing pathways for both professional and personal development. This includes a diverse range of bespoke training and development designed to accelerate both your personal and career growth. We are committed to fostering diversity and inclusion throughout our organisation. We encourage applications from individuals of all backgrounds, ethnicity, gender identity, sexual orientation, disability, neurodiversity, age, family or parental status, beliefs, nationalities and religions. We strive to cultivate an inclusive environment where all our colleagues feel empowered to bring their true selves to work. If you're interested in joining a company that places people at the heart of its business, please submit your application as soon as possible as we will be interviewing on an ongoing basis. If you have any questions or need further information, please contact the Talent Acquisition team at .Please do not submit your application to this email address. For more information on life at Sygnature Discovery, visit

ABOUT THE ROLE At DSV we're looking for future Founders, entrepreneurially minded individuals with industry-specific technical and commercial domain expertise eager to solve urgent unmet challenges through venture building. You will join DSV's venture creation programme as a Founder in Residence and work closely with the DSV team, using our methodology , to spin-out a new company. During the programme, you'll work on all aspects related to venture creation in this opportunity area, including working out the optimal approach to solve for the desired outcome, building a team and building a viable business case. Once the new venture is incorporated with pre-seed investment from DSV, you and your co-founders will own the majority stake in the business and continue receiving support from the DSV team post-spinout. The role is full-time, fully remote until venture incorporation and spin-out, after - TBD. THE OPPORTUNITY AREA Over 6 million individuals live with Parkinson's disease (PD) today, and this number is projected to reach 12 million globally by 2040 as populations age. Whilst current therapies do offer symptomatic relief from debilitating motor symptoms, no clinically approved drug intervenes at root cause, meaning disease progression cannot be prevented. In addition, emerging therapeutics which show great promise in animal models of PD often fail to translate in the clinical setting, with even the most successful clinical trials reporting incremental benefit, often capped by dose limiting toxicity. To address this, we are partnering with Parkinson's UK to develop precise, next generation therapies which target true disease modifying nodes in previously unimagined ways. As PD is a multi-pathway pathology, spanning oxidative stress, impaired autophagy, mitochondrial dysfunction and neuroinflammation, the efficacy of single pathway approaches is constrained. OUR APPROACH We are designing a therapeutic approach that will target master homeostatic regulators which can simultaneously correct numerous PD pathways, changing the course of disease. We believe this has the potential to transform patient lives by slowing, halting or even reversing disease progression. This pathway has been the focus of drug development in the past but not been drugged successfully through classic approaches. We are looking to unlock this through the use of novel modalities and a clever target selection and targeting strategy that has the potential to overcome the many feedback looks regulating this pathway. WHO SHOULD APPLY Essential (must-have): PhD in neuroscience or other field relevant to the project; Extensive, systems-level knowledge of Parkinson's disease, including at the cellular and molecular level; Expertise in oxidative stress and/or neuroprotective pathways; Experience in cellular, molecular and/or biochemical approaches to drug discovery for CNS disorders; Experience working in biotech/pharma or an alternative setting which requires strong commercial awareness and understanding of the drug development process; Entrepreneurial spirit, likely demonstrated through impactful innovation; You are innovative, creative, and guided by first-principles thinking; You are highly motivated to create curative solutions for PD patients. Preferred (nice-to-have): Broad knowledge of brain-specific drug delivery techniques; Experience in nucleic acid based payloads (ASO/siRNA/DNA) and delivery techniques; Track record of high quality publications in the field, or thought leadership in the field; High level industry experience in either pharma, biotech, scientific start-ups, life sciences consulting, life sciences VC, or have previously been an inventor/contributor on patents, etc.; Fundraising experience at seed and Series A stages, with established investor contacts. OUR OFFER By joining DSV, you'll be joining a team of operators who have founded companies and led translation of science at some of the most respected universities, charities, funds and government agencies. 2/3 of the team have founded or led a company at C-suite and 65% have a PhD. Our team dedicate several hours every week to each Founder/founding team to provide tailored guidance, resources and feedback covering every aspect of what it takes to successfully launch a new venture from both the tech and commercial perspectives: We provide optimised, purpose-built, proprietary tools, resources and processes to help create high-impact ventures from scratch, using our venture creation methodology; We draw on opportunity area specific know-how provided by our Partner organisation - Parkinson's UK - working collaboratively with their team of experts and Advisors; We provide £250k launch investment (subject to Investment Committee approval) to incorporate the new venture and develop early proof-of-concept data that's needed to attract high profile VCs as well as non-dilutive grant funding; We provide guaranteed income of £4,166 per month paid to each Founder-in-Residence as a fixed consultancy fee until the company is launched and the pre-seed investment is secured; You and the current Founder-in-Residence, together with any additional co-founders, will collectively own a majority equity stake in the company; We provide continuous support after post spin-out, including fundraising, commercial partnerships, recruitment and team-building (amongst other things); plus There are dozens of Founders currently at DSV across sectors working collaboratively and supporting one another - a unique resource to draw on. WHO YOU'LL BE JOINING You will be joining Dr. Kiren Baines-Mortimore, an accomplished scientific leader with many years of experience across drug discovery and development. Kiren, is the former co-founder and CSO at Extracellular, a cultivated meat CDMO. Prior to founding Extracellular, Kiren was the Analytical Development and Quality Control Lead at eXmoor Pharma,where she supported clients in the cell and gene therapy sector with process and analytical development, manufacturing, and commercialization. Earlier in her career, Kiren contributed to drug discovery initiatives at Charles River Laboratories. Kiren earned her PhD in Cell Biology from the University of Bristol. Kiren's background in Parkinson's combined with her expertise in drug development, along with her outstanding professionalism and ambition, makes her a top talent to work with. ABOUT DSV Deep Science Ventures is creating a future in which both humans and the planet can thrive. We use our unique venture creation process to create, spin-out and invest into science companies, combining available scientific knowledge and founder-type scientists into high-impact ventures. We operate in 4 sectors: Pharmaceuticals, Climate, Agriculture and Computation, tackling the challenges defining those areas by taking a first principles approach and partnering with leading institutions. ABOUT OUR PARTNERSHIP WITH PARKINSON'S UK In a landmark collaboration that marries scientific prowess with an unwavering dedication to improving patient lives, Deep Science Ventures, an avant-garde venture creator headquartered in London, has announced a pioneering partnership with Parkinson's UK , the leading charity driving better care, treatments, and quality of life for those affected by Parkinson's. This strategic alliance is set to merge DSV's unique invention method with Parkinson's UK's rich insights into patient care, igniting the creation of a new, dedicated company. The aim is to propel the most innovative and efficient therapeutic approach into real-world application, funded by the transformative Parkinson's Virtual Biotech initiative - Parkinson's UK investment arm.