Novartis Farmacéutica

Director: AI Systems Reliability, Testing & Performance Location: London Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you. The Director, AI Systems Reliability, Testing & Performance is a senior technical AI leadership role within Data Science & AI, responsible for defining how AI systems across Novartis Development are evaluated, tested, validated, benchmarked, monitored, and continuously improved throughout their lifecycle. This role owns the technical evidence required to determine whether AI systems are reliable, robust, secure, and fit-for-use across Novartis Development. The role defines common approaches for AI evaluation, benchmarking, testing, validation, monitoring, and production-readiness across agentic AI systems, predictive models, retrieval systems, digital twins, and other AI capabilities. The Director provides technical leadership in AI evaluation science, reliability engineering, validation, adversarial testing, and performance assessment. Key areas of focus include model and agent evaluation, benchmarking, failure-mode analysis, drift detection, digital twin validation, AI red teaming, observability, traceability, and technical evidence generation supporting regulated and business-critical AI systems. This is not a Governance, Product Management, PMO, or infrastructure operations role. Governance owns policies, risk frameworks, and approval processes. Product teams own roadmaps, adoption, and value realization. DDIT and engineering teams own platforms, infrastructure, and operational services. Success means Development AI systems are supported by objective evidence demonstrating how they perform, where they fail, and whether they remain fit-for-use over time.

Novartis in London seeks a Director of AI Systems Reliability, Testing & Performance to define how AI systems across the Development portfolio are evaluated, tested, validated, and monitored for production-readiness. You will lead reliability engineering, adversarial testing, drift detection, and observability, providing the technical evidence needed to ensure AI capabilities are robust, secure, and fit-for-use over time.

Translational Medicine Discovery & Profiling (TMDP) is a group of physicians and clinical researchers who drive innovative science from discovery to the patient through the selection, profiling, and early clinical development of medicines. Medical directors oversee phase1 first in human (FiH) and phase2 proof of concept (PoC) and dose range finding (DRF) studies in support of Phase3 development. Medical directors in translational medicine are key and highly visible members of global cross functional project teams that design and implement early research and discovery projects. They collaborate with colleagues in biology and chemistry to identify targets in diseases with significant unmet medical needs, provide input on likely clinical development pathways, design clinical development plans in collaboration with late phase development, draft clinical trial protocols and serve as medical leads for these trials. As a Medical Director in Translational Medicine Gastroenterology, you will report to the TM Head. You will work closely with biomarker experts to implement programs, collaborate with research scientists to identify, develop and implement strategies for preclinical support of program objectives, and actively participate in Health Authority interactions. Key Responsibilities Lead global clinical trial teams through phase1 and 2 development Draft the early clinical development plan Act as medical lead for early clinical studies Represent the team in relevant decision boards Serve a primary contact for internal and external key opinion leaders Oversee publication and internal/external presentation of clinical study results Essential Requirements Medical doctor with board certification in gastroenterology Several years of clinical experience treating IBD (UC and CD) patients Ability to learn fast and work independently Ability to lead multidisciplinary teams in a matrix organization Excellent communication and presentation skills Desirable Requirements Research experience (e.g., Ph.D.) is a plus but not a strict requirement Drug development experience as trial investigator or pharma experience is a plus but not a strict requirement Publications in the field of IBD are a plus but not a strict requirement

Novartis Farmacéutica is seeking a Medical Director in Translational Medicine Gastroenterology in Greater London. This role involves leading global clinical trial teams, drafting early clinical development plans, and serving as a medical lead for clinical studies. The ideal candidate is a certified medical doctor with clinical experience in treating IBD patients and possesses excellent communication skills. Desirable qualifications include research experience or prior drug development involvement.

Monitoring - Functional Excellence Lead : London, United KingdomRemote (For those residing in the United Kingdom, but more than 50 miles from the office)Relocation Support: This role is based in London (The Westworks), United Kingdom or Remote, United Kingdom. Novartis is unable to offer relocation support: please only apply if accessible. Great clinical trials depend on exceptional monitoring, and this is your opportunity to help shape what that looks like across Novartis. As GCP Excellence Monitoring Lead, you will play a pivotal role in advancing innovative, data-driven monitoring approaches that improve trial quality, efficiency and patient outcomes. Working at the forefront of clinical operations transformation, you will drive monitoring excellence, champion adaptive monitoring practices, and influence how monitoring strategies are implemented across a global organisation. If you are passionate about innovation, continuous improvement and delivering operational impact at scale, this is an exciting opportunity to help redefine the future of clinical trial oversight.

Novartis is seeking a Monitoring - Functional Excellence Lead to drive data-driven monitoring across clinical trials from London (The Westworks) or remote in the UK. This role shapes adaptive monitoring strategies, delivering operational impact at scale and enhancing trial quality, efficiency and patient outcomes. As part of the GCP Excellence Monitoring team, you will champion innovative approaches, influence monitoring implementation globally, and partner with cross-functional teams to