Jazz Pharmaceuticals
Brief Description Reporting to Senior Director Global Network Planning. Responsible for managing the end to end supply chain for a portfolio of Jazz products, including planning, procurement, distribution in compliance with applicable GxP and other regulations. Creates the overall strategic plan for portfolio of products Represent SC on product/platform teams as required and lead the SC engagement with CMO sites and partners. Business process owner for Supply Chain for SAP MRP activities Lead and support other projects such as second sources, global expansion and new initiatives. Essential Functions/Responsibilities Responsible for end to end planning and supply of raw materials, intermediates, components and finished goods for portfolio of Jazz products. Creates the end to end plan and any relevant scenarios to mitigate the risk to supply Supports relationship management of key supply chain vendors. Lead the implementation and execution of Supply Chain systems and processes to manage the supply of product for patients. Creates and implements supply scenarios and strategies to support uninterrupted supply of product to patients. Supports the planning and scheduling of product with partners and internal sites , ensuring timely supply of compliant product to patients and achieving supply chain business objectives as required. Managing performance, relationships and improvements with supply chain manufacturing and distribution partners through regular, structured communication processes including face to face meetings as required. Develop and implement metrics to monitor and record, using appropriate systems, usage of critical raw materials, API/drug substance and finished products and ensuring accuracy of information to assist with supply chain decision making. Manage the relationship with commercial partners and other functions to understand and obtain demand forecasts. Develop and lead the S&OP, MRP and other supply management processes for relevant products to ensure patient supply. Responsible for supply chain compliance with GxP, trade, financial and other regulations to ensure continued patient supply. Identify, contribute to and lead projects with other functions (such as Tech Ops, QA, RA, Finance etc) as required to achieve supply chain objectives. Demonstrate Jazz management competencies (technical, planning, communication, interpersonal, leading, judgment skills). Required Knowledge, Skills, and Abilities High level of customer orientation/understanding Attention to detail and accuracy Ability to influence internal and external constituents Strong interpersonal and communication skills Accountable to meet goals and objectives
Brief Description Reporting to Senior Director Global Network Planning. Responsible for managing the end to end supply chain for a portfolio of Jazz products, including planning, procurement, distribution in compliance with applicable GxP and other regulations. Creates the overall strategic plan for portfolio of products Represent SC on product/platform teams as required and lead the SC engagement with CMO sites and partners. Business process owner for Supply Chain for SAP MRP activities Lead and support other projects such as second sources, global expansion and new initiatives. Essential Functions/Responsibilities Responsible for end to end planning and supply of raw materials, intermediates, components and finished goods for portfolio of Jazz products. Creates the end to end plan and any relevant scenarios to mitigate the risk to supply Supports relationship management of key supply chain vendors. Lead the implementation and execution of Supply Chain systems and processes to manage the supply of product for patients. Creates and implements supply scenarios and strategies to support uninterrupted supply of product to patients. Supports the planning and scheduling of product with partners and internal sites , ensuring timely supply of compliant product to patients and achieving supply chain business objectives as required. Managing performance, relationships and improvements with supply chain manufacturing and distribution partners through regular, structured communication processes including face to face meetings as required. Develop and implement metrics to monitor and record, using appropriate systems, usage of critical raw materials, API/drug substance and finished products and ensuring accuracy of information to assist with supply chain decision making. Manage the relationship with commercial partners and other functions to understand and obtain demand forecasts. Develop and lead the S&OP, MRP and other supply management processes for relevant products to ensure patient supply. Responsible for supply chain compliance with GxP, trade, financial and other regulations to ensure continued patient supply. Identify, contribute to and lead projects with other functions (such as Tech Ops, QA, RA, Finance etc) as required to achieve supply chain objectives. Demonstrate Jazz management competencies (technical, planning, communication, interpersonal, leading, judgment skills). Required Knowledge, Skills, and Abilities High level of customer orientation/understanding Attention to detail and accuracy Ability to influence internal and external constituents Strong interpersonal and communication skills Accountable to meet goals and objectives
Jazz Pharmaceuticals
Cambridge, Cambridgeshire
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Job Role: We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team. Key Responsibilities: Utilize modern molecular modelling methods to support different stages of R&D programs. Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates. Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables. Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours. Set the vision and strategy for computational chemistry. Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry. Manage CRO compchem activities, providing expertise and guidance. Present plans and results internally, including at board level, and externally at conferences. Contribute to the writing of patent applications, scientific publications, and internal reports. Develop and mentor less experienced staff. Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies. Undertake ongoing professional development by attending relevant training and conferences. Requirements & Qualifications: MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting. Expert knowledge in CADD software packages and modern molecular modelling techniques. Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies. Passion for drug discovery with a deep entrepreneurial and problem-solving attitude. Mastery of all the theoretical and practical principles of medicinal chemistry and drug design. Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process. In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems. Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame. Demonstrated track record of scientific publications. Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Job Role: We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team. Key Responsibilities: Utilize modern molecular modelling methods to support different stages of R&D programs. Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates. Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables. Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours. Set the vision and strategy for computational chemistry. Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry. Manage CRO compchem activities, providing expertise and guidance. Present plans and results internally, including at board level, and externally at conferences. Contribute to the writing of patent applications, scientific publications, and internal reports. Develop and mentor less experienced staff. Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies. Undertake ongoing professional development by attending relevant training and conferences. Requirements & Qualifications: MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting. Expert knowledge in CADD software packages and modern molecular modelling techniques. Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies. Passion for drug discovery with a deep entrepreneurial and problem-solving attitude. Mastery of all the theoretical and practical principles of medicinal chemistry and drug design. Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process. In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems. Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame. Demonstrated track record of scientific publications. Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Jazz Pharmaceuticals
Sittingbourne, Kent
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description To analyse and report on QC test samples (e.g. packaging items, raw materials, intermediates, finished products and stability samples) in accordance with cGMP. Essential Functions/Responsibilities Perform analytical testing using HPLC, GC, TLC, FTIR, UV and other required techniques in accordance with written procedures Provide clear and accurate records of all work performed Record data into appropriate records and notify management of any OOS, OOT, OOE or questionable results Ensures that all results are reported and approved in a timely manner Identifies any non-compliances or deviations and notifies management Ensures that all equipment is fully calibrated and serviced prior to testing Applies appropriate SOPs and test methods to all testing to ensure compliance and quality of resulting data Maintains a clean and tidy work environment, including carrying out housekeeping tasks as assigned Maintains stocks of consumables, chemicals, solvents, etc through regular stock checks and re-ordering when required Carries out checking of analytical documentation (where experience and training allows) Assists with sampling of raw material samples as required Actively looks for and implements improvements in productivity and efficiency within own work area Works in accordance with the systems in place with regards to health & safety, security and the environment Undertakes other activities, indirectly related or unrelated to the above listed accountabilities, as assigned by line manager Operates in accordance with the company corporate values of being patient driven, passionate, innovative, collaborative, accountable, having integrity and achieving excellence Required Knowledge, Skills, and Abilities Typically >1 year relevant post degree work experience, ideally in the Pharmaceutical, Biotechnology or a related industry Experience of using routine analytical instruments (e.g. HPLC, GC, TLC, FTIR, UV etc.) and of routine analytical techniques (titration, pipetting, etc) Working knowledge of office IT packages Good level of written and verbal communication skills Excellent attention to detail and 'concern for quality' Understanding of cGMP Required/Preferred Education and Licenses Bachelor's degree in science or related discipline Attributes and Behaviors Operates in accordance with the Jazz values of: Integrity: Walks the Talk. Honest, ethical and genuine in interactions and compliant in conduct. Provides transparent, open feedback and holds self and other accountable. Innovation: Challenges the Status Quo. Has an open, curious mindset. Takes educated risks and finds new ways to solve problems. Gets comfortable with failure. Recognizes wins and learns from mistakes. Anticipates future needs. Pursuit of Excellence: Makes an Impact. Is agile and adaptable to change. Continuously asks, "How can we make this better?". Acts and continuously iterates. Focuses on action, agile performance. Passion: Put Patients First, Always. Truly cares about what is done and consistently strives to do their best for our patients. Collaboration: Seeks Better Perspectives. Seeks new, diverse perspectives to drive better outcomes. Creates a safe space to share opinions. Partners with respect and takes accountability for actions. Celebrates our differences. Proven organisational and interpersonal skills, demonstrated through the following competencies: Customer Focus: Is dedicated to meeting the expectations and requirements of internal and external customers; gets first-hand customer information and uses it for improvements in products and services. Integrity and Trust: Is widely trusted; is seen as a direct, truthful individual; can present the unvarnished truth in an appropriate and helpful manner; doesn't misrepresent themselves for personal gain. Peer Relationships: Can quickly find common ground and solve problems for the good of all; can solve problems with peers with the minimum of noise; is seen as a team player and is cooperative. Managing through Systems: Can design practices, processes, and procedures that allow managing from a distance; is comfortable letting things manage themselves without intervening; can make things work through others, without being there; can impact people and results remotely. Problem Solving: uses rigorous logic and methods to solve difficult problems with effective solutions; probes all fruitful sources for answers; can see hidden problems; is excellent at honest analysis; looks beyond the obvious and doesn't stop at the first answers. Decision Quality: Makes good decisions based upon a mixture of analysis, wisdom, experience and judgement. Building Effective Teams: Blends people into teams when needed; creates strong morale and spirit in their team; shares wins and successes; lets people finish and be responsible for their work. Planning: Accurately scopes out length and difficulty of tasks and projects; sets objectives and goals; breaks down work into the process steps; develops scheduled and task/people assignments; anticipates and adjusts for problems and roadblocks; measures performance against goals; evaluates results. Priority Setting: Spends their time and the time of others on what's important; quickly zeros in on the critical few and puts the trivial many aside; creates focus. Negotiating: Can negotiate skillfully in tough situations with both internal and external groups; can settle differences with minimum noise; can win concessions without damaging relationships; can be both direct and forceful as well as diplomatic; gains trust quickly of other parties to the negotiations; has a good sense of timing. Self-development: Is personally committed and actively works to continuously improve themselves; understands that different situation and levels may call for different skills and approaches; works to deploy strengths; works on compensating for weakness and limits. Motivating Others: Creates a climate in which people want to do their best; can motivate many kinds of direct reports and team or project members; can assess each person's hot button and use it to get the best out of them; pushes tasks and decisions down; empowers others; invites input from each person and shares ownership and visibility; makes each individual feel their work is important; is someone people like working for and with. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description To analyse and report on QC test samples (e.g. packaging items, raw materials, intermediates, finished products and stability samples) in accordance with cGMP. Essential Functions/Responsibilities Perform analytical testing using HPLC, GC, TLC, FTIR, UV and other required techniques in accordance with written procedures Provide clear and accurate records of all work performed Record data into appropriate records and notify management of any OOS, OOT, OOE or questionable results Ensures that all results are reported and approved in a timely manner Identifies any non-compliances or deviations and notifies management Ensures that all equipment is fully calibrated and serviced prior to testing Applies appropriate SOPs and test methods to all testing to ensure compliance and quality of resulting data Maintains a clean and tidy work environment, including carrying out housekeeping tasks as assigned Maintains stocks of consumables, chemicals, solvents, etc through regular stock checks and re-ordering when required Carries out checking of analytical documentation (where experience and training allows) Assists with sampling of raw material samples as required Actively looks for and implements improvements in productivity and efficiency within own work area Works in accordance with the systems in place with regards to health & safety, security and the environment Undertakes other activities, indirectly related or unrelated to the above listed accountabilities, as assigned by line manager Operates in accordance with the company corporate values of being patient driven, passionate, innovative, collaborative, accountable, having integrity and achieving excellence Required Knowledge, Skills, and Abilities Typically >1 year relevant post degree work experience, ideally in the Pharmaceutical, Biotechnology or a related industry Experience of using routine analytical instruments (e.g. HPLC, GC, TLC, FTIR, UV etc.) and of routine analytical techniques (titration, pipetting, etc) Working knowledge of office IT packages Good level of written and verbal communication skills Excellent attention to detail and 'concern for quality' Understanding of cGMP Required/Preferred Education and Licenses Bachelor's degree in science or related discipline Attributes and Behaviors Operates in accordance with the Jazz values of: Integrity: Walks the Talk. Honest, ethical and genuine in interactions and compliant in conduct. Provides transparent, open feedback and holds self and other accountable. Innovation: Challenges the Status Quo. Has an open, curious mindset. Takes educated risks and finds new ways to solve problems. Gets comfortable with failure. Recognizes wins and learns from mistakes. Anticipates future needs. Pursuit of Excellence: Makes an Impact. Is agile and adaptable to change. Continuously asks, "How can we make this better?". Acts and continuously iterates. Focuses on action, agile performance. Passion: Put Patients First, Always. Truly cares about what is done and consistently strives to do their best for our patients. Collaboration: Seeks Better Perspectives. Seeks new, diverse perspectives to drive better outcomes. Creates a safe space to share opinions. Partners with respect and takes accountability for actions. Celebrates our differences. Proven organisational and interpersonal skills, demonstrated through the following competencies: Customer Focus: Is dedicated to meeting the expectations and requirements of internal and external customers; gets first-hand customer information and uses it for improvements in products and services. Integrity and Trust: Is widely trusted; is seen as a direct, truthful individual; can present the unvarnished truth in an appropriate and helpful manner; doesn't misrepresent themselves for personal gain. Peer Relationships: Can quickly find common ground and solve problems for the good of all; can solve problems with peers with the minimum of noise; is seen as a team player and is cooperative. Managing through Systems: Can design practices, processes, and procedures that allow managing from a distance; is comfortable letting things manage themselves without intervening; can make things work through others, without being there; can impact people and results remotely. Problem Solving: uses rigorous logic and methods to solve difficult problems with effective solutions; probes all fruitful sources for answers; can see hidden problems; is excellent at honest analysis; looks beyond the obvious and doesn't stop at the first answers. Decision Quality: Makes good decisions based upon a mixture of analysis, wisdom, experience and judgement. Building Effective Teams: Blends people into teams when needed; creates strong morale and spirit in their team; shares wins and successes; lets people finish and be responsible for their work. Planning: Accurately scopes out length and difficulty of tasks and projects; sets objectives and goals; breaks down work into the process steps; develops scheduled and task/people assignments; anticipates and adjusts for problems and roadblocks; measures performance against goals; evaluates results. Priority Setting: Spends their time and the time of others on what's important; quickly zeros in on the critical few and puts the trivial many aside; creates focus. Negotiating: Can negotiate skillfully in tough situations with both internal and external groups; can settle differences with minimum noise; can win concessions without damaging relationships; can be both direct and forceful as well as diplomatic; gains trust quickly of other parties to the negotiations; has a good sense of timing. Self-development: Is personally committed and actively works to continuously improve themselves; understands that different situation and levels may call for different skills and approaches; works to deploy strengths; works on compensating for weakness and limits. Motivating Others: Creates a climate in which people want to do their best; can motivate many kinds of direct reports and team or project members; can assess each person's hot button and use it to get the best out of them; pushes tasks and decisions down; empowers others; invites input from each person and shares ownership and visibility; makes each individual feel their work is important; is someone people like working for and with. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
