WISE Campaign

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme. We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work. Discover more about our company wide benefits and life at GSK on our webpage Life at GSK GSK. Associate Director, Decision Science for Clinical Operations This is an exciting opportunity to channel your passion for innovation in the field of Statistics and Data Science to help shape the future of the Biostatistics function and transform the way in which GSK uses data and quantitative thinking to drive decision making in R&D. Biostatistics is the single largest functional group of Statisticians, Programmers and Data Scientists within GSK R&D, numbering approx. 900 people in the US, UK, Europe and India. Our mission is to put statistical thinking at the heart of R&D decision making, to ensure that predictive models, well designed experiments, and trials deliver robust evidence as the input to those decisions, ultimately making the R&D process more efficient. We are investing in our cutting edge innovation capabilities by expanding the Statistics & Data Science Innovation Hub (SDS IH) led by Prof Nicky Best. The vision of SDS IH is to be the catalyst for innovation and advanced data driven decision making. In this role, you will work closely with SDS IH to embed sophisticated analytics into Global Clinical Operations (GCO), enabling stakeholders to make timely, robust, and impactful decisions. As the Associate Director of Decision Science for Clinical Operations, you will serve as a strategic thought partner to senior R&D leadership, architecting the future of how GSK plans and executes clinical trials. Your mission is to embed sophisticated analytics and data driven frameworks into the core of GCO. You will frame and model complex operational scenarios, quantify risks and trade offs, and challenge assumptions to discover and unlock added value for high impact R&D projects. By translating analytical insights into clear, actionable strategies, you will drive decision quality and accelerate the delivery of new medicines to patients. In this role you will be involved in: Strategic & Facilitative Leadership Partner with GCO's Decision Analytics team to lead high stakes strategic discussions with clinical development leadership to frame complex business problems, develop differentiated options, and define clear analytical pathways. Synthesize diverse evidence, including empirical data and expert judgment, to construct cohesive decision models that guide strategy. Influence key investment and operational decisions by translating complex model outputs into compelling narratives and actionable recommendations for executive audiences. Advanced Modeling & Analytics Implement advanced decision models to quantify risk and identify value add opportunities in study timelines and resource allocation. Deliver robust predictive models for critical operational challenges, including patient recruitment, site performance, and milestone attainment, to create value optimal and risk aware delivery strategies. Identify and champion non obvious value add opportunities by applying innovative analytical approaches to complex clinical operations challenges. Technical Innovation & Capability Development Drive the design and deployment of scalable analytics solutions, including production ready models, automated monitoring systems, and real time data pipelines. Champion best in class DevOps practices, including version control (Git), CI/CD pipelines, and automated testing to ensure robust, reproducible, and scalable solutions. Train and mentor colleagues on the use of tools, methods, and structured decision frameworks to build organisational capability. Basic Qualifications & Skills: PhD (preferred) in a quantitative field (e.g., Data Science, Statistics, Computer Science, Operations Research, Decision Analysis) or MSc with equivalent experience in the pharmaceutical or biotech industry. Proven expertise designing and building flexible decision models (e.g., Monte Carlo simulation, Bayesian analysis, scenario planning, sensitivity analysis) to quantify risk and value trade offs. Expertise in Python or R with the ability to adapt models. Knowledge of the drug development lifecycle and Clinical Operations workflows. Track record of leading and mentoring technical teams to deliver data science solutions with measurable business impact. Exceptional communication and influencing skills, with the ability to distil complex analyses into compelling recommendations for senior leadership in a matrix environment. Preferred Qualifications & Skills: Hands on experience with DevOps best practices, including Git, CI/CD, and testing. Therapeutic area depth, including knowledge of clinical development and trial design. Direct Clinical Operations experience. Decision Analysis or Management Consulting experience focused on pharmaceutical strategy or operations. Expertise in advanced methods such as Bayesian statistics, machine learning, and enrollment simulation. Closing Date for Applications 24th February 2026 When applying for this role, please use the cover letter of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D. GSK Why GSK? GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders, and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, colour, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the Link where you will find answers to multiple questions we receive. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf . click apply for full job details

Job description Site Name: UK London New Oxford Street, Stevenage, USA - Pennsylvania - Upper Providence Posted Date: Feb We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme. We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work. Discover more about our company wide benefits and life at GSK on our webpage Life at GSK. Statistics Leader / Associate Director Oncology Statistics You will lead statistical planning and delivery across clinical programs and contribute to clinical developments plans within oncology. You will work closely with clinical, regulatory, safety, data science and commercial teams. You will design robust clinical trials and analyses that shape development decisions and regulatory strategy. You will drive methodological innovation and mentor colleagues. Join us to grow your career, make a real impact on patient-focused R&D, and help unite science, technology and talent to get ahead of disease together. Key Responsibilities Provide statistical support to Projects across Oncology pipeline Lead statistical design, analysis and interpretation for clinical programs across development phases using a wide range of statistical approaches (e.g. Bayesian methodology) Use simulations and advanced statistical methodology to inform trial design and risk assessment. Review and contribute to statistical analysis plans, protocols and regulatory submissions. Work with cross-functional teams to translate statistical insight into program strategy. Mentor and coach statisticians to build capability and quality. Why you? Basic Qualifications & Skills We are looking for professionals with these required skills to achieve our goals: Advanced degree in Statistics, Biostatistics or related quantitative discipline (MSc or equivalent) with significant relevant post graduate experience, in oncology, within the pharmaceutical industry or a clinical research setting. Proven track record contributing statistical expertise to early and/or late phase clinical development. Practical experience implementing simulations and statistical methods using R, Python or similar tools. Clear written and verbal communication skills for explaining methods and results to non statistical colleagues. Strong organisation and time management across multiple projects and deadlines Preferred Qualifications & Skills Please note the following skills are not necessary, just preferred, if you do not have them, please still apply: PhD in Statistics, Biostatistics, or closely related field. Experience with Bayesian methods, adaptive trial designs, and advanced modelling. Experience applying statistical methods to disease modelling, high dimensional data, or real world evidence. Experience mentoring or leading small technical teams. Experience preparing regulatory documents and interacting with regulators. Comfortable working in high performance computing or large simulation environments. Closing Date for Applications 4th March 2026 Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the Link where you will find answers to multiple questions we receive. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at

A global biopharma company is seeking a Statistics Leader / Associate Director to lead statistical planning and delivery for oncology programs. The ideal candidate will possess an advanced degree in Statistics and significant experience within the pharmaceutical industry. Responsibilities include designing clinical trials, mentoring colleagues, and working with cross-functional teams. Competitive salary, hybrid work options, and a bonus based on company performance are part of the offering.

Job description Site Name: USA - Pennsylvania - King of Prussia, Belgium-Wavre, Field Worker - SWE, France - Evreux, Singapore - Tuas, UK London New Oxford Street, USA - Pennsylvania - Marietta Posted Date: Feb Business Introduction We make and supply medicines and vaccines all around the globe and our teams own every production stage, from creating quality products at our manufacturing sites to designing effective supply forecasting and regulatory inspections; all powered by digital, data and analytics. We operate at impressive scale, producing over 2.3 billion packs of medicines and doses of vaccines in 2023. We continue to modernize, so we can launch even more new products at speed whilst continuing to deliver across our entire portfolio through our relentless focus on quality, safety, and service. The way we work will change. For some, the shift in technology and products will be revolutionary. Our R&D pipeline demands a new kind of supply chain, and we need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients. Position Summary The Director of Cost and Risk Management plays a strategic leadership role within the Project Controls organization, overseeing cost engineering, financial governance, and risk management across a portfolio of Global capital projects. This role ensures that projects are delivered within budget and risk thresholds while maintaining compliance with GMP and corporate standards. The ideal candidate brings deep expertise in cost control, risk analytics, and stakeholder engagement, with a proven track record in the pharmaceutical or life sciences sector. This role will directly report to the Head of Project Controls (PC) and will be part of Global project controls leadership, which manages both project-based PC deliveries and functional responsibilities for key processes within GCP. In this role you will be responsible for: Cost Management Leadership Develop and implement cost control strategies across global capital projects. Translate Capital management principles into Cost management functional practices (such as Accruals, Cashflows, Value of work done etc.). Oversee budgeting, forecasting, cost tracking, and variance analysis. Ensure alignment with corporate financial policies and capital governance processes. Lead cost benchmarking and value engineering initiatives. Support with Independent Project reviews. Risk Management Strategy Establish and maintain a robust project risk management framework. Facilitate risk identification, qualitative and quantitative analysis, and mitigation planning. Integrate risk insights into project decision-making and portfolio prioritization. Lead risk workshops and scenario planning with cross-functional teams. Responsible for Quantitative Risk analysis using tools Support with Independent Project reviews. Governance & Reporting Ensure adherence to internal controls, audit requirements, and regulatory standards Support stage-gate reviews and SCRB (Supply chain review board) presentations. Deliver executive-level reporting on cost performance, risk exposure, and mitigation effectiveness. Develop dashboards and analytics tools to support proactive decision-making. Support portfolio-level financial and risk reporting. Leadership & Collaboration Lead a team of cost engineers, risk analysts, and project controls professionals. Collaborate with Finance, Engineering, Quality, Procurement, and PMO teams. Act as a senior advisor to project sponsors and executive leadership. Project Management Framework (PMF) Tools & Templates Prepare and maintain all tools and templates related to Cost management (Cost report, Cashflows, Prepare and maintain all tools and templates related to Risk management (Risk Register, Develop dashboards and analytics tools to support proactive decision-making. Drive continuous improvement in cost and risk management practices GCP Operations budget Prepare, update & maintain GCP Operations budget Monthly actuals reconciliation, department budget tracking, Why You? Basic Qualification Bachelor's or master's degree in engineering, Finance, Project Management, or related field. 15+ years of experience in project controls, with leadership in cost and risk management. knowledge of comprehensive stage gate models for capital project delivery through all stages of the project lifecycle. knowledge of Cost Management and Risk management practices for capital projects. Experience with Senior stakeholder management and influencing capabilities Experience with tools such as SAP, EcoSys, Unifier and risk modelling software Safran). Experience with data analysis, statistical analysis and report preparation. Preferred Qualification Please note the following skills are not necessary, just preferred, if you do not have them, please still apply: MSc or PhD or other Chartered / Professional Qualification in a relevant discipline Excellent management, communication and interpersonal skills, with comfort cooperating with individuals internally and externally at all organizational levels. Understanding of how different functions interface on GSK projects. Solid knowledge of GSK project process, User requirement management, quality and compliance requirement, site project completion and pre-start processes, and how these impact engineering and design, construction, commissioning, and qualification contracts Familiar with the GCP Project Management Framework (PMF), relevant engineering standards and compliance requirement as well as Quality Management Systems PMP (Project Management Professional) or CCP (Certified Cost Professional) or PMI-SP (Scheduling Professional) or Lean Six Sigma or similar process improvement credentials Work Arrangement Hybrid arrangements will be considered depending on site needs and role responsibilities. Regular on-site presence will be required to collaborate with project and site teams. How to apply If you are ready to lead cost and risk practices that improve project outcomes and support meaningful work for patients, we want to hear from you. Please submit your CV and a short note describing your relevant experience and what motivates you to apply. We welcome applicants from all backgrounds and encourage people who value inclusion to apply. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call. Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK . click apply for full job details

A global biopharma company is seeking a Director of Cost and Risk Management to oversee cost engineering and financial governance across global capital projects. The ideal candidate will have over 15 years of experience in project controls, a strong understanding of cost management practices, and proven leadership in risk management. The role requires collaboration with cross-functional teams and involves reporting on cost performance and risk mitigation strategies. This position offers a hybrid work arrangement, requiring regular on-site presence.

Job description Site Name: USA - Pennsylvania - Upper Providence, UK London New Oxford Street, USA - Massachusetts - Boston Posted Date: Feb At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D About RIIRU The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two fold. The remit of RIIRU is to identify novel targets based on human genetics, develop assets for clinical studies, and perform trials through to submission for approvals. This goal is enabled through strategic external (e.g., Flagship Pioneering, Vesalius, Muna Therapeutics and others) and GSK internal partnerships (Research Technologies). PLEASE NOTE: This career opportunity requires an on site office presence (minimum of two days a week) at one of GSK's US (PA or MA) or UK (Stevenage or London HQ) sites. Position Summary A Senior Scientific Director, Clinical Development is sought to provide clinical and scientific leadership for potential new, established and emerging indications for assets in clinical development with a strong focus in respiratory disease. You will work with project teams to plan and ensure delivery of clinical research and development activities and establish efficient collaboration throughout all stages of development. You will report to the Vice President, Clinical Research Head, Respiratory. This role is pivotal in driving GSK's mission to deliver transformative medicines to patients, ensuring clinical excellence, regulatory compliance, and operational efficiency. The successful candidate will not only deliver results but also inspire and empower teams to achieve exceptional outcomes. Lead the clinical development strategy from a drug or program including accountability for the clinical components of the Target Medicine Profile (TMP) and leadership of the clinical matrix team (CMT). Ensure cohesive and comprehensive clinical development plans (CDP) for product(s) and/or indication(s). Identify and highlight transformational opportunities where projects can offer highly significant benefit to patients. Contribute to development of the Integrated Evidence Strategy (IES), including oversight of the CDP and its component clinical trials. Integrate scientific rationale, regulatory requirements, product development plans, and commercial goals to optimize asset indications and programs, providing strategic leadership in assuring that clinical study designs are aligned with the IES and CDP. Drive ambitious and achievable clinical development timelines, incorporating key decision points, risk and cost analyses, and Go/No Go criteria. Lead and be accountable for the evaluation of the probability of technical success (PTRS) of clinical studies/programs. Assess risk/benefit at the study and/or project level and take action to mitigate risk where appropriate. Nurture and maintain relationships with counterparts in Commercial, Regulatory, Clinical Operations, Medical Affairs, and Statistics. Serve as a clinical point of contact for senior management and senior level matrix teams, across the internal matrix and positively interface and influence a broad range of external experts (e.g., regulators, payors, CROs, consultants, investigators). Lead clinical development discussions and teams at global regulatory interactions. Make substantial contributions to global regulatory submissions/files (e.g., IND, NDA, BLA, MAA), including briefing documents, presentations, and responses to regulatory questions. Manage technical and leadership development of Clinical Development staff via direct line management, mentoring and coaching across the organisation. Manage and contribute to the development of strategic initiatives, specific business development activities including due diligence, and organisational initiatives in Clinical Development, championing innovative methodologies and processes including digital tools and technology, encouraging others to think differently and adopt new ways of working. Stay abreast of advancements in therapeutic area research, clinical trial methodologies, competitive environment, and regulatory space to maintain GSK's competitive edge. Excel in ambiguous situations by demonstrating strong problem solving skills and innovative thinking. Anticipate potential challenges, develop strategic approaches, and effectively communicate uncertainty to stakeholders while guiding teams through unclear circumstances. Adept at identifying opportunities for synergy and innovation across the organisation and influencing others to adopt an enterprise mindset. Use strategic thinking to analyze, interpret, and critically evaluate complex data and information. Anticipate obstacles and identify innovative solutions to ensure timely delivery of evidence that supports regulatory approvals and patient benefit. Skilled in understanding individual motivations and tailoring approaches to team members to drive commitment, a strong track record of inspiring and leading others to achieve exceptional results. Navigate ambiguity by anticipating regulatory challenges and proactively addressing issues. Basic Qualifications Advanced Degree Required: PhD or PharmD Minimum of 5 years of experience in Respiratory clinical research and development, may include postgrad experience. Minimum of 3 years of experience of contributing to or leading a global clinical development program in the biopharmaceutical industry. Experience working with global regulatory agencies and managing global clinical trials in respiratory disease Preferred Qualifications MD preferred but not required Proven track record of successfully leading cross functional teams and executing industry sponsored clinical trials. In depth knowledge of regulatory requirements, Good Clinical Practice (GCP), and ethical guidelines for clinical research. Demonstrated ability to work independently to design trials to regulatory standards from concept to completion. Demonstrated leadership/People Management experience in clinical practice, academia and/or industry, leading line and matrix teams with a reputation of inspiring and motivating high performance. Experience in setting and executing scientific strategy preferred. Experience in translational medicine preferred. Experience in leading NDA, BLA, or MAA submissions preferred. Salary and Compensation If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $242,550 to $404,250. If you are based in another US location, the annual base salary range is $220,500 to $367,500. US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call. Please note should your inquiry not relate to adjustments . click apply for full job details

Job description Site Name: UK - Hertfordshire - Stevenage, GSK HQ, USA - Massachusetts - Waltham, USA - Pennsylvania - Upper Providence Posted Date: Feb Business Introduction At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D Position Summary The Respiratory, Immunology and Inflammation Translational Unit (RIITU), within RIIRU therapy area is accountable for end-to-end disease area translational science to inform therapy area and program level biomarker strategies (from preclinical to launch) to increase the probability of success from preclinical to clinical transitions and enable earlier and higher confidence asset related decisions. This includes generation of foundational data as well as disease biomarker development and validation that allow timely deployment of tools/biomarkers to support Proof of Mechanism (PoM), signs of clinical efficacy, Proof of Concept (PoC), and pairing Mechanisms of Action (MoAs) with patient subtypes to predict responder populations. We are looking for a dynamic individual to excel in the following responsibilities. Key Responsibilities Disease Biomarker Strategy Development and Delivery Partner with the Clinical Teams, Research Technologies and the Development organization with focus on Respiratory portfolio to identify, establish biomarkers for decision making throughout clinical development phases and aligned with the overall research and development goals. This will include the identification, prioritization and validation of disease relevant biomarkers, mechanistic/surrogate biomarkers, patient stratification, and differentiated response prediction, their deployment into clinical studies and interpretation of data/results. Translational Leadership Provide strategic leadership contributing to deep understanding of Disease areas enabling the development and execution of translational research disease strategies to support the discovery and development of novel differentiated therapeutics including evaluation and diligence of business development opportunities. Translational Innovation Evaluate novel techniques and technologies (i.e. spatial transcriptomics) to inform translational initiatives, biomarker development and validation working in collaboration with platform teams and within a multi-functional matrix environment. Identify and guide validation of human assays (cells, tissues and organs) to enhance human translation and predictive value through the application of resources such as the Human Cell Atlas, disease tissue multi-omics data and genetic resources (external or proprietary). Cross functional Collaboration Collaborate closely with cross functional teams including the Translational, Disease Teams, Human Genetics & Genomics, biology groups, biomarker platforms, Medicine Development Teams, HBSM, data sciences, regulatory affairs, business development and commercial to ensure seamless integration of translational research and biomarker strategies across the drug development lifecycle. External Partnerships Establish and maintain strategic collaborations with academic institutions, contract research organizations (CROs), and other external partners to access cutting edge technologies, tools, reagents, biosamples, biomarker expertise, and research capabilities. Foster a network of external experts and key opinion leaders to stay at the forefront of translational science and biomarker advancements across the industry. Contribute to evaluation and diligence of business development opportunities. Matrix Leadership Provide mentorship, guidance, and professional development opportunities to ensure a high performing and motivated team. Manage disease and project level resources, budgets, and timelines to ensure the successful execution of projects and achievement of milestones and RITU objectives. Represent RITU at portfolio governance reviews providing critical input to pipeline and investment decision making. Why You? Basic Qualification Ph.D. in a relevant scientific discipline (e.g., Cell/Molecular Biology, Genetics, Pharmacology, Physical Chemistry or related field) Extensive experience in translational science and biomarker development ideally within the pharmaceutical or biotechnology industry. Recognised translational/biomarker expert in scientific community through publications and contributions to the field. Experience of translation and biomarkers implementation in Respiratory indications Experience of working in a clinical trial setting, working as part of a clinical study and experience of authoring and oversight of clinical and regulatory documents Preferred Qualification Knowledge of regulatory requirements, industry standards, best practices and compliance considerations in Translational Research and biomarker development and validation. Broad knowledge in technologies and methods used in translational research. Proven track record of program decision making through implementing biomarker strategies and delivering translational science insights in support of drug progression through clinical transition milestones. Experience leading/managing external collaborations and evaluation of business development opportunities. Strong management skills, with the ability to prioritize and manage multiple objectives to meet timelines while maintaining attention to detail and high-performance standards. Excellent inclusive matrix leadership skills, with the ability to create psychological safety, inspire and motivate a team towards achieving common goals. Working Model This role is based in the United Kingdom or the United States and follows a hybrid working model. You will be expected to work on site regularly to collaborate with your team and partners. How to apply If this role inspires you, please apply with your CV and a short cover note describing a recent translational achievement. Tell us what you did, why it mattered, and the impact it had. We welcome people from all backgrounds and value inclusion in how we hire and lead. We look forward to hearing from you. If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $189,750 to $316,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. Salary ranges may not be displayed in the job posting for a specific country; the relevant compensation will be discussed during the recruitment process. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. Equal Opportunity Employer GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Agility of Work Culture We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Adjustments Please note if your enquiry is related to adjustments you can contact to request a call. We will not be able to support you through these channels if your enquiry does not relate to adjustments. We have created a Recruitment FAQ guide. Click the link for answers to multiple questions we receive. . click apply for full job details

Job description Site Name: USA - Massachusetts - Waltham, GSK HQ, UK - Hertfordshire - Stevenage, USA - Pennsylvania - Upper Providence Posted Date: Feb GSK is seeking a highly skilled Vice President, Medicine Development Leader (MDL), to strategically lead the optimal global development of a renal medicine at an asset level, acting as the single point of accountability for the medicine from clinical Proof of Concept (PoC) to Approval in the first major market(s). By working with the various stakeholders across GSK's Medicine Development matrix (R&D, Manufacturing, Commercial, etc.), you will define the strategic vision and operational plan for the medicine, aligning it with the overall organizational strategy. You will create and lead the matrixed Medicine Development Team (MDT), which is responsible for representing the various disciplines required to optimally deliver the development of the medicine including Clinical Development, Medical, Commercial and Manufacturing, amongst others. The Vice President, MDL reports to the SVP & Head Advanced Pipeline Unit- Respiratory, Immunology and Inflammation Research Unit. About RIIRU The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. Our core therapeutic areas include Respiratory, Hepatology, Nephrology, Neurodegeneration and Rheumatology. The remit of RIIRU is to identify novel targets based on human genetics, develop assets for clinical studies, and perform trials through to submission for approvals. This goal is enabled through strategic external (e.g., Flagship Pioneering, Vesalius, Muna Therapeutics and others) and GSK-internal partnerships (Research Technologies). PLEASE NOTE This career opportunity requires an on site office presence (minimum of two days a week) in one of GSK's US(PA or MA) or UK (London - New Oxford Street or Stevenage) sites. Key Responsibilities Act as a single point of accountability in GSK for all aspects of a medicine being developed globally, from proof of clinical activity (POC) to Approval in all major market(s) Work closely with the Early Development Lead (EDL) and Medicine Commercial Lead (MCL) to ensure a smooth transition of the lead indication(s) from the EDL upon achievement of clinical PoC and to the MCL upon Approval in first major market(s) Post approval, provide key support to the Medicine Commercial Team (MCT) in the first major markets ensuring the MDT provides optimal support to registration, including Post Marketing Requirements (PMRs) and life cycle management (LCM) in the major markets Work with the functional line Heads supporting RIIRU to select MDT members and lead this multi disciplinary matrix team, supporting differentiated development for team members, owning the performance of the MDT and partnering with Line Managers to drive performance Partner with the Pipeline Project Manager (PPM), energize and motivate the MDT to drive a high performing team and operational delivery of the project, including setting team objectives to ensure successful project delivery, including options for acceleration, parallel indication development and smart risk taking. Partner with R&D Business Development, leading the development planning for a prospective in licensed asset by bringing together input from the relevant functions and TA experts to develop a Medicine Profile (MP) and development plans including but not limited to clinical feasibility, regulatory planning and CMC risk mitigation Leads the cross functional MDT to: Establish a compelling vision for the medicine and Target Medicine Profile (TMP) which positions the medicine within the R&D strategy taking the competitive landscape into account, translating GSK's strategy into asset strategy and actionable plans for multiple areas or functions Deliver differentiated medicines of value for patients, stakeholders and markets through an evidence package that supports regulatory approval, market access and the product's life cycle Prioritize and maximize the asset's development options including developing multiple indications Partner with the Global Medical Lead (GML) and MCL to develop an indication expansion and LCM plan for the asset. Make clear evidence based go / no go / accelerate decisions and identify clear inflection points, based on results Ensure excellence in execution of all governance processes, including MDT members, on oversight of clinical studies, patient safety & pharmacovigilance, scientific engagement and promotional practices Enhance patient focus by incorporating the voice of the patient into development plans Increase visibility amongst the external communities to bring medical solutions to patients with unmet medical needs Embed core processes including cost efficiency, adoption of new technology, risk identification & management, compliance with policy Promote organizational reputation and drives asset value by engaging and negotiating with internal and external stakeholders Ensures quality & compliance oversight in line with R&D expectations and project needs; ensures quality of data and science Serves as the asset's single point of contact and spokesperson to Senior Management, senior boards, other relevant internal governance committees and external Advisory Committees, as needed Delivers and manages the asset resourcing plan (people & finances), including serving as the single point for accountability for managing the asset budget to the agreed variance, working closely with the PPM and Finance Partner to do so Basic Qualifications Advanced degree including MD, PhD, PharmD, MBA, MS Drug development expertise in the global pharmaceutical/biotechnology industry Filing experience with BLA/NDA/MAA submissions as a core responsibility Experience in the entirety of drug development across the R&D/commercial life cycle including Discovery, late stage Development, Regulatory, Manufacturing Medical and Commercial Experience in product development and/or commercialization, in late phase development (from clinical PoC onwards), clinical trial management, post approval studies, regulatory and manufacturing compliance Experience leading teams in a complex, matrixed, global and multi disciplinary organization with high accountability, minimal authority and multiple lines of reporting Experience working with regulators and with regulatory requirements including legal and government frameworks within and across global geographies Experience creating the strategy for pre and post marketing studies and driving the lifecycle process Experience building budgets and leading the strategic and budget planning process Experience the healthcare environment, and access in all major markets Preferred Qualifications Highly developed ethics and integrity, with demonstrated ethical medical decision making skills Strong matrix leadership and motivational skills Ability to work collaboratively and successfully across functions Research, Commercial, Regulatory, Global Medicine Supply, Legal, regions etc. Compensation & Benefits If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $242,250 to $403,750. The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. Contact & Adjustments Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call. Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However . click apply for full job details