Make your mark for patients We are looking for a Senior Scientist - Antibody Production who is highly motivated, curious and meticulous to join us in our Antibody Production team, based in our office in Slough, Berkshire, UK. About the role You will form part of a multi-disciplinary team generating antibody and antibody related proteins to support new drug candidate discovery and development. As a laboratory-based research scientist, you will be responsible for key aspects in the production, characterisation, logistics management and long-term storage of high-quality antibodies. You will therefore contribute to the progression of molecules from the earliest stages of drug discovery all the way to drug candidate. Who you'll work with You will work in the Antibody and Novel Therapeutics department alongside some of the world's very best antibody communities and antibody experts within a diverse, engaged and scientifically vibrant team all working towards the same goal. What you'll do Purify, analyse and share/store high-purity antibodies destined for use in pre-clinical projects and in supporting studies for later stage/clinical antibody projects. Liaise with project leads and antibody engineers to understand, capture and prioritise antibody reagent requests. Be the owner of and curate a purified antibody reagent database and liaise with colleagues requiring samples and information across Research and Early Clinical Development. Generate, analyse, interrogate, and document data using electronic lab notebooks and sample management/registration systems. Communicate data through project presentations and written reports, including more formal documentation when related to clinical phase projects or external collaborators and service providers. Innovate or identify and implement new and relevant technologies for capacity or technology expansion. Interested? For this role we're looking for the following education, experience and skills A BSc graduate with a demonstrable knowledge of and experience with proteins and antibodies (MSc/PhD or industrial experience in a relevant biological discipline may be advantageous). Experienced in purification techniques and use of purification platforms (e.g. Affinity chromatography, IEX, HIC, SEC, AKTA). Detailed, broad knowledge and experience of antibody purification methods: chromatography, resins, buffer condition and the impact of production scale. Practical experience with analytical assays for characterisation, purity and biophysical understanding of proteins/antibodies. Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you! About us UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science. Why work with us? At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow and have the freedom to carve your own career path to achieve your full potential. UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on . Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Jul 03, 2025
Full time
Make your mark for patients We are looking for a Senior Scientist - Antibody Production who is highly motivated, curious and meticulous to join us in our Antibody Production team, based in our office in Slough, Berkshire, UK. About the role You will form part of a multi-disciplinary team generating antibody and antibody related proteins to support new drug candidate discovery and development. As a laboratory-based research scientist, you will be responsible for key aspects in the production, characterisation, logistics management and long-term storage of high-quality antibodies. You will therefore contribute to the progression of molecules from the earliest stages of drug discovery all the way to drug candidate. Who you'll work with You will work in the Antibody and Novel Therapeutics department alongside some of the world's very best antibody communities and antibody experts within a diverse, engaged and scientifically vibrant team all working towards the same goal. What you'll do Purify, analyse and share/store high-purity antibodies destined for use in pre-clinical projects and in supporting studies for later stage/clinical antibody projects. Liaise with project leads and antibody engineers to understand, capture and prioritise antibody reagent requests. Be the owner of and curate a purified antibody reagent database and liaise with colleagues requiring samples and information across Research and Early Clinical Development. Generate, analyse, interrogate, and document data using electronic lab notebooks and sample management/registration systems. Communicate data through project presentations and written reports, including more formal documentation when related to clinical phase projects or external collaborators and service providers. Innovate or identify and implement new and relevant technologies for capacity or technology expansion. Interested? For this role we're looking for the following education, experience and skills A BSc graduate with a demonstrable knowledge of and experience with proteins and antibodies (MSc/PhD or industrial experience in a relevant biological discipline may be advantageous). Experienced in purification techniques and use of purification platforms (e.g. Affinity chromatography, IEX, HIC, SEC, AKTA). Detailed, broad knowledge and experience of antibody purification methods: chromatography, resins, buffer condition and the impact of production scale. Practical experience with analytical assays for characterisation, purity and biophysical understanding of proteins/antibodies. Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you! About us UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science. Why work with us? At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow and have the freedom to carve your own career path to achieve your full potential. UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on . Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Make your mark for patients We are looking for a Regulatory CMC Scientist to join our Global Regulatory team, based in any of our Brussels (Belgium), Slough (UK), or Atlanta (US) offices. About the role Define the strategy, planning, and preparation (writing and review) of CMC submission documentation for regulatory submissions (new marketing applications, variations) from a global/regional perspective to achieve timely approvals and meet business needs. Who you'll work with You will work within the Regulatory CMC team and collaborate with other technical functions across the business. What you'll do Provide regulatory CMC leadership on cross-functional sub teams (Global Regulatory Affairs (GRA) Teams and Technical Teams) and advise on best practices. Contribute to and ensure adequate provision of regulatory CMC input for all Health Authority (HA) interactions on CMC matters across regions. Communicate CMC regulatory strategy, risks, and overall plans effectively to GRA Teams, Technical, Development, and Commercial Teams. Highlight critical issues arising during the product lifecycle to senior management promptly for stakeholder communication. Lead or contribute to process improvements and departmental initiatives within the CMC Regulatory Affairs function, including SOP reviews, digital strategies, and tools. Qualifications, experience, and skills Bachelor's degree; Master's preferred in life sciences or related fields. Significant experience in pharmaceutical Regulatory Affairs CMC, manufacturing, analytical development, quality assurance/control, or related technical fields, or as a regulatory authority reviewer. Proven success in authoring and delivering CMC sections for marketing authorizations of biological or chemical entities. Knowledge of GMP standards and change management systems. Interest or experience in digitalization, data management, or AI. Strong teamwork, communication, and leadership skills, with ability to operate in a matrix organization. If you want to learn more about R&D at UCB, please visit R&D at UCB . Are you ready to 'go beyond' to create value and make your mark for patients? If so, we would love to hear from you! About us UCB is a global biopharmaceutical company focused on neurology and immunology, with around 8,500 employees worldwide, driven by science and inspired by patients. Why work with us? At UCB, we create value through collaboration and innovation. Our inclusive culture fosters growth and career development, with a focus on making a positive impact for patients, employees, and the planet. Join us to grow and pursue your full potential. UCB is an equal opportunity employer. All employment decisions are made without regard to characteristics protected by law. For accommodations during the application process, contact . Please note this channel is for accommodation requests only.
Jul 03, 2025
Full time
Make your mark for patients We are looking for a Regulatory CMC Scientist to join our Global Regulatory team, based in any of our Brussels (Belgium), Slough (UK), or Atlanta (US) offices. About the role Define the strategy, planning, and preparation (writing and review) of CMC submission documentation for regulatory submissions (new marketing applications, variations) from a global/regional perspective to achieve timely approvals and meet business needs. Who you'll work with You will work within the Regulatory CMC team and collaborate with other technical functions across the business. What you'll do Provide regulatory CMC leadership on cross-functional sub teams (Global Regulatory Affairs (GRA) Teams and Technical Teams) and advise on best practices. Contribute to and ensure adequate provision of regulatory CMC input for all Health Authority (HA) interactions on CMC matters across regions. Communicate CMC regulatory strategy, risks, and overall plans effectively to GRA Teams, Technical, Development, and Commercial Teams. Highlight critical issues arising during the product lifecycle to senior management promptly for stakeholder communication. Lead or contribute to process improvements and departmental initiatives within the CMC Regulatory Affairs function, including SOP reviews, digital strategies, and tools. Qualifications, experience, and skills Bachelor's degree; Master's preferred in life sciences or related fields. Significant experience in pharmaceutical Regulatory Affairs CMC, manufacturing, analytical development, quality assurance/control, or related technical fields, or as a regulatory authority reviewer. Proven success in authoring and delivering CMC sections for marketing authorizations of biological or chemical entities. Knowledge of GMP standards and change management systems. Interest or experience in digitalization, data management, or AI. Strong teamwork, communication, and leadership skills, with ability to operate in a matrix organization. If you want to learn more about R&D at UCB, please visit R&D at UCB . Are you ready to 'go beyond' to create value and make your mark for patients? If so, we would love to hear from you! About us UCB is a global biopharmaceutical company focused on neurology and immunology, with around 8,500 employees worldwide, driven by science and inspired by patients. Why work with us? At UCB, we create value through collaboration and innovation. Our inclusive culture fosters growth and career development, with a focus on making a positive impact for patients, employees, and the planet. Join us to grow and pursue your full potential. UCB is an equal opportunity employer. All employment decisions are made without regard to characteristics protected by law. For accommodations during the application process, contact . Please note this channel is for accommodation requests only.
Make your mark for patients We are looking for a Value Based Partnering (VBP) Lead who is a dynamic transformative leader to join us in our PIM Payer and ISEG Operations team, based in our office in Slough, UK. About the role: The Payer and ISEG Operations team is a key element of operationalizing the evolution of our operating model. This team will be the interface between the Asset Teams and Countries to ensure that the Countries are fully empowered to achieve UCB's growth ambition. Who you'll work with: The Value Based Partnering Lead will work with the Asset, Country and Regional teams. What you'll do: Set VBP ambition, with internal / external KPIs defined and tracked Develop VBP access strategic / application framework Contribute to VBP Corporate narrative Develop PI VBP strategic agenda, supporting PI drivers and projects to enable PI VBP Develop VBP ideation / application tools, frameworks and processes aligned to business priorities (eg contracting framework, financial modelling, toolboxes, data platforms, governance) Empower implementors via training, experience sharing and project pilots Integrate with strategic account excellence and account-based marketing Support strategic account identification, cross functional goal alignment and planning, strategic account planning excellence for long-term partnership, and competitor insight excellence Interested? For this role we're looking for the following education, experience and skills. Experience in value based partnering and contracting Experience in account management Bachelor's Degree Required Stakeholder Management and Influence: Ability to build and nurture trusted relationships with key stakeholders across Countries and Global, facilitating collaborations and alignment on strategic objectives. Strategic Thinking: Capacity to understand the implications of value based partnering, anticipate how this is integrated within market trends and align to UCB strategies, overarching business goals and approach Execution excellence: Ability to build and implement pragmatic & effective frameworks, templates & processes that maximize impact and optimize for seamless performance Change Management: Ability to anticipate implications of new ways of working, and maintain focus on strategic priorities and highest impact Innovative design thinking: innovative mindset taking into account novel ways of implementing VBP Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you! About us UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science. Why work with us? At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential. As an Equal Opportunity Employer, we are open to all talent, and adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on for application to US based roles. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Jul 01, 2025
Full time
Make your mark for patients We are looking for a Value Based Partnering (VBP) Lead who is a dynamic transformative leader to join us in our PIM Payer and ISEG Operations team, based in our office in Slough, UK. About the role: The Payer and ISEG Operations team is a key element of operationalizing the evolution of our operating model. This team will be the interface between the Asset Teams and Countries to ensure that the Countries are fully empowered to achieve UCB's growth ambition. Who you'll work with: The Value Based Partnering Lead will work with the Asset, Country and Regional teams. What you'll do: Set VBP ambition, with internal / external KPIs defined and tracked Develop VBP access strategic / application framework Contribute to VBP Corporate narrative Develop PI VBP strategic agenda, supporting PI drivers and projects to enable PI VBP Develop VBP ideation / application tools, frameworks and processes aligned to business priorities (eg contracting framework, financial modelling, toolboxes, data platforms, governance) Empower implementors via training, experience sharing and project pilots Integrate with strategic account excellence and account-based marketing Support strategic account identification, cross functional goal alignment and planning, strategic account planning excellence for long-term partnership, and competitor insight excellence Interested? For this role we're looking for the following education, experience and skills. Experience in value based partnering and contracting Experience in account management Bachelor's Degree Required Stakeholder Management and Influence: Ability to build and nurture trusted relationships with key stakeholders across Countries and Global, facilitating collaborations and alignment on strategic objectives. Strategic Thinking: Capacity to understand the implications of value based partnering, anticipate how this is integrated within market trends and align to UCB strategies, overarching business goals and approach Execution excellence: Ability to build and implement pragmatic & effective frameworks, templates & processes that maximize impact and optimize for seamless performance Change Management: Ability to anticipate implications of new ways of working, and maintain focus on strategic priorities and highest impact Innovative design thinking: innovative mindset taking into account novel ways of implementing VBP Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you! About us UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science. Why work with us? At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential. As an Equal Opportunity Employer, we are open to all talent, and adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on for application to US based roles. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Make your mark for patients We are looking for an enthusiastic and experienced Mass Spectrometrist to join our Protein Structure and Biophysics department, located in Slough, UK. About the role This laboratory-based position requires expertise in the acquisition and interpretation of peptide mapping and intact protein mass spectrometry data to provide structural characterisation of our therapeutic antibody molecules. Who you'll work with The Mass Spectrometry team supports New Biological Entity (NBE) and New Chemical Entity (NCE) discovery from pre-portfolio investigation through to candidate selection within a department which incorporates cryo-EM, X-ray crystallography, NMR and SAXS, alongside the protein production group. This role involves working closely with the MS team, the Protein Structure & Biophysics department and several groups in UK and global discovery. What you'll do Perform analysis of antibody therapeutics using mass spectrometric techniques Generate critical data to support candidate progression and selection Clearly communicate MS data on diverse antibody formats to multiple project teams Maintain accurate records and contribute to comprehensive data packages Identify and implement new technologies and methodologies Mentor other members of the MS team Ensure lab equipment is properly maintained and initiate appropriate repair and maintenance. Interested? For this role we're looking for the following experience and skills PhD and/or several years industrial laboratory-based experience in protein and peptide mass spectrometric analysis of antibodies and target proteins Hands-on experience and responsibility for Thermo Orbitrap / Tribrid and Waters instrumentation coupled to nanoflow and microflow UPLC systems Peptide mapping expertise Use of data analysis software packages for sequence mapping and intact mass deconvolution e.g. Protein Metrics Byos, BioPharma Finder, Proteome Discoverer or similar Appreciation of antibody and protein expression systems and purification protocols Managing or mentoring junior scientists within an MS environment Troubleshooting and maintenance of LC-MS systems Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you! About us UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science. Why work with us? At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential. UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on . Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Feb 12, 2025
Full time
Make your mark for patients We are looking for an enthusiastic and experienced Mass Spectrometrist to join our Protein Structure and Biophysics department, located in Slough, UK. About the role This laboratory-based position requires expertise in the acquisition and interpretation of peptide mapping and intact protein mass spectrometry data to provide structural characterisation of our therapeutic antibody molecules. Who you'll work with The Mass Spectrometry team supports New Biological Entity (NBE) and New Chemical Entity (NCE) discovery from pre-portfolio investigation through to candidate selection within a department which incorporates cryo-EM, X-ray crystallography, NMR and SAXS, alongside the protein production group. This role involves working closely with the MS team, the Protein Structure & Biophysics department and several groups in UK and global discovery. What you'll do Perform analysis of antibody therapeutics using mass spectrometric techniques Generate critical data to support candidate progression and selection Clearly communicate MS data on diverse antibody formats to multiple project teams Maintain accurate records and contribute to comprehensive data packages Identify and implement new technologies and methodologies Mentor other members of the MS team Ensure lab equipment is properly maintained and initiate appropriate repair and maintenance. Interested? For this role we're looking for the following experience and skills PhD and/or several years industrial laboratory-based experience in protein and peptide mass spectrometric analysis of antibodies and target proteins Hands-on experience and responsibility for Thermo Orbitrap / Tribrid and Waters instrumentation coupled to nanoflow and microflow UPLC systems Peptide mapping expertise Use of data analysis software packages for sequence mapping and intact mass deconvolution e.g. Protein Metrics Byos, BioPharma Finder, Proteome Discoverer or similar Appreciation of antibody and protein expression systems and purification protocols Managing or mentoring junior scientists within an MS environment Troubleshooting and maintenance of LC-MS systems Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you! About us UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science. Why work with us? At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential. UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on . Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.