Director, Program Management Germany About Tubulis Tubulis is dedicated to developing novel, effective, and safe therapies for the treatment of cancer - one of the most pressing challenges in modern medicine. Our mission is to become a leading company in targeted therapeutics and antibody-drug conjugates (ADCs). With a passionate team, proprietary technologies, and innovative therapeutic concepts, we are ushering in a new era in the fight against cancer. Join a multidisciplinary, highly focused group working to deliver promising ADCs to patients with solid and haematological cancers. Position Overview We are seeking a proactive and committed Director, Program Management to provide strategic leadership and operational excellence for TUB-040, Tubulis' lead program, as well as for our portfolio of innovative therapeutic programs spanning early- and late-stage clinical development. The Director will partner closely with leaders in Clinical Development, Regulatory, CMC, Biomarkers, PK, Nonclinical, Commercial, and other functions to ensure timely delivery of key milestones, robust risk management, and smooth progression of programs toward regulatory approval and commercialization. The role reports to the Vice President, Program Management. Key Responsibilities Lead the cross-functional TUB-040 program team through all stages of clinical development - from IND-enabling studies to pivotal trials and regulatory submissions. Serve as the primary point of contact for program strategy, planning, execution, and milestone delivery. Develop and maintain integrated program plans, budgets, timelines, and risk management strategies aligned with corporate objectives. Partner with functional leaders (Clinical Development, Clinical Operations, Regulatory, CMC, Biostatistics, Biomarkers, Commercial, etc.) to ensure requirements are well-defined, resourced, and executed with quality. Drive effective decision-making by preparing clear program updates and recommendations for governance committees. Provide mentorship within the Program Management function, fostering process improvements and building organizational capabilities. Encourage collaboration, guide team members, address challenges, and promote a positive working environment. Maintain open communication with the VP Program Management, team members, partners, and key stakeholders. Candidate Profile Bachelor's or advanced degree in a relevant scientific discipline. 10+ years of experience in the biotechnology or pharmaceutical industry, with significant program/project management leadership. Demonstrated success advancing programs through multiple phases of clinical development (IND/CTA, Phase I-III, BLA/MAA, launch, lifecycle management). Proven expertise in late-stage development and pivotal trials. Comprehensive knowledge of clinical development, regulatory requirements, GxP, CMC, nonclinical, and commercialization aspects. Strong leadership, organizational, and interpersonal skills with the ability to inspire and motivate cross-functional teams. Excellent communication and presentation skills; able to synthesize complex data and present compelling updates to leadership and stakeholders. Proficiency with project management tools (MS Project, Excel, PowerPoint, Think-Cell). Self-starter with strong problem-solving skills; comfortable working in a fast-paced, dynamic environment. Fluent English (written and spoken); German is a plus. Why Join Us Flat hierarchies and short decision-making processes. Open corporate culture with mobile working options. Unlimited contract following probation, plus 30 days of vacation. Mobility allowance, modern technology, and a pleasant office environment. Strong team spirit, appreciation of individual contributions, and regular team events. Work alongside a multicultural, global team passionate about advancing next-generation cancer therapies.
Nov 15, 2025
Full time
Director, Program Management Germany About Tubulis Tubulis is dedicated to developing novel, effective, and safe therapies for the treatment of cancer - one of the most pressing challenges in modern medicine. Our mission is to become a leading company in targeted therapeutics and antibody-drug conjugates (ADCs). With a passionate team, proprietary technologies, and innovative therapeutic concepts, we are ushering in a new era in the fight against cancer. Join a multidisciplinary, highly focused group working to deliver promising ADCs to patients with solid and haematological cancers. Position Overview We are seeking a proactive and committed Director, Program Management to provide strategic leadership and operational excellence for TUB-040, Tubulis' lead program, as well as for our portfolio of innovative therapeutic programs spanning early- and late-stage clinical development. The Director will partner closely with leaders in Clinical Development, Regulatory, CMC, Biomarkers, PK, Nonclinical, Commercial, and other functions to ensure timely delivery of key milestones, robust risk management, and smooth progression of programs toward regulatory approval and commercialization. The role reports to the Vice President, Program Management. Key Responsibilities Lead the cross-functional TUB-040 program team through all stages of clinical development - from IND-enabling studies to pivotal trials and regulatory submissions. Serve as the primary point of contact for program strategy, planning, execution, and milestone delivery. Develop and maintain integrated program plans, budgets, timelines, and risk management strategies aligned with corporate objectives. Partner with functional leaders (Clinical Development, Clinical Operations, Regulatory, CMC, Biostatistics, Biomarkers, Commercial, etc.) to ensure requirements are well-defined, resourced, and executed with quality. Drive effective decision-making by preparing clear program updates and recommendations for governance committees. Provide mentorship within the Program Management function, fostering process improvements and building organizational capabilities. Encourage collaboration, guide team members, address challenges, and promote a positive working environment. Maintain open communication with the VP Program Management, team members, partners, and key stakeholders. Candidate Profile Bachelor's or advanced degree in a relevant scientific discipline. 10+ years of experience in the biotechnology or pharmaceutical industry, with significant program/project management leadership. Demonstrated success advancing programs through multiple phases of clinical development (IND/CTA, Phase I-III, BLA/MAA, launch, lifecycle management). Proven expertise in late-stage development and pivotal trials. Comprehensive knowledge of clinical development, regulatory requirements, GxP, CMC, nonclinical, and commercialization aspects. Strong leadership, organizational, and interpersonal skills with the ability to inspire and motivate cross-functional teams. Excellent communication and presentation skills; able to synthesize complex data and present compelling updates to leadership and stakeholders. Proficiency with project management tools (MS Project, Excel, PowerPoint, Think-Cell). Self-starter with strong problem-solving skills; comfortable working in a fast-paced, dynamic environment. Fluent English (written and spoken); German is a plus. Why Join Us Flat hierarchies and short decision-making processes. Open corporate culture with mobile working options. Unlimited contract following probation, plus 30 days of vacation. Mobility allowance, modern technology, and a pleasant office environment. Strong team spirit, appreciation of individual contributions, and regular team events. Work alongside a multicultural, global team passionate about advancing next-generation cancer therapies.
Job Title: Project Procurement Lead Contract Type: Contract (with potential permanent conversion) Experience Level: 10-15 years Industry Background: FMCG, Pharmaceuticals, or Chemicals Role Overview The Project Procurement Lead will manage procurement activities for major investment projects and coordinate planning and execution at the site. This role carries strategic responsibility for procuring goods and services for the construction of manufacturing, laboratory, and office facilities, with project values ranging between £5 million and £500 million. Key Responsibilities Develop and implement Procurement Execution Strategy for assigned projects. Own end-to-end commercial activities, including procurement, expediting, contract management, and contract close-out. Manage procurement across: Goods: Process and electrical equipment, AHUs, black utilities (pumps, valves), lab equipment, furniture, consumables, automation systems, and spare parts. Services: Construction, piping, HVAC, electrical, cleanroom fit-out, consulting, engineering, and planning. Actively manage the Procurement Master Plan (PMP) during project execution, ensuring timely reporting and proactive risk mitigation. Collaborate closely with stakeholders, including: Internal procurement teams (buyers, order managers, contract managers). Procurement management & category management. Project directors, engineers, and SMEs. Support functions (Quality, EHS, Legal, Finance, HR). External collaborators (EPCM, EPC, main trade and equipment suppliers). Key Requirements 10+ years' experience in CAPEX project/procurement management (pharma/biotech preferred). Proven experience in plant construction, procurement, sales, and contract management. Strong track record with large CAPEX projects (£5m-£500m). Fluent in English; German is an advantage. Team-oriented with excellent communication skills; able to thrive in matrix and interdisciplinary environments. Strong commercial acumen, with analytical thinking and problem-solving ability. Resilient, adaptable, and proactive in fast-paced environments. Technical training (ETH/FH) in process, chemical, mechanical, civil, or plant engineering is an advantage. Must-have: Procurement leadership on large-scale CAPEX projects, ideally within the pharmaceutical sector.
Nov 09, 2025
Full time
Job Title: Project Procurement Lead Contract Type: Contract (with potential permanent conversion) Experience Level: 10-15 years Industry Background: FMCG, Pharmaceuticals, or Chemicals Role Overview The Project Procurement Lead will manage procurement activities for major investment projects and coordinate planning and execution at the site. This role carries strategic responsibility for procuring goods and services for the construction of manufacturing, laboratory, and office facilities, with project values ranging between £5 million and £500 million. Key Responsibilities Develop and implement Procurement Execution Strategy for assigned projects. Own end-to-end commercial activities, including procurement, expediting, contract management, and contract close-out. Manage procurement across: Goods: Process and electrical equipment, AHUs, black utilities (pumps, valves), lab equipment, furniture, consumables, automation systems, and spare parts. Services: Construction, piping, HVAC, electrical, cleanroom fit-out, consulting, engineering, and planning. Actively manage the Procurement Master Plan (PMP) during project execution, ensuring timely reporting and proactive risk mitigation. Collaborate closely with stakeholders, including: Internal procurement teams (buyers, order managers, contract managers). Procurement management & category management. Project directors, engineers, and SMEs. Support functions (Quality, EHS, Legal, Finance, HR). External collaborators (EPCM, EPC, main trade and equipment suppliers). Key Requirements 10+ years' experience in CAPEX project/procurement management (pharma/biotech preferred). Proven experience in plant construction, procurement, sales, and contract management. Strong track record with large CAPEX projects (£5m-£500m). Fluent in English; German is an advantage. Team-oriented with excellent communication skills; able to thrive in matrix and interdisciplinary environments. Strong commercial acumen, with analytical thinking and problem-solving ability. Resilient, adaptable, and proactive in fast-paced environments. Technical training (ETH/FH) in process, chemical, mechanical, civil, or plant engineering is an advantage. Must-have: Procurement leadership on large-scale CAPEX projects, ideally within the pharmaceutical sector.
Principal Scientist - Non-Clinical PKPD (Contract) UK (Slough-based, VDI only - remote access provided) 12-month contract Full-time (37.5 hrs/week) £35.20-£47.92/hr (PAYE/LTD/Umbrella) We are supporting a global biopharma organisation seeking an experienced Principal Scientist, Non-Clinical PKPD to join their Early Clinical Development & Translational Sciences group on a 12-month contract . This role sits within the Quantitative Clinical Pharmacology function, which integrates PK/PD, systems modelling, clinical pharmacology, and DMPK approaches across the full drug development lifecycle. The position offers an excellent opportunity for a skilled pharmacokinetics/pharmacodynamics scientist to contribute to innovative drug development projects from preclinical through regulatory submission. Key Responsibilities Lead strategy and execution of non-clinical PKPD and GLP toxicokinetic studies. Provide scientific input into study protocols and regulatory study designs. Collaborate cross-functionally with Non-Clinical Safety, Bioanalysis, Clinical Pharmacology, and external CRO partners. Ensure delivery of high-quality data packages that meet GLP and regulatory submission standards. Analyse, interpret, and report PKPD/toxicokinetic study results; deliver reports and summaries for regulatory submissions. Effectively communicate interim and final results to project teams and stakeholders. Represent the function internally and externally, contributing to scientific reputation and best practices. Candidate Profile PhD, MSc, or BSc in pharmacology, quantitative pharmacology, pharmacokinetics/pharmacodynamics, DMPK, or related field. 5+ years' hands-on PKPD data analysis experience within pharma or CRO environments. Strong knowledge of pharmacology and drug mechanisms. Proven ability to design and deliver non-clinical PKPD studies and GLP toxicokinetics reports. Proficiency with Phoenix WinNonlin is essential; experience with modelling/simulation tools (e.g., Berkeley Madonna, R) a plus. Track record of regulatory submissions and/or scientific publications desirable. Strong communication skills with the ability to influence and collaborate in a matrix environment. Contract Details Duration: 12 months (potential extension). Hours: 37.5 per week (7.5 per day). Location: UK-based; virtual desktop infrastructure (VDI only). Candidate provides own equipment. Future office relocation to Surrey anticipated in 2026/27.
Nov 08, 2025
Full time
Principal Scientist - Non-Clinical PKPD (Contract) UK (Slough-based, VDI only - remote access provided) 12-month contract Full-time (37.5 hrs/week) £35.20-£47.92/hr (PAYE/LTD/Umbrella) We are supporting a global biopharma organisation seeking an experienced Principal Scientist, Non-Clinical PKPD to join their Early Clinical Development & Translational Sciences group on a 12-month contract . This role sits within the Quantitative Clinical Pharmacology function, which integrates PK/PD, systems modelling, clinical pharmacology, and DMPK approaches across the full drug development lifecycle. The position offers an excellent opportunity for a skilled pharmacokinetics/pharmacodynamics scientist to contribute to innovative drug development projects from preclinical through regulatory submission. Key Responsibilities Lead strategy and execution of non-clinical PKPD and GLP toxicokinetic studies. Provide scientific input into study protocols and regulatory study designs. Collaborate cross-functionally with Non-Clinical Safety, Bioanalysis, Clinical Pharmacology, and external CRO partners. Ensure delivery of high-quality data packages that meet GLP and regulatory submission standards. Analyse, interpret, and report PKPD/toxicokinetic study results; deliver reports and summaries for regulatory submissions. Effectively communicate interim and final results to project teams and stakeholders. Represent the function internally and externally, contributing to scientific reputation and best practices. Candidate Profile PhD, MSc, or BSc in pharmacology, quantitative pharmacology, pharmacokinetics/pharmacodynamics, DMPK, or related field. 5+ years' hands-on PKPD data analysis experience within pharma or CRO environments. Strong knowledge of pharmacology and drug mechanisms. Proven ability to design and deliver non-clinical PKPD studies and GLP toxicokinetics reports. Proficiency with Phoenix WinNonlin is essential; experience with modelling/simulation tools (e.g., Berkeley Madonna, R) a plus. Track record of regulatory submissions and/or scientific publications desirable. Strong communication skills with the ability to influence and collaborate in a matrix environment. Contract Details Duration: 12 months (potential extension). Hours: 37.5 per week (7.5 per day). Location: UK-based; virtual desktop infrastructure (VDI only). Candidate provides own equipment. Future office relocation to Surrey anticipated in 2026/27.
Role: Forward Deployed Engineer Location: Remote (UK) Summary: We are working with a Palantir Strategic Partner experiencing significant global demand for their expertise. They are expanding their team and looking for exceptional individuals to help deliver transformative data solutions. This is not a standard opportunity - it's a chance to work within one of the most exciting and high-growth spaces in the Palantir ecosystem, surrounded by some of the brightest minds in the industry. The Opportunity Work on cutting-edge Palantir Foundry projects with world-class clients across multiple sectors. Collaborate with senior experts and thought leaders in the Palantir ecosystem. Flexible routes of engagement: full-time employment, contract, or fractional models. Primarily remote work, with opportunities to travel and meet clients onsite. A culture that values partnership - every voice matters and every idea is heard. Key Responsibilities Design, build, and deliver Palantir Foundry solutions that address complex business challenges. Collaborate with cross-functional teams to deliver measurable business outcomes. Act as a trusted advisor to clients, ensuring solutions are practical, scalable, and impactful. Contribute to the continuous growth and innovation of the business. Requirements (Typical Profile) Strong experience with Palantir Foundry (modules such as Ontology, Workshop, Contour, Quiver, or pipelines). Background in data engineering, analytics, or software development. Proven ability to engage with clients in a consultative, solutions-focused way. Excellent problem-solving skills and communication abilities. A collaborative mindset and willingness to share knowledge. Why Join? Competitive compensation with flexibility on engagement model. Exposure to global projects in industries such as life sciences, energy, and finance. A culture built on collaboration, trust, and innovation. The chance to shape the future of data transformation, not just be part of it. If you are interested in joining a team at the forefront of Palantir-driven innovation, please get in touch to discuss this opportunity further. We are interested in talking to candidates who are interested in permanent full time engagements, as well as contractors.
Oct 30, 2025
Full time
Role: Forward Deployed Engineer Location: Remote (UK) Summary: We are working with a Palantir Strategic Partner experiencing significant global demand for their expertise. They are expanding their team and looking for exceptional individuals to help deliver transformative data solutions. This is not a standard opportunity - it's a chance to work within one of the most exciting and high-growth spaces in the Palantir ecosystem, surrounded by some of the brightest minds in the industry. The Opportunity Work on cutting-edge Palantir Foundry projects with world-class clients across multiple sectors. Collaborate with senior experts and thought leaders in the Palantir ecosystem. Flexible routes of engagement: full-time employment, contract, or fractional models. Primarily remote work, with opportunities to travel and meet clients onsite. A culture that values partnership - every voice matters and every idea is heard. Key Responsibilities Design, build, and deliver Palantir Foundry solutions that address complex business challenges. Collaborate with cross-functional teams to deliver measurable business outcomes. Act as a trusted advisor to clients, ensuring solutions are practical, scalable, and impactful. Contribute to the continuous growth and innovation of the business. Requirements (Typical Profile) Strong experience with Palantir Foundry (modules such as Ontology, Workshop, Contour, Quiver, or pipelines). Background in data engineering, analytics, or software development. Proven ability to engage with clients in a consultative, solutions-focused way. Excellent problem-solving skills and communication abilities. A collaborative mindset and willingness to share knowledge. Why Join? Competitive compensation with flexibility on engagement model. Exposure to global projects in industries such as life sciences, energy, and finance. A culture built on collaboration, trust, and innovation. The chance to shape the future of data transformation, not just be part of it. If you are interested in joining a team at the forefront of Palantir-driven innovation, please get in touch to discuss this opportunity further. We are interested in talking to candidates who are interested in permanent full time engagements, as well as contractors.
Position Principal Statistician and Methodological Lead - Digital Health and AI Clinical Trials Location: London, UK (with flexible hybrid working options) Contract: Full-time, permanent, competitive salary The Opportunity We are seeking a Principal Statistician and Methodological Lead to drive innovation at the forefront of AI-enabled digital clinical trials. This high-impact role offers a unique opportunity to shape methodological strategies for some of the most ambitious global health research initiatives ever undertaken. You will play a pivotal role in leading the design, analysis, and integration of cutting-edge methodologies across AI, biostatistics, and clinical epidemiology, with a focus on transforming health outcomes through advanced digital trial frameworks. Partnering with leading experts from academia, healthcare, and technology sectors, you'll help redefine how clinical trials are conducted on a global scale. About the Role This is a senior leadership position that combines visionary methodology development with hands-on trial design and analysis for decentralised and remote clinical studies. With a focus on leveraging AI and machine learning alongside classical statistical approaches, you'll help overcome the challenges of real-world data collection, participant adherence, and global trial scalability. As the methodological lead, you will: Define and lead the statistical and data science frameworks for large-scale observational and interventional clinical studies. Develop and implement strategies for AI-integrated, decentralised trial models that meet the highest ethical, regulatory, and data governance standards. Collaborate with international academic, clinical, and industry partners to create impactful, translational health interventions. Mentor rising researchers and statistical experts, building capacity in advanced methodologies across a global interdisciplinary team. Publish high-impact research and contribute to best-practice guidelines and policy development, establishing international benchmarks in digital and AI-enabled trials. What You'll Bring We are looking for experienced and forward-thinking individuals with: A PhD in statistics, biostatistics, epidemiology, health data science, or a related discipline. Internationally recognised expertise in developing methodologies for digital health, AI-enabled trials, or related fields. Experience leading large-scale observational or interventional health studies, ideally with an emphasis on machine learning or AI integration. A strong record of impactful peer-reviewed publications and research funding success. Proven leadership and mentoring capabilities, with experience managing statistical teams or interdisciplinary collaborations. Familiarity with regulatory and ethical frameworks governing digital health and AI research, such as GDPR, GCP, and AI ethics. Expertise working with complex health datasets, such as mobile health apps, wearables, or electronic health records (EHR). Why Consider This Role? This is an exceptional opportunity to: Take a leadership role in a world-class research initiative focused on AI and digital health innovation. Shape the future of global healthcare through novel methodologies in decentralised clinical trials. Partner with leading experts across health, technology, and academia. Play a pivotal role in transforming health outcomes for underserved populations, with a focus on advancing precision medicine and digital health interventions. You'll be stepping into a resource-rich environment backed by long-term funding and committed to delivering breakthroughs in personalised healthcare. Make a Lasting Impact Today This role offers you the chance to influence global healthcare standards while working at the frontier of AI-enabled clinical research. If you want to lead transformative work that shapes the future of medicine, apply now.
Oct 29, 2025
Full time
Position Principal Statistician and Methodological Lead - Digital Health and AI Clinical Trials Location: London, UK (with flexible hybrid working options) Contract: Full-time, permanent, competitive salary The Opportunity We are seeking a Principal Statistician and Methodological Lead to drive innovation at the forefront of AI-enabled digital clinical trials. This high-impact role offers a unique opportunity to shape methodological strategies for some of the most ambitious global health research initiatives ever undertaken. You will play a pivotal role in leading the design, analysis, and integration of cutting-edge methodologies across AI, biostatistics, and clinical epidemiology, with a focus on transforming health outcomes through advanced digital trial frameworks. Partnering with leading experts from academia, healthcare, and technology sectors, you'll help redefine how clinical trials are conducted on a global scale. About the Role This is a senior leadership position that combines visionary methodology development with hands-on trial design and analysis for decentralised and remote clinical studies. With a focus on leveraging AI and machine learning alongside classical statistical approaches, you'll help overcome the challenges of real-world data collection, participant adherence, and global trial scalability. As the methodological lead, you will: Define and lead the statistical and data science frameworks for large-scale observational and interventional clinical studies. Develop and implement strategies for AI-integrated, decentralised trial models that meet the highest ethical, regulatory, and data governance standards. Collaborate with international academic, clinical, and industry partners to create impactful, translational health interventions. Mentor rising researchers and statistical experts, building capacity in advanced methodologies across a global interdisciplinary team. Publish high-impact research and contribute to best-practice guidelines and policy development, establishing international benchmarks in digital and AI-enabled trials. What You'll Bring We are looking for experienced and forward-thinking individuals with: A PhD in statistics, biostatistics, epidemiology, health data science, or a related discipline. Internationally recognised expertise in developing methodologies for digital health, AI-enabled trials, or related fields. Experience leading large-scale observational or interventional health studies, ideally with an emphasis on machine learning or AI integration. A strong record of impactful peer-reviewed publications and research funding success. Proven leadership and mentoring capabilities, with experience managing statistical teams or interdisciplinary collaborations. Familiarity with regulatory and ethical frameworks governing digital health and AI research, such as GDPR, GCP, and AI ethics. Expertise working with complex health datasets, such as mobile health apps, wearables, or electronic health records (EHR). Why Consider This Role? This is an exceptional opportunity to: Take a leadership role in a world-class research initiative focused on AI and digital health innovation. Shape the future of global healthcare through novel methodologies in decentralised clinical trials. Partner with leading experts across health, technology, and academia. Play a pivotal role in transforming health outcomes for underserved populations, with a focus on advancing precision medicine and digital health interventions. You'll be stepping into a resource-rich environment backed by long-term funding and committed to delivering breakthroughs in personalised healthcare. Make a Lasting Impact Today This role offers you the chance to influence global healthcare standards while working at the frontier of AI-enabled clinical research. If you want to lead transformative work that shapes the future of medicine, apply now.