UKRI is seeking a lead researcher to drive projects at the MRC Laboratory of Molecular Biology in Cambridge. The successful candidate will conduct cutting-edge research in non-protein ubiquitylation, guiding the strategic direction and managing a team. The role entails significant responsibilities including training, mentoring, and securing funding. Candidates should possess a PhD and extensive postdoctoral experience, with a strong record of publications in the field.
May 31, 2026
Full time
UKRI is seeking a lead researcher to drive projects at the MRC Laboratory of Molecular Biology in Cambridge. The successful candidate will conduct cutting-edge research in non-protein ubiquitylation, guiding the strategic direction and managing a team. The role entails significant responsibilities including training, mentoring, and securing funding. Candidates should possess a PhD and extensive postdoctoral experience, with a strong record of publications in the field.
Overall purpose To lead on a range of projects within the group of Felix Randow at the MRC Laboratory of Molecular Biology (LMB), as part of an overall programme on cell autonomous immunity. Inspired ideas for research for the duration of the post in the context of the work of the division. To play a major role in the work of the research group, through the conduct of research, introduction of new ideas, dissemination of research results, support and training of others. Contribute to the strategic development of the group and of the division overall. To be a focus of expertise on non protein ubiquitylation and RZ family E3 ligases. Main duties Under the general leadership of the Group Leader, to be responsible for all aspects of the research projects, including defining the direction of the work, conducting the research, analysing the data, preparing the work for publication and disseminating the results at meetings. To present your work at seminars within the laboratory and at external meetings. To contribute to laboratory wide discussions on developments within the laboratory, particularly in the use of new techniques or new equipment. To contribute to the overall preparation of research for publication. To disseminate research findings in the form of publications, presentations, and reports and thus support the QQR mission of the division. To identify, develop and apply a broad range of techniques to pursue the research objectives. To keep up to date with developments in the field, proposing or implementing changes of direction as necessary. To train students, Postdoctoral Scientist and others and line manage group members where appropriate. To contribute to the MRC's engagement with the public and in the translation of research findings into improvements in health care. Key responsibilities The key responsibility is to undertake cutting edge research, aimed at key questions within the remit of the research group. You will be expected to provide the intellectual energy and independent thinking necessary to deliver the research and to play a major role in shaping the overall aims and success of the group. You will be expected to have the skill and understanding to be able to act independently in solving problems, many of which may require novel approaches. This will require the integration of different activities to ensure the successful delivery of the research projects. To introduce and apply new techniques across a wide range of disciplines and to have the creativity and initiative to develop novel approaches. To interact effectively with a wide range of staff, students and others to ensure the smooth running of the research group. This will include setting an example in the effective use of resources, training others in methods and use of equipment and taking responsibility for the use of communal facilities. To take on responsibility for managing equipment. To write scientific papers and to present at internal meetings and at conferences. To ensure the research is conducted in accordance with good practice and in compliance with local policies and legal requirements. To recognise opportunities for the creation of intellectual property and to cooperate in patent protection and in exploitation. To secure appropriate external funding and hence staffing and resources for the project, to include preparing grant applications for external funding and developing protocols. To manage existing collaborations, and establish new collaborations, both within the division and the LMB and with external establishments. To have a broad, balanced and informed perspective of current scientific issues especially those pertaining directly to the area of non protein ubiquitylation in the context of infection and cellular homeostasis. To agree the overall strategic direction of your research. You will be expected to take managerial and budgetary responsibility for your research projects, especially the procurement of external funding. Line management responsibilities will be undertaken; these responsibilities, to include staff development and performance management, should be applied in accordance with the MRC's policies and procedures. Training will be given if necessary. Working relationships You will report to Dr Randow and will liaise with other Research Support staff, Postdoctoral Scientists and students, not only in your group, but also across the LMB and with external collaborators. Additional Information The successful applicant must be available to start work no later than 01 July 2026. Person Specification Academic qualifications and experience: PhD in a relevant biological subject. Extensive postdoctoral research experience in non protein ubiq itylation in the context of infection and cellular homeostasis, PROTACs and manipulation of E3 ligase specificity. Technical skills and expertise: Significant experience of and proven expertise in cutting edge research relevant to the project, and knowledge of the field. Particularly useful would be experience in protein purification and the reconstitutions of reactions in vitro. Track record of research: This will include discoveries and significant achievements, and published papers preferably first author. Other relevant evidence of: Independent working and decision making Excellent standards of research conduct Mentoring Originality Influencing skills Communication skills Leadership Intellectual Property Corporate Responsibilities You must at all times carry out your responsibilities with due regard to the UKRI: Code of Conduct Equality, Diversity and Inclusion policy Health and Safety policy Data Protection policy Job descriptions should be reviewed on a regular basis and at the annual appraisal. Any changes should be made and agreed between you and your manager. The above lists are not exhaustive and you are required to undertake such duties as may reasonably be requested within the scope of the post. All employees are required to act professionally, co operatively and flexibly in line with the requirements of the post, the MRC and UKRI. The role holder will be required to have the appropriate level of security screening/vetting required for the role. UKRI reserves the right to run or re run security clearance as required during the course of employment.
May 31, 2026
Full time
Overall purpose To lead on a range of projects within the group of Felix Randow at the MRC Laboratory of Molecular Biology (LMB), as part of an overall programme on cell autonomous immunity. Inspired ideas for research for the duration of the post in the context of the work of the division. To play a major role in the work of the research group, through the conduct of research, introduction of new ideas, dissemination of research results, support and training of others. Contribute to the strategic development of the group and of the division overall. To be a focus of expertise on non protein ubiquitylation and RZ family E3 ligases. Main duties Under the general leadership of the Group Leader, to be responsible for all aspects of the research projects, including defining the direction of the work, conducting the research, analysing the data, preparing the work for publication and disseminating the results at meetings. To present your work at seminars within the laboratory and at external meetings. To contribute to laboratory wide discussions on developments within the laboratory, particularly in the use of new techniques or new equipment. To contribute to the overall preparation of research for publication. To disseminate research findings in the form of publications, presentations, and reports and thus support the QQR mission of the division. To identify, develop and apply a broad range of techniques to pursue the research objectives. To keep up to date with developments in the field, proposing or implementing changes of direction as necessary. To train students, Postdoctoral Scientist and others and line manage group members where appropriate. To contribute to the MRC's engagement with the public and in the translation of research findings into improvements in health care. Key responsibilities The key responsibility is to undertake cutting edge research, aimed at key questions within the remit of the research group. You will be expected to provide the intellectual energy and independent thinking necessary to deliver the research and to play a major role in shaping the overall aims and success of the group. You will be expected to have the skill and understanding to be able to act independently in solving problems, many of which may require novel approaches. This will require the integration of different activities to ensure the successful delivery of the research projects. To introduce and apply new techniques across a wide range of disciplines and to have the creativity and initiative to develop novel approaches. To interact effectively with a wide range of staff, students and others to ensure the smooth running of the research group. This will include setting an example in the effective use of resources, training others in methods and use of equipment and taking responsibility for the use of communal facilities. To take on responsibility for managing equipment. To write scientific papers and to present at internal meetings and at conferences. To ensure the research is conducted in accordance with good practice and in compliance with local policies and legal requirements. To recognise opportunities for the creation of intellectual property and to cooperate in patent protection and in exploitation. To secure appropriate external funding and hence staffing and resources for the project, to include preparing grant applications for external funding and developing protocols. To manage existing collaborations, and establish new collaborations, both within the division and the LMB and with external establishments. To have a broad, balanced and informed perspective of current scientific issues especially those pertaining directly to the area of non protein ubiquitylation in the context of infection and cellular homeostasis. To agree the overall strategic direction of your research. You will be expected to take managerial and budgetary responsibility for your research projects, especially the procurement of external funding. Line management responsibilities will be undertaken; these responsibilities, to include staff development and performance management, should be applied in accordance with the MRC's policies and procedures. Training will be given if necessary. Working relationships You will report to Dr Randow and will liaise with other Research Support staff, Postdoctoral Scientists and students, not only in your group, but also across the LMB and with external collaborators. Additional Information The successful applicant must be available to start work no later than 01 July 2026. Person Specification Academic qualifications and experience: PhD in a relevant biological subject. Extensive postdoctoral research experience in non protein ubiq itylation in the context of infection and cellular homeostasis, PROTACs and manipulation of E3 ligase specificity. Technical skills and expertise: Significant experience of and proven expertise in cutting edge research relevant to the project, and knowledge of the field. Particularly useful would be experience in protein purification and the reconstitutions of reactions in vitro. Track record of research: This will include discoveries and significant achievements, and published papers preferably first author. Other relevant evidence of: Independent working and decision making Excellent standards of research conduct Mentoring Originality Influencing skills Communication skills Leadership Intellectual Property Corporate Responsibilities You must at all times carry out your responsibilities with due regard to the UKRI: Code of Conduct Equality, Diversity and Inclusion policy Health and Safety policy Data Protection policy Job descriptions should be reviewed on a regular basis and at the annual appraisal. Any changes should be made and agreed between you and your manager. The above lists are not exhaustive and you are required to undertake such duties as may reasonably be requested within the scope of the post. All employees are required to act professionally, co operatively and flexibly in line with the requirements of the post, the MRC and UKRI. The role holder will be required to have the appropriate level of security screening/vetting required for the role. UKRI reserves the right to run or re run security clearance as required during the course of employment.
UKRI Salary: £46,743. Band: UKRI Band E. Contract: 24 months FTC. Hours: Min 0.7FTE/Full time. Location: Polaris House, Swindon - Hybrid Working Available. Closing Date: Tuesday 16th June 2026 click apply for full job details
May 30, 2026
Seasonal
UKRI Salary: £46,743. Band: UKRI Band E. Contract: 24 months FTC. Hours: Min 0.7FTE/Full time. Location: Polaris House, Swindon - Hybrid Working Available. Closing Date: Tuesday 16th June 2026 click apply for full job details
UKRI is seeking a Chief Financial Officer to provide strategic leadership and advisor to the CEO and Board. This role encompasses oversight of financial management, risk assurance, and stakeholder engagement across a £40 million budget and a portfolio worth £10 billion. The CFO will manage a directorate of around 800 people and ensure robust financial governance aligned with UK government priorities. Strong leadership, stakeholder management, and resilience are essential for success in this pivotal role.
May 29, 2026
Full time
UKRI is seeking a Chief Financial Officer to provide strategic leadership and advisor to the CEO and Board. This role encompasses oversight of financial management, risk assurance, and stakeholder engagement across a £40 million budget and a portfolio worth £10 billion. The CFO will manage a directorate of around 800 people and ensure robust financial governance aligned with UK government priorities. Strong leadership, stakeholder management, and resilience are essential for success in this pivotal role.
Contract Term: This is a permanent, open ended position. Location: London or Swindon. Includes regular travel across the UK and international travel on occasion. Direct Reports: The postholder will have line management responsibility for 7 direct reports, including roles such as Chief Information Officer, Finance Director, and General Counsel & Head of Legal. Availability: Successful candidates will be encouraged to take up appointment ASAP following checks. Security Level: Must hold, or be willing to undergo, Developed Vetting (DV) security clearance. Closing Date: 23:55 on Sunday 7th June 2026. About the Role The Chief Financial Officer (CFO) is a senior strategic leader and principal adviser to the CEO and Board. As a principal decision maker, the CFO provides organisation wide leadership across finance, legal, digital and data, risk and assurance. Alongside the CEO, the CFO is an executive member of the UKRI board. The CFO is responsible for ensuring the organisation manages public money with strong governance, effective stewardship of public funds, and the highest standards of financial management, assurance and control. They provide strategic leadership on all aspects of public sector finance, ensuring financial decisions are evidence based and aligned with government priorities and statutory responsibilities. The CFO leads engagement with Spending Reviews and fiscal planning, ensuring resources are linked to outcomes, forecasts are credible, and management demonstrates strong financial management to stakeholders. Working in partnership with the CEO, the CFO plays a central role in shaping and delivering UKRI's long term strategic vision. The role requires deep understanding of the political, economic and societal context, translating external drivers into strategic priorities and operational plans. The CFO also manages senior leaders, building capability, and engages at the highest levels of government, industry and academia. The CFO will be a member of the Executive Committee and the UKRI Board, leading a directorate of 800 people through 7 direct reports, managing a direct annual budget of £40 million, and overseeing finance and commercials across the UKRI portfolio worth £10 Bn. The CFO will establish a legally robust, risk based governance framework, lead engagement with the Government Internal Audit Agency and Audit Committee, serve as a non executive director on spin out company boards where required, and oversee other professional services within UKRI. Key Responsibilities Provide strategic leadership across UKRI, working closely with the CEO and executive colleagues to shape organisational direction and represent UKRI's interests to internal and external stakeholders. Guide development and execution of UKRI's long term strategy, balancing DSIT objectives, financial constraints and emerging national opportunities. Oversee day to day executive operations as a core member of the Executive Committee, with direct accountability for finance, digital, data, risk and legal across the portfolio. Represent the CEO and UKRI at high level engagements, building trust with industry and stewarding key relationships at central and local government levels. Provide executive leadership over strategic partnerships to enable critical technologies and capabilities that support national priorities and global competitiveness. Serve as a non executive director on UKRI spin out boards where required. Provide robust budget stewardship to ensure UKRI maximises grant utilisation in delivering organisational objectives. Essential Criteria Proven experience leading and developing diverse, high performing teams, set direction, delegate and deliver results through others. Extensive experience holding enterprise wide responsibility for financial probity, governance and effective delivery of financial outcomes within a large, complex organisation. Strong understanding of drivers of UK economic growth, including policy, sectoral and market trends shaping national research and innovation priorities. Exceptional relationship building and stakeholder management skills, establishing credibility quickly and building partnerships with industry, government, universities and external institutions. Highly effective communicator and influencer, operating confidently at Board and senior Government levels, challenging constructively and shaping decision making. Strong personal resilience and sound judgement, making decisions under pressure and maintaining focus on organisational priorities. Demonstrated commitment to personal growth, organisational learning and continuous improvement, contributing to a culture of high performance and innovation.
May 29, 2026
Full time
Contract Term: This is a permanent, open ended position. Location: London or Swindon. Includes regular travel across the UK and international travel on occasion. Direct Reports: The postholder will have line management responsibility for 7 direct reports, including roles such as Chief Information Officer, Finance Director, and General Counsel & Head of Legal. Availability: Successful candidates will be encouraged to take up appointment ASAP following checks. Security Level: Must hold, or be willing to undergo, Developed Vetting (DV) security clearance. Closing Date: 23:55 on Sunday 7th June 2026. About the Role The Chief Financial Officer (CFO) is a senior strategic leader and principal adviser to the CEO and Board. As a principal decision maker, the CFO provides organisation wide leadership across finance, legal, digital and data, risk and assurance. Alongside the CEO, the CFO is an executive member of the UKRI board. The CFO is responsible for ensuring the organisation manages public money with strong governance, effective stewardship of public funds, and the highest standards of financial management, assurance and control. They provide strategic leadership on all aspects of public sector finance, ensuring financial decisions are evidence based and aligned with government priorities and statutory responsibilities. The CFO leads engagement with Spending Reviews and fiscal planning, ensuring resources are linked to outcomes, forecasts are credible, and management demonstrates strong financial management to stakeholders. Working in partnership with the CEO, the CFO plays a central role in shaping and delivering UKRI's long term strategic vision. The role requires deep understanding of the political, economic and societal context, translating external drivers into strategic priorities and operational plans. The CFO also manages senior leaders, building capability, and engages at the highest levels of government, industry and academia. The CFO will be a member of the Executive Committee and the UKRI Board, leading a directorate of 800 people through 7 direct reports, managing a direct annual budget of £40 million, and overseeing finance and commercials across the UKRI portfolio worth £10 Bn. The CFO will establish a legally robust, risk based governance framework, lead engagement with the Government Internal Audit Agency and Audit Committee, serve as a non executive director on spin out company boards where required, and oversee other professional services within UKRI. Key Responsibilities Provide strategic leadership across UKRI, working closely with the CEO and executive colleagues to shape organisational direction and represent UKRI's interests to internal and external stakeholders. Guide development and execution of UKRI's long term strategy, balancing DSIT objectives, financial constraints and emerging national opportunities. Oversee day to day executive operations as a core member of the Executive Committee, with direct accountability for finance, digital, data, risk and legal across the portfolio. Represent the CEO and UKRI at high level engagements, building trust with industry and stewarding key relationships at central and local government levels. Provide executive leadership over strategic partnerships to enable critical technologies and capabilities that support national priorities and global competitiveness. Serve as a non executive director on UKRI spin out boards where required. Provide robust budget stewardship to ensure UKRI maximises grant utilisation in delivering organisational objectives. Essential Criteria Proven experience leading and developing diverse, high performing teams, set direction, delegate and deliver results through others. Extensive experience holding enterprise wide responsibility for financial probity, governance and effective delivery of financial outcomes within a large, complex organisation. Strong understanding of drivers of UK economic growth, including policy, sectoral and market trends shaping national research and innovation priorities. Exceptional relationship building and stakeholder management skills, establishing credibility quickly and building partnerships with industry, government, universities and external institutions. Highly effective communicator and influencer, operating confidently at Board and senior Government levels, challenging constructively and shaping decision making. Strong personal resilience and sound judgement, making decisions under pressure and maintaining focus on organisational priorities. Demonstrated commitment to personal growth, organisational learning and continuous improvement, contributing to a culture of high performance and innovation.
UK Research & Innovation Salary: £58,589 - £74,866 per annum. (Dependent on experience) Band: UKRI Band F. Contract Type: Open ended. Hours: Full-time. (flexible working available) Location: Polaris House, Swindon, Wiltshire or Rutherford Appleton Laboratory, Didcot, Oxon - Hybrid working available click apply for full job details
May 22, 2026
Full time
UK Research & Innovation Salary: £58,589 - £74,866 per annum. (Dependent on experience) Band: UKRI Band F. Contract Type: Open ended. Hours: Full-time. (flexible working available) Location: Polaris House, Swindon, Wiltshire or Rutherford Appleton Laboratory, Didcot, Oxon - Hybrid working available click apply for full job details
UK Research & Innovation Salary: £58,589 - £74,866 per annum. (Dependent on experience) Band: UKRI Band F. Contract Type: Open ended. Hours: Full-time. (flexible working available) Location: Polaris House, Swindon, Wiltshire or Rutherford Appleton Laboratory, Didcot, Oxon - Hybrid working available click apply for full job details
May 19, 2026
Full time
UK Research & Innovation Salary: £58,589 - £74,866 per annum. (Dependent on experience) Band: UKRI Band F. Contract Type: Open ended. Hours: Full-time. (flexible working available) Location: Polaris House, Swindon, Wiltshire or Rutherford Appleton Laboratory, Didcot, Oxon - Hybrid working available click apply for full job details
A leading research organization in Harwell UK is seeking a motivated placement student to join their Technology Department. The student will engage in valuable projects, particularly in X-ray camera development. Responsibilities include conducting experiments, data analysis, and communication of results. Ideal candidates should have a solid academic background in Physics or Electronics and practical skills in electronics or data processing. Benefits include 30 days of holiday, flexible working, and excellent learning opportunities.
Mar 06, 2026
Full time
A leading research organization in Harwell UK is seeking a motivated placement student to join their Technology Department. The student will engage in valuable projects, particularly in X-ray camera development. Responsibilities include conducting experiments, data analysis, and communication of results. Ideal candidates should have a solid academic background in Physics or Electronics and practical skills in electronics or data processing. Benefits include 30 days of holiday, flexible working, and excellent learning opportunities.
