Angle Plc

ANGLE is a world-leading liquid biopsy company commercialising a patent protected platform technology that can capture rare circulating tumour cells (CTCs) from blood, in a minimally invasive way, for downstream analysis. ANGLE's Parsortix system is FDA cleared for its intended use in metastatic breast cancer and is currently the first and only FDA cleared medical device to harvest intact circulating cancer cells from blood. Parsortix technology comprises a microfluidic device that captures CTCs from blood based on their size and compressibility. CTCs are cancer cells that have detached from the primary tumour and entered the blood circulation, and they play a critical role in initiating metastasis. Once harvested, the CTCs can be comprehensively analysed to provide a wealth of information about the patient's tumour, advancing cancer research and potentially personalized medicine. This technology has the potential to deliver profound improvements in clinical and health economic outcomes. ANGLE has established a CTC harvest and analysis service from our UK-based Clinical Laboratory based in Guildford for customers worldwide. In alignment with company priorities, we plan to rapidly expand our services to include molecular profiling of CTCs and ctDNA using digital PCR and NGS to add to our image-based assays. Join our Team This is an exciting time at ANGLE and our team in Guildford are looking for a Director of Operations. The Director of Operations is responsible for the company's daily operations, ensuring efficiency, compliance with industry standards (specifically ISO 13485), and alignment with the company's strategic goals to drive effectiveness, scalability and growth. This role oversees manufacturing, supply chain, logistics, supplier management, and procurement activities ensuring that systems, processes, and people are aligned to deliver operational excellence. A key focus of this role is building and leading high-performing teams to support sustainable growth and continuous improvement while maintaining compliance with relevant standards and regulations At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading-edge translational research into clinical diagnostics. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas. We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume. Principal Accountabilities The Director of Operations is responsible for the company's daily operations, ensuring efficiency, compliance with industry standards (specifically ISO 13485), and alignment with the company's strategic goals to drive effectiveness, scalability and growth. This role oversees manufacturing, supply chain, logistics, supplier management, and procurement activities ensuring that systems, processes, and people are aligned to deliver operational excellence. A key focus of this role is building and leading high-performing teams to support sustainable growth and continuous improvement while maintaining compliance with relevant standards and regulations. Lead and manage daily operations, ensuring smooth execution across all functions while optimizing resources, systems, and processes for maximum efficiency and effectiveness. Design and implement operational strategies aligned with business objectives to drive scalable and sustainable growth. Lead and manage the Sales and Operations Planning (S&OP) process to ensure alignment between demand, supply, and business goals. Ensure the process is well-coordinated, efficient, and supports overall business performance. Responsible for contract management, lead the review, drafting, and negotiation of contracts with suppliers and external manufacturers, ensuring favourable terms and mitigating risks. Process Optimization, continuously assess and improve operational processes, implementing innovations to enhance efficiency, quality, and cost-effectiveness. Develop and manage all operational budgets, ensuring resources are allocated effectively and operational costs are controlled within financial constraints. Responsible for ensuring smooth and efficient technical transfer from R&D to Manufacturing, enabling successful scale-up and production readiness. Risk Management and Compliance, identify and mitigate operational risks, ensuring compliance with regulatory requirements and company policies. Define and track key performance indicators (KPIs) to monitor operational performance, identify areas of improvement and inform strategic decision-making. Collaborate with other departments to ensure alignment and seamless execution of company objectives. Build and mentor high-performing teams, fostering a culture of accountability and continuous improvement. Provide training, mentorship, and performance evaluations to enhance team performance. Any other ad hoc responsibilities as required Qualifications, Experience, Knowledge and Attributes Bachelor's degree in business administration, Operations Management, Supply Chain, or a related field. An MBA or relevant advanced degree is preferred. 10+ years of progressive experience in senior operations leadership roles, particularly in supply chain, manufacturing, or operations management, with a focus on the medical device or regulated industries. Strong knowledge of ISO 13485 regulations and quality management systems including documentation, risk management, and audit processes. Extensive knowledge of operational best practices and process improvement methodologies Expertise in contract management, supplier negotiations, and supplier relationship management. Exceptional leadership and interpersonal skills with the ability to motivate, build and manage teams effectively Analytical mindset with excellent problem-solving and decision-making abilities to implement effective solutions. Excellent communication and interpersonal skills to collaborate effectively with senior leadership, staff, and external stakeholders. Experience in budget management and cost optimization. An eye for detail and commitment to high quality data A flexible, adaptable approach to meeting the diverse demands of the role. Job Requirements Due to the nature of the role, our requirement is for this position to be Guildford based 5 days per week. As a member of our highly skilled team you will receive opportunities for training and development and a competitive benefits package. Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs. Furthermore, please be advised that if you submit an application to us for this position, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates. Important notice to Employment Businesses/Agencies ANGLE does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact our ANGLE recruitment team to obtain prior written authorisation before referring any candidates. In the absence of such written authorisation being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of ANGLE. ANGLE shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Discover how ANGLE can help with your liquid biopsy needs