The Rosalind Franklin Institute

Research Assistant 3 Year Fixed Term Contract We are seeking a highly motivated Research Assistant to support cutting-edge research in cell-cell interaction in epithelia. The role will focus on the development and genetic modification of human gut organoid and cell models, including the generation of fluorescently tagged proteins and disease-relevant phenotypes. The role will involve apply molecular biology techniques including DNA cloning, qPCR, and sequencing, CRISPR/Cas9 genome editing, advanced 2D and 3D cell culture, and fluorescence imaging techniques including super resolution. The post-holder will handle human tissue samples in compliance with HTA regulations and prepare growth factors for organoid maintenance. The successful candidate will support a collaborative, multidisciplinary research environment. Key Responsibilities Research Assistant As a Research Assistant at the Franklin, you will become an integral part of the research team, supporting the work of scientists, by ensuring the smooth running of the labs. You will manage technologies and reagents and provide services to support the work of students and scientists of all levels. You may also be asked to undertake well defined experimental protocols in a supervised fashion. You will also: Work with students and teams of researchers/technologists around established projects. Manage day to day running of the facilities and ensure that specific activities within the lab perform well. Keep meticulous records, ensuring compliance of lab processes, ordering and stocking, maintenance and operations. Support use of facilities, production of samples or performing aspects on behalf of researchers, with due consideration to health and safety. Be supervised by Lab Managers/Scientists. Be involved in scientific portfolio, including publications, projects or conferences. In return we offer: 25 days holidays plus bank holidays and Christmas holiday shutdown Generous pension scheme (employer s contribution currently up to 18%) Group Life Assurance (also known as Group Life Insurance or Death in Service) Hub building with state-of-the-art laboratories Hybrid and flexible working Training and development opportunities for staff at all levels Bus pass discount scheme and good transport links to Oxford and surrounding areas Cycle to Work Scheme Access to employee discount platform (Perkbox) Occupational Health and wellbeing support including Employee Assistance (24/7 support and counselling) Health Cash Plan Subsidised canteen and food outlets on campus Free on-site parking Campus location in beautiful countryside with social and sports clubs open to staff

Health, Safety, Environment & Compliance (HSEC) Coordinator The role of the HSEC Coordinator involves a variety of responsibilities aimed to ensure compliance with Health and Safety and environmental regulations. With a primary focus around Health and Safety, this role supports the H&S Advisor and also works closely with the Facilities Team, Quality, Human Resources and Laboratory Managers. As a Health, Safety, Environment and Compliance (HSEC) Coordinator you will: Health and Safety Work with the H&S Advisor and Laboratory Managers to ensure staff are familiar with health and safety risks, controls and emergency procedures. Support audits and inspections, incident reporting and preparing reports and monitoring resolution of any issues arising by collaborating with Laboratory Managers and staff. Assist in preparing Health and Safety documentation (Safety Codes, COSHH, Risk Assessments etc.) and promoting health, safety and compliance within the Institute. Carry out site H&S Inductions, including site risks, for new employees, contractors and visitors, and monitor/manage contractor access. Assist with maintaining fire procedures, including drills and regular check on all equipment in conjunction with Building Fire Manager. Support the Health and Safety work plan. Actively participate in H&S Committee meetings. Full job details can be found HERE