Organisation/Company John Innes Centre Research Field Biological sciences " Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country United Kingdom Application Deadline 2 Aug 2025 - 23:59 (Europe/London) Type of Contract Temporary Job Status Full-time Hours Per Week 37 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology. About the John Innes Centre: The John Innes Centre is an independent, international centre of excellence in plant and microbial sciences. We nurture a creative, curiosity-led approach to answering fundamental questions in bioscience, and translate that knowledge into societal benefits. Our strategic vision, Healthy Plants, Healthy People, Healthy Planet , sets out our ambitious long-term goals for the game changing impact of our science globally. Our employees enjoy access to state-of-the-art technology and a diverse range of specialist training opportunities, including support for leadership and management. Click here to find out more about working at the John Innes Centre. About the Howard Group: The Howard group combines simple, predictive mathematical and biophysical modelling with long-lasting experimental collaborations to dissect biological mechanisms too complex to unravel by experiments alone. In many cases we are able to rationalise complex biological dynamics into simple underlying mechanisms, with few components and interactions. Our approach is highly interdisciplinary and relies heavily on the techniques of statistical physics and applied mathematics, as well as on close collaboration with experimental groups. At present there are two main research areas in the group: probing how epigenetic memory states are set up and then stably maintained, and understanding patterning dynamics in sub-cellular biological systems. For epigenetics, we work on both histone modification memory systems, particularly the Polycomb silencing system, as well as on DNA methylation. For patterning, the main application at present is to the dynamics of crossover positioning in meiosis. The group regularly publishes in the most prominent multidisciplinary journals, with recent papers in Nature, Science, Cell Systems, eLife, Molecular Cell and PNAS. Several previous members of the Howard group now hold independent faculty positions of their own, including in Warwick, Glasgow, Sydney, Amsterdam and Munich. The role: The main purpose of the position is to develop predictive computational models of epigenetic dynamics, collaborating particularly with the experimental group of Prof Rob Klose in the Dept of Biochemistry, Oxford University. The models will enhance our understanding of how the Polycomb system silences gene expression and how such a silenced memory state can be stably maintained through many cell cycles. Theposition is funded by Wellcome and would suit an individual with a high degree of independence and vision, able to advance the project independently. The successful candidate will have a rare opportunity to work on fundamental biological processes in a truly interdisciplinary environment, with seamless collaboration with a leading experimental group. The ideal candidate: The ideal candidate will possess (or soon complete) a PhD in Theoretical Physics, Bio-Mathematics or Computational Biology. They will possess a strong interest in biological problems and have achieved demonstrable scientific success in previous roles. Prior experience of biological modelling is desirable but not essential. Additional information: This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Where the successful applicant requires a visa, we will fund the costs for their visa and the Immigration Health Surcharge. Please contact the Human Resources Team if you have any questions regarding your application or visa options. We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. We are proud to hold a prestigious Gold Athena SWAN award in recognition of our inclusive culture, commitment and good practices towards advancing of gender equality. We offer an exciting, stimulating, diverse research environment and actively promote a family friendly workplace. The Institute is also a member of Stonewall's Diversity Champions programme. The John Innes Centre is a registered charity (No. 223852) grant-aided by the Biotechnology and Biological Sciences Research Council.
Jul 03, 2025
Full time
Organisation/Company John Innes Centre Research Field Biological sciences " Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country United Kingdom Application Deadline 2 Aug 2025 - 23:59 (Europe/London) Type of Contract Temporary Job Status Full-time Hours Per Week 37 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology. About the John Innes Centre: The John Innes Centre is an independent, international centre of excellence in plant and microbial sciences. We nurture a creative, curiosity-led approach to answering fundamental questions in bioscience, and translate that knowledge into societal benefits. Our strategic vision, Healthy Plants, Healthy People, Healthy Planet , sets out our ambitious long-term goals for the game changing impact of our science globally. Our employees enjoy access to state-of-the-art technology and a diverse range of specialist training opportunities, including support for leadership and management. Click here to find out more about working at the John Innes Centre. About the Howard Group: The Howard group combines simple, predictive mathematical and biophysical modelling with long-lasting experimental collaborations to dissect biological mechanisms too complex to unravel by experiments alone. In many cases we are able to rationalise complex biological dynamics into simple underlying mechanisms, with few components and interactions. Our approach is highly interdisciplinary and relies heavily on the techniques of statistical physics and applied mathematics, as well as on close collaboration with experimental groups. At present there are two main research areas in the group: probing how epigenetic memory states are set up and then stably maintained, and understanding patterning dynamics in sub-cellular biological systems. For epigenetics, we work on both histone modification memory systems, particularly the Polycomb silencing system, as well as on DNA methylation. For patterning, the main application at present is to the dynamics of crossover positioning in meiosis. The group regularly publishes in the most prominent multidisciplinary journals, with recent papers in Nature, Science, Cell Systems, eLife, Molecular Cell and PNAS. Several previous members of the Howard group now hold independent faculty positions of their own, including in Warwick, Glasgow, Sydney, Amsterdam and Munich. The role: The main purpose of the position is to develop predictive computational models of epigenetic dynamics, collaborating particularly with the experimental group of Prof Rob Klose in the Dept of Biochemistry, Oxford University. The models will enhance our understanding of how the Polycomb system silences gene expression and how such a silenced memory state can be stably maintained through many cell cycles. Theposition is funded by Wellcome and would suit an individual with a high degree of independence and vision, able to advance the project independently. The successful candidate will have a rare opportunity to work on fundamental biological processes in a truly interdisciplinary environment, with seamless collaboration with a leading experimental group. The ideal candidate: The ideal candidate will possess (or soon complete) a PhD in Theoretical Physics, Bio-Mathematics or Computational Biology. They will possess a strong interest in biological problems and have achieved demonstrable scientific success in previous roles. Prior experience of biological modelling is desirable but not essential. Additional information: This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Where the successful applicant requires a visa, we will fund the costs for their visa and the Immigration Health Surcharge. Please contact the Human Resources Team if you have any questions regarding your application or visa options. We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. We are proud to hold a prestigious Gold Athena SWAN award in recognition of our inclusive culture, commitment and good practices towards advancing of gender equality. We offer an exciting, stimulating, diverse research environment and actively promote a family friendly workplace. The Institute is also a member of Stonewall's Diversity Champions programme. The John Innes Centre is a registered charity (No. 223852) grant-aided by the Biotechnology and Biological Sciences Research Council.
Organisation/Company: UNIVERSITY OF SOUTHAMPTON Research Field: Engineering Researcher Profile: Recognised Researcher (R2), First Stage Researcher (R1) Country: United Kingdom Application Deadline: 9 Jul 2025 - 00:00 (UTC) Type of Contract: Permanent Job Status: Full-time Funding: Not funded by a EU programme Research Infrastructure: No Offer Description Join a world-renowned University and explore your ambitions in engineering research and education. The University of Southampton invites applications for lecturer or associate professor positions within the Mechanical Engineering Department in the Faculty of Engineering and Physical Sciences. Successful candidates will contribute to our culture of research, education, and enterprise, inspiring students and fostering discovery. About the role We are looking for enthusiastic individuals to join the Mechanical Engineering department, integrating into existing research groups or contributing to the Southampton Advanced Manufacturing and Design Hub (SAMDH). Your expertise should align with strategic growth areas such as: Future mobility, automotive wear, dynamics, propulsion, and fuels. Thermofluidic and cryogenic systems for energy applications. Advanced manufacturing, AI-assisted design, and production. Mechatronics, bio-engineering, control systems, robotics, and e-skins. Candidate requirements Ambitious plans for an independent research program. Potential to secure external research funding. Ability to inspire students and colleagues. Commitment to diversity and inclusion. What we offer A collaborative, research-led environment. Access to high-performance facilities. Relocation support, pension scheme, holiday allowance, health facilities, and discounts. The University values diversity and encourages applications from under-represented groups, supporting flexible working arrangements and career breaks. Located an hour from London, Southampton offers a vibrant city life and beautiful surroundings. Learn more about the University and city here . Application process Interviews are scheduled for 21st/22nd August 2025. For advice on your suitability or research areas, contact Professor Richard Wills at . To apply, click the "Apply Online" link and submit your CV and a cover letter detailing your research plans and vision.
Jun 23, 2025
Full time
Organisation/Company: UNIVERSITY OF SOUTHAMPTON Research Field: Engineering Researcher Profile: Recognised Researcher (R2), First Stage Researcher (R1) Country: United Kingdom Application Deadline: 9 Jul 2025 - 00:00 (UTC) Type of Contract: Permanent Job Status: Full-time Funding: Not funded by a EU programme Research Infrastructure: No Offer Description Join a world-renowned University and explore your ambitions in engineering research and education. The University of Southampton invites applications for lecturer or associate professor positions within the Mechanical Engineering Department in the Faculty of Engineering and Physical Sciences. Successful candidates will contribute to our culture of research, education, and enterprise, inspiring students and fostering discovery. About the role We are looking for enthusiastic individuals to join the Mechanical Engineering department, integrating into existing research groups or contributing to the Southampton Advanced Manufacturing and Design Hub (SAMDH). Your expertise should align with strategic growth areas such as: Future mobility, automotive wear, dynamics, propulsion, and fuels. Thermofluidic and cryogenic systems for energy applications. Advanced manufacturing, AI-assisted design, and production. Mechatronics, bio-engineering, control systems, robotics, and e-skins. Candidate requirements Ambitious plans for an independent research program. Potential to secure external research funding. Ability to inspire students and colleagues. Commitment to diversity and inclusion. What we offer A collaborative, research-led environment. Access to high-performance facilities. Relocation support, pension scheme, holiday allowance, health facilities, and discounts. The University values diversity and encourages applications from under-represented groups, supporting flexible working arrangements and career breaks. Located an hour from London, Southampton offers a vibrant city life and beautiful surroundings. Learn more about the University and city here . Application process Interviews are scheduled for 21st/22nd August 2025. For advice on your suitability or research areas, contact Professor Richard Wills at . To apply, click the "Apply Online" link and submit your CV and a cover letter detailing your research plans and vision.
Organisation/Company QIB - Quadram Institute Bioscience Research Field Biological sciences Biological sciences " Biology Technology " Biotechnology Computer science Environmental science Environmental science Biological sciences Mathematics " Statistics Researcher Profile Leading Researcher (R4) Established Researcher (R3) Country United Kingdom Application Deadline 8 Jul 2025 - 21:59 (UTC) Type of Contract Permanent Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Research Scientist (Soil Metagenomics) QIB - Quadram Institute Bioscience Norwich, United Kingdom Applications are invited for a Research Scientist to join the Laboratory of Dr Hildebrand at Quadram Institute, Norwich, UK. Background: This post is part of the NERC project "Identifying novel microbial drivers to mitigate atmospheric methane emission". Methane is a powerful greenhouse gas, and we aim to reveal the role of ammonia oxidizing Archaea in methane oxidation in the environment. The project will determine how methane affects soil microbial communities, and how specific soil microorganisms respond to methane and metabolise it. The postholder will work with sequencing data derived from cultivated and natural soil microbiomes, to understand the role of prokaryotes (Archaea and Bacteria) in mitigating greenhouse gas emissions. The role: The project holder will use metagenomics (similar to doi:10.1038/s-6, 10 15314, 10.1186/s5-1) to profile both taxonomic and functional compositions of for SIP-enriched metagenomic and metatranscriptomic sequencing and functional-targeted amplicon sequencing data, interpreting experiments conducted in the laboratory of Prof Laura Lehtovirta-Morley. The bioinformatic tools will be developed to analyse and correct these data types, the statistical workflows established to interpret and understand how microorganisms respond to methane in both pristine and laboratory-based soil communities, building on tools available in the Hildebrand group . Long-term, this work will advance our understanding of biogeochemical cycling, contribute to reducing the impact of climate change by manipulating existing microbial communities, and understanding how healthy soil microbiomes are established, and maintained. The environment: The Hildebrand group uses metagenomics to research the diversity, community interactions, and evolution of microbes in communities using custom software solutions. The Lehtovirta-Morley group explores environmental microbiomes and biogeochemical cycling using both cultivation-independent and cultivation-dependent experiments. Both groups collaborate closely on microbial archaeal research in soils. The research is situated at the Norwich Research Park (NRP) UK, that encompasses the University of East Anglia, 4 BBSRC Institute, > 15 companies, 3,000 researchers and clinicians, 17,000 students. Norwich ranked in the top 10 for UK cities with a beautiful, historical town centre and an active gastropub & coffee aficionado scene. The applicant is expected to help in the supervision of junior group members and to represent the group at trainings. The applicant will have direct access to established PacBio/ONT, Hi-C and single cell sequencing facilities, as well as one of UK's largest HPC cluster at the NRP. The ideal candidate: The applicant needs to hold a PhD (or equivalent) in biology, bioinformatics, computer science or a related discipline with a background and/or interest in at least one of the following subjects: Microbiomes & biodiversity; Ecology & evolution. The ideal candidate will have a keen interest in soil microbiology and biogeochemical cycling, and experience in conducting scientific experiments independently, writing papers, presenting work and grant writing. Basic statistics and programming skills (either R, python, Perl, C++, or equivalent) is expected. Specialized skills will be taught and developed through mentorship and collaborations. Additional information: Salary on appointment will be within the range £36,720 to £42,000 per annum depending on qualifications and experience. This is a full-time post for a contract of 9 months, potentially extensible for a further 9 months. For further information and details of how to apply, please visit our website or contact the Human Resources team on or quoting reference . This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options. Interviews will likely be held around 14 July 2025. We are committed to equity, diversity and inclusion, and welcome applications from all sectors of society. The Institute values of Respect, Innovation, Collaboration and Excellence are at the heart of all we do, and we expect all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. About the Quadram Institute: The Quadram Institute is a new interdisciplinary research institute dedicated to understanding how food and microbes interact to promote health and prevent disease. Its mission is to deliver healthier lives through innovation in gut health, microbiology and food. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a state-of-the-art building on the Norwich Research Park. This is one of Europe's largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. ( ). T he closing date for applications will be 8 July 2025 . The Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer.
Jun 10, 2025
Full time
Organisation/Company QIB - Quadram Institute Bioscience Research Field Biological sciences Biological sciences " Biology Technology " Biotechnology Computer science Environmental science Environmental science Biological sciences Mathematics " Statistics Researcher Profile Leading Researcher (R4) Established Researcher (R3) Country United Kingdom Application Deadline 8 Jul 2025 - 21:59 (UTC) Type of Contract Permanent Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Research Scientist (Soil Metagenomics) QIB - Quadram Institute Bioscience Norwich, United Kingdom Applications are invited for a Research Scientist to join the Laboratory of Dr Hildebrand at Quadram Institute, Norwich, UK. Background: This post is part of the NERC project "Identifying novel microbial drivers to mitigate atmospheric methane emission". Methane is a powerful greenhouse gas, and we aim to reveal the role of ammonia oxidizing Archaea in methane oxidation in the environment. The project will determine how methane affects soil microbial communities, and how specific soil microorganisms respond to methane and metabolise it. The postholder will work with sequencing data derived from cultivated and natural soil microbiomes, to understand the role of prokaryotes (Archaea and Bacteria) in mitigating greenhouse gas emissions. The role: The project holder will use metagenomics (similar to doi:10.1038/s-6, 10 15314, 10.1186/s5-1) to profile both taxonomic and functional compositions of for SIP-enriched metagenomic and metatranscriptomic sequencing and functional-targeted amplicon sequencing data, interpreting experiments conducted in the laboratory of Prof Laura Lehtovirta-Morley. The bioinformatic tools will be developed to analyse and correct these data types, the statistical workflows established to interpret and understand how microorganisms respond to methane in both pristine and laboratory-based soil communities, building on tools available in the Hildebrand group . Long-term, this work will advance our understanding of biogeochemical cycling, contribute to reducing the impact of climate change by manipulating existing microbial communities, and understanding how healthy soil microbiomes are established, and maintained. The environment: The Hildebrand group uses metagenomics to research the diversity, community interactions, and evolution of microbes in communities using custom software solutions. The Lehtovirta-Morley group explores environmental microbiomes and biogeochemical cycling using both cultivation-independent and cultivation-dependent experiments. Both groups collaborate closely on microbial archaeal research in soils. The research is situated at the Norwich Research Park (NRP) UK, that encompasses the University of East Anglia, 4 BBSRC Institute, > 15 companies, 3,000 researchers and clinicians, 17,000 students. Norwich ranked in the top 10 for UK cities with a beautiful, historical town centre and an active gastropub & coffee aficionado scene. The applicant is expected to help in the supervision of junior group members and to represent the group at trainings. The applicant will have direct access to established PacBio/ONT, Hi-C and single cell sequencing facilities, as well as one of UK's largest HPC cluster at the NRP. The ideal candidate: The applicant needs to hold a PhD (or equivalent) in biology, bioinformatics, computer science or a related discipline with a background and/or interest in at least one of the following subjects: Microbiomes & biodiversity; Ecology & evolution. The ideal candidate will have a keen interest in soil microbiology and biogeochemical cycling, and experience in conducting scientific experiments independently, writing papers, presenting work and grant writing. Basic statistics and programming skills (either R, python, Perl, C++, or equivalent) is expected. Specialized skills will be taught and developed through mentorship and collaborations. Additional information: Salary on appointment will be within the range £36,720 to £42,000 per annum depending on qualifications and experience. This is a full-time post for a contract of 9 months, potentially extensible for a further 9 months. For further information and details of how to apply, please visit our website or contact the Human Resources team on or quoting reference . This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options. Interviews will likely be held around 14 July 2025. We are committed to equity, diversity and inclusion, and welcome applications from all sectors of society. The Institute values of Respect, Innovation, Collaboration and Excellence are at the heart of all we do, and we expect all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. About the Quadram Institute: The Quadram Institute is a new interdisciplinary research institute dedicated to understanding how food and microbes interact to promote health and prevent disease. Its mission is to deliver healthier lives through innovation in gut health, microbiology and food. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a state-of-the-art building on the Norwich Research Park. This is one of Europe's largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. ( ). T he closing date for applications will be 8 July 2025 . The Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer.