CK Group are recruiting for a Market Research and Insights Partner, to join a global pharmaceutical company, based in Slough, on a contract basis, initially for 3 months. This role can be fully remote. Salary: Inside IR35. £34.75 per hour (PAYE) or £47.31 per hour (Umbrella). Flexible for experienced candidates. Market Research and Insights Partner: This position will lead primarily within the immunology portfolio, but there may be the opportunity to work with other therapy areas, according to need. Planning and leading agreed market research (across PVUs and stakeholders, with a planned primary allocation); ensuring that HCP, patient, and payer insights are at the heart of brand strategies / tactics, e.g., campaigns. Ensuring all Market Research complies with the Pharmaco-Vigilance Safety Reporting obligations and ensures contracts contain the right PV clauses, vendors receive the right PV training and execute correctly on their PV obligations. Taking joint leadership on the management of the agreed market research activities, spear-heading new and emerging research methodologies if appropriate. Working closely together with the regional analytics teams in either US and/or Europe to ensure the right use of existing data sources support to answer business questions in the most effective way. Your Background : Successful track record in previous market research roles within pharma industry (agency or client side) for at least 7 years. Strong understanding of relevant commercial and medical data, and primary market research methods and applications. Ability to advise on stakeholder insights needs through a deep understanding of the business and knowledge of relevant available insights. Strong quantitative, qualitative and interpretation skills, and you are a structured problem solver. Company: Our client is a global biopharmaceutical company, focused on creating value for people living with severe diseases in immunology and neurology now and into the future. Location: Hybrid in Slough or fully remote. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDKA
Jun 18, 2025
Full time
CK Group are recruiting for a Market Research and Insights Partner, to join a global pharmaceutical company, based in Slough, on a contract basis, initially for 3 months. This role can be fully remote. Salary: Inside IR35. £34.75 per hour (PAYE) or £47.31 per hour (Umbrella). Flexible for experienced candidates. Market Research and Insights Partner: This position will lead primarily within the immunology portfolio, but there may be the opportunity to work with other therapy areas, according to need. Planning and leading agreed market research (across PVUs and stakeholders, with a planned primary allocation); ensuring that HCP, patient, and payer insights are at the heart of brand strategies / tactics, e.g., campaigns. Ensuring all Market Research complies with the Pharmaco-Vigilance Safety Reporting obligations and ensures contracts contain the right PV clauses, vendors receive the right PV training and execute correctly on their PV obligations. Taking joint leadership on the management of the agreed market research activities, spear-heading new and emerging research methodologies if appropriate. Working closely together with the regional analytics teams in either US and/or Europe to ensure the right use of existing data sources support to answer business questions in the most effective way. Your Background : Successful track record in previous market research roles within pharma industry (agency or client side) for at least 7 years. Strong understanding of relevant commercial and medical data, and primary market research methods and applications. Ability to advise on stakeholder insights needs through a deep understanding of the business and knowledge of relevant available insights. Strong quantitative, qualitative and interpretation skills, and you are a structured problem solver. Company: Our client is a global biopharmaceutical company, focused on creating value for people living with severe diseases in immunology and neurology now and into the future. Location: Hybrid in Slough or fully remote. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDKA
Microwave Heating and Current Drive Physicist (2-Year FTA) Abingdon Rd, Culham, UK Full-time Salary: £42,858 (inclusive of Specialist Allowance) + excellent benefits including outstanding pension Division: Plasma Science and Fusion Operations Site Location: UKAEA Culham, Oxfordshire Confirmed Grade: Level 4 Department: Tokamak Systems Company Description By 2050, the planet could be using twice as much electricity compared to today. Are you interested in contributing and helping to shape the future of the world's energy? If so, read on. Fusion, the process that powers the Sun and Stars, is one of the most promising options for generating the cleaner, carbon-free energy that our world badly needs. UKAEA leads the way in realising fusion energy, partnering with industry and research for ground-breaking advancements. Our goal is to bring fusion electricity to the grid, supported by tomorrow's power stations. In pursuit of our mission, UKAEA embraces core values: Innovative, Committed, Trusted, and Collaborative. As an employee of UKAEA, you will benefit from: Outstanding defined benefit pension scheme, details of which can be found at the end of this advert. Corporate bonus scheme up to 7% and a Relocation allowance (if eligible). Flexible working options including family friendly policies and the right to request flexible working from the start of your employment. Employee Assistance Programme and trained Mental Health First Aiders. Generous annual leave allowance starting with 25 days, plus 3 days' Christmas closure and 2.5 privilege days, in addition to UK bank holidays. Wide range of career development opportunities. A vibrant culture committed to equality and being fully inclusive. Job Description The salary for this role is £42,858. Onsite working is expected for 3 days each week, however, we actively support requests for flexible working. This role is based in Culham, Oxfordshire. This role requires employees to complete an online Baseline Personnel Security Standard (BPSS), including The Disclosure & Barring Service (DBS) checks for criminal convictions and possibly a search of open source data. The Role Are you looking for an exciting opportunity to make a difference? Join our team and contribute to the future of fusion energy. As Microwave Heating and Current Drive Physicist, you will play a pivotal role in developing theoretical models of microwave plasma interaction and designing and implementing experiments to test theoretical predictions. Key Accountabilities: Develop theoretical models for microwave-plasma interaction, with a particular focus on Electron Bernstein Wave interaction. Design, plan and execute experiments to test theoretical predictions. Develop diagnostics specific to microwave-plasma interaction. Publish research in peer reviewed journals. Publicise work internally, and at national and international conferences. Participate actively in collaborations with external partners. Qualifications Essential: PhD in plasma physics. Strong track record in publishing research in the area of microwave-plasma interaction. Experience with Electron Bernstein Waves is desired. Experience presenting material at international conferences. Excellent communications skills, both oral and written, and ability to interact with various stakeholders (wider physics team, MAST-U management, external collaborators etc.). Your career development as a scientist will be strongly supported, including working towards chartership with the Institute of Physics. Additional Information For a full list of benefits and to apply, select the apply button to be taken through to the UKAEA careers pages. We welcome talented people from all backgrounds who want to help us achieve our mission. We encourage applications from under-represented groups, particularly from women in STEM, people from Black British Caribbean and African, Pakistani and Bangladeshi British, and other ethnic minority backgrounds, people with disabilities, and neurotypical individuals. Our Executive team, supported by our 'Head of Equality, Diversity and Inclusion' (EDI) and Wellbeing and our EDI Networks actively promote Inclusion and takes steps to increase diversity within our organisation. We reinforce best practices in recruitment and selection and evaluate approaches to remove barriers to success. Please note that vacancies are generally advertised for 4 weeks but may close earlier if we receive a large number of applications. For applicants applying from outside the United Kingdom or those who have spent time outside the UK in the last five years, please visit the UK Government website for information on criminal records checks. If your country of residence or previous residence is not listed on the website or if the UK Government does not have information on obtaining a criminal records check from that state, we regret to inform you that we cannot process your application.
Jun 18, 2025
Full time
Microwave Heating and Current Drive Physicist (2-Year FTA) Abingdon Rd, Culham, UK Full-time Salary: £42,858 (inclusive of Specialist Allowance) + excellent benefits including outstanding pension Division: Plasma Science and Fusion Operations Site Location: UKAEA Culham, Oxfordshire Confirmed Grade: Level 4 Department: Tokamak Systems Company Description By 2050, the planet could be using twice as much electricity compared to today. Are you interested in contributing and helping to shape the future of the world's energy? If so, read on. Fusion, the process that powers the Sun and Stars, is one of the most promising options for generating the cleaner, carbon-free energy that our world badly needs. UKAEA leads the way in realising fusion energy, partnering with industry and research for ground-breaking advancements. Our goal is to bring fusion electricity to the grid, supported by tomorrow's power stations. In pursuit of our mission, UKAEA embraces core values: Innovative, Committed, Trusted, and Collaborative. As an employee of UKAEA, you will benefit from: Outstanding defined benefit pension scheme, details of which can be found at the end of this advert. Corporate bonus scheme up to 7% and a Relocation allowance (if eligible). Flexible working options including family friendly policies and the right to request flexible working from the start of your employment. Employee Assistance Programme and trained Mental Health First Aiders. Generous annual leave allowance starting with 25 days, plus 3 days' Christmas closure and 2.5 privilege days, in addition to UK bank holidays. Wide range of career development opportunities. A vibrant culture committed to equality and being fully inclusive. Job Description The salary for this role is £42,858. Onsite working is expected for 3 days each week, however, we actively support requests for flexible working. This role is based in Culham, Oxfordshire. This role requires employees to complete an online Baseline Personnel Security Standard (BPSS), including The Disclosure & Barring Service (DBS) checks for criminal convictions and possibly a search of open source data. The Role Are you looking for an exciting opportunity to make a difference? Join our team and contribute to the future of fusion energy. As Microwave Heating and Current Drive Physicist, you will play a pivotal role in developing theoretical models of microwave plasma interaction and designing and implementing experiments to test theoretical predictions. Key Accountabilities: Develop theoretical models for microwave-plasma interaction, with a particular focus on Electron Bernstein Wave interaction. Design, plan and execute experiments to test theoretical predictions. Develop diagnostics specific to microwave-plasma interaction. Publish research in peer reviewed journals. Publicise work internally, and at national and international conferences. Participate actively in collaborations with external partners. Qualifications Essential: PhD in plasma physics. Strong track record in publishing research in the area of microwave-plasma interaction. Experience with Electron Bernstein Waves is desired. Experience presenting material at international conferences. Excellent communications skills, both oral and written, and ability to interact with various stakeholders (wider physics team, MAST-U management, external collaborators etc.). Your career development as a scientist will be strongly supported, including working towards chartership with the Institute of Physics. Additional Information For a full list of benefits and to apply, select the apply button to be taken through to the UKAEA careers pages. We welcome talented people from all backgrounds who want to help us achieve our mission. We encourage applications from under-represented groups, particularly from women in STEM, people from Black British Caribbean and African, Pakistani and Bangladeshi British, and other ethnic minority backgrounds, people with disabilities, and neurotypical individuals. Our Executive team, supported by our 'Head of Equality, Diversity and Inclusion' (EDI) and Wellbeing and our EDI Networks actively promote Inclusion and takes steps to increase diversity within our organisation. We reinforce best practices in recruitment and selection and evaluate approaches to remove barriers to success. Please note that vacancies are generally advertised for 4 weeks but may close earlier if we receive a large number of applications. For applicants applying from outside the United Kingdom or those who have spent time outside the UK in the last five years, please visit the UK Government website for information on criminal records checks. If your country of residence or previous residence is not listed on the website or if the UK Government does not have information on obtaining a criminal records check from that state, we regret to inform you that we cannot process your application.
Criticality Safety Assessor - Nuclear Physics Location: RG7 4PR , located between Reading and Basingstoke, with free onsite parking . Due to the classified nature of the work involved, there are limited opportunities to work from home in this role. It is anticipated that the successful candidate will spend the majority of their time working on site at AWE Aldermaston. Packages: Junior Criticality Safety Assessor (university graduate or relevant nuclear safety/operations experience) £33,000 - £37,000 plus role related allowance(s) (depending on your suitability, qualifications, and level of experience) Experienced Criticality Safety Assessor (PhD graduate or university graduates with some relevant experience or significant relevant nuclear safety/operations experience) £39,500 - £47,500 plus role related allowance(s) (depending on your suitability, qualifications, and level of experience) Working pattern: AWE operates a 9-day working fortnight. We will consider flexible working requests so that your work may fit in with your lifestyle. Just let us know your preferred working pattern on your application. Let us introduce the role Join AWE in the UK's largest Criticality Safety Group to support safe nuclear operations in defence of the nation and develop your nuclear career! We are currently looking to expand our Criticality Safety Group and are seeking committed, talented people who want to work in the field of nuclear criticality science and safety. We welcome applications to join our dynamic team as Criticality Safety Assessors from people with diverse skillsets and backgrounds and who are at any stage of their career. Our goal is to grow our internationally recognised, highly capable, friendly, and supportive group to meet the increasing demands of a challenging programme of work in support of the UK's nuclear deterrent. As AWE's Criticality Safety Group , our role is to provide an in-house criticality safety assessment capability in support of delivering the company's strategic objectives. This involves the delivery of criticality safety assessments during the design, operation, and decommissioning phases of nuclear facilities, which form a part of our nuclear safety documentation that satisfies our Nuclear Site Licence Conditions. The Criticality Safety Assessor role is multidisciplinary and involves the combination of a strong technical understanding of the nuclear physics of criticality with a working knowledge of writing safety assessments, as well as familiarity of, and interaction with, many other professional disciplines. A Criticality Safety Assessor applies nuclear physics knowledge and uses nuclear data to solve complex problems; uses Monte Carlo computer codes; and undertakes Hazard Identification and fault analysis to find out how a criticality could occur. Typical Criticality Safety Assessor Responsibilities: Deliver criticality safety assessments to facilities in line with the programme demand and our internal company procedures; Maintain and promote high personal standards in environment, safety, health, security and quality as well as professional conduct in-line with our core behaviours; Engage and collaborate with stakeholders from technology centres, operations, project management, engineers, and conventional safety case teams; Directly support work with nuclear material through criticality safety assessment support in a nuclear baseline role which is a key nuclear safety requirement. Training and development is provided to learn the skills required to become a competent Criticality Safety Assessor. This involves a mixture of training exercises and on-the-job training as well as visits to nuclear facilities on site. There are also many additional opportunities for staff to diversify their work including: Delivering criticality safety training courses to workers on site; Undertaking facility inspections to appraise operational performance against criticality safety good practice; Regular knowledge transfer activities and continuous professional development opportunities; Opportunities to specialise in support for specific technology centres. Who Are We Looking For? We will need you to have: Honours Degree (or equivalent) in science, mathematics, engineering or a closely related discipline or an equivalent level of work experience. Examples of being able to communicate technical problems, clearly and concisely, to stakeholders with technical/non-technical backgrounds. Desirable experience/skills (development in these areas provided through training for successful candidates): An understanding of relevant technical topics which include: nuclear physics, physics of criticality, mathematics, statistics, chemistry and metallurgy of fissile material; Experience of demonstrating good engineering and scientific judgement with experience in using fundamental engineering and scientific skills; Knowledge of particle transport codes - Monte Carlo and deterministic methods e.g. MONK and/or MCNP; An understanding of the requirements placed upon fissile operations within a highly regulated industry on a nuclear licensed site; An understanding of the nuclear regulatory framework within the UK and/or an overview of the different regulatory methods outside the UK; Familiarity with assessment and analysis methodologies used in the field of criticality safety. Some reasons we think you'll love it here: AWE has wide range of benefits to suit you. These include: 9-day working fortnight - meaning you get every other Friday off work, in addition to 270 hours of annual leave. Market leading contributory pension scheme (we will pay between 9% and 13% of your pensionable pay depending on your contributions). Family friendly policies: Maternity Leave - 39 Weeks Full Pay and Paternity Leave - 4 Weeks Full Pay. Opportunities for Professional Career Development including funding for annual membership of a relevant professional body. Employee Assistance Programme and Occupational Health Services. Life Assurance (4 x annual salary). Discounts - access to savings on a wide range of everyday spending. Special Leave Policy including paid time off for volunteering, public service (including reserve forces) and caring. The 'Working at AWE' page on our website is where you can find full details in the 'AWE Benefits Guide'.
Jun 18, 2025
Full time
Criticality Safety Assessor - Nuclear Physics Location: RG7 4PR , located between Reading and Basingstoke, with free onsite parking . Due to the classified nature of the work involved, there are limited opportunities to work from home in this role. It is anticipated that the successful candidate will spend the majority of their time working on site at AWE Aldermaston. Packages: Junior Criticality Safety Assessor (university graduate or relevant nuclear safety/operations experience) £33,000 - £37,000 plus role related allowance(s) (depending on your suitability, qualifications, and level of experience) Experienced Criticality Safety Assessor (PhD graduate or university graduates with some relevant experience or significant relevant nuclear safety/operations experience) £39,500 - £47,500 plus role related allowance(s) (depending on your suitability, qualifications, and level of experience) Working pattern: AWE operates a 9-day working fortnight. We will consider flexible working requests so that your work may fit in with your lifestyle. Just let us know your preferred working pattern on your application. Let us introduce the role Join AWE in the UK's largest Criticality Safety Group to support safe nuclear operations in defence of the nation and develop your nuclear career! We are currently looking to expand our Criticality Safety Group and are seeking committed, talented people who want to work in the field of nuclear criticality science and safety. We welcome applications to join our dynamic team as Criticality Safety Assessors from people with diverse skillsets and backgrounds and who are at any stage of their career. Our goal is to grow our internationally recognised, highly capable, friendly, and supportive group to meet the increasing demands of a challenging programme of work in support of the UK's nuclear deterrent. As AWE's Criticality Safety Group , our role is to provide an in-house criticality safety assessment capability in support of delivering the company's strategic objectives. This involves the delivery of criticality safety assessments during the design, operation, and decommissioning phases of nuclear facilities, which form a part of our nuclear safety documentation that satisfies our Nuclear Site Licence Conditions. The Criticality Safety Assessor role is multidisciplinary and involves the combination of a strong technical understanding of the nuclear physics of criticality with a working knowledge of writing safety assessments, as well as familiarity of, and interaction with, many other professional disciplines. A Criticality Safety Assessor applies nuclear physics knowledge and uses nuclear data to solve complex problems; uses Monte Carlo computer codes; and undertakes Hazard Identification and fault analysis to find out how a criticality could occur. Typical Criticality Safety Assessor Responsibilities: Deliver criticality safety assessments to facilities in line with the programme demand and our internal company procedures; Maintain and promote high personal standards in environment, safety, health, security and quality as well as professional conduct in-line with our core behaviours; Engage and collaborate with stakeholders from technology centres, operations, project management, engineers, and conventional safety case teams; Directly support work with nuclear material through criticality safety assessment support in a nuclear baseline role which is a key nuclear safety requirement. Training and development is provided to learn the skills required to become a competent Criticality Safety Assessor. This involves a mixture of training exercises and on-the-job training as well as visits to nuclear facilities on site. There are also many additional opportunities for staff to diversify their work including: Delivering criticality safety training courses to workers on site; Undertaking facility inspections to appraise operational performance against criticality safety good practice; Regular knowledge transfer activities and continuous professional development opportunities; Opportunities to specialise in support for specific technology centres. Who Are We Looking For? We will need you to have: Honours Degree (or equivalent) in science, mathematics, engineering or a closely related discipline or an equivalent level of work experience. Examples of being able to communicate technical problems, clearly and concisely, to stakeholders with technical/non-technical backgrounds. Desirable experience/skills (development in these areas provided through training for successful candidates): An understanding of relevant technical topics which include: nuclear physics, physics of criticality, mathematics, statistics, chemistry and metallurgy of fissile material; Experience of demonstrating good engineering and scientific judgement with experience in using fundamental engineering and scientific skills; Knowledge of particle transport codes - Monte Carlo and deterministic methods e.g. MONK and/or MCNP; An understanding of the requirements placed upon fissile operations within a highly regulated industry on a nuclear licensed site; An understanding of the nuclear regulatory framework within the UK and/or an overview of the different regulatory methods outside the UK; Familiarity with assessment and analysis methodologies used in the field of criticality safety. Some reasons we think you'll love it here: AWE has wide range of benefits to suit you. These include: 9-day working fortnight - meaning you get every other Friday off work, in addition to 270 hours of annual leave. Market leading contributory pension scheme (we will pay between 9% and 13% of your pensionable pay depending on your contributions). Family friendly policies: Maternity Leave - 39 Weeks Full Pay and Paternity Leave - 4 Weeks Full Pay. Opportunities for Professional Career Development including funding for annual membership of a relevant professional body. Employee Assistance Programme and Occupational Health Services. Life Assurance (4 x annual salary). Discounts - access to savings on a wide range of everyday spending. Special Leave Policy including paid time off for volunteering, public service (including reserve forces) and caring. The 'Working at AWE' page on our website is where you can find full details in the 'AWE Benefits Guide'.
CK Group are working in partnership with Nxera Pharma to recruit a Senior or Lead Scientist, Immunology, Translational Medicine, to join their Translational Biology Immunology and Metabolism group. The ideal candidate will have immunology expertise in inflammatory or autoimmune disease, and expertise in planning and executing preclinical target validation, and translational studies to support project deliverables. Location: Granta Park, Cambridge. About the company: Nxera Pharma (formerly Sosei Heptares) is a technology powered biopharma company, in pursuit of new speciality medicines to improve the lives of patients with unmet needs globally. Their pipeline is focused on addressing major unmet needs in some of the fastest-growing areas of medicine across CNS, GI and immunology, metabolic disorders and rare diseases, and leverages the power of their unique and industry leading GPCR-targeted structure-based drug discovery NxWave platform to provide a sustainable source of best- or first-in-class candidates. In Cambridge UK, Nxera have built outstanding capabilities across their platform, discovery and translational medicine teams, to advance multiple programs from pre-clinical through to early clinical development. About the role: This is an exciting opportunity to work across diverse functional groups within Nxera Pharma and with external industrial and academic collaborators. The Translational Biology Team is a multidisciplinary team focused on understanding the mechanisms underlying human disease biology. The ideal candidate will be passionate about advancing novel therapies, and biomarker strategies for the treatment of immune disorders. Responsibilities will include: Leading, executing and driving new Target Identification and Validation initiatives. Ensuring a robust translational framework is embedded early in the project lifetime to drive clear decision making in the clinic. Oversee the development and optimisation of functional immunology assays and/or in vivo PD studies at CROs. Depending on experience, may act as the Project Translational lead. Skills and Experience: PhD with 2-3 years drug discovery or development experience or BSc with at least 5 years drug discovery or development experience in inflammatory or autoimmune therapeutic areas. Extensive experience in the planning, analysis, and interpretation of in vitro and in vivo target validation and translational studies. Proven technical knowledge in interrogating complex immunological mechanisms using a range of in vitro and ex vivo immunological assays (e.g. isolated leukocyte subset functional assays, flow cytometry, RNA expression analysis, biochemical signalling, MSD/ELISA, imaging). Strong track record in human and rodent primary immune cell assay development and optimisation. Direct experience in the experimental design and oversight of in vivo studies and good understanding of Home Office legislation governing in vivo research. Proven ability to work effectively in a fast paced, multidisciplinary matrix team environment. Excellent interpersonal, communication and presentation skills and ability to thrive in team setting. Desirable: Hands-on experience in managing outsourced studies with CROs or academic partners. Project leadership experience within a biotech or pharma setting, alternatively if coming from an academic background experience working in industry collaborations would be beneficial. Interest in metabolic disease or experience working in this area What s in it for you? State-of-the-art R&D centre located in the heart of the Cambridge science cluster. Competitive compensation package including discretionary cash bonuses. Eligible for grants of Restricted Stock Units. 26 days annual leave in addition to public holidays plus the option to purchase an additional 5 days each year. Employer contribution to pension. Private Medical Insurance for employees and family and a cash plan for dental and optical reimbursement. Health and wellbeing benefits including a subsidised individual gym membership. Income protection to cover long term absences due to ill health. Group Death in Service equal to 4x basic annual salary. Apply: Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDLS
Jun 18, 2025
Full time
CK Group are working in partnership with Nxera Pharma to recruit a Senior or Lead Scientist, Immunology, Translational Medicine, to join their Translational Biology Immunology and Metabolism group. The ideal candidate will have immunology expertise in inflammatory or autoimmune disease, and expertise in planning and executing preclinical target validation, and translational studies to support project deliverables. Location: Granta Park, Cambridge. About the company: Nxera Pharma (formerly Sosei Heptares) is a technology powered biopharma company, in pursuit of new speciality medicines to improve the lives of patients with unmet needs globally. Their pipeline is focused on addressing major unmet needs in some of the fastest-growing areas of medicine across CNS, GI and immunology, metabolic disorders and rare diseases, and leverages the power of their unique and industry leading GPCR-targeted structure-based drug discovery NxWave platform to provide a sustainable source of best- or first-in-class candidates. In Cambridge UK, Nxera have built outstanding capabilities across their platform, discovery and translational medicine teams, to advance multiple programs from pre-clinical through to early clinical development. About the role: This is an exciting opportunity to work across diverse functional groups within Nxera Pharma and with external industrial and academic collaborators. The Translational Biology Team is a multidisciplinary team focused on understanding the mechanisms underlying human disease biology. The ideal candidate will be passionate about advancing novel therapies, and biomarker strategies for the treatment of immune disorders. Responsibilities will include: Leading, executing and driving new Target Identification and Validation initiatives. Ensuring a robust translational framework is embedded early in the project lifetime to drive clear decision making in the clinic. Oversee the development and optimisation of functional immunology assays and/or in vivo PD studies at CROs. Depending on experience, may act as the Project Translational lead. Skills and Experience: PhD with 2-3 years drug discovery or development experience or BSc with at least 5 years drug discovery or development experience in inflammatory or autoimmune therapeutic areas. Extensive experience in the planning, analysis, and interpretation of in vitro and in vivo target validation and translational studies. Proven technical knowledge in interrogating complex immunological mechanisms using a range of in vitro and ex vivo immunological assays (e.g. isolated leukocyte subset functional assays, flow cytometry, RNA expression analysis, biochemical signalling, MSD/ELISA, imaging). Strong track record in human and rodent primary immune cell assay development and optimisation. Direct experience in the experimental design and oversight of in vivo studies and good understanding of Home Office legislation governing in vivo research. Proven ability to work effectively in a fast paced, multidisciplinary matrix team environment. Excellent interpersonal, communication and presentation skills and ability to thrive in team setting. Desirable: Hands-on experience in managing outsourced studies with CROs or academic partners. Project leadership experience within a biotech or pharma setting, alternatively if coming from an academic background experience working in industry collaborations would be beneficial. Interest in metabolic disease or experience working in this area What s in it for you? State-of-the-art R&D centre located in the heart of the Cambridge science cluster. Competitive compensation package including discretionary cash bonuses. Eligible for grants of Restricted Stock Units. 26 days annual leave in addition to public holidays plus the option to purchase an additional 5 days each year. Employer contribution to pension. Private Medical Insurance for employees and family and a cash plan for dental and optical reimbursement. Health and wellbeing benefits including a subsidised individual gym membership. Income protection to cover long term absences due to ill health. Group Death in Service equal to 4x basic annual salary. Apply: Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDLS
Job Title: Senior Laboratory Research Scientist - Specialist Virology Researcher (SLRS) Details of the role : Full-time, permanent. Working pattern: Monday - Friday. Salary : From £45,7000 pa with benefits, subject to skills and experience Application closing date : 23/06/:59 GMT About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role Over the first year of the COVID-19 pandemic, the Crick developed a range of COVID-19 research platforms, including a unique high throughput live virus assay platform to quantify neutralising antibody activity against a range of SARS-CoV-2 variants in thousands of samples simultaneously. In collaboration with both clinical researchers and the Worldwide Influenza Centre (WIC) based at the Crick, we have used our microneutralisation platform to show at large scale how immunity to COVID-19 following vaccination and infection differs between healthy adults and clinically vulnerable patients. The Crick's COVID Surveillance Unit (CSU) was created in 2021 to run and improve upon this high-throughput live-virus assay pipeline. We are seeking to appoint a talented, collaborative, and self-motivated scientist to fill a full-time on-site laboratory position within the COVID Surveillance Unit (CSU) team. The team is responsible for the day to day running of a microneutralisation assay pipeline and you will either be capable of, or be willing to learn, all aspects of the pipeline to contribute to a dynamic and fluid team. You will need to horizon scan in the development of future assay platforms by interacting with Crick and external researchers and maintaining up to date knowledge of high-throughput technologies, virological and immunological techniques and advances. This is an opportunity to use your scientific and technical skills in a clinically vital enterprise and shape its development with your knowledge and expertise within one of the largest research institutes in Europe. What you will be doing As an SLRS at the Crick, you will: Ensuring the smooth operation of the neutralisation assay pipeline by conducting assays to the highest standards, liaising with all interested parties and team members ensuring clear communication. Managing workflows and ensuring neutralisation data is generated in a timely manner agreed with end users. The team must be adaptable and flexible in order to quickly adjust ongoing scheduled work to accommodate the unexpected. Providing experimental or technical support/assistance to other team members, and provide expertise feedback/input for the development, refinement, and troubleshooting of existing and novel methodologies. Isolation, propagation and genetic/molecular characterisation of newly emerging and reference SARS-CoV-2 and seasonal influenza viruses Managing and generating stocks of pseudoviruses and RG viruses for the neutralisation assay pipeline Applying understanding of the assay pipeline to adapting and/or developing new high throughput virological and immunological assays. Undertaking own research project, designing, and executing experiments /with strategic direction from the group head. About you The essential criteria you will bring PhD or equivalent qualification/experience in virology, immunology, or high throughput methodologies Extensive direct experience in cell-based assays, tissue culture, and immunofluorescence-staining techniques Previous experience in working with respiratory viruses, pseudoviruses, and RG viruses Previous experience in working with immunoassays Practical experience with a wide range of molecular and cell biology techniques Experience with data analysis and visualisation using R and/or Python To see the complete job description, click here . To learn more about team click here . About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold . We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open . We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial . We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and you will be asked as part of the process if you wish to apply under the scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas : Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme : Defined contribution pension with employer contributions of up to 16%. Health & Well-being : 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks : Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition : Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 18, 2025
Full time
Job Title: Senior Laboratory Research Scientist - Specialist Virology Researcher (SLRS) Details of the role : Full-time, permanent. Working pattern: Monday - Friday. Salary : From £45,7000 pa with benefits, subject to skills and experience Application closing date : 23/06/:59 GMT About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role Over the first year of the COVID-19 pandemic, the Crick developed a range of COVID-19 research platforms, including a unique high throughput live virus assay platform to quantify neutralising antibody activity against a range of SARS-CoV-2 variants in thousands of samples simultaneously. In collaboration with both clinical researchers and the Worldwide Influenza Centre (WIC) based at the Crick, we have used our microneutralisation platform to show at large scale how immunity to COVID-19 following vaccination and infection differs between healthy adults and clinically vulnerable patients. The Crick's COVID Surveillance Unit (CSU) was created in 2021 to run and improve upon this high-throughput live-virus assay pipeline. We are seeking to appoint a talented, collaborative, and self-motivated scientist to fill a full-time on-site laboratory position within the COVID Surveillance Unit (CSU) team. The team is responsible for the day to day running of a microneutralisation assay pipeline and you will either be capable of, or be willing to learn, all aspects of the pipeline to contribute to a dynamic and fluid team. You will need to horizon scan in the development of future assay platforms by interacting with Crick and external researchers and maintaining up to date knowledge of high-throughput technologies, virological and immunological techniques and advances. This is an opportunity to use your scientific and technical skills in a clinically vital enterprise and shape its development with your knowledge and expertise within one of the largest research institutes in Europe. What you will be doing As an SLRS at the Crick, you will: Ensuring the smooth operation of the neutralisation assay pipeline by conducting assays to the highest standards, liaising with all interested parties and team members ensuring clear communication. Managing workflows and ensuring neutralisation data is generated in a timely manner agreed with end users. The team must be adaptable and flexible in order to quickly adjust ongoing scheduled work to accommodate the unexpected. Providing experimental or technical support/assistance to other team members, and provide expertise feedback/input for the development, refinement, and troubleshooting of existing and novel methodologies. Isolation, propagation and genetic/molecular characterisation of newly emerging and reference SARS-CoV-2 and seasonal influenza viruses Managing and generating stocks of pseudoviruses and RG viruses for the neutralisation assay pipeline Applying understanding of the assay pipeline to adapting and/or developing new high throughput virological and immunological assays. Undertaking own research project, designing, and executing experiments /with strategic direction from the group head. About you The essential criteria you will bring PhD or equivalent qualification/experience in virology, immunology, or high throughput methodologies Extensive direct experience in cell-based assays, tissue culture, and immunofluorescence-staining techniques Previous experience in working with respiratory viruses, pseudoviruses, and RG viruses Previous experience in working with immunoassays Practical experience with a wide range of molecular and cell biology techniques Experience with data analysis and visualisation using R and/or Python To see the complete job description, click here . To learn more about team click here . About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold . We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open . We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial . We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and you will be asked as part of the process if you wish to apply under the scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas : Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme : Defined contribution pension with employer contributions of up to 16%. Health & Well-being : 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks : Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition : Comprehensive training, mentoring, and a pay structure based on skills and experience.
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 18, 2025
Full time
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Job Title: Senior Laboratory Research Scientist - Specialist Virology Researcher (SLRS) Details of the role : Full-time, permanent. Working pattern: Monday - Friday. Salary : From £45,7000 pa with benefits, subject to skills and experience Application closing date : 23/06/:59 GMT About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role Over the first year of the COVID-19 pandemic, the Crick developed a range of COVID-19 research platforms, including a unique high throughput live virus assay platform to quantify neutralising antibody activity against a range of SARS-CoV-2 variants in thousands of samples simultaneously. In collaboration with both clinical researchers and the Worldwide Influenza Centre (WIC) based at the Crick, we have used our microneutralisation platform to show at large scale how immunity to COVID-19 following vaccination and infection differs between healthy adults and clinically vulnerable patients. The Crick's COVID Surveillance Unit (CSU) was created in 2021 to run and improve upon this high-throughput live-virus assay pipeline. We are seeking to appoint a talented, collaborative, and self-motivated scientist to fill a full-time on-site laboratory position within the COVID Surveillance Unit (CSU) team. The team is responsible for the day to day running of a microneutralisation assay pipeline and you will either be capable of, or be willing to learn, all aspects of the pipeline to contribute to a dynamic and fluid team. You will need to horizon scan in the development of future assay platforms by interacting with Crick and external researchers and maintaining up to date knowledge of high-throughput technologies, virological and immunological techniques and advances. This is an opportunity to use your scientific and technical skills in a clinically vital enterprise and shape its development with your knowledge and expertise within one of the largest research institutes in Europe. What you will be doing As an SLRS at the Crick, you will: Ensuring the smooth operation of the neutralisation assay pipeline by conducting assays to the highest standards, liaising with all interested parties and team members ensuring clear communication. Managing workflows and ensuring neutralisation data is generated in a timely manner agreed with end users. The team must be adaptable and flexible in order to quickly adjust ongoing scheduled work to accommodate the unexpected. Providing experimental or technical support/assistance to other team members, and provide expertise feedback/input for the development, refinement, and troubleshooting of existing and novel methodologies. Isolation, propagation and genetic/molecular characterisation of newly emerging and reference SARS-CoV-2 and seasonal influenza viruses Managing and generating stocks of pseudoviruses and RG viruses for the neutralisation assay pipeline Applying understanding of the assay pipeline to adapting and/or developing new high throughput virological and immunological assays. Undertaking own research project, designing, and executing experiments /with strategic direction from the group head. About you The essential criteria you will bring PhD or equivalent qualification/experience in virology, immunology, or high throughput methodologies Extensive direct experience in cell-based assays, tissue culture, and immunofluorescence-staining techniques Previous experience in working with respiratory viruses, pseudoviruses, and RG viruses Previous experience in working with immunoassays Practical experience with a wide range of molecular and cell biology techniques Experience with data analysis and visualisation using R and/or Python To see the complete job description, click here . To learn more about team click here . About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold . We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open . We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial . We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and you will be asked as part of the process if you wish to apply under the scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas : Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme : Defined contribution pension with employer contributions of up to 16%. Health & Well-being : 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks : Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition : Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 18, 2025
Full time
Job Title: Senior Laboratory Research Scientist - Specialist Virology Researcher (SLRS) Details of the role : Full-time, permanent. Working pattern: Monday - Friday. Salary : From £45,7000 pa with benefits, subject to skills and experience Application closing date : 23/06/:59 GMT About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role Over the first year of the COVID-19 pandemic, the Crick developed a range of COVID-19 research platforms, including a unique high throughput live virus assay platform to quantify neutralising antibody activity against a range of SARS-CoV-2 variants in thousands of samples simultaneously. In collaboration with both clinical researchers and the Worldwide Influenza Centre (WIC) based at the Crick, we have used our microneutralisation platform to show at large scale how immunity to COVID-19 following vaccination and infection differs between healthy adults and clinically vulnerable patients. The Crick's COVID Surveillance Unit (CSU) was created in 2021 to run and improve upon this high-throughput live-virus assay pipeline. We are seeking to appoint a talented, collaborative, and self-motivated scientist to fill a full-time on-site laboratory position within the COVID Surveillance Unit (CSU) team. The team is responsible for the day to day running of a microneutralisation assay pipeline and you will either be capable of, or be willing to learn, all aspects of the pipeline to contribute to a dynamic and fluid team. You will need to horizon scan in the development of future assay platforms by interacting with Crick and external researchers and maintaining up to date knowledge of high-throughput technologies, virological and immunological techniques and advances. This is an opportunity to use your scientific and technical skills in a clinically vital enterprise and shape its development with your knowledge and expertise within one of the largest research institutes in Europe. What you will be doing As an SLRS at the Crick, you will: Ensuring the smooth operation of the neutralisation assay pipeline by conducting assays to the highest standards, liaising with all interested parties and team members ensuring clear communication. Managing workflows and ensuring neutralisation data is generated in a timely manner agreed with end users. The team must be adaptable and flexible in order to quickly adjust ongoing scheduled work to accommodate the unexpected. Providing experimental or technical support/assistance to other team members, and provide expertise feedback/input for the development, refinement, and troubleshooting of existing and novel methodologies. Isolation, propagation and genetic/molecular characterisation of newly emerging and reference SARS-CoV-2 and seasonal influenza viruses Managing and generating stocks of pseudoviruses and RG viruses for the neutralisation assay pipeline Applying understanding of the assay pipeline to adapting and/or developing new high throughput virological and immunological assays. Undertaking own research project, designing, and executing experiments /with strategic direction from the group head. About you The essential criteria you will bring PhD or equivalent qualification/experience in virology, immunology, or high throughput methodologies Extensive direct experience in cell-based assays, tissue culture, and immunofluorescence-staining techniques Previous experience in working with respiratory viruses, pseudoviruses, and RG viruses Previous experience in working with immunoassays Practical experience with a wide range of molecular and cell biology techniques Experience with data analysis and visualisation using R and/or Python To see the complete job description, click here . To learn more about team click here . About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold . We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open . We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial . We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and you will be asked as part of the process if you wish to apply under the scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas : Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme : Defined contribution pension with employer contributions of up to 16%. Health & Well-being : 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks : Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition : Comprehensive training, mentoring, and a pay structure based on skills and experience.
CK Group are recruiting for a Customer Account Manager, to join a company in the pharmaceutical industry, on a contract basis for 12 months, working field based in the Sheffield area. Salary: Per day: £237 - £281.93 PAYE or £314 - £373 UMB. Customer Account Manager Role: Build deep meaningful long term commercial relationships within your assigned customer base. Provide excellent customer experience by co-creating service delivery plans & managing timely interventions of all the cross functional teams to provide a positive customer experience. Oversee the customer experience through the entire life cycle in close collaboration with stakeholders in the cross functional team including sales, marketing, technical services, customer services, finance and others as appropriate. Your Background : Educated to degree level or equivalent. Demonstrate a sound track record in contract management and commercial engagement within the healthcare industry. A strategic thinker who holds the customer at the heart of what you do on a daily basis. Great communication, account management, project management and problem-solving skills. Company: Our client is one of the world's premier innovative biopharmaceutical companies, discovering, developing and providing over 160 different medicines, vaccines and consumer healthcare products to help improve the lives of millions of people in the UK and around the world every year. Location: This role is field based within the Sheffield area but will involve occasional travel to site in Burgess Hill. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news.
Jun 18, 2025
Full time
CK Group are recruiting for a Customer Account Manager, to join a company in the pharmaceutical industry, on a contract basis for 12 months, working field based in the Sheffield area. Salary: Per day: £237 - £281.93 PAYE or £314 - £373 UMB. Customer Account Manager Role: Build deep meaningful long term commercial relationships within your assigned customer base. Provide excellent customer experience by co-creating service delivery plans & managing timely interventions of all the cross functional teams to provide a positive customer experience. Oversee the customer experience through the entire life cycle in close collaboration with stakeholders in the cross functional team including sales, marketing, technical services, customer services, finance and others as appropriate. Your Background : Educated to degree level or equivalent. Demonstrate a sound track record in contract management and commercial engagement within the healthcare industry. A strategic thinker who holds the customer at the heart of what you do on a daily basis. Great communication, account management, project management and problem-solving skills. Company: Our client is one of the world's premier innovative biopharmaceutical companies, discovering, developing and providing over 160 different medicines, vaccines and consumer healthcare products to help improve the lives of millions of people in the UK and around the world every year. Location: This role is field based within the Sheffield area but will involve occasional travel to site in Burgess Hill. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news.
CK Group are working in partnership with Nxera Pharma to recruit a Senior or Lead Scientist, Immunology, Translational Medicine, to join their Translational Biology Immunology and Metabolism group. The ideal candidate will have immunology expertise in inflammatory or autoimmune disease, and expertise in planning and executing preclinical target validation, and translational studies to support project deliverables. Location: Granta Park, Cambridge. About the company: Nxera Pharma (formerly Sosei Heptares) is a technology powered biopharma company, in pursuit of new speciality medicines to improve the lives of patients with unmet needs globally. Their pipeline is focused on addressing major unmet needs in some of the fastest-growing areas of medicine across CNS, GI and immunology, metabolic disorders and rare diseases, and leverages the power of their unique and industry leading GPCR-targeted structure-based drug discovery NxWave platform to provide a sustainable source of best- or first-in-class candidates. In Cambridge UK, Nxera have built outstanding capabilities across their platform, discovery and translational medicine teams, to advance multiple programs from pre-clinical through to early clinical development. About the role: This is an exciting opportunity to work across diverse functional groups within Nxera Pharma and with external industrial and academic collaborators. The Translational Biology Team is a multidisciplinary team focused on understanding the mechanisms underlying human disease biology. The ideal candidate will be passionate about advancing novel therapies, and biomarker strategies for the treatment of immune disorders. Responsibilities will include: Leading, executing and driving new Target Identification and Validation initiatives. Ensuring a robust translational framework is embedded early in the project lifetime to drive clear decision making in the clinic. Oversee the development and optimisation of functional immunology assays and/or in vivo PD studies at CROs. Depending on experience, may act as the Project Translational lead. Skills and Experience: PhD with 2-3 years drug discovery or development experience or BSc with at least 5 years drug discovery or development experience in inflammatory or autoimmune therapeutic areas. Extensive experience in the planning, analysis, and interpretation of in vitro and in vivo target validation and translational studies. Proven technical knowledge in interrogating complex immunological mechanisms using a range of in vitro and ex vivo immunological assays (e.g. isolated leukocyte subset functional assays, flow cytometry, RNA expression analysis, biochemical signalling, MSD/ELISA, imaging). Strong track record in human and rodent primary immune cell assay development and optimisation. Direct experience in the experimental design and oversight of in vivo studies and good understanding of Home Office legislation governing in vivo research. Proven ability to work effectively in a fast paced, multidisciplinary matrix team environment. Excellent interpersonal, communication and presentation skills and ability to thrive in team setting. Desirable: Hands-on experience in managing outsourced studies with CROs or academic partners. Project leadership experience within a biotech or pharma setting, alternatively if coming from an academic background experience working in industry collaborations would be beneficial. Interest in metabolic disease or experience working in this area What s in it for you? State-of-the-art R&D centre located in the heart of the Cambridge science cluster. Competitive compensation package including discretionary cash bonuses. Eligible for grants of Restricted Stock Units. 26 days annual leave in addition to public holidays plus the option to purchase an additional 5 days each year. Employer contribution to pension. Private Medical Insurance for employees and family and a cash plan for dental and optical reimbursement. Health and wellbeing benefits including a subsidised individual gym membership. Income protection to cover long term absences due to ill health. Group Death in Service equal to 4x basic annual salary. Apply: Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDLS
Jun 18, 2025
Full time
CK Group are working in partnership with Nxera Pharma to recruit a Senior or Lead Scientist, Immunology, Translational Medicine, to join their Translational Biology Immunology and Metabolism group. The ideal candidate will have immunology expertise in inflammatory or autoimmune disease, and expertise in planning and executing preclinical target validation, and translational studies to support project deliverables. Location: Granta Park, Cambridge. About the company: Nxera Pharma (formerly Sosei Heptares) is a technology powered biopharma company, in pursuit of new speciality medicines to improve the lives of patients with unmet needs globally. Their pipeline is focused on addressing major unmet needs in some of the fastest-growing areas of medicine across CNS, GI and immunology, metabolic disorders and rare diseases, and leverages the power of their unique and industry leading GPCR-targeted structure-based drug discovery NxWave platform to provide a sustainable source of best- or first-in-class candidates. In Cambridge UK, Nxera have built outstanding capabilities across their platform, discovery and translational medicine teams, to advance multiple programs from pre-clinical through to early clinical development. About the role: This is an exciting opportunity to work across diverse functional groups within Nxera Pharma and with external industrial and academic collaborators. The Translational Biology Team is a multidisciplinary team focused on understanding the mechanisms underlying human disease biology. The ideal candidate will be passionate about advancing novel therapies, and biomarker strategies for the treatment of immune disorders. Responsibilities will include: Leading, executing and driving new Target Identification and Validation initiatives. Ensuring a robust translational framework is embedded early in the project lifetime to drive clear decision making in the clinic. Oversee the development and optimisation of functional immunology assays and/or in vivo PD studies at CROs. Depending on experience, may act as the Project Translational lead. Skills and Experience: PhD with 2-3 years drug discovery or development experience or BSc with at least 5 years drug discovery or development experience in inflammatory or autoimmune therapeutic areas. Extensive experience in the planning, analysis, and interpretation of in vitro and in vivo target validation and translational studies. Proven technical knowledge in interrogating complex immunological mechanisms using a range of in vitro and ex vivo immunological assays (e.g. isolated leukocyte subset functional assays, flow cytometry, RNA expression analysis, biochemical signalling, MSD/ELISA, imaging). Strong track record in human and rodent primary immune cell assay development and optimisation. Direct experience in the experimental design and oversight of in vivo studies and good understanding of Home Office legislation governing in vivo research. Proven ability to work effectively in a fast paced, multidisciplinary matrix team environment. Excellent interpersonal, communication and presentation skills and ability to thrive in team setting. Desirable: Hands-on experience in managing outsourced studies with CROs or academic partners. Project leadership experience within a biotech or pharma setting, alternatively if coming from an academic background experience working in industry collaborations would be beneficial. Interest in metabolic disease or experience working in this area What s in it for you? State-of-the-art R&D centre located in the heart of the Cambridge science cluster. Competitive compensation package including discretionary cash bonuses. Eligible for grants of Restricted Stock Units. 26 days annual leave in addition to public holidays plus the option to purchase an additional 5 days each year. Employer contribution to pension. Private Medical Insurance for employees and family and a cash plan for dental and optical reimbursement. Health and wellbeing benefits including a subsidised individual gym membership. Income protection to cover long term absences due to ill health. Group Death in Service equal to 4x basic annual salary. Apply: Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDLS
CK Group are currently recruiting for a Laboratory Technician, to join a materials and polymers manufacturing company, at their site based in Ware. Your normal working day will be from 8am to 5pm Mon-Fri. The Company: Our client develops and manufactures high performance polymers, for use in various applications. Location: This role is located near Hertford, easily commutable from North London, Hoddesdon, Harlow, Stevenage and surrounding areas. The Role: Your main duties will be: Production quality control. Non-hazardous and hazardous chemical handling. Laboratory equipment maintenance and any other machinery/equipment relevant to RnD activities. Maintain frequently used solutions and apparatus. Assist with design and development and testing of new products. Conduct experiments and ensure compliance with safety protocols. Accurately collect experimental data and ensure records are properly maintained. Your Background: The ideal candidate for this role will have the following skills and experience: Degree qualified in Chemistry or equivalent. Organised & methodical with excellent administration and document control skills. Highly motivated, with a 'can do' attitude. Ability to work under pressure and/or to strict deadlines. Able to drive to get to site. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDCH
Jun 18, 2025
Full time
CK Group are currently recruiting for a Laboratory Technician, to join a materials and polymers manufacturing company, at their site based in Ware. Your normal working day will be from 8am to 5pm Mon-Fri. The Company: Our client develops and manufactures high performance polymers, for use in various applications. Location: This role is located near Hertford, easily commutable from North London, Hoddesdon, Harlow, Stevenage and surrounding areas. The Role: Your main duties will be: Production quality control. Non-hazardous and hazardous chemical handling. Laboratory equipment maintenance and any other machinery/equipment relevant to RnD activities. Maintain frequently used solutions and apparatus. Assist with design and development and testing of new products. Conduct experiments and ensure compliance with safety protocols. Accurately collect experimental data and ensure records are properly maintained. Your Background: The ideal candidate for this role will have the following skills and experience: Degree qualified in Chemistry or equivalent. Organised & methodical with excellent administration and document control skills. Highly motivated, with a 'can do' attitude. Ability to work under pressure and/or to strict deadlines. Able to drive to get to site. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDCH
Job Title: Senior Laboratory Research Scientist - Specialist Virology Researcher (SLRS) Details of the role : Full-time, permanent. Working pattern: Monday - Friday. Salary : From £45,7000 pa with benefits, subject to skills and experience Application closing date : 23/06/:59 GMT About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role Over the first year of the COVID-19 pandemic, the Crick developed a range of COVID-19 research platforms, including a unique high throughput live virus assay platform to quantify neutralising antibody activity against a range of SARS-CoV-2 variants in thousands of samples simultaneously. In collaboration with both clinical researchers and the Worldwide Influenza Centre (WIC) based at the Crick, we have used our microneutralisation platform to show at large scale how immunity to COVID-19 following vaccination and infection differs between healthy adults and clinically vulnerable patients. The Crick's COVID Surveillance Unit (CSU) was created in 2021 to run and improve upon this high-throughput live-virus assay pipeline. We are seeking to appoint a talented, collaborative, and self-motivated scientist to fill a full-time on-site laboratory position within the COVID Surveillance Unit (CSU) team. The team is responsible for the day to day running of a microneutralisation assay pipeline and you will either be capable of, or be willing to learn, all aspects of the pipeline to contribute to a dynamic and fluid team. You will need to horizon scan in the development of future assay platforms by interacting with Crick and external researchers and maintaining up to date knowledge of high-throughput technologies, virological and immunological techniques and advances. This is an opportunity to use your scientific and technical skills in a clinically vital enterprise and shape its development with your knowledge and expertise within one of the largest research institutes in Europe. What you will be doing As an SLRS at the Crick, you will: Ensuring the smooth operation of the neutralisation assay pipeline by conducting assays to the highest standards, liaising with all interested parties and team members ensuring clear communication. Managing workflows and ensuring neutralisation data is generated in a timely manner agreed with end users. The team must be adaptable and flexible in order to quickly adjust ongoing scheduled work to accommodate the unexpected. Providing experimental or technical support/assistance to other team members, and provide expertise feedback/input for the development, refinement, and troubleshooting of existing and novel methodologies. Isolation, propagation and genetic/molecular characterisation of newly emerging and reference SARS-CoV-2 and seasonal influenza viruses Managing and generating stocks of pseudoviruses and RG viruses for the neutralisation assay pipeline Applying understanding of the assay pipeline to adapting and/or developing new high throughput virological and immunological assays. Undertaking own research project, designing, and executing experiments /with strategic direction from the group head. About you The essential criteria you will bring PhD or equivalent qualification/experience in virology, immunology, or high throughput methodologies Extensive direct experience in cell-based assays, tissue culture, and immunofluorescence-staining techniques Previous experience in working with respiratory viruses, pseudoviruses, and RG viruses Previous experience in working with immunoassays Practical experience with a wide range of molecular and cell biology techniques Experience with data analysis and visualisation using R and/or Python To see the complete job description, click here . To learn more about team click here . About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold . We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open . We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial . We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and you will be asked as part of the process if you wish to apply under the scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas : Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme : Defined contribution pension with employer contributions of up to 16%. Health & Well-being : 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks : Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition : Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 18, 2025
Full time
Job Title: Senior Laboratory Research Scientist - Specialist Virology Researcher (SLRS) Details of the role : Full-time, permanent. Working pattern: Monday - Friday. Salary : From £45,7000 pa with benefits, subject to skills and experience Application closing date : 23/06/:59 GMT About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role Over the first year of the COVID-19 pandemic, the Crick developed a range of COVID-19 research platforms, including a unique high throughput live virus assay platform to quantify neutralising antibody activity against a range of SARS-CoV-2 variants in thousands of samples simultaneously. In collaboration with both clinical researchers and the Worldwide Influenza Centre (WIC) based at the Crick, we have used our microneutralisation platform to show at large scale how immunity to COVID-19 following vaccination and infection differs between healthy adults and clinically vulnerable patients. The Crick's COVID Surveillance Unit (CSU) was created in 2021 to run and improve upon this high-throughput live-virus assay pipeline. We are seeking to appoint a talented, collaborative, and self-motivated scientist to fill a full-time on-site laboratory position within the COVID Surveillance Unit (CSU) team. The team is responsible for the day to day running of a microneutralisation assay pipeline and you will either be capable of, or be willing to learn, all aspects of the pipeline to contribute to a dynamic and fluid team. You will need to horizon scan in the development of future assay platforms by interacting with Crick and external researchers and maintaining up to date knowledge of high-throughput technologies, virological and immunological techniques and advances. This is an opportunity to use your scientific and technical skills in a clinically vital enterprise and shape its development with your knowledge and expertise within one of the largest research institutes in Europe. What you will be doing As an SLRS at the Crick, you will: Ensuring the smooth operation of the neutralisation assay pipeline by conducting assays to the highest standards, liaising with all interested parties and team members ensuring clear communication. Managing workflows and ensuring neutralisation data is generated in a timely manner agreed with end users. The team must be adaptable and flexible in order to quickly adjust ongoing scheduled work to accommodate the unexpected. Providing experimental or technical support/assistance to other team members, and provide expertise feedback/input for the development, refinement, and troubleshooting of existing and novel methodologies. Isolation, propagation and genetic/molecular characterisation of newly emerging and reference SARS-CoV-2 and seasonal influenza viruses Managing and generating stocks of pseudoviruses and RG viruses for the neutralisation assay pipeline Applying understanding of the assay pipeline to adapting and/or developing new high throughput virological and immunological assays. Undertaking own research project, designing, and executing experiments /with strategic direction from the group head. About you The essential criteria you will bring PhD or equivalent qualification/experience in virology, immunology, or high throughput methodologies Extensive direct experience in cell-based assays, tissue culture, and immunofluorescence-staining techniques Previous experience in working with respiratory viruses, pseudoviruses, and RG viruses Previous experience in working with immunoassays Practical experience with a wide range of molecular and cell biology techniques Experience with data analysis and visualisation using R and/or Python To see the complete job description, click here . To learn more about team click here . About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold . We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open . We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial . We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and you will be asked as part of the process if you wish to apply under the scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas : Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme : Defined contribution pension with employer contributions of up to 16%. Health & Well-being : 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks : Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition : Comprehensive training, mentoring, and a pay structure based on skills and experience.
Job Title: Postdoctoral Project Research Scientist (PPRS) Details of the role : 2yr FTC, full-time. Working pattern: Monday - Friday. Salary : From £45,500 pa with benefits, subject to skills and experience Application closing date: 25/06/:59 GMT About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role The Miguel-Aliaga lab seek to understand how organs sense and react to their environment to maintain or change our physiology. To this end, they focus on the study of the intestinal tract; certain diets, microbes or internal states can cause it to grow or shrink. Current projects explore this plasticity across scales. Following previous work on the role that the shape of the gastrointestinal (GI) tract plays in health and disease in the fruit fly, we are now working on extending this work into analysis of human GI tract shape. We have adapted our methods to analyse GI tract shape in abdominal MRI scans and now wish to scale this up to a larger dataset. We have an approved project to work with the data of the UK Biobank - a large-scale biomedical database of volunteers from across the UK. This includes genetic data and whole-body MRI scans for 100,000 participants. We aim to investigate whether in humans, there is an underlying logic to GI tract shape and 3D organ arrangement which might vary in males and females, post-pregnancy and in disease such as Crohn's disease. We are looking for an ambitious and experienced image analyst for this computational post to develop AI-based image analysis methods to extract GI tract shape data from whole-body MRI scans. To learn more about team/Group Leader and projects currently being undertaken here . What you will be doing As a PPRS at the Crick, you will be: Developing image analysis tools for analysis of GI tract shape and volume from MRI scans Developing a neural network for the automation of segmentation of the GI tract from UK Biobank whole-body MRI scans Liaising with other lab members and collaborators to link analysis of GI tract shape features with other phenotype data and genetics in the UK Biobank Contributing to the preparation of scientific manuscripts, reports and presentations About you The essential criteria you will bring PhD in Developmental Biology, Cell Biology, Computational Biology or in the final stages of PhD submission Strong level of competence and experience of the use of deep learning for image analysis in large datasets, particularly image segmentation Strong level of competence in writing macros for ImageJ/FIJI and use of other languages such as R and Python for image analysis Experience of working with large 3D datasets such as MRI scans or microCT scans Experience of image segmentation Track record of writing papers as evidenced by publications or submitted manuscripts in refereed journals Evidence of data presentation at scientific meetings To see the complete job description, click here . About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold . We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open . We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial . We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and you will be asked as part of the process if you wish to apply under the scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas : Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being : 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance : Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks : Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition : Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 18, 2025
Full time
Job Title: Postdoctoral Project Research Scientist (PPRS) Details of the role : 2yr FTC, full-time. Working pattern: Monday - Friday. Salary : From £45,500 pa with benefits, subject to skills and experience Application closing date: 25/06/:59 GMT About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role The Miguel-Aliaga lab seek to understand how organs sense and react to their environment to maintain or change our physiology. To this end, they focus on the study of the intestinal tract; certain diets, microbes or internal states can cause it to grow or shrink. Current projects explore this plasticity across scales. Following previous work on the role that the shape of the gastrointestinal (GI) tract plays in health and disease in the fruit fly, we are now working on extending this work into analysis of human GI tract shape. We have adapted our methods to analyse GI tract shape in abdominal MRI scans and now wish to scale this up to a larger dataset. We have an approved project to work with the data of the UK Biobank - a large-scale biomedical database of volunteers from across the UK. This includes genetic data and whole-body MRI scans for 100,000 participants. We aim to investigate whether in humans, there is an underlying logic to GI tract shape and 3D organ arrangement which might vary in males and females, post-pregnancy and in disease such as Crohn's disease. We are looking for an ambitious and experienced image analyst for this computational post to develop AI-based image analysis methods to extract GI tract shape data from whole-body MRI scans. To learn more about team/Group Leader and projects currently being undertaken here . What you will be doing As a PPRS at the Crick, you will be: Developing image analysis tools for analysis of GI tract shape and volume from MRI scans Developing a neural network for the automation of segmentation of the GI tract from UK Biobank whole-body MRI scans Liaising with other lab members and collaborators to link analysis of GI tract shape features with other phenotype data and genetics in the UK Biobank Contributing to the preparation of scientific manuscripts, reports and presentations About you The essential criteria you will bring PhD in Developmental Biology, Cell Biology, Computational Biology or in the final stages of PhD submission Strong level of competence and experience of the use of deep learning for image analysis in large datasets, particularly image segmentation Strong level of competence in writing macros for ImageJ/FIJI and use of other languages such as R and Python for image analysis Experience of working with large 3D datasets such as MRI scans or microCT scans Experience of image segmentation Track record of writing papers as evidenced by publications or submitted manuscripts in refereed journals Evidence of data presentation at scientific meetings To see the complete job description, click here . About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold . We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open . We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial . We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and you will be asked as part of the process if you wish to apply under the scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas : Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being : 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance : Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks : Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition : Comprehensive training, mentoring, and a pay structure based on skills and experience.
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
Jun 18, 2025
Full time
Postdoctoral Fellow - Hill lab Reporting to: Caroline Hill, Head of Developmental Signalling Laboratory Contact term: This is a full-time, fixed term 4 years position on Crick terms and conditions of employment. About Us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to collaborate and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see . Their work seeks to understand how TGF-b family signalling pathways function normally in early vertebrate development and in adult untransformed cells, and how these signalling pathways are perturbed in disease, in particular in cancer and the Marfan-related syndromes. Work in the Hill laboratory exploits the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems (human and mouse ES cell/iPS cell models), and mouse cancer models and uses a very wide range of methodologies including developmental and cell biology, cancer biology, next generation sequencing and computational modelling. The Hill lab encourages creative and independent thinking and promotes excellent training and mentoring. The group currently comprises ten people - five postdocs, two PhD students, a clinical fellow, a master's student and a senior laboratory research scientist. For selected recent publications see: The Project Recent work in my lab has determined that mesoderm and endoderm specification in zebrafish embryos requires the interplay of two signalling pathways, Nodal and Fgf/Erk. We have shown that the distribution of endodermal progenitors results from a stochastic process where sustained Nodal signalling provides a competency window for the switching of bipotential progenitors to an endodermal fate. Switching is apparently stochastic and is inhibited by Fgf/Erk signalling. Cells that do not switch to the endodermal fate, differentiate to mesoderm. Thus, we hypothesise that short windows of Erk inactivity govern the switching to the endodermal fate and we have shown that these occur as cells undergo mitosis as a result of a phenomenon we are calling mitotic erasure. We now want to understand whether a similar mechanism controls the cell fate decision between mesoderm and definitive endoderm in humans, and if not, how this fate decision is controlled. To undertake this work, I am looking for a highly motivated postdoc with proven research abilities and an excellent publication record. The project will make use of human embryonic stem cells (hESCs) differentiated as 2D and 3D gastruloids. We will multiplex our novel Erk biosensor with live cell fate reporters to discover whether and how Erk signalling is involved in the cell fate decision between definitive endoderm and mesoderm. Furthermore, we will use multiomics scRNA-seq and scATAC-seq methodology, as well as whole genome CRISPR screening approaches to gain unbiased new insights into the mechanisms driving the specification of the mesodermal and endodermal lineages in humans. Postdoctoral Fellows at the Crick lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Key experience and competencies The post holder should embody and demonstrate our core Crick values: Bold; Imaginative; Open; Dynamic; Collegial Essential PhD in a relevant biological science Excellent knowledge and demonstrable practical experience of working with embryonic stem cells Extensive technical expertise in differentiating embryonic stem cells to different tissue types as 2D and 3D gastruloids Technical expertise in advanced live imaging Technical expertise in molecular biology Excellent track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings as talks and posters Strong organisational skills and thorough record-keeping Ability to work independently and also in a team Desirable Experience in 'omics techniques and bioinformatic analysis Experience in signal transduction research About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our team and you will be asked as part of the process if you wish to apply under the Disability Confident scheme. We will make reasonable adjustments if you need them. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure based on skills and experience.
CK Group are recruiting for a Technical Sales Specialist, to join a specialist company providing inspection, calibration and testing services, based in Staffordshire, on a permanent basis. You will be leading operations, for a dedicated team of scientists, making measurements on gas mixtures, using a range of bespoke gas chromatographs. Salary: £30,000 - £32,000 per annum, depending on experience. Your main duties will be (but not limited) to: Support the development and implementation of the business development strategy. Liaising with clients for the issue of quotations/proposals and receipt/acknowledgement of sales orders. Ensuring the contract and job databases are continually monitored and updated with in-date information. Liaising closely with production, laboratory services staff and logistics staff. Sales of laboratory services/products and site services to new and existing clients. Completing and submitting tender documents for high value major contracts. Your Background: The ideal candidate for this role will have: The job holder should hold a degree qualification in a science discipline. Good understanding of the principles of measurement. Excellent communication skills, both verbal and written. They should have sound organisational ability with the capacity to work individually or within the team. Benefits: Contributory company pension scheme. Performance-based bonus scheme. Company bonus scheme. 25 days holiday plus statutory bank holidays. Company sick pay scheme. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDCH
Jun 18, 2025
Full time
CK Group are recruiting for a Technical Sales Specialist, to join a specialist company providing inspection, calibration and testing services, based in Staffordshire, on a permanent basis. You will be leading operations, for a dedicated team of scientists, making measurements on gas mixtures, using a range of bespoke gas chromatographs. Salary: £30,000 - £32,000 per annum, depending on experience. Your main duties will be (but not limited) to: Support the development and implementation of the business development strategy. Liaising with clients for the issue of quotations/proposals and receipt/acknowledgement of sales orders. Ensuring the contract and job databases are continually monitored and updated with in-date information. Liaising closely with production, laboratory services staff and logistics staff. Sales of laboratory services/products and site services to new and existing clients. Completing and submitting tender documents for high value major contracts. Your Background: The ideal candidate for this role will have: The job holder should hold a degree qualification in a science discipline. Good understanding of the principles of measurement. Excellent communication skills, both verbal and written. They should have sound organisational ability with the capacity to work individually or within the team. Benefits: Contributory company pension scheme. Performance-based bonus scheme. Company bonus scheme. 25 days holiday plus statutory bank holidays. Company sick pay scheme. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDCH
Vitax Limited has an exciting opportunity for an experienced Technical Manager to join its technical team. This senior role involves in playing a key role the development of new garden retail products and overseeing all technical UK and EU regulatory compliance across Vitax's complete product portfolio including Plant Health & Protection, Biocides and Pesticides. This wide-ranging role requires a self-motivated individual with strong communication and analytical skills. Core knowledge, skills and abilities Product development: Lead the innovation, creation and development of new products within the garden retail portfolio. Assess feasibility of new products and liaison with active substance suppliers. Product formulations. Drive new commercial opportunities and deliver efficiencies across the product range. Oversee product trials. Responsibility for the health & safety of product formulations for both regulated and non-regulated products. Develop a long term, sustainable new product pipeline and continually review the viability and success of new and existing products. Technical & Compliance: Excellent technical knowledge and strong background in delivering innovative products in an FMCG environment. Experience of managing the registration/renewal processes for plant protection (PPP) and biocidal products. Ensure all products comply with PPP, Biocide, CLP & Fertiliser Regulations, and maintain MSDS and health & safety documentation. Liaise with various regulatory authorities and GLP laboratories. Keep up-to-date with regulatory guidance and forthcoming legislation and compliance issues. Oversee product labelling and classification. Represent the company on various taskforces and contribute to strategic discussions and regulatory submissions. Education: Degree in a relevant scientific discipline and at least five years, proven experience in a regulatory environment with knowledge of product labelling and compliance. Strong knowledge of pesticide and biocide regulations in the UK and EU. Ability to manage multiple projects at once and confidently work with both internal and external stakeholders. If you have excellent technical knowledge, experience of working within a complex regulatory environment and a drive to lead the creation and development of new products in a fast-moving retail sector, we'd love to hear from you. To apply for the role, please click below and send your CV
Jun 18, 2025
Full time
Vitax Limited has an exciting opportunity for an experienced Technical Manager to join its technical team. This senior role involves in playing a key role the development of new garden retail products and overseeing all technical UK and EU regulatory compliance across Vitax's complete product portfolio including Plant Health & Protection, Biocides and Pesticides. This wide-ranging role requires a self-motivated individual with strong communication and analytical skills. Core knowledge, skills and abilities Product development: Lead the innovation, creation and development of new products within the garden retail portfolio. Assess feasibility of new products and liaison with active substance suppliers. Product formulations. Drive new commercial opportunities and deliver efficiencies across the product range. Oversee product trials. Responsibility for the health & safety of product formulations for both regulated and non-regulated products. Develop a long term, sustainable new product pipeline and continually review the viability and success of new and existing products. Technical & Compliance: Excellent technical knowledge and strong background in delivering innovative products in an FMCG environment. Experience of managing the registration/renewal processes for plant protection (PPP) and biocidal products. Ensure all products comply with PPP, Biocide, CLP & Fertiliser Regulations, and maintain MSDS and health & safety documentation. Liaise with various regulatory authorities and GLP laboratories. Keep up-to-date with regulatory guidance and forthcoming legislation and compliance issues. Oversee product labelling and classification. Represent the company on various taskforces and contribute to strategic discussions and regulatory submissions. Education: Degree in a relevant scientific discipline and at least five years, proven experience in a regulatory environment with knowledge of product labelling and compliance. Strong knowledge of pesticide and biocide regulations in the UK and EU. Ability to manage multiple projects at once and confidently work with both internal and external stakeholders. If you have excellent technical knowledge, experience of working within a complex regulatory environment and a drive to lead the creation and development of new products in a fast-moving retail sector, we'd love to hear from you. To apply for the role, please click below and send your CV
CK Group are recruiting for a Clinical Trial Supplies Manager, to join a global pharmaceutical company, on a contract basis, for 6 months initially. Salary: Up to £28.76 per hour PAYE. Clinical Trial Supplies Manager Role: Collaborates with internal Global Clinical Supply Chain (GCSC) teams, external Customers & Service Providers Medical to ensure all needs are met. Defines, plans & communicates the clinical supply chain strategy in support of global clinical studies to promote optimal use. Demonstrates strong knowledge of GCSC processes when presenting at cross-functional meetings. Responsible for identifying and supporting strategies for continuous improvement. Influences clinical and development timelines, study design & country selection. Reviewing & providing input to draft clinical protocols, communicating timelines & investigational product strategies. Your Background : Degree in a relevant scientific subject or have equivalent working experience. Previous working experience in the pharmaceutical industry. Prior experience in a role focussed on Clinical Supplies/Development with global experience or equivalent experience. Strong knowledge of the global drug development process & global regulatory requirements. Strong knowledge of IVRS and CTMS systems. Company: Our client is the global leader in enabling pharma, biotech, and consumer health partners to optimize product development, launch, and full life-cycle supply for patients around the world. They have the goal of putting patients first and to help people around the world live better and healthier lives. Location: This is a remote role with travel to the Uxbridge office, 1-2 times a month. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDKA
Jun 18, 2025
Full time
CK Group are recruiting for a Clinical Trial Supplies Manager, to join a global pharmaceutical company, on a contract basis, for 6 months initially. Salary: Up to £28.76 per hour PAYE. Clinical Trial Supplies Manager Role: Collaborates with internal Global Clinical Supply Chain (GCSC) teams, external Customers & Service Providers Medical to ensure all needs are met. Defines, plans & communicates the clinical supply chain strategy in support of global clinical studies to promote optimal use. Demonstrates strong knowledge of GCSC processes when presenting at cross-functional meetings. Responsible for identifying and supporting strategies for continuous improvement. Influences clinical and development timelines, study design & country selection. Reviewing & providing input to draft clinical protocols, communicating timelines & investigational product strategies. Your Background : Degree in a relevant scientific subject or have equivalent working experience. Previous working experience in the pharmaceutical industry. Prior experience in a role focussed on Clinical Supplies/Development with global experience or equivalent experience. Strong knowledge of the global drug development process & global regulatory requirements. Strong knowledge of IVRS and CTMS systems. Company: Our client is the global leader in enabling pharma, biotech, and consumer health partners to optimize product development, launch, and full life-cycle supply for patients around the world. They have the goal of putting patients first and to help people around the world live better and healthier lives. Location: This is a remote role with travel to the Uxbridge office, 1-2 times a month. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDKA
CK Group are recruiting for an experienced Analytical Development Scientist, to join a Contract Research & Development and Manufacturing Organisation (CRDMO), working with innovator biotech and pharmaceutical companies globally, who are based in Macclesfield, on a permanent basis. Company: This company is well established and growing with R&D facilities globally. Location: The role is based on site in Macclesfield, Cheshire. Role: Support chemistry projects, through analytical lab-based work, develop, validate and carry out technical transfer of analytical methods and release analysis (GMP and non-GMP). Developing, troubleshooting and validating analytical methods. Planning and executing analytical work to meet project timelines with minimal supervision. Working within multi-functional project teams operating to tight deadlines. Able to work effectively to GMP quality standards. Opportunity to lead the analytical aspects of projects and lead a team of analysts to plan, supervise and execute analytical work to meet project timelines. Your Background: Educated to degree level or above in Chemistry, Analytical Chemistry or a related field. A background in Analytical Chemistry combined with demonstrated in-depth, hands-on expertise in HPLC/GC and experience of other analytical methodologies utilised to characterise APIs, intermediates and raw materials. Experience in other analytical methodologies such as techniques for identity or form determination (e.g. NMR, MS, IR, XRD). Understanding of GMP quality standards. Demonstrated analytical expertise supporting early, mid or late-phase route and process development of APIs, intermediates and raw materials. Experience in contracting analytical testing with third parties and leading communications with customers. Experience in regulatory requirements for the development and validation of LC/GC methods for content and the separation of impurities and degradation products in APIs including trace level analysis. Experience in out of specification and atypical result investigations. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDLS
Jun 18, 2025
Full time
CK Group are recruiting for an experienced Analytical Development Scientist, to join a Contract Research & Development and Manufacturing Organisation (CRDMO), working with innovator biotech and pharmaceutical companies globally, who are based in Macclesfield, on a permanent basis. Company: This company is well established and growing with R&D facilities globally. Location: The role is based on site in Macclesfield, Cheshire. Role: Support chemistry projects, through analytical lab-based work, develop, validate and carry out technical transfer of analytical methods and release analysis (GMP and non-GMP). Developing, troubleshooting and validating analytical methods. Planning and executing analytical work to meet project timelines with minimal supervision. Working within multi-functional project teams operating to tight deadlines. Able to work effectively to GMP quality standards. Opportunity to lead the analytical aspects of projects and lead a team of analysts to plan, supervise and execute analytical work to meet project timelines. Your Background: Educated to degree level or above in Chemistry, Analytical Chemistry or a related field. A background in Analytical Chemistry combined with demonstrated in-depth, hands-on expertise in HPLC/GC and experience of other analytical methodologies utilised to characterise APIs, intermediates and raw materials. Experience in other analytical methodologies such as techniques for identity or form determination (e.g. NMR, MS, IR, XRD). Understanding of GMP quality standards. Demonstrated analytical expertise supporting early, mid or late-phase route and process development of APIs, intermediates and raw materials. Experience in contracting analytical testing with third parties and leading communications with customers. Experience in regulatory requirements for the development and validation of LC/GC methods for content and the separation of impurities and degradation products in APIs including trace level analysis. Experience in out of specification and atypical result investigations. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDLS
CK Group are recruiting for a Shift Senior Site Chemist, to join a hazardous waste management company, based at their site near Birmingham, on a full time, permanent basis, for a salary of up to £32,000 per annum. Please note that this is a shift role, involving nights and working in the outdoors, not in a laboratory. As a Senior Site Chemist, you will be responsible in bringing value to the business, by accepting and inspecting all incoming assignments of Hazardous and Non-Hazardous Waste, by following the relevant regulations and site procedures. This is a role working 40 hpw, Monday- Friday. Location: The site is based near Birmingham and is commutable by Birmingham, Walsall, Wolverhampton, Lichfield and Stafford. As a Senior Site Chemist, the main purpose of your role will be: Ensuring all incoming consignments of wastes have appropriate paperwork. Responsible for the completion of waste safety checks to allow acceptance to site, storage safety and processing and/or onwards transfer. Responsible for the completion of regular sampling of received waste to then further supply to internal laboratory for analysis. Ensuring waste is routed such that costs are minimised whilst maintaining legality and compliance. Waste acceptance is recorded using the SAP system. Ensuring all waste is labelled correctly with all relevant information. Processing of waste as required to include bulking, sorting, segregating, listing and re-packing of wastes. Provide technical support to other members of staff on site. Complete relevant outgoing paperwork. As a Senior Site Chemist, you will have the following qualifications, skills and experience: Degree Level or HNC Qualification in Chemistry or a similar related field. Previous experience of the Waste Industry is essential. SAP experience is essential. Competent Microsoft Office user, in particular Excel. Willingness to work in outdoor conditions in a hazardous chemical environment undertaking a manual/hands on approach. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDCH
Jun 18, 2025
Full time
CK Group are recruiting for a Shift Senior Site Chemist, to join a hazardous waste management company, based at their site near Birmingham, on a full time, permanent basis, for a salary of up to £32,000 per annum. Please note that this is a shift role, involving nights and working in the outdoors, not in a laboratory. As a Senior Site Chemist, you will be responsible in bringing value to the business, by accepting and inspecting all incoming assignments of Hazardous and Non-Hazardous Waste, by following the relevant regulations and site procedures. This is a role working 40 hpw, Monday- Friday. Location: The site is based near Birmingham and is commutable by Birmingham, Walsall, Wolverhampton, Lichfield and Stafford. As a Senior Site Chemist, the main purpose of your role will be: Ensuring all incoming consignments of wastes have appropriate paperwork. Responsible for the completion of waste safety checks to allow acceptance to site, storage safety and processing and/or onwards transfer. Responsible for the completion of regular sampling of received waste to then further supply to internal laboratory for analysis. Ensuring waste is routed such that costs are minimised whilst maintaining legality and compliance. Waste acceptance is recorded using the SAP system. Ensuring all waste is labelled correctly with all relevant information. Processing of waste as required to include bulking, sorting, segregating, listing and re-packing of wastes. Provide technical support to other members of staff on site. Complete relevant outgoing paperwork. As a Senior Site Chemist, you will have the following qualifications, skills and experience: Degree Level or HNC Qualification in Chemistry or a similar related field. Previous experience of the Waste Industry is essential. SAP experience is essential. Competent Microsoft Office user, in particular Excel. Willingness to work in outdoor conditions in a hazardous chemical environment undertaking a manual/hands on approach. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDCH
CK Group are recruiting for a Laboratory Technician, to join a manufacturing company, that provides products to the agricultural industry, at their site based in Teesside, on a temporary basis for 6 months. The salary for this equates to £26,000 pa. Laboratory Technician main duties: Preparing and analysing exploration drill core samples. Keeping the Laboratory Manager informed of laboratory problems on a day-to-day basis. Developing good relationships with team members and internal customers. Following method statements and risk assessments. Working with other laboratory staff, to determine potential efficiency and performance improvements to workflows within the department. Your Background: The ideal candidate for this role will have the following skills and experience: GCSEs (or equivalent) in Science, Maths and English. Ability to handle large and heavy samples of drill core ( 20 kg) on a regular basis. IOSH Working Safely certificate (desirable). Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDCH
Jun 18, 2025
Full time
CK Group are recruiting for a Laboratory Technician, to join a manufacturing company, that provides products to the agricultural industry, at their site based in Teesside, on a temporary basis for 6 months. The salary for this equates to £26,000 pa. Laboratory Technician main duties: Preparing and analysing exploration drill core samples. Keeping the Laboratory Manager informed of laboratory problems on a day-to-day basis. Developing good relationships with team members and internal customers. Following method statements and risk assessments. Working with other laboratory staff, to determine potential efficiency and performance improvements to workflows within the department. Your Background: The ideal candidate for this role will have the following skills and experience: GCSEs (or equivalent) in Science, Maths and English. Ability to handle large and heavy samples of drill core ( 20 kg) on a regular basis. IOSH Working Safely certificate (desirable). Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDCH
CK Group are recruiting for a Procurement Category Manager, Facilities Management, to join a growing and exciting research facility in Oxford, on a permanent basis. This role will be hybrid, requiring you to be on-site for three days a week. The Company: A research-driven organisation led by talented scientists and entrepreneurs, dedicated to creating sustainable solutions for global challenges through interdisciplinary collaboration. This exciting new campus will feature state of art R&D facility, specialised laboratories, oncology clinics and focus on bridging scientific discovery with real-world applications by integrating expertise from various fields, including biomedical science, engineering, and public health. The Role: Our client is seeking an experienced and commercially savvy Procurement Category Manager, Facilities Management, to oversee Hard and Soft FM services and associated categories such as Laboratory Equipment and Services. Responsibilities: Developing and implementing category strategies for Facilities Management procurement, covering services such as mechanical & electrical (M&E) maintenance, cleaning, security, catering, workplace services, and minor construction works. Managing procurement for subcategories related to Facilities Management, including the sourcing and management of Laboratory Equipment (non-core scientific equipment supporting facilities and operations) and associated technical services. Leading competitive tendering processes, negotiations, supplier selection, and contract award activities, ensuring best value, service quality, and risk mitigation. Building and maintaining strong relationships with internal stakeholders including Facilities teams, Real Estate, Laboratory Managers, Health & Safety, Finance, and Legal departments. Conducting market and supplier analysis to identify opportunities for cost savings, service improvement, innovation, and sustainability. Your Background: Extensive procurement experience, including significant time in Facilities Management sourcing. Experience of procurement of laboratory equipment and services in an FM context. Experience of working in a biotechnology or pharmaceutical company environment. Proven experience of contract negotiation and preparation. A BSc in Procurement, Facilities Management, Supply Chain Management or similar. MCIPS qualified or working towards full membership. Salary: Competitive with an excellent benefits package. Apply : It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDCP
Jun 18, 2025
Full time
CK Group are recruiting for a Procurement Category Manager, Facilities Management, to join a growing and exciting research facility in Oxford, on a permanent basis. This role will be hybrid, requiring you to be on-site for three days a week. The Company: A research-driven organisation led by talented scientists and entrepreneurs, dedicated to creating sustainable solutions for global challenges through interdisciplinary collaboration. This exciting new campus will feature state of art R&D facility, specialised laboratories, oncology clinics and focus on bridging scientific discovery with real-world applications by integrating expertise from various fields, including biomedical science, engineering, and public health. The Role: Our client is seeking an experienced and commercially savvy Procurement Category Manager, Facilities Management, to oversee Hard and Soft FM services and associated categories such as Laboratory Equipment and Services. Responsibilities: Developing and implementing category strategies for Facilities Management procurement, covering services such as mechanical & electrical (M&E) maintenance, cleaning, security, catering, workplace services, and minor construction works. Managing procurement for subcategories related to Facilities Management, including the sourcing and management of Laboratory Equipment (non-core scientific equipment supporting facilities and operations) and associated technical services. Leading competitive tendering processes, negotiations, supplier selection, and contract award activities, ensuring best value, service quality, and risk mitigation. Building and maintaining strong relationships with internal stakeholders including Facilities teams, Real Estate, Laboratory Managers, Health & Safety, Finance, and Legal departments. Conducting market and supplier analysis to identify opportunities for cost savings, service improvement, innovation, and sustainability. Your Background: Extensive procurement experience, including significant time in Facilities Management sourcing. Experience of procurement of laboratory equipment and services in an FM context. Experience of working in a biotechnology or pharmaceutical company environment. Proven experience of contract negotiation and preparation. A BSc in Procurement, Facilities Management, Supply Chain Management or similar. MCIPS qualified or working towards full membership. Salary: Competitive with an excellent benefits package. Apply : It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence. If this position isn't suitable but you are looking for a new role, or if you are interested in seeing what opportunities are out there, head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news. INDCP
