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£36,720 to £42,000 per annum depending on qualifications and experience Applications are invited for a Research Scientist to join the Laboratory of Dr Hildebrand at Quadram Institute, Norwich, UK. Background: This post is part of the NERC project "Identifying novel microbial drivers to mitigate atmospheric methane emission". Methane is a powerful greenhouse gas, and we aim to reveal the role of ammonia oxidizing Archaea in methane oxidation in the environment. The project will determine how methane affects soil microbial communities, and how specific soil microorganisms respond to methane and metabolise it. The postholder will work with sequencing data derived from cultivated and natural soil microbiomes, to understand the role of prokaryotes (Archaea and Bacteria) in mitigating greenhouse gas emissions. The role: The project holder will use metagenomics (similar to doi:10.1038/s-6, 10 15314, 10.1186/s5-1) to profile both taxonomic and functional compositions of for SIP-enriched metagenomic and metatranscriptomic sequencing and functional-targeted amplicon sequencing data, interpreting experiments conducted in the laboratory of Prof Laura Lehtovirta-Morley. The bioinformatic tools will be developed to analyse and correct these data types, the statistical workflows established to interpret and understand how microorganisms respond to methane in both pristine and laboratory-based soil communities, building on tools available in the Hildebrand group. Long-term, this work will advance our understanding of biogeochemical cycling, contribute to reducing the impact of climate change by manipulating existing microbial communities, and understanding how healthy soil microbiomes are established, and maintained. The environment: The Hildebrand group uses metagenomics to research the diversity, community interactions, and evolution of microbes in communities using custom software solutions. The Lehtovirta-Morley group explores environmental microbiomes and biogeochemical cycling using both cultivation-independent and cultivation-dependent experiments. Both groups collaborate closely on microbial archaeal research in soils. The research is situated at the Norwich Research Park (NRP) UK, that encompasses the University of East Anglia, 4 BBSRC Institute, > 15 companies, 3,000 researchers and clinicians, 17,000 students. Norwich ranked in the top 10 for UK cities with a beautiful, historical town centre and an active gastropub & coffee aficionado scene. The applicant is expected to help in the supervision of junior group members and to represent the group at trainings. The applicant will have direct access to established PacBio/ONT, Hi-C and single cell sequencing facilities, as well as one of UK's largest HPC cluster at the NRP. The ideal candidate: The applicant needs to hold a PhD (or equivalent) in biology, bioinformatics, computer science or a related discipline with a background and/or interest in at least one of the following subjects: - Microbiomes & biodiversity - Metagenomics & patient cohorts - Ecology & evolution The ideal candidate will have a keen interest in soil microbiology and biogeochemical cycling, and experience in conducting scientific experiments independently, writing papers, presenting work and grant writing. Basic statistics and programming skills (either R, python, Perl, C++, or equivalent) is expected. Specialized skills will be taught and developed through mentorship and collaborations. Additional information: Salary on appointment will be within the range £36,720 to £42,000 per annum depending on qualifications and experience. This is a full-time post for a contract of 9 months, potentially extensible for a further 9 months. For further information and details of how to apply, please visit our website or contact the Human Resources team on or quoting reference . This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options. Interviews will likely be held around 14 July 2025. We are committed to equity, diversity and inclusion, and welcome applications from all sectors of society. The Institute values of Respect, Innovation, Collaboration and Excellence are at the heart of all we do, and we expect all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. About the Quadram Institute: The Quadram Institute is a new interdisciplinary research institute dedicated to understanding how food and microbes interact to promote health and prevent disease. Its mission is to deliver healthier lives through innovation in gut health, microbiology and food. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a state-of-the-art building on the Norwich Research Park. This is one of Europe's largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. ( ). The closing date for applications will be 8 July 2025. The Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer. Your message (please edit as appropriate) FindAPostDoc. Copyright All rights reserved.

MRC Laboratory Of Molecular Biology, UKRI Postdoctoral Scientist Salary £41,344 per annum 2 year fixed term MRC Laboratory of Molecular Biology, Cambridge, UK Applications are invited for a Postdoctoral Scientist position in the Group of Dr Phil Holliger. The Group are further developing an ultrahigh throughput technology called deep screening (Porebski et al. (2024) Nat. Biomed. Eng 8, 214-232). Candidates must have a PhD degree in a biological subject or be due to complete a PhD within 6 months. You should have experience in recombinant DNA technology, a strong background in molecular genetics techniques and an interest in technology development. Ideally, you will also have experience in in vitro evolution and next-generation sequencing techniques. Practical experience in bioinformatics and machine learning techniques will be considered a bonus. This is a two-year training and development position suitable for you if you have recently completed your doctoral studies, or you are looking to move into a new research discipline and/or need to further develop your research skills. Working with our world-class scientists, you will be working in an Institute renowned for its excellent scientific facilities and high-quality research. The LMB has a collaborative working culture and state-of-the-art building based on the Cambridge Biomedical Campus. We have on-site parking, cycle enclosures and excellent public transport links to the site. We have a staff restaurant with roof terrace and access to a Campus nursery and sports and social facilities. You will be eligible to join our defined benefit pension scheme with an employer contribution of 16%, holiday entitlement of 40.5 days (including bank holidays and privilege days) and a generous employee discount scheme. We are also committed to providing training and development opportunities including support towards role-related qualifications. The LMB is a world-class research institute within UK Research and Innovation (UKRI). UKRI is nine research councils, working together across all disciplines and sectors. More information can be found at and . If you are unable to apply online, please email us at . Closing date: 06/03/2025 Final appointments will be subject to a pre-employment screening. We actively support equality, diversity and inclusion in all our activities, processes and culture. We encourage applications from all sections of society. The LMB particularly welcomes women, minority ethnic and disabled candidates to apply for this vacancy as they are currently under-represented. We are a disability inclusive employer and encourage disabled people to apply for this role. You are very welcome to contact us for information about the application process and any adjustments you may require; .