Jobs in Structural Biology and Related Fields The Institute of Cancer Research (ICR), London, United Kingdom The Institute of Cancer Research (ICR) is one of the world's most influential cancer research institutes. Their mission is to make the discoveries that defeat cancer. They have a long and distinguished history of research with a major impact on the outcome for cancer patients. Thier unique partnership with The Royal Marsden NHS Foundation Trust (RMH) makes them the largest comprehensive cancer centre in Europe, performing high quality original basic research and translational studies. The ICR was ranked as the UK's top academic research centre in the 2008 Higher Education Funding Council Research Assessment Exercise. Based on their publication record, citations and impact they rank among the world's leading cancer research centres. The Cancer Research UK Cancer Therapeutics Unit (CTU), embedded within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Cancer Therapeutics Unit's exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible, including medicinal chemistry, biology, drug metabolism and clinical specialists. A postdoctoral position for a protein crystallographer is available in Dr Rob van Montfort's Hit Discovery and Structural Design Team within the CTU (Ref:). The Post-doc will be involved in high-throughput X-ray crystallography, fragment-based screening and structure-based drug design and will be responsible for crystallisation and structural analysis of protein-ligand complexes from one of the CTU's drug discovery programmes. The successful candidate will interact closely with the biology, computational chemistry and medicinal chemistry teams at the CTU as well as with the protein crystallographers in the Division of Structural Biology in which the crystallography efforts of Dr van Montfort's team are embedded. Therefore the successful candidate will be expected to work across the two sites in Chelsea, London and Sutton, Surrey. Applicants must have a PhD in a biological or physical science, and experience in macromolecular crystallography (to include protein biochemistry, protein crystallisation, & protein crystallography). Experience in molecular biology and/or structure-based drug design will be an advantage. The starting salary for the position will be in the range £28,425 to £40,628 p.a. inclusive (based on previous post-doctoral experience) and the post is offered initially on a fixed term contract of 1 year in the first instance. Closing date: 30 September 2013.
Sep 14, 2026
Full time
Jobs in Structural Biology and Related Fields The Institute of Cancer Research (ICR), London, United Kingdom The Institute of Cancer Research (ICR) is one of the world's most influential cancer research institutes. Their mission is to make the discoveries that defeat cancer. They have a long and distinguished history of research with a major impact on the outcome for cancer patients. Thier unique partnership with The Royal Marsden NHS Foundation Trust (RMH) makes them the largest comprehensive cancer centre in Europe, performing high quality original basic research and translational studies. The ICR was ranked as the UK's top academic research centre in the 2008 Higher Education Funding Council Research Assessment Exercise. Based on their publication record, citations and impact they rank among the world's leading cancer research centres. The Cancer Research UK Cancer Therapeutics Unit (CTU), embedded within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Cancer Therapeutics Unit's exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible, including medicinal chemistry, biology, drug metabolism and clinical specialists. A postdoctoral position for a protein crystallographer is available in Dr Rob van Montfort's Hit Discovery and Structural Design Team within the CTU (Ref:). The Post-doc will be involved in high-throughput X-ray crystallography, fragment-based screening and structure-based drug design and will be responsible for crystallisation and structural analysis of protein-ligand complexes from one of the CTU's drug discovery programmes. The successful candidate will interact closely with the biology, computational chemistry and medicinal chemistry teams at the CTU as well as with the protein crystallographers in the Division of Structural Biology in which the crystallography efforts of Dr van Montfort's team are embedded. Therefore the successful candidate will be expected to work across the two sites in Chelsea, London and Sutton, Surrey. Applicants must have a PhD in a biological or physical science, and experience in macromolecular crystallography (to include protein biochemistry, protein crystallisation, & protein crystallography). Experience in molecular biology and/or structure-based drug design will be an advantage. The starting salary for the position will be in the range £28,425 to £40,628 p.a. inclusive (based on previous post-doctoral experience) and the post is offered initially on a fixed term contract of 1 year in the first instance. Closing date: 30 September 2013.
The University of Oxford invites applications for two Postdoctoral Research Associates to study the Tat protein transporter. The project aims to determine high-resolution structures of TatC in complex with other Tat components and to perform related biochemical analyses. Applicants should have a PhD in Biochemistry or Structural Biology or a related discipline, with expertise in protein purification, structural methods, and membrane protein biochemistry; the appointment is for up to 48 months
Sep 14, 2026
Full time
The University of Oxford invites applications for two Postdoctoral Research Associates to study the Tat protein transporter. The project aims to determine high-resolution structures of TatC in complex with other Tat components and to perform related biochemical analyses. Applicants should have a PhD in Biochemistry or Structural Biology or a related discipline, with expertise in protein purification, structural methods, and membrane protein biochemistry; the appointment is for up to 48 months
Jobs in Structural Biology and Related Fields Postdoctoral Position London, United Kingdom A PostDoctoral position is immediately available in Alessandro Vannini's lab at the Institute of Cancer Research in central London to structurally and functionally characterise large multi-subunit complexes involved in eukaryotic transcription (). We are looking for highly motivated and creative individuals with a strong interest in structural characterization of multi-subunit complexes. We currently employ single particle electron microscopy analysis and x-ray crystallography, as well as biochemical and biochemical analysis, to elucidate the role of the RNA Polymerase III transcription apparatus in cancer and other fundamental cellular processes (). The lab is well equipped with a fleet of AKTAs (including a brand new AKTA Pure) and have access to divisional managed facilities for protein crystallography (Bruker Microstar and CCD detector and crystallisation robots), cryo-electron microscopy (FEI Tecnai F20 and T12), and protein production with expertise in multi-subunit expression (insect cell, yeast and bacterial expression, including a 60 L fermentor). The Division is also well equipped with equipment for biophysical analysis (e.g. ITC, fluorescence, multi-angle light scattering). Applicants should possess a PhD (or equivalent) in biochemistry or molecular biology with a sound knowledge of multi-subunit complex production and purification. Experience in purification of recombinant and/or endogenous proteins for structural biology analysis is essential for this post. Experience in protein crystallography and/or single particle electron microscopy would be desirable. Individuals with a strong background in biochemical characterization of transcription machineries wishing to learn structural biology techniques will be taken into serious consideration. The lab is located in the heart of central London, in the vibrant area of South Kensington. Appointment will be on Fixed Term Contract for 2 years in the first instance, with a starting salary in the range of £28,087 to £34,529 p.a. inclusive (based on previous post-doctoral experience). Job Ref. No. Closing Date: 15/09/2013
Sep 13, 2026
Full time
Jobs in Structural Biology and Related Fields Postdoctoral Position London, United Kingdom A PostDoctoral position is immediately available in Alessandro Vannini's lab at the Institute of Cancer Research in central London to structurally and functionally characterise large multi-subunit complexes involved in eukaryotic transcription (). We are looking for highly motivated and creative individuals with a strong interest in structural characterization of multi-subunit complexes. We currently employ single particle electron microscopy analysis and x-ray crystallography, as well as biochemical and biochemical analysis, to elucidate the role of the RNA Polymerase III transcription apparatus in cancer and other fundamental cellular processes (). The lab is well equipped with a fleet of AKTAs (including a brand new AKTA Pure) and have access to divisional managed facilities for protein crystallography (Bruker Microstar and CCD detector and crystallisation robots), cryo-electron microscopy (FEI Tecnai F20 and T12), and protein production with expertise in multi-subunit expression (insect cell, yeast and bacterial expression, including a 60 L fermentor). The Division is also well equipped with equipment for biophysical analysis (e.g. ITC, fluorescence, multi-angle light scattering). Applicants should possess a PhD (or equivalent) in biochemistry or molecular biology with a sound knowledge of multi-subunit complex production and purification. Experience in purification of recombinant and/or endogenous proteins for structural biology analysis is essential for this post. Experience in protein crystallography and/or single particle electron microscopy would be desirable. Individuals with a strong background in biochemical characterization of transcription machineries wishing to learn structural biology techniques will be taken into serious consideration. The lab is located in the heart of central London, in the vibrant area of South Kensington. Appointment will be on Fixed Term Contract for 2 years in the first instance, with a starting salary in the range of £28,087 to £34,529 p.a. inclusive (based on previous post-doctoral experience). Job Ref. No. Closing Date: 15/09/2013
Jobs in Structural Biology and Related Fields Postdoctoral position in AI for Molecular Modelling Department of Computer Science - Brunel University of London Contract Type: Fixed-term until 30/11/2028 The Research Fellow will deliver the computational component of the project through protein structure modelling, molecular docking and detailed analysis of protein-ligand interactions. They will integrate these results with receptor-interaction data generated by the experimental collaborators at the University of Southampton to develop and evaluate artificial intelligence (AI) methods for predicting chemical binding and species sensitivity. Preference will be given to candidates with knowledge and experience of protein molecular modelling, protein-ligand docking, machine learning methods for computational biology, and software development in Python. Closing date for applications: 21st September 2026 Interviews will take place during the week of 12th October 2026 online.
Sep 12, 2026
Full time
Jobs in Structural Biology and Related Fields Postdoctoral position in AI for Molecular Modelling Department of Computer Science - Brunel University of London Contract Type: Fixed-term until 30/11/2028 The Research Fellow will deliver the computational component of the project through protein structure modelling, molecular docking and detailed analysis of protein-ligand interactions. They will integrate these results with receptor-interaction data generated by the experimental collaborators at the University of Southampton to develop and evaluate artificial intelligence (AI) methods for predicting chemical binding and species sensitivity. Preference will be given to candidates with knowledge and experience of protein molecular modelling, protein-ligand docking, machine learning methods for computational biology, and software development in Python. Closing date for applications: 21st September 2026 Interviews will take place during the week of 12th October 2026 online.