About Prima Mente Prima Mente is a frontier biology AI lab. We generate our own data, build general purpose biological foundation models, and translate discoveries into research and clinical outcomes. Our first goal is to tackle the brain: to deeply understand it, protect it from neurological disease, and enhance it in health. Our team of AI researchers, experimentalists, clinicians, and operators is based in London, San Francisco and Dubai. Role focus - GPU/CPU-accelerated bioinformatics Architect, build, and own scalable production pipelines that process multi-omics data for AI model development, moving from hypothesis to patent-ready results in months, not years. Key Tasks Design and implement GPU/CPU-native bioinformatics pipelines using Flyte and/or Nextflow for multi-omics data processing at scale (1000+ samples) Optimising cost and performance, leveraging GPU/CPU acceleration where it matters Work with experimental and machine learning teams to confirm and refine computational findings, and to ensure processing aligns with model needs Cloud infrastructure Develop and manage specific external research collaborations with academic and industrial partners Expected Growth In 1 month you are deploying workflows on GPU/CPU-accelerated cloud infrastructure to process your own multi-omic experiments, while establishing relationships with AI/ML and wet lab teams to understand their requirements. In 3 months you directly own multiple optimised GPU/CPU-native pipelines processing in the order of 1,000s of samples with high speed improvements and significantly reduced costs, generating publication and patent-ready results. In 6 months your pipelines run in production as automatised as possible feeding AI model training daily, you're co-designing experiments with AI/ML engineers and you're leading technical execution on external collaborations with industrial and/or academic partners. Who You Are You want to redefine what's possible at the frontier of AI and biology. You're an engineer, not an analyst. You thrive pushing the boundaries of performance and efficiency and enjoy architecting the systems and making multiple fast technical decisions. You iterate and move fast. We don't expect you to check every box. Strong applicants often have depth in some of these and interest in growing into others. Ideal experience Knowledge of GPU/CPU computing backbone, whether directly through GPU/CPU-accelerated bioinformatics (e.g., NVIDIA Parabricks, Clara, Rapids, etc.) or through the ability to identify GPU vs. CPU optimisation in other contexts Operational software engineering skills: the ability to write high-quality code to be the backbone of our software stack. Strong working knowledge with cloud computing environments, including but not limited to AWS and GCP First hand deep experience with at least 2 3 large omics types (genomics, transcriptomics, chromatin accessibility, DNA methylation, histone modifications profiling, etc.) Experience with end to end tools used to process multi omic data from raw data all the way to analytical outputs. Good working knowledge of workflow managers (e.g., Flyte, Nextflow, Snakemake). Familiar with data wrangling, analysis, and visualisation libraries using Python (preferable), R or Julia. Strong data engineering knowledge, including but not limited to experience with Spark, Hadoop, NoSQL. Location Based in San Francisco, US or London, UK. We support O1 (US) and GTV (UK) visa applications. Culture Insight What we are doing is extremely hard. Prima Mente is for great people. We are team players who appreciate challenges, want to be hands on, and thrive on curiosity by throwing away assumptions. We are focused on excellence at pace and huge personal growth. We are strong communicators who are highly disciplined and rigorous. Prima Mente operates with a flat organizational structure. We gain and share knowledge by contributing to multiple opportunities. Leadership is given to those who show initiative and consistently deliver excellence. We arrange our lives so we can work in person as much as possible. Our Values Exceptional performance at exceptional pace The solutions we build demand uncompromising quality and rigour. The problems we are solving are grave and present. Inquisitive discovery We embrace curiosity and creativity. Every question is a path to a transformational breakthrough. Radical candour We practice unwavering honesty and transparency in all our challenges and interactions. Purposeful individuality Every individual in our team is celebrated for their identity, uniqueness, and experiences. We are invested in each one's bespoke personal development. Nurturing individuality will supercharge our collective purpose and spirit. Patient impact at scale We have a steadfast commitment to improve the health and well being of patients globally. Every experiment run, every dataset analysed, and every innovation developed, is a step towards achieving a scalable impact.
Jan 27, 2026
Full time
About Prima Mente Prima Mente is a frontier biology AI lab. We generate our own data, build general purpose biological foundation models, and translate discoveries into research and clinical outcomes. Our first goal is to tackle the brain: to deeply understand it, protect it from neurological disease, and enhance it in health. Our team of AI researchers, experimentalists, clinicians, and operators is based in London, San Francisco and Dubai. Role focus - GPU/CPU-accelerated bioinformatics Architect, build, and own scalable production pipelines that process multi-omics data for AI model development, moving from hypothesis to patent-ready results in months, not years. Key Tasks Design and implement GPU/CPU-native bioinformatics pipelines using Flyte and/or Nextflow for multi-omics data processing at scale (1000+ samples) Optimising cost and performance, leveraging GPU/CPU acceleration where it matters Work with experimental and machine learning teams to confirm and refine computational findings, and to ensure processing aligns with model needs Cloud infrastructure Develop and manage specific external research collaborations with academic and industrial partners Expected Growth In 1 month you are deploying workflows on GPU/CPU-accelerated cloud infrastructure to process your own multi-omic experiments, while establishing relationships with AI/ML and wet lab teams to understand their requirements. In 3 months you directly own multiple optimised GPU/CPU-native pipelines processing in the order of 1,000s of samples with high speed improvements and significantly reduced costs, generating publication and patent-ready results. In 6 months your pipelines run in production as automatised as possible feeding AI model training daily, you're co-designing experiments with AI/ML engineers and you're leading technical execution on external collaborations with industrial and/or academic partners. Who You Are You want to redefine what's possible at the frontier of AI and biology. You're an engineer, not an analyst. You thrive pushing the boundaries of performance and efficiency and enjoy architecting the systems and making multiple fast technical decisions. You iterate and move fast. We don't expect you to check every box. Strong applicants often have depth in some of these and interest in growing into others. Ideal experience Knowledge of GPU/CPU computing backbone, whether directly through GPU/CPU-accelerated bioinformatics (e.g., NVIDIA Parabricks, Clara, Rapids, etc.) or through the ability to identify GPU vs. CPU optimisation in other contexts Operational software engineering skills: the ability to write high-quality code to be the backbone of our software stack. Strong working knowledge with cloud computing environments, including but not limited to AWS and GCP First hand deep experience with at least 2 3 large omics types (genomics, transcriptomics, chromatin accessibility, DNA methylation, histone modifications profiling, etc.) Experience with end to end tools used to process multi omic data from raw data all the way to analytical outputs. Good working knowledge of workflow managers (e.g., Flyte, Nextflow, Snakemake). Familiar with data wrangling, analysis, and visualisation libraries using Python (preferable), R or Julia. Strong data engineering knowledge, including but not limited to experience with Spark, Hadoop, NoSQL. Location Based in San Francisco, US or London, UK. We support O1 (US) and GTV (UK) visa applications. Culture Insight What we are doing is extremely hard. Prima Mente is for great people. We are team players who appreciate challenges, want to be hands on, and thrive on curiosity by throwing away assumptions. We are focused on excellence at pace and huge personal growth. We are strong communicators who are highly disciplined and rigorous. Prima Mente operates with a flat organizational structure. We gain and share knowledge by contributing to multiple opportunities. Leadership is given to those who show initiative and consistently deliver excellence. We arrange our lives so we can work in person as much as possible. Our Values Exceptional performance at exceptional pace The solutions we build demand uncompromising quality and rigour. The problems we are solving are grave and present. Inquisitive discovery We embrace curiosity and creativity. Every question is a path to a transformational breakthrough. Radical candour We practice unwavering honesty and transparency in all our challenges and interactions. Purposeful individuality Every individual in our team is celebrated for their identity, uniqueness, and experiences. We are invested in each one's bespoke personal development. Nurturing individuality will supercharge our collective purpose and spirit. Patient impact at scale We have a steadfast commitment to improve the health and well being of patients globally. Every experiment run, every dataset analysed, and every innovation developed, is a step towards achieving a scalable impact.
A leading AI lab is seeking a specialist in bioinformatics to architect and build scalable production pipelines for multi-omics data processing. The ideal candidate will have in-depth knowledge of GPU/CPU computing, operational software engineering skills, and familiarity with cloud computing environments. You will collaborate with teams to optimize performance and ensure projects meet their AI model needs. This position is a fantastic opportunity for individuals eager to push boundaries and make substantial impacts in AI-driven biological research.
Jan 27, 2026
Full time
A leading AI lab is seeking a specialist in bioinformatics to architect and build scalable production pipelines for multi-omics data processing. The ideal candidate will have in-depth knowledge of GPU/CPU computing, operational software engineering skills, and familiarity with cloud computing environments. You will collaborate with teams to optimize performance and ensure projects meet their AI model needs. This position is a fantastic opportunity for individuals eager to push boundaries and make substantial impacts in AI-driven biological research.
A leading AI laboratory in London seeks a candidate for a multi-omics role, focusing on marker and target discovery related to neurological diseases. The successful applicant will manage experimental hypotheses, curate datasets, and develop bioinformatics pipelines. Ideal candidates should have experience in multi-omic data analysis, operational software engineering, and cloud computing. The lab values curiosity, collaboration, and exceptional performance, offering opportunities for rigorous personal development.
Jan 26, 2026
Full time
A leading AI laboratory in London seeks a candidate for a multi-omics role, focusing on marker and target discovery related to neurological diseases. The successful applicant will manage experimental hypotheses, curate datasets, and develop bioinformatics pipelines. Ideal candidates should have experience in multi-omic data analysis, operational software engineering, and cloud computing. The lab values curiosity, collaboration, and exceptional performance, offering opportunities for rigorous personal development.
A cutting-edge biotechnology AI lab is looking for an expert focused on advancing our understanding of neurological diseases through virtual cell models. The role demands robust experience with cellular state representation and multi-omic data, alongside operational software engineering skills. You will drive analyses, develop pipelines, and collaborate with academic and industrial partners. Ideal candidates should thrive in a dynamic, curiosity-driven team and have a passion for impactful health advancements.
Jan 26, 2026
Full time
A cutting-edge biotechnology AI lab is looking for an expert focused on advancing our understanding of neurological diseases through virtual cell models. The role demands robust experience with cellular state representation and multi-omic data, alongside operational software engineering skills. You will drive analyses, develop pipelines, and collaborate with academic and industrial partners. Ideal candidates should thrive in a dynamic, curiosity-driven team and have a passion for impactful health advancements.
About Prima Mente Prima Mente is a frontier biology AI lab. We generate our own data, build general purpose biological foundation models, and translate discoveries into research and clinical outcomes. Our first goal is to tackle the brain: to deeply understand it, protect it from neurological disease, and enhance it in health. Our team of AI researchers, experimentalists, clinicians, and operators is based in London, San Francisco and Dubai. Role focus - Multi-omics Clearly articulate and interrogate meaningful biological hypotheses for marker and target discovery related to neurological diseases. Key Tasks Set up and framework experimental hypotheses focussed on available datasets and models, with downstream evaluation criteria to assess performance. Identify and curate public and proprietary datasets across different multi-omic, multi-modal types. QC and data analysis. Multi-omic bioinformatics pipeline development. Cloud infrastructure. Feature engineering and dataset preparation for downstream machine learning as well as foundational AI training and application. Work with experimental and machine learning teams to confirm and refine computational findings. Develop and manage specific external research collaborations with academic and industrial partners specific to AD biology. Expected Growth In 1 month you will be responsible for your own analysis and experiments on our cloud compute environment, involving creating an ad hoc nextflow or flyte workflow to massively process your data. In 3 months you directly own and have created an optimised analysis or data processing pipeline and generated results fit for patent and publication. In 6 months you have integrated your research into our AI models. Who You Are You want to redefine what's possible at the frontier of AI and biology. You have experience uncovering novel biology from multi-omic multi-modal data from Alzheimer's patients as well as top tier publications and / or patents. We don't expect you to check every box. Strong applicants often have depth in some of these and interest in growing into others. Ideal experience Top tier publications. Patent experience. First-hand experience with generating biological insights from biological data (genomics, epigenetics, transcriptomics, proteomics, ATAC-Seq). Operational software engineering skills: the ability to write high-quality code to be the backbone of our software stack. Experience with end-to-end tools used to process multi-omic data from raw data all the way to analytical outputs. Good working knowledge of workflow managers, including but not limited to NextFlow. Expertise with statistical approaches applied to evaluating biological datasets. Strong working knowledge with cloud computing environments, including but not limited to AWS. Domain knowledge with advanced artificial intelligence approaches and experience applying them to a biological context. Familiar with data wrangling, analysis, and visualisation libraries using Python (preferable), R or Julia. Strong data engineering knowledge, including but not limited to experience with Spark, Hadoop, NoSQL. Location Based in San Francisco, US or London, UK. We support O1 (US) and GTV (UK) visa applications. Culture Insight What we are doing is extremely hard. Prima Mente is for great people. We are team players who appreciate challenges, want to be hands-on, and thrive on curiosity by throwing away assumptions. We are focused on excellence at pace and huge personal growth. We are strong communicators who are highly disciplined and rigorous. Prima Mente operates with a flat organizational structure. We gain and share knowledge by contributing to multiple opportunities. Leadership is given to those who show initiative and consistently deliver excellence. We arrange our lives so we can work in person as much as possible. Our Values Exceptional performance at exceptional pace The solutions we build demand uncompromising quality and rigour. The problems we are solving are grave and present. Inquisitive discovery We embrace curiosity and creativity. Every question is a path to a transformational breakthrough. Radical candour We practice unwavering honesty and transparency in all our challenges and interactions. Purposeful individuality Every individual in our team is celebrated for their identity, uniqueness, and experiences. We are invested in each one's bespoke personal development. Nurturing individuality will supercharge our collective purpose and spirit. Patient impact at scale We have a steadfast commitment to improve the health and well-being of patients globally. Every experiment run, every dataset analysed, and every innovation developed, is a step towards achieving a scalable impact.
Jan 26, 2026
Full time
About Prima Mente Prima Mente is a frontier biology AI lab. We generate our own data, build general purpose biological foundation models, and translate discoveries into research and clinical outcomes. Our first goal is to tackle the brain: to deeply understand it, protect it from neurological disease, and enhance it in health. Our team of AI researchers, experimentalists, clinicians, and operators is based in London, San Francisco and Dubai. Role focus - Multi-omics Clearly articulate and interrogate meaningful biological hypotheses for marker and target discovery related to neurological diseases. Key Tasks Set up and framework experimental hypotheses focussed on available datasets and models, with downstream evaluation criteria to assess performance. Identify and curate public and proprietary datasets across different multi-omic, multi-modal types. QC and data analysis. Multi-omic bioinformatics pipeline development. Cloud infrastructure. Feature engineering and dataset preparation for downstream machine learning as well as foundational AI training and application. Work with experimental and machine learning teams to confirm and refine computational findings. Develop and manage specific external research collaborations with academic and industrial partners specific to AD biology. Expected Growth In 1 month you will be responsible for your own analysis and experiments on our cloud compute environment, involving creating an ad hoc nextflow or flyte workflow to massively process your data. In 3 months you directly own and have created an optimised analysis or data processing pipeline and generated results fit for patent and publication. In 6 months you have integrated your research into our AI models. Who You Are You want to redefine what's possible at the frontier of AI and biology. You have experience uncovering novel biology from multi-omic multi-modal data from Alzheimer's patients as well as top tier publications and / or patents. We don't expect you to check every box. Strong applicants often have depth in some of these and interest in growing into others. Ideal experience Top tier publications. Patent experience. First-hand experience with generating biological insights from biological data (genomics, epigenetics, transcriptomics, proteomics, ATAC-Seq). Operational software engineering skills: the ability to write high-quality code to be the backbone of our software stack. Experience with end-to-end tools used to process multi-omic data from raw data all the way to analytical outputs. Good working knowledge of workflow managers, including but not limited to NextFlow. Expertise with statistical approaches applied to evaluating biological datasets. Strong working knowledge with cloud computing environments, including but not limited to AWS. Domain knowledge with advanced artificial intelligence approaches and experience applying them to a biological context. Familiar with data wrangling, analysis, and visualisation libraries using Python (preferable), R or Julia. Strong data engineering knowledge, including but not limited to experience with Spark, Hadoop, NoSQL. Location Based in San Francisco, US or London, UK. We support O1 (US) and GTV (UK) visa applications. Culture Insight What we are doing is extremely hard. Prima Mente is for great people. We are team players who appreciate challenges, want to be hands-on, and thrive on curiosity by throwing away assumptions. We are focused on excellence at pace and huge personal growth. We are strong communicators who are highly disciplined and rigorous. Prima Mente operates with a flat organizational structure. We gain and share knowledge by contributing to multiple opportunities. Leadership is given to those who show initiative and consistently deliver excellence. We arrange our lives so we can work in person as much as possible. Our Values Exceptional performance at exceptional pace The solutions we build demand uncompromising quality and rigour. The problems we are solving are grave and present. Inquisitive discovery We embrace curiosity and creativity. Every question is a path to a transformational breakthrough. Radical candour We practice unwavering honesty and transparency in all our challenges and interactions. Purposeful individuality Every individual in our team is celebrated for their identity, uniqueness, and experiences. We are invested in each one's bespoke personal development. Nurturing individuality will supercharge our collective purpose and spirit. Patient impact at scale We have a steadfast commitment to improve the health and well-being of patients globally. Every experiment run, every dataset analysed, and every innovation developed, is a step towards achieving a scalable impact.