Optibrium

Senior or Principal Scientist - 3D Molecular Modelling Founded in 2009 and headquartered in Cambridge, UK, Optibrium develops software and novel technologies to improve the efficiency and productivity of drug discovery. Our solutions support industry-leading research for a global customer base, including top ten pharma and innovative biotech companies. Optibrium software solutions include: StarDrop - A complete package of fully integrated software for multi-objective small molecule design, optimisation, and data analysis; Cerella - A unique platform for the imputation of drug discovery data, revealing insights into the best compounds and most valuable experiments; BioPharmics - A fast, robust, and accurate 3D ligand- and structure-based design platform that scales from small molecules to large macrocycles. With a strong track record of translating peer reviewed science into successful products and a growing blue chip customer base for BioPharmics, we are recruiting a Senior or Principal Scientist - 3D Molecular Modelling to help customers achieve challenging drug discovery objectives and maximise the value of our software. About the Role As a Senior or Principal Scientist you will: Apply 3D structure based and ligand based design approaches to lead discovery and optimisation Support current and prospective customers in the effective use of BioPharmics, working with the commercial team to communicate its value clearly and scientifically Use NMR and X ray crystallography data in combination with the BioPharmics modelling methods Provide guidance on the development of the BioPharmics platform by identifying unmet customer needs and translating them into product and research opportunities Represent Optibrium's science and products at conferences, workshops, and customer meetings About You The ideal candidate will have the following experience: PhD in computational chemistry, computer science, chemistry, biophysics, or a related discipline Strong understanding of structure based and ligand based drug design, ideally including experience with macrocycles and peptides Experience with molecular modelling and visualisation platforms, e.g., PyMOL and MOE Experience with structural data (NMR and X ray crystallography) applied to molecular design problems A track record of high quality peer reviewed publications and conference presentations The ability to work effectively with customers, collaborators, and cross functional teams What We Offer We offer hybrid & flexible working, a competitive base salary, pension contribution, employee private medical and dental cover, life assurance, corporate gym discount and cycle to work scheme.

Senior or Principal Scientist - 3D Molecular Modelling Founded in 2009 and headquartered in Cambridge, UK, Optibrium develops software and novel technologies to improve the efficiency and productivity of drug discovery. Our solutions support industry-leading research for a global customer base, including top ten pharma and innovative biotech companies. Optibrium software solutions include: StarDrop - A complete package of fully integrated software for multi-objective small molecule design, optimisation, and data analysis; Cerella - A unique platform for the imputation of drug discovery data, revealing insights into the best compounds and most valuable experiments; BioPharmics - A fast, robust, and accurate 3D ligand- and structure-based design platform that scales from small molecules to large macrocycles. With a strong track record of translating peer reviewed science into successful products and a growing blue chip customer base for BioPharmics, we are recruiting a Senior or Principal Scientist - 3D Molecular Modelling to help customers achieve challenging drug discovery objectives and maximise the value of our software. About the Role As a Senior or Principal Scientist you will: Apply 3D structure based and ligand based design approaches to lead discovery and optimisation Support current and prospective customers in the effective use of BioPharmics, working with the commercial team to communicate its value clearly and scientifically Use NMR and X ray crystallography data in combination with the BioPharmics modelling methods Provide guidance on the development of the BioPharmics platform by identifying unmet customer needs and translating them into product and research opportunities Represent Optibrium's science and products at conferences, workshops, and customer meetings About You The ideal candidate will have the following experience: PhD in computational chemistry, computer science, chemistry, biophysics, or a related discipline Strong understanding of structure based and ligand based drug design, ideally including experience with macrocycles and peptides Experience with molecular modelling and visualisation platforms, e.g., PyMOL and MOE Experience with structural data (NMR and X ray crystallography) applied to molecular design problems A track record of high quality peer reviewed publications and conference presentations The ability to work effectively with customers, collaborators, and cross functional teams What We Offer We offer hybrid & flexible working, a competitive base salary, pension contribution, employee private medical and dental cover, life assurance, corporate gym discount and cycle to work scheme.