Cranleigh Scientific Ltd

Senior / Principal Scientist - Molecular Pharmacology Location:Reading Salary:Competitive Salary + Benefits Package We are supporting an innovative biotechnology organisation in the search for a Senior or Principal Scientist with expertise in molecular pharmacology and biologics discovery. This is an exciting opportunity for an experienced scientist to play a key role in advancing next generation therapeutic antibody programmes within a collaborative and fast paced research environment. This position would suit an experienced industry scientist with strong expertise across in vitro pharmacology, assay development, molecular and cell biology, and biologics discovery. The successful individual will contribute both strategically and hands on, helping shape discovery programmes while mentoring scientific colleagues and driving innovation across the organisation. The Opportunity As part of a growing discovery team, you will lead and contribute to the development of novel antibody and biologic therapeutics targeting important disease pathways. You will work cross functionally with research and development teams, applying scientific insight and technical expertise to support candidate identification and progression. This role offers the opportunity to influence scientific direction, implement new technologies, and contribute to the continued growth of a highly collaborative biotech environment. Key Responsibilities Lead the design, optimisation, validation, and execution of in vitro pharmacology and bioassay strategies Develop and implement screening cascades to identify and characterise lead therapeutic candidates Conduct mechanism of action studies and support preclinical biologics discovery programmes Drive assay development across a range of target classes and screening formats, including high throughput approaches Evaluate and introduce innovative technologies, instrumentation, and methodologies Collaborate closely with multidisciplinary teams across discovery, development, and manufacturing functions Mentor and support scientists across varying experience levels, fostering a collaborative team culture Analyse, interpret, and present scientific data to internal stakeholders and external collaborators Contribute to scientific strategy and support partnerships with external organisations where required About You We are looking for a scientifically curious and collaborative individual with a strong background in pharmacology and biologics discovery. You will bring a combination of technical expertise, leadership capability, and a proactive approach to problem solving. Essential Experience & Qualifications PhD in Pharmacology, Immunology, Molecular Biology, Cell Biology, Biochemistry, or a related scientific discipline Significant industry experience within biotechnology or pharmaceutical drug discovery environments Strong expertise in in vitro pharmacology, assay development, and molecular/cellular biology techniques Experience working on antibody or biologic therapeutic programmes Proven ability to lead scientific projects and mentor research teams Strong understanding of pharmacology principles and mechanism of action studies Experience analysing and interpreting complex biological datasets Excellent communication and collaboration skills across multidisciplinary teams

Cranleigh Scientific Ltd is recruiting a Scientist - Genotyping & Molecular Biology to join their laboratory team in Harlow, Essex. This role involves technical support, assay development, and contributions to PCR-based genotyping projects. The ideal candidate will have a degree in Molecular Biology or a related discipline and hands-on laboratory experience. Opportunities for growth in a collaborative and innovative biotech setting are available.

Scientist - Genotyping & Molecular Biology Location: Harlow, Essex (Onsite) Salary: £30,000 - £40,000 Contract: Permanent, Full Time We're recruiting for a growing biotechnology organisation seeking a Scientist - Genotyping & Molecular Biology to join their onsite laboratory team in Essex. This is a hands on opportunity for someone with a strong foundation in molecular biology who enjoys problem solving, assay development, and supporting customers with technical troubleshooting. Previous troubleshooting experience would be beneficial, although training can be provided. Experience with KASP or PACE technologies would also be advantageous. The Role This varied position combines laboratory science, technical support, quality control, and R&D activities. The successful candidate will contribute to PCR based genotyping projects while supporting customers and internal product development initiatives. The role would suit someone with previous R&D or troubleshooting laboratory experience who is looking to grow within a collaborative and scientifically driven environment. Key Responsibilities Provide technical support to customers via phone and email Troubleshoot customer assays and experimental workflows Design, optimise, and validate PCR based genotyping assays Carry out DNA extraction, quantification, and quality assessment Support internal R&D and new product development projects Perform QC testing on reagents, PCR master mixes, and instrumentation Assist with reagent manufacture and batch testing activities About You You will ideally be proactive, detail oriented, and comfortable working across a range of laboratory activities. Strong communication skills and a practical, problem solving mindset are important for success in this role. Essential Requirements Degree in Molecular Biology, Genetics, Plant Science, or a related discipline Hands on molecular biology laboratory experience Experience with PCR and DNA handling techniques Ability to work onsite in Harlow, Essex Right to work in the UK Desirable Experience PCR assay design and optimisation Genotyping workflows, particularly within plant or crop genetics Experience with KASP or PACE technologies DNA extraction from plant material Laboratory QC procedures Previous technical support or customer facing experience Apply If you're looking for an opportunity to develop your molecular biology career within an innovative and growing biotech environment, we'd love to hear from you.

Health & Safety Manager Telecomms / Utilities experience essential Location: Brentwood (with ad-hoc regional travel) Hybrid Working Available Salary: £55,000 - £70,000 DOE Our client is seeking an experienced Health & Safety Manager to lead and enhance Health, Safety, Environmental and Quality (HSEQ) practices across a growing operational business. This is a key leadership position responsible for embedding a positive safety culture, ensuring statutory compliance, and driving continuous improvement across multiple sites within the region. This role will suit a proactive and solutions-focused H&S professional who is confident working across operational teams, engaging with stakeholders, and influencing at all levels of the organisation. Safety Leadership & Culture Champion a strong, values-led safety culture across the business. Promote awareness through toolbox talks, training sessions and ongoing engagement initiatives. Lead by example, reinforcing high standards of safe working practices and procedural compliance. Compliance & Management Systems Develop, review and maintain Health & Safety policies, procedures and Risk Assessments and Method Statements (RAMS). Ensure full compliance with relevant UK legislation and industry best practice. Support and maintain ISO 9001, ISO 14001 and ISO 45001 management systems. Proactively identify hazards and implement control measures to mitigate operational risk and reduce external liabilities. Training & Capability Development Identify training needs to maintain workforce competence and compliance. Deliver and coordinate H&S training across operational and management teams. Provide guidance and support in the preparation and review of risk assessments and safe systems of work. Team & Contractor Oversight Provide leadership and direction to the internal H&S function, including site auditors. Oversee contractor and supply chain onboarding, ensuring adherence to required safety standards. Act as a key point of contact for client representatives in relation to H&S matters. Monitoring, Reporting & Continuous Improvement Conduct and oversee routine site inspections and audits. Investigate accidents, incidents and near misses, ensuring thorough root cause analysis and implementation of corrective actions. Produce regular performance reports, highlighting trends and recommending improvements. Support senior leadership with the development of project-specific HSEQ documentation and management plans. Candidate Profile NEBOSH or equivalent qualification as a minimum. Demonstrable experience in a similar senior H&S role within telecoms or utilities environments. Strong working knowledge of ISO 9001, ISO 14001 and ISO 45001 standards. Full UK driving licence and willingness to travel regionally. Competent in Microsoft Office applications, including Word, Excel and Outlook. Excellent communication skills with the ability to influence and engage stakeholders at all levels. What's on Offer Competitive salary of £55,000 - £70,000 DOE Company Van / Car Allowance and fuel card. Pension scheme and standard company benefits. Increasing annual leave entitlement with service. Ongoing professional development and training support. A collaborative working environment with a strong team ethos. This is an excellent opportunity for a motivated Senior Health & Safety professional to play a pivotal role in shaping and strengthening HSEQ standards within a dynamic and expanding organisation.

Cranleigh Scientific Ltd is seeking a Senior Scientist specialized in downstream analytics and bioprocessing techniques to join their team in Southampton. This position offers a hands-on role to help develop therapeutic solutions involving nucleic acids and peptides. The ideal candidate will have a PhD or equivalent and practical experience in HPLC, with strong skills in analytical innovation and team mentoring. Benefits include a competitive salary up to £50,000 and a generous holiday allowance.

Senior Scientist - Downstream Analytics (Large Molecules) Biotech HPLC Bioprocessing Southampton Up to £50,000 + Benefits We're partnering with an innovative scientific organisation to recruit a Senior Scientist with strong experience in downstream analytical processes, including HPLC and bioprocessing techniques, to join a high-performing team based in Southampton. This hands on role offers the chance to support the development of modified nucleic acids and peptides, drive analytical method development, and contribute to the advancement of large molecule therapeutics in a collaborative, fast paced environment. About the Role You'll take the lead on analytical workflows for nucleic acids, peptides, and antibodies, ensuring high standards of quality, compliance, and scientific rigour. The role will include method development, instrument maintenance, and cross-functional collaboration across R&D and production teams. This position is ideal for a scientist who enjoys working across disciplines, mentoring junior colleagues, and staying at the forefront of analytical innovation. Key Responsibilities Lead downstream analytical workflows using HPLC, UPLC, PAGE, flash chromatography, and related techniques Contribute to the purification and characterisation of large molecules, such as peptides and antibodies Support method development and continuous improvement in analytical approaches Collaborate with chemistry and production teams to support small molecule and oligonucleotide preparation Maintain, calibrate, and optimise analytical instrumentation in line with ISO and internal quality systems Mentor and support Associate Scientists and Lab Technicians Ensure accurate documentation and maintain data integrity across workflows Promote and uphold Health, Safety, and Environmental (HSE) standards Manage stock levels of analytical reagents and consumables Stay up to date on emerging trends in bioprocessing and analytical technologies About You We're looking for a motivated and collaborative scientist with a solid grounding in downstream analytical techniques and a passion for quality science. You'll ideally have: A PhD (or equivalent experience) in Analytical Chemistry, Biochemistry, or a related field Strong hands on experience in HPLC and bioprocessing within a biotechnology, pharmaceutical, or life sciences environment Knowledge of purification and characterisation methods for peptides, antibodies, or similar large molecules Experience with TFF or tangential flow filtration (advantageous) Familiarity with ISO or GMP-regulated environments Ability to lead technical projects and support team development Strong communication and problem solving skills A flexible, proactive mindset with strong attention to detail Salary & Benefits Salary: Up to £50,000 depending on experience Location: On site in Southampton Holidays: 25 days annual leave + 8 bank holidays Pension: 6% employer contribution Life Assurance: 4x salary Additional Benefits Include: Flexible working hours Long service awards and recognition scheme Employee Assistance Programme with 24/7 remote GP access Annual flu vaccinations Cycle to work scheme and gym discounts Discounts and savings platform Professional membership reimbursement Referral incentives Social events and volunteering days