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Full Stack Software Engineer required for a growing company with a high-volume customer facing website with over 1m annual customers. You'll be working across cloud-based software and mobile applications using TypeScript & React frontend with ExpressJS and PostgreSQL backend. The Full stack Software Engineer will focus on new product and feature development, playing a key role in a modern technology driven environment with access to the latest tools and training materials. You'll be working in a small but experienced team and have responsibility of leading projects and relevant engineering processes and principles. Essential Skills Full stack software development (3-5 years+) Typescript and ReactJS PostgreSQL SOLID principles DevOps understanding Desirable experience High traffic customer facing website or marketplace app experience AWS and Infrastructure as code Next JS or Express JS CI/CD pipeline management Flexibility: The hours are flexible, the working environment is relaxed, and you'll have freedom to work remotely with occasional office visits as little as twice a year. Please apply to this advert or email your CV direct to (url removed) Spectrum IT Recruitment (South) Limited is acting as an Employment Agency in relation to this vacancy.

Senior Laboratory Research Scientist - Chemical Biology STP Reports to Head, Chemical Biology Science Technology Platform This is a full-time, fixed term (three-year) position on Crick terms and conditions of employment About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role This exciting research project is a cross-Francis Crick Institute collaboration focussing on the translation of cutting-edge research led by Dr. Simon Boulton and carried out in the Double Strand Break (DSB) Metabolism Laboratory. Researchers in the DSB Metabolism Laboratory have identified several cellular processes that contribute alternative lengthening of telomeres (ALT) mechanism of telomere maintenance present in a sub set cancers (ALT positive cancers). This collaboration aims to translate the new ALT biology insights from the DSB Metabolism Laboratory into therapies to treat ALT positive cancers. This position will give scientists the opportunity to gain experience of drug discovery interfaced with cutting-edge disease biology, with guidance from experienced pharmaceutical research experts and world leaders in the field of DNA Damage Repair. This work is funded through a 3-year £3M programme of work supported by the philanthropic Chris Banton fund and LifeArc. The project brings together a growing team of scientists working across several laboratories and scientific technology platforms (STPs) at the Francis Crick Institute. What you will be doing We are seeking an ambitious and creative cellular assay biologist, with small molecule discovery experience, to join the Chemical Biology STP at the Francis Crick Institute. The successful applicant will work flexibility across the Chemical Biology and High Throughput Screening STPs, drawing on the expertise and capability to be found in both groups. You will be an integral part of the ongoing drug discovery project to identify, characterise and optimise chemical leads for the newly elucidated ALT-dependent cellular processes. The ALT project is highly multidisciplinary, comprising scientists from a variety of backgrounds in an integrated academia-industry setting. In collaboration with the ALT project team, you will develop assays to support the elucidation of detailed molecular mechanism of action of new chemical tools and will work with disease biologists to translate these findings into more biologically relevant systems. You will also work with medicinal and computational chemists to help optimise the chemical tools, designing assay systems to inform on structure activity relationships and drive compound optimisation. You will be a be a goal-orientated multitasker and an independent thinker, with the ability to initiate and run projects, as well as co-lead collaborative teams, taking advantage of the many training opportunities this work will provide. If you are someone who thrives in dynamic, fast- paced and creative environments, this may be a great opportunity for you to join the lab and this project. As a Senior Laboratory Research Scientist at the Crick, you will: Have a responsibility for assay development, screening and mechanistic studies for one of the protein targets of interest. Develop, optimise and routinely use cellular mechanistic assays, such as NanoBRET to elucidate cell target engagement and intracellular residence time. Optimise and implement biochemical (FP, TR-FRET, FLINT, Alpha) and biophysical (SPR, DSF, Nanotemper) assays to identify and optimise hits to generate high quality ALT tool compounds. Establish new capability and technologies to enable novel insights into the ALT targets. See the full job description Read more about the STP About you The post holder should embody and demonstrate our core Crick values: Bold, Open, and Collegial, in addition to the following: Essential: PhD (or equivalent experience level) in a relevant discipline such as cell or molecular biology, biochemistry or chemical biology, A strong track record of developing and carrying out innovative assay solutions to address chemical biology or medicinal chemistry questions in academic or industrial research, ideally supported by publications in peer-reviewed journals. Practical experience of mammalian cell culture techniques for the development of recombinant cellular assays. Experience and knowledge of cellular target engagement technologies such as NanoBRET. Knowledge and/or practical experience of molecular biology (for the preparation of recombinant proteins or cellular assays) and protein biology. About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: Find out more about life at the Crick here. What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure with performance-linked progression.

Your new company Hays Technology are recruiting a Head of Cyber Security & Infrastructure to join an exciting and growing public sector organisation based nationally. You will be reporting to the Director of Technology. Your new role In your role, you will be overseeing the Cyber Security estate, adhering to the Cyber Assessment Framework, and continuously improving the internal security posture, identifying and assessing any cyber security risks, in accordance with laws and regulations. You will be responsible for leveraging and optimising a number of tools including, MS Defender, Sentinel, Azure and the external SOC partner to enhance cyber resilience, conduct threat analysis, and proactive risk assessments to design effective controls. You will be leading the Cyber Security operations function, by providing strategic direction and coordinating day-to-day delivery of threat intelligence, threat detection, incident response, vulnerability management, and ethical hacking capabilities. You will be leading a team of Infrastructure Engineers, ensuring strong data controls are in place, whilst working closely with key stakeholders to establishing responsibilities and ensure an end-to-end approach to cyber resilience Is embedded in other functions. What you'll need to succeed Extensive understanding of Azure, MS Defender, Sentinel, and Cyber Assessment Framework Experience leading a team of security and infrastructure engineers Extensive experience of creating cyber security roadmaps Experience of building and implementing strong operational processes Excellent communication skills with the ability to translate business requirements into technical solutions Strong stakeholder management skills What you'll get in return This exciting position is paying between 70,000 and 80,000 negotiable on experience and offers an excellent work life balance including: remote working, great annual leave allowance, public sector employer contribution pension scheme, flexibility, training, and development opportunities. What you need to do now If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call us now. Hays Specialist Recruitment Limited acts as an employment agency for permanent recruitment and employment business for the supply of temporary workers. By applying for this job you accept the T&C's, Privacy Policy and Disclaimers which can be found at (url removed)

IT Support Engineer - First line support Rochester ME1 3QX 26-30,000 8.30am-5.30pm Monday - Friday We are seeking a First Line IT Engineer to join our growing managed service help desk. This is a very exciting time to join a thriving business where growth and development is certain! The First Line Engineer will be responsible for providing technical support to our clients and ensuring their IT systems are functioning optimally. Responsibilities of an IT support technician Respond to technical support requests from clients via phone, email, or ticketing system. Troubleshoot and resolve technical issues related to hardware, software, and networking. Provide support for clients' desktop and laptop computers, printers, mobile devices, and other technology equipment. Document technical issues and solutions in a clear and concise manner. Escalate complex issues to senior engineers as needed. Requirements of first line support technician : 1+ years of experience in technical support or a related field. Knowledge of Windows, Microsoft Office and Microsoft 365 Familiarity with network infrastructure and basic networking concepts. Excellent customer service and communication skills. Ability to work independently and as part of a team. If you are passionate about technology and customer service and have a desire to grow your career in the managed services industry, we would love to hear from you. Contact Sarah Gilbertson Netbox Recruitment to gain full job details

Job Title: Principal Naval Architect Location: Barrow-in-Furness, Brough, Frimley, Weymouth, Filton, Portsmouth or Manchester. We offer a range of hybrid and flexible working arrangements - please speak to your recruiter about the options for this particular role Salary: £45,628 plus depending on experience What you'll be doing: Designing the SSN AUKUS which is now the world's most advanced Submarine Using your knowledge of hydrostatics, hydrodynamics, seamanship and outfit, infrastructure or whole boat design to support the largest shipbuilding programmes in the UK Supporting with sea trials, inclining experiments and other commissioning activities for multiple submarine classes Undertaking research and development activities to develop world leading capabilities Writing and presenting technical reports Your skills and experiences: Essential: Demonstrable experience as a Naval Architect Chartered Engineer or working towards Chartered status Desirable: Degree in Naval Architecture Experience in ship design analysis and build support Advanced numeracy and analytical skills Previous experience working on defence projects Benefits: You'll receive benefits including a competitive pension scheme, enhanced annual leave allowance and a Company contributed Share Incentive Plan. You'll also have access to additional benefits such as flexible working, an employee assistance programme, Cycle2work and employee discounts - you may also be eligible for an annual incentive. The Naval Architecture team: As a Principal Naval Architect, you will be an important member in one of the largest and fastest growing Naval Architecture Departments in the UK. You will be working on some of the most complex ship design and build programmes ever undertaken to deliver cutting edge submarines to the Royal Navy and Royal Australian Navy. This role will provide you with the chance to work on submarines at all stages of the product life cycle from early design to build support and commission. The Naval Architecture Department comprises teams specialising weights engineering, stability and hydrostatics, infrastructure support, seamanship and outfit, manoeuvring and control, fluid dynamics, design and development. Depending on your location, the role will involve working one day a week on site, with expectation to travel to Barrow for work commitments. We offer relocation support packages across all Submarines roles, subject to meeting eligibility criteria. Why BAE Systems? This is a place where you'll be able to make a real difference. You'll be part of an inclusive culture that values diversity of thought, rewards integrity, and merit, and where you'll be empowered to fulfil your potential. We welcome people from all backgrounds and want to make sure that our recruitment processes are as inclusive as possible. If you have a disability or health condition (for example dyslexia, autism, an anxiety disorder etc.) that may affect your performance in certain assessment types, please speak to your recruiter about potential reasonable adjustments. Please be aware that many roles at BAE Systems are subject to both security and export control restrictions. These restrictions mean that factors such as your nationality, any nationalities you may have previously held, and your place of birth can restrict the roles you are eligible to perform within the organisation. All applicants must as a minimum achieve Baseline Personnel Security Standard. Many roles also require higher levels of National Security Vetting where applicants must typically have 5 to 10 years of continuous residency in the UK depending on the vetting level required for the role, to allow for meaningful security vetting checks. Closing Date: 2nd June 2025 We reserve the right to close this vacancy early if we receive sufficient applications for the role. Therefore, if you are interested, please submit your application as early as possible.

FINTEC recruit is supporting recruitment for a Cyber Security (SOC) Lead. This is a permanent position, based in Hemel Hempstead, working rotation of 2 days on / 2 nights on & then 4 days office, (hours are 6 am. To 6 pm, then 6 pm to 6 am). Salaries discussed on application and negotiable by experience. There is a required to pass UK Security Clearance (DV level). You will be supporting critical infrastructure within aerospace, defence and security sectors. Able to drive operational improvements, working onsite, leading and mentoring a small team. Responsibilities: Monitoring, triaging, and investigating alerts across host and network security systems Performing deep analysis of traffic, logs, and system events to identify threats and vulnerabilities Providing mentoring & line management to SOC Analysts Enhancing team knowledge across SOC tooling, detection methodologies, and threat triage Analyse and optimise detection rules and use cases based on Mitre Att&ck Maintaining detailed and up-to-date incident documentation, findings, and mitigation strategies Acting as a representative of the SOC in key meetings and internal stakeholder engagements Skills and Experience required for the Cyber Security SOC Lead role: Proven experience in a Security Operations Centre (SOC) environment Qualified at SOC Level 2 Strong familiarity with SIEM platforms including Microsoft Sentinel and Splunk Knowledge and use of the Mitre Att&ck Framework for detection and threat analysis Experience of static malware analysis and reverse engineering (desirable) Scripting or programming with Python, Perl, Bash, PowerShell or C++ (desirable not an essential) SIEM technologies knowledge such as QRadar (desirable not an essential) In-depth understanding of : Client-server applications and multi-tier web environments Relational databases, firewalls, VPNs, enterprise AntiVirus solutions Full details of the Cyber Security SOC lead role is available on application. To apply please submit your current CV or apply via our FINTEC recruit website

VMware Engineer - MUST HAVE A VALID DV We are seeking a VMware Engineer to join an established deployment team working on a major hardware rollout for a large government account. The role will be fully onsite in Bracknell, and you will play a key part in the configuration and deployment of ESX devices as part of a wider infrastructure programme. Key Responsibilities: Build and configure VMware ESX hosts according to detailed build guides within a project deployment environment. Install hardware onsite, including racking and cabling activities as required. Provide remote support during hardware testing phases to assist with technical validation. Engage with internal service teams to ensure successful handover and support of newly deployed hardware. Deliver regular updates on progress and issues to the Project Manager and team leads. Support occasional out-of-hours work due to the nature of customer operations. Essential Skills & Experience: Demonstrated experience as an Infrastructure Engineer in project-based environments, particularly building from structured documentation. Solid technical background across enterprise infrastructure, including strong VMware / vSphere experience. Comfortable working independently with minimal supervision, proactively resolving issues and identifying root causes. Strong collaboration and interpersonal skills, with a proven ability to work effectively within technical teams and with wider stakeholders. Clear and professional communication skills, both written and verbal. Excellent attention to detail and ability to follow process and documentation precisely. Previous experience working with large government clients or in secure environments. Positive, can-do attitude with a solution-focused mindset. This is a fantastic opportunity for a motivated and technically capable engineer to contribute to a high-impact government infrastructure programme. You'll be working alongside skilled professionals in a secure environment, helping to deliver mission-critical solutions.

Senior Laboratory Research Scientist (SLRS) - Boulton lab Reports to: Dr Simon Boulton This is a full-time, fixed term (three-year) position on Crick terms and conditions of employment Working pattern: Monday - Friday. About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role This exciting research project is a cross-Francis Crick Institute collaboration focussing on the translation of cutting-edge research led by Dr. Simon Boulton and carried out in the Double Strand Break (DSB) Metabolism Laboratory. Researchers in the DSB Metabolism Laboratory have identified several cellular processes that contribute to the alternative lengthening of telomeres (ALT) mechanism of telomere maintenance present in a sub set cancers (ALT positive cancers). This collaboration aims to translate the new ALT biology insights from the DSB Metabolism Laboratory into therapies to treat ALT positive cancers. This position will give scientists the opportunity to gain experience of drug discovery interfaced with cutting-edge disease biology, with guidance from experienced pharmaceutical research experts and world leaders in the field of DNA Damage Repair. This work is funded through a 3-year £3M programme of work supported by the philanthropic Chris Banton fund and LifeArc. The project brings together a growing team of scientists working across several laboratories and scientific technology platforms (STPs) at the Francis Crick Institute. What you will be doing We are looking for an ambitious and creative cell biologist, ideally with telomere biology experience, to join the ALT programme team at the Francis Crick Institute. You will be an integral part of the ongoing target validation and drug discovery project to identify, characterise and optimise chemical leads for the newly elucidated ALT-dependent cellular processes. The ALT project is highly multidisciplinary, comprising scientists from a variety of backgrounds in an integrated academia-industry setting. In collaboration with the ALT project team, you will contribute to the validation and elucidation of detailed molecular mechanism of action of new ALT targets and the development of cell-active chemical tools to translate these findings into more biologically relevant systems. In parallel, you will work with postdoctoral scientists in the Boulton lab and computational chemists, structural biologists and biophysicist to help optimise the chemical tools, designing cellular assay systems to inform on structure activity relationships and drive compound optimisation. You will be a be a goal-orientated multitasker and an independent thinker, with the ability to initiate and run projects, as well as co-lead collaborative teams, taking advantage of the many training opportunities this work will provide. If you are someone who thrives in dynamic, fast- paced and creative environments, this may be a great opportunity for you to join the lab. As a Senior Laboratory Research Scientist at the Crick, your key responsibilities will include: Validation of ALT targets validation and characterisation of the underlying mechanisms of action, including potential resistance mechanisms. Development, optimisation and routine use of cellular mechanistic assays utilising ALT markers such as TIFs, APBs, C-circles, ssTELOC/G and ALT-DNA synthesis to elucidate target engagement. Establishing new capability and technology development to enable novel insights into the ALT targets. Screening of novel chemical modulators of ALT and characterisation of the mechanisms of action. Routine and thorough capture of all assay data in an ELN, such as Dotmatics. See the full job description. Read more about the lab. About you You will bring PhD (or equivalent experience level) in a relevant discipline such as cell and/or molecular biology. A strong track record of target validation and mechanistic analysis using innovative cellular assays in academic or industrial research, ideally supported by publications in peer-reviewed journals. Practical experience of mammalian cell culture techniques for the development of cellular assays, ideally with an understanding of genome/telomere maintenance processes. Knowledge and/or practical experience of cell and molecular biology. About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: To find out more about life at the Crick click here . What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure with performance-linked progression.

VMware Engineer - MUST HAVE A VALID DV We are seeking a VMware Engineer to join an established deployment team working on a major hardware rollout for a large government account. The role will be fully onsite in Bracknell, and you will play a key part in the configuration and deployment of ESX devices as part of a wider infrastructure programme. Key Responsibilities: Build and configure VMware ESX hosts according to detailed build guides within a project deployment environment. Install hardware onsite, including racking and cabling activities as required. Provide remote support during hardware testing phases to assist with technical validation. Engage with internal service teams to ensure successful handover and support of newly deployed hardware. Deliver regular updates on progress and issues to the Project Manager and team leads. Support occasional out-of-hours work due to the nature of customer operations. Essential Skills & Experience: Demonstrated experience as an Infrastructure Engineer in project-based environments, particularly building from structured documentation. Solid technical background across enterprise infrastructure, including strong VMware / vSphere experience. Comfortable working independently with minimal supervision, proactively resolving issues and identifying root causes. Strong collaboration and interpersonal skills, with a proven ability to work effectively within technical teams and with wider stakeholders. Clear and professional communication skills, both written and verbal. Excellent attention to detail and ability to follow process and documentation precisely. Previous experience working with large government clients or in secure environments. Positive, can-do attitude with a solution-focused mindset. This is a fantastic opportunity for a motivated and technically capable engineer to contribute to a high-impact government infrastructure programme. You'll be working alongside skilled professionals in a secure environment, helping to deliver mission-critical solutions.

Senior Laboratory Research Scientist (SLRS) - Crystallography/Drug Discovery Reports to Head: Structural Biology Science Technology Platform This is a full-time, fixed term (three-year) position on Crick terms and conditions of employment Working pattern: Monday - Friday About us The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy. About the role This exciting research project is a cross-Francis Crick Institute collaboration focussing on the translation of cutting-edge research led by Dr. Simon Boulton and carried out in the Double Strand Break (DSB) Metabolism Laboratory. Researchers in the DSB Metabolism Laboratory have identified several cellular processes that contribute to the alternative lengthening of telomeres (ALT) mechanism of telomere maintenance present in a sub set cancers (ALT positive cancers) This collaboration aims to translate the new ALT biology insights from the DSB Metabolism Laboratory into therapies to treat ALT positive cancers. This position will give scientists the opportunity to gain experience of drug discovery interfaced with cutting-edge disease biology, with guidance from experienced pharmaceutical research experts and world leaders in the field of DNA Damage Repair. This work is funded through a 3-year £3M programme of work supported by the philanthropic Chris Banton fund and LifeArc. The project brings together a growing team of scientists working across several laboratories and scientific technology platforms (STPs) at the Francis Crick Institute. What you will be doing We are looking for a creative and highly motivated structural biologist with a strong background in crystallography and drug discovery to support early-stage drug discovery/probe development on ALT project. You will work within the Structural Biology Science Technology Platform (SB STP) which spans a variety of protein technologies (protein expression and purification), biophysics, X-ray crystallography and cryo-EM. The STP collaborates with researchers at the Crick to explore biological questions, working at the cutting edge of biomedical science in disciplines such as cancer, infectious disease, immunology, neurology, and developmental biology. You will be responsible for the post holder will be responsible for all aspects of the protein structure determination experimental process; sample preparation, data collection/processing, structure determination and data presentation. The post holder is expected to contribute to on-going projects and process optimisation projects. As a Senior Laboratory Research Scientist at the Crick, you will: Enable robust purification protocols of high purity, homogeneous recombinant protein samples for structural biology, biophysics and bioassay studies. Determine crystal structures of target protein bound to fragments/compounds. Train and supervise junior team members or students. Be responsible for maintenance of significant up-to-date knowledge of relevant literature, communication of key developments to other lab members and the institute, implementation of new techniques to own research. About you You will bring PhD in structural biology with post-doctoral (or equivalent) experience. Extensive experience in molecular cloning, recombinant protein expression and automated purification using ĀKTA workstations and a range of chromatographic techniques. Expertise in a suite of biophysical quality control methods to ensure crystallography grade protein preparations. Extensive experience in protein X-ray crystallography techniques, including initial crystallisation and optimisation (using robots such as Mosquito, NT8), data collection, structure determination and structure refinement Experience with standard crystallographic software packages, such as CCP4, CCP4cloud, Phenix, and Coot Deep knowledge of high throughput crystallography. See the full job description Read more about the STP About Working at the Crick Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture! We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: Find out more about life at the Crick. What will you receive? At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development: Visas: Applicants for this role will be eligible for sponsorship to work in the UK Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays. Pension Scheme: Defined contribution pension with employer contributions of up to 16%. Health & Well-being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans. Work-Life Balance: Back-up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups' support, community and inclusive social events. Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts. Subsidised on-site restaurant and social spaces for team interaction. Development & Recognition: Comprehensive training, mentoring, and a pay structure with performance-linked progression.

Job Description We know that people want great value combined with an excellent experience from a bank they can trust, so we launched our digital bank, Chase UK, to revolutionise mobile banking with seamless journeys that our customers love. We're already trusted by millions in the US and we're quickly catching up in the UK - but how we do things here is a little different. We're building the bank of the future from scratch, channelling our start-up mentality every step of the way - meaning you'll have the opportunity to make a real impact. As a Principal MLOps Engineer at JPMorgan Chase within the International Consumer Bank, you provide deep engineering expertise and work across agile teams to enhance, build, and deliver trusted market-leading technology products in a secure, stable, and scalable way . You are expected to be involved in the design and architecture of the solutions while also focusing on the entire SDLC lifecycle stages. Our Machine Learning Operations team is at the heart of this venture, focused on getting smart ideas into the hands of our customers. We're looking for people who have a curious mindset, thrive in collaborative squads, and are passionate about new technology. By their nature, our people are also solution-oriented, commercially savvy and have a head for fintech. We work in tribes and squads that focus on specific products and projects - and depending on your strengths and interests, you'll have the opportunity to move between them. Job responsibilities : Advise and leads development of tooling for AI/ML development and deployment. Lead deployment and maintenance of infrastructure, model monitoring and observability tools, providing an effective model development platform for data scientists and ML engineers. Collaborate with machine learning model developers to bring ML models to production. Mentor and leads a team of engineers focused on deploying machine learning pipelines at scale. Partner with product, architecture, and other engineering teams to define scalable and performant technical solutions. Influence across business, product, and technology teams and successfully manages senior stakeholder relationships Champion the firm's culture of diversity, equity, inclusion, and respect. Required qualifications, capabilities and skills Formal training or certification on software engineering concepts and MLOps applied experience. Experience with machine learning engineering and operations in a large enterprise. Experience in building, evaluating and deploying ML models into production Experience leading complex projects supporting system design, testing and operational stability. Demonstrated prior experience influencing across complex organizations and delivering value at scale. Extensive practical cloud native experience Proven expertise on adoption of agile practices to deliver efficiently and to the expected quality solutions. . About Us J.P. Morgan is a global leader in financial services, providing strategic advice and products to the world's most prominent corporations, governments, wealthy individuals and institutional investors. Our first-class business in a first-class way approach to serving clients drives everything we do. We strive to build trusted, long-term partnerships to help our clients achieve their business objectives. We recognize that our people are our strength and the diverse talents they bring to our global workforce are directly linked to our success. We are an equal opportunity employer and place a high value on diversity and inclusion at our company. We do not discriminate on the basis of any protected attribute, including race, religion, color, national origin, gender, sexual orientation, gender identity, gender expression, age, marital or veteran status, pregnancy or disability, or any other basis protected under applicable law. We also make reasonable accommodations for applicants' and employees' religious practices and beliefs, as well as mental health or physical disability needs. Visit our FAQs for more information about requesting an accommodation. About The Team Our professionals in our Corporate Functions cover a diverse range of areas from finance and risk to human resources and marketing. Our corporate teams are an essential part of our company, ensuring that we're setting our businesses, clients, customers and employees up for success.

Job Title: Principal Naval Architect Location: Barrow-in-Furness, Brough, Frimley, Weymouth, Filton, Portsmouth or Manchester. We offer a range of hybrid and flexible working arrangements - please speak to your recruiter about the options for this particular role Salary: £45,628 plus depending on experience What you'll be doing: Designing the SSN AUKUS which is now the world's most advanced Submarine Using your knowledge of hydrostatics, hydrodynamics, seamanship and outfit, infrastructure or whole boat design to support the largest shipbuilding programmes in the UK Supporting with sea trials, inclining experiments and other commissioning activities for multiple submarine classes Undertaking research and development activities to develop world leading capabilities Writing and presenting technical reports Your skills and experiences: Essential: Demonstrable experience as a Naval Architect Chartered Engineer or working towards Chartered status Desirable: Degree in Naval Architecture Experience in ship design analysis and build support Advanced numeracy and analytical skills Previous experience working on defence projects Benefits: You'll receive benefits including a competitive pension scheme, enhanced annual leave allowance and a Company contributed Share Incentive Plan. You'll also have access to additional benefits such as flexible working, an employee assistance programme, Cycle2work and employee discounts - you may also be eligible for an annual incentive. The Naval Architecture team: As a Principal Naval Architect, you will be an important member in one of the largest and fastest growing Naval Architecture Departments in the UK. You will be working on some of the most complex ship design and build programmes ever undertaken to deliver cutting edge submarines to the Royal Navy and Royal Australian Navy. This role will provide you with the chance to work on submarines at all stages of the product life cycle from early design to build support and commission. The Naval Architecture Department comprises teams specialising weights engineering, stability and hydrostatics, infrastructure support, seamanship and outfit, manoeuvring and control, fluid dynamics, design and development. Depending on your location, the role will involve working one day a week on site, with expectation to travel to Barrow for work commitments. We offer relocation support packages across all Submarines roles, subject to meeting eligibility criteria. Why BAE Systems? This is a place where you'll be able to make a real difference. You'll be part of an inclusive culture that values diversity of thought, rewards integrity, and merit, and where you'll be empowered to fulfil your potential. We welcome people from all backgrounds and want to make sure that our recruitment processes are as inclusive as possible. If you have a disability or health condition (for example dyslexia, autism, an anxiety disorder etc.) that may affect your performance in certain assessment types, please speak to your recruiter about potential reasonable adjustments. Please be aware that many roles at BAE Systems are subject to both security and export control restrictions. These restrictions mean that factors such as your nationality, any nationalities you may have previously held, and your place of birth can restrict the roles you are eligible to perform within the organisation. All applicants must as a minimum achieve Baseline Personnel Security Standard. Many roles also require higher levels of National Security Vetting where applicants must typically have 5 to 10 years of continuous residency in the UK depending on the vetting level required for the role, to allow for meaningful security vetting checks. Closing Date: 2nd June 2025 We reserve the right to close this vacancy early if we receive sufficient applications for the role. Therefore, if you are interested, please submit your application as early as possible.

Planner required to join a consultancy, focusing on high-profile infrastructure projects across a variety of sectors. These include Infrastructure, Airports, Civils, Nuclear, and Defence projects. The successful candidate will be responsible for developing, maintaining, and monitoring detailed project schedules using Primavera P6. This role requires a collaborative approach, working closely with project teams to ensure the efficient planning and execution of project objectives. As a Planner, you will provide strategic input, support project control processes, and produce progress reports while liaising with risk managers to mitigate potential project risks. Skills: Proficiency in Primavera P6 Experience in Civil/Infrastructure engineering Strong communication and influencing abilities Knowledge of project management and control processes Analytical skills for activity assessment and process matching Ability to lead schedule development Experience with Earned Value Management Understanding of risk assessment and mitigation Competence in stakeholder engagement Demonstrable experience in infrastructure project planning Software/Tools: Primavera P6 Microsoft PowerPoint Certifications & Standards: Knowledge of relevant industry standards and best practices (e.g., NEC contracts) Potential membership in professional bodies such as CIOB or MICE

Company Description Work with Us. Change the World. At AECOM, we're delivering a better world. Whether improving your commute, keeping the lights on, providing access to clean water, or transforming skylines, our work helps people and communities thrive. We are the world's trusted infrastructure consulting firm, partnering with clients to solve the world's most complex challenges and build legacies for future generations. There has never been a better time to be at AECOM. With accelerating infrastructure investment worldwide, our services are in great demand. We invite you to bring your bold ideas and big dreams and become part of a global team of over 50,000 planners, designers, engineers, scientists, digital innovators, program and construction managers and other professionals delivering projects that create a positive and tangible impact around the world. We're one global team driven by our common purpose to deliver a better world. Join us. Job Description Start here. Grow here. Are you ready to lead a team of talented engineers and shape the future of energy infrastructure? AECOM is a leading provider of engineering, environment and construction services, and is contributing its deep experience to help strategically plan, develop, design and construct energy infrastructure to not only meet future demands but to deliver sustainable legacies for our clients, community and our planet. We look at our projects as part of the broader energy system and across the whole life cycle, from commissioning to decommissioning. We help our clients achieve the right balance across the spectrum of generation through renewable energy sources, solar, wind, stored energy, hydropower and fossil fuels; and alternative energy fuels including hydrogen and electrification. About our Team The Transmission & Distribution (T&D) Engineering team provides a range of services from the initial concept through Power Systems Analysis, Cabling, Substations, Transmission and Distribution Infrastructure, System Balancing and Compensation, Protection Systems, SCADA, Communications, Converter Station Design, HVDC Systems and Interconnectors including overseas links. Job Description In this leadership role, you will be a key member of our Transmission & Distribution team dedicated to engaging with our clients and directly contributing to the successful delivery of ground breaking and technically challenging civil design projects encompassing the T&D projects. This is a new specialist associate director level role in combination with integrated project management and delivery to support the growth of our UK & Ireland T&D practice. Here's what you'll do: You will provide technical engineering expertise in delivering design the civil engineering aspects of power transmission and distribution projects. This includes creating the civil design plans for substations, transmission towers, and underground cable systems. Also, to produce detailed drawings, specifications, and design documents using software like AutoCAD, Civil 3D, and Revit. Provide engineering expertise from the concept to detailed design of transmission & distribution projects, including substations, power generating stations, data centres, BESS and renewables. Checking and review engineering deliverables such as complex designs, reports, proposals, presentations, and drawing packages. You'll provide technical expertise in bids and proposals and represent the Company in client meetings as a senior member of the Civils team, applying your experience and expertise to a range of exciting and interesting projects. Take responsibility for assigned project scope, technical delivery, and client engagement for civil works within projects. You will have the opportunity to be involved in large programmes of work like Great Grid Upgrade (GGP) projects. Provide expert technical evaluations and offer problem-solving solutions to different team members. Contribute to written proposals outlining all project details, including the timeline, resources, budget, objectives, and goals. Ensure your work meets safety, health, environmental, sustainability, and quality standards. Ensure adherence to AECOM and client design management processes while leading project and client meetings as needed. Actively participating in business and strategic planning activities to identify opportunities to continue the growth of the business in the short, medium and longer-term. Mentoring team members in their development, facilitating opportunities that build competency, and assisting with professional accreditation where appropriate. You will have the opportunity to collaborate with our Global Enterprise Capabilities teams to deliver projects in the region. Ensure design submissions comply with codes, standards, and quality requirements. Enjoy the Perks. At AECOM, you'll enjoy a range of core and personalised benefits designed to support your future and well-being, customised to fit your lifestyle. Take advantage of career development opportunities, our flexible hybrid working model to ensure a work-life balance that suits your lifestyle, technical practice networks, AECOM University, and volunteering days. Qualifications What are we looking for from you? Significant experience in UK development-related infrastructure engineering; likely from a private/consultancy background. Civil Engineering degree with over 10 years of civil engineering experience supporting utility clients, with involvement in projects related to one or more of the following facility types: electrical transmission and distribution, onshore wind, solar energy, BESS and electrical substations Specialized in civil engineering components of utility infrastructure projects, including site layout planning, access road and driveway geometric design, grading, drainage, and interdisciplinary coordination. Working experience with the National Grid projects is advantageous. Chartership & Lead CDAE/CDAE certifications are advantageous. Excellent written and verbal communication skills We celebrate diversity, including neurodiversity, and believe it enriches our team. We welcome applications from all backgrounds and abilities. If you are an applicant with a disability that requires reasonable accommodation to complete the application process, please contact us at . At AECOM, we value everyone's unique contributions and perspectives. If you meet some of the requirements above or have transferable skills you believe would benefit us, we would be delighted to hear from you! Additional Information Interested in the role or curious about life at AECOM? Follow us on LinkedIn, Facebook, Instagram, and YouTube to explore our AECOM voices, employee stories, latest projects, and much more! For further information about the role, reach out to the recruiter on LinkedIn (Francesca Siddle) About AECOM AECOM is the world's trusted infrastructure consulting firm, delivering professional services throughout the project lifecycle - from advisory, planning, design and engineering to program and construction management. On projects spanning transportation, buildings, water, new energy and the environment, our public- and private-sector clients trust us to solve their most complex challenges. Our teams are driven by a common purpose to deliver a better world through our unrivaled technical and digital expertise, a culture of equity, diversity and inclusion, and a commitment to environmental, social and governance priorities. AECOM is a Fortune 500 firm and its Professional Services business had revenue of $14.4 billion in fiscal year 2023. See how we are delivering sustainable legacies for generations to come at Freedom to Grow in a World of Opportunity You will have the flexibility you need to do your best work with hybrid work options. Whether you're working from an AECOM office, remote location or at a client site, you will be working in a dynamic environment where your integrity, entrepreneurial spirit and pioneering mindset are championed. You will help us foster a safe and respectful workplace, where we invite everyone to bring their whole selves to work using their unique talents, backgrounds and expertise to create transformational outcomes for our clients. AECOM provides a wide array of compensation, benefits and well-being programs to meet the diverse needs of our employees and their families. We're the world's trusted global infrastructure firm, and we're in this together - your growth and success are ours too. Join us, and you'll get all the benefits of being a part of a global, publicly traded firm - access to industry-leading technology and thinking and transformational work with big impact and work flexibility. As an Equal Opportunity Employer, we believe in each person's potential, and we'll help you reach yours. We are a Disability Confident Employer and will offer an interview to applicants who have a disability or long-term condition, who meet the minimum/essential criteria for the role. Please let us know using this email address if you would like to apply through the Disability Confident Interview Scheme. All your information will be kept confidential according to EEO guidelines. ReqID: J Business Line: Energy Business Group: DCS . click apply for full job details

Job Title: Principal Naval Architect Location: Barrow-in-Furness, Brough, Frimley, Weymouth, Filton, Portsmouth or Manchester. We offer a range of hybrid and flexible working arrangements - please speak to your recruiter about the options for this particular role Salary: £45,628 plus depending on experience What you'll be doing: Designing the SSN AUKUS which is now the world's most advanced Submarine Using your knowledge of hydrostatics, hydrodynamics, seamanship and outfit, infrastructure or whole boat design to support the largest shipbuilding programmes in the UK Supporting with sea trials, inclining experiments and other commissioning activities for multiple submarine classes Undertaking research and development activities to develop world leading capabilities Writing and presenting technical reports Your skills and experiences: Essential: Demonstrable experience as a Naval Architect Chartered Engineer or working towards Chartered status Desirable: Degree in Naval Architecture Experience in ship design analysis and build support Advanced numeracy and analytical skills Previous experience working on defence projects Benefits: You'll receive benefits including a competitive pension scheme, enhanced annual leave allowance and a Company contributed Share Incentive Plan. You'll also have access to additional benefits such as flexible working, an employee assistance programme, Cycle2work and employee discounts - you may also be eligible for an annual incentive. The Naval Architecture team: As a Principal Naval Architect, you will be an important member in one of the largest and fastest growing Naval Architecture Departments in the UK. You will be working on some of the most complex ship design and build programmes ever undertaken to deliver cutting edge submarines to the Royal Navy and Royal Australian Navy. This role will provide you with the chance to work on submarines at all stages of the product life cycle from early design to build support and commission. The Naval Architecture Department comprises teams specialising weights engineering, stability and hydrostatics, infrastructure support, seamanship and outfit, manoeuvring and control, fluid dynamics, design and development. Depending on your location, the role will involve working one day a week on site, with expectation to travel to Barrow for work commitments. We offer relocation support packages across all Submarines roles, subject to meeting eligibility criteria. Why BAE Systems? This is a place where you'll be able to make a real difference. You'll be part of an inclusive culture that values diversity of thought, rewards integrity, and merit, and where you'll be empowered to fulfil your potential. We welcome people from all backgrounds and want to make sure that our recruitment processes are as inclusive as possible. If you have a disability or health condition (for example dyslexia, autism, an anxiety disorder etc.) that may affect your performance in certain assessment types, please speak to your recruiter about potential reasonable adjustments. Please be aware that many roles at BAE Systems are subject to both security and export control restrictions. These restrictions mean that factors such as your nationality, any nationalities you may have previously held, and your place of birth can restrict the roles you are eligible to perform within the organisation. All applicants must as a minimum achieve Baseline Personnel Security Standard. Many roles also require higher levels of National Security Vetting where applicants must typically have 5 to 10 years of continuous residency in the UK depending on the vetting level required for the role, to allow for meaningful security vetting checks. Closing Date: 2nd June 2025 We reserve the right to close this vacancy early if we receive sufficient applications for the role. Therefore, if you are interested, please submit your application as early as possible.